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Volumn 287, Issue 44, 2012, Pages 37552-37563

β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel

Author keywords

[No Author keywords available]

Indexed keywords

ARRESTINS; INFLAMMATORY DISORDERS; IONOTROPIC RECEPTORS; LIGAND-GATED ION CHANNELS; MULTIPLE CELL MODEL; PHOSPHODIESTERASES; SCAFFOLD PROTEIN; SCAFFOLDING PROTEINS; TRANSIENT RECEPTOR POTENTIAL VANILLOID;

EID: 84868218099     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.391847     Document Type: Article
Times cited : (44)

References (60)
  • 3
    • 0142059776 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
    • Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., and Gereau, R. W., 4th (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc. Natl. Acad. Sci. U.S.A. 100, 12480-12485
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 12480-12485
    • Bhave, G.1    Hu, H.J.2    Glauner, K.S.3    Zhu, W.4    Wang, H.5    Brasier, D.J.6    Oxford, G.S.7    Gereau IV, R.W.8
  • 4
    • 0037104657 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
    • Bhave, G., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., and Gereau, R. W., 4th (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35, 721-731
    • (2002) Neuron , vol.35 , pp. 721-731
    • Bhave, G.1    Zhu, W.2    Wang, H.3    Brasier, D.J.4    Oxford, G.S.5    Gereau IV, R.W.6
  • 5
    • 50249119619 scopus 로고    scopus 로고
    • A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1
    • Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N., and Hargreaves, K. M. (2008) A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain 138, 604-616
    • (2008) Pain , vol.138 , pp. 604-616
    • Jeske, N.A.1    Diogenes, A.2    Ruparel, N.B.3    Fehrenbacher, J.C.4    Henry, M.5    Akopian, A.N.6    Hargreaves, K.M.7
  • 6
    • 70350621238 scopus 로고    scopus 로고
    • A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1
    • Jeske, N. A., Patwardhan, A. M., Ruparel, N. B., Akopian, A. N., Shapiro, M. S., and Henry, M. A. (2009) A-kinase anchoring protein 150 controls protein kinase C-mediated phosphorylation and sensitization of TRPV1. Pain 146, 301-307
    • (2009) Pain , vol.146 , pp. 301-307
    • Jeske, N.A.1    Patwardhan, A.M.2    Ruparel, N.B.3    Akopian, A.N.4    Shapiro, M.S.5    Henry, M.A.6
  • 8
    • 48749115596 scopus 로고    scopus 로고
    • Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150
    • Zhang, X., Li, L., and McNaughton, P. A. (2008) Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150. Neuron 59, 450-461
    • (2008) Neuron , vol.59 , pp. 450-461
    • Zhang, X.1    Li, L.2    McNaughton, P.A.3
  • 9
    • 0346118925 scopus 로고    scopus 로고
    • Desensitization of capsaicinactivated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway
    • Mohapatra, D. P., and Nau, C. (2003) Desensitization of capsaicinactivated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. J. Biol. Chem. 278, 50080-50090
    • (2003) J. Biol. Chem. , vol.278 , pp. 50080-50090
    • Mohapatra, D.P.1    Nau, C.2
  • 10
    • 0029965156 scopus 로고    scopus 로고
    • Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
    • Docherty, R. J., Yeats, J. C., Bevan, S., and Boddeke, H. W. (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Arch. 431, 828-837
    • (1996) Pflugers Arch. , vol.431 , pp. 828-837
    • Docherty, R.J.1    Yeats, J.C.2    Bevan, S.3    Boddeke, H.W.4
  • 12
    • 33746621595 scopus 로고    scopus 로고
    • The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin
    • Patwardhan, A. M., Jeske, N. A., Price, T. J., Gamper, N., Akopian, A. N., and Hargreaves, K. M. (2006) The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin. Proc. Natl. Acad. Sci. U.S.A. 103, 11393-11398
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 11393-11398
    • Patwardhan, A.M.1    Jeske, N.A.2    Price, T.J.3    Gamper, N.4    Akopian, A.N.5    Hargreaves, K.M.6
  • 13
    • 34250190946 scopus 로고    scopus 로고
    • The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
    • Lishko, P. V., Procko, E., Jin, X., Phelps, C. B., and Gaudet, R. (2007) The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron 54, 905-918
    • (2007) Neuron , vol.54 , pp. 905-918
    • Lishko, P.V.1    Procko, E.2    Jin, X.3    Phelps, C.B.4    Gaudet, R.5
  • 18
    • 0035852697 scopus 로고    scopus 로고
    • β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
    • Kohout, T. A., Lin, F. S., Perry, S. J., Conner, D. A., and Lefkowitz, R. J. (2001) β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc. Natl. Acad. Sci. U.S.A. 98, 1601-1606
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 1601-1606
    • Kohout, T.A.1    Lin, F.S.2    Perry, S.J.3    Conner, D.A.4    Lefkowitz, R.J.5
  • 19
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G-protein-coupled receptor regulation
    • Krupnick, J. G., and Benovic, J. L. (1998) The role of receptor kinases and arrestins in G-protein-coupled receptor regulation. Annu. Rev. Pharmacol. Toxicol. 38, 289-319
    • (1998) Annu. Rev. Pharmacol. Toxicol. , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 20
    • 0030664060 scopus 로고    scopus 로고
    • Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity
    • Gurevich, V. V., Pals-Rylaarsdam, R., Benovic, J. L., Hosey, M. M., and Onorato, J. J. (1997) Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity. J. Biol. Chem. 272, 28849-28852
    • (1997) J. Biol. Chem. , vol.272 , pp. 28849-28852
    • Gurevich, V.V.1    Pals-Rylaarsdam, R.2    Benovic, J.L.3    Hosey, M.M.4    Onorato, J.J.5
  • 21
    • 2542423686 scopus 로고    scopus 로고
    • Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7
    • Kohout, T. A., Nicholas, S. L., Perry, S. J., Reinhart, G., Junger, S., and Struthers, R. S. (2004) Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7. J. Biol. Chem. 279, 23214-23222
    • (2004) J. Biol. Chem. , vol.279 , pp. 23214-23222
    • Kohout, T.A.1    Nicholas, S.L.2    Perry, S.J.3    Reinhart, G.4    Junger, S.5    Struthers, R.S.6
  • 23
    • 33746012381 scopus 로고    scopus 로고
    • 2-adrenergic receptor revealed by fluorescence resonance energy transfer
    • 2-adrenergic receptor revealed by fluorescence resonance energy transfer. J. Biol. Chem. 281, 20577-20588
    • (2006) J. Biol. Chem. , vol.281 , pp. 20577-20588
    • Violin, J.D.1    Ren, X.R.2    Lefkowitz, R.J.3
  • 24
    • 14244262888 scopus 로고    scopus 로고
    • Phosphorylation-independent β-arrestin translocation and internalization of leukotriene B4 receptors
    • Jala, V. R., Shao, W. H., and Haribabu, B. (2005) Phosphorylation- independent β-arrestin translocation and internalization of leukotriene B4 receptors. J. Biol. Chem. 280, 4880-4887
    • (2005) J. Biol. Chem. , vol.280 , pp. 4880-4887
    • Jala, V.R.1    Shao, W.H.2    Haribabu, B.3
  • 25
    • 0037423307 scopus 로고    scopus 로고
    • N-Formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity
    • Key, T. A., Foutz, T. D., Gurevich, V. V., Sklar, L. A., and Prossnitz, E. R. (2003)N-Formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity. J. Biol. Chem. 278, 4041-4047
    • (2003) J. Biol. Chem. , vol.278 , pp. 4041-4047
    • Key, T.A.1    Foutz, T.D.2    Gurevich, V.V.3    Sklar, L.A.4    Prossnitz, E.R.5
  • 27
    • 0033610892 scopus 로고    scopus 로고
    • β-Arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor i receptor
    • Lin, F. T., Daaka, Y., and Lefkowitz, R. J. (1998) β-Arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J. Biol. Chem. 273, 31640-31643
    • (1998) J. Biol. Chem. , vol.273 , pp. 31640-31643
    • Lin, F.T.1    Daaka, Y.2    Lefkowitz, R.J.3
  • 28
    • 77956919285 scopus 로고    scopus 로고
    • Arresting a transient receptor potential (TRP) channel. β-Arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4
    • Shukla, A. K., Kim, J., Ahn, S., Xiao, K., Shenoy, S. K., Liedtke, W., and Lefkowitz, R. J. (2010) Arresting a transient receptor potential (TRP) channel. β-Arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. J. Biol. Chem. 285, 30115-30125
    • (2010) J. Biol. Chem. , vol.285 , pp. 30115-30125
    • Shukla, A.K.1    Kim, J.2    Ahn, S.3    Xiao, K.4    Shenoy, S.K.5    Liedtke, W.6    Lefkowitz, R.J.7
  • 30
    • 67650245968 scopus 로고    scopus 로고
    • Mdm2 directs the ubiquitination of β-arrestin-sequestered cAMP phosphodiesterase-4D5
    • Li, X., Baillie, G. S., and Houslay, M. D. (2009) Mdm2 directs the ubiquitination of β-arrestin-sequestered cAMP phosphodiesterase-4D5. J. Biol. Chem. 284, 16170-16182
    • (2009) J. Biol. Chem. , vol.284 , pp. 16170-16182
    • Li, X.1    Baillie, G.S.2    Houslay, M.D.3
  • 34
    • 26444511606 scopus 로고    scopus 로고
    • Structure and function of TRPV1
    • Tominaga, M., and Tominaga, T. (2005) Structure and function of TRPV1. Pflugers Arch. 451, 143-150
    • (2005) Pflugers Arch. , vol.451 , pp. 143-150
    • Tominaga, M.1    Tominaga, T.2
  • 36
    • 0034306198 scopus 로고    scopus 로고
    • OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
    • Strotmann, R., Harteneck, C., Nunnenmacher, K., Schultz, G., and Plant, T. D. (2000) OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat. Cell Biol. 2, 695-702
    • (2000) Nat. Cell Biol. , vol.2 , pp. 695-702
    • Strotmann, R.1    Harteneck, C.2    Nunnenmacher, K.3    Schultz, G.4    Plant, T.D.5
  • 38
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 39
    • 58149328528 scopus 로고    scopus 로고
    • Fibronectin stimulates TRPV1 translocation in primary sensory neurons
    • Jeske, N. A., Patwardhan, A. M., Henry, M. A., and Milam, S. B. (2009) Fibronectin stimulates TRPV1 translocation in primary sensory neurons. J. Neurochem. 108, 591-600
    • (2009) J. Neurochem. , vol.108 , pp. 591-600
    • Jeske, N.A.1    Patwardhan, A.M.2    Henry, M.A.3    Milam, S.B.4
  • 41
    • 0025110892 scopus 로고
    • Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes
    • Szallasi, A., and Blumberg, P. M. (1990) Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes. Brain Res. 524, 106-111
    • (1990) Brain Res. , vol.524 , pp. 106-111
    • Szallasi, A.1    Blumberg, P.M.2
  • 42
    • 0025202606 scopus 로고
    • Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor
    • Szallasi, A., and Blumberg, P. M. (1990) Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor. Life Sci. 47, 1399-1408
    • (1990) Life Sci. , vol.47 , pp. 1399-1408
    • Szallasi, A.1    Blumberg, P.M.2
  • 43
    • 33751533776 scopus 로고    scopus 로고
    • New roles for β-arrestins in cell signaling. Not just for seven-transmembrane receptors
    • Lefkowitz, R. J., Rajagopal, K., and Whalen, E. J. (2006) New roles for β-arrestins in cell signaling. Not just for seven-transmembrane receptors. Mol. Cell 24, 643-652
    • (2006) Mol. Cell , vol.24 , pp. 643-652
    • Lefkowitz, R.J.1    Rajagopal, K.2    Whalen, E.J.3
  • 44
    • 0031975838 scopus 로고    scopus 로고
    • Essential role for G-protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
    • Daaka, Y., Luttrell, L. M., Ahn, S., Della Rocca, G. J., Ferguson, S. S., Caron, M. G., and Lefkowitz, R. J. (1998) Essential role for G-protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J. Biol. Chem. 273, 685-688
    • (1998) J. Biol. Chem. , vol.273 , pp. 685-688
    • Daaka, Y.1    Luttrell, L.M.2    Ahn, S.3    Della Rocca, G.J.4    Ferguson, S.S.5    Caron, M.G.6    Lefkowitz, R.J.7
  • 45
    • 0040017536 scopus 로고    scopus 로고
    • Regulation of muscarinic acetylcholine receptor sequestration and function by β-arrestin
    • Vögler, O., Nolte, B., Voss, M., Schmidt, M., Jakobs, K. H., and van Koppen, C. J. (1999) Regulation of muscarinic acetylcholine receptor sequestration and function by β-arrestin. J. Biol. Chem. 274, 12333-12338
    • (1999) J. Biol. Chem. , vol.274 , pp. 12333-12338
    • Vögler, O.1    Nolte, B.2    Voss, M.3    Schmidt, M.4    Jakobs, K.H.5    Van Koppen, C.J.6
  • 46
    • 0036895747 scopus 로고    scopus 로고
    • Differential mechanisms of morphine antinociceptive tolerance revealed in β-arrestin-2 knock-out mice
    • Bohn, L. M., Lefkowitz, R. J., and Caron, M. G. (2002) Differential mechanisms of morphine antinociceptive tolerance revealed in β-arrestin-2 knock-out mice. J. Neurosci. 22, 10494-10500
    • (2002) J. Neurosci. , vol.22 , pp. 10494-10500
    • Bohn, L.M.1    Lefkowitz, R.J.2    Caron, M.G.3
  • 50
    • 0037443097 scopus 로고    scopus 로고
    • PDE4cAMPphosphodiesterases. Modular enzymes that orchestrate signalling cross-talk, desensitization, and compartmentalization
    • Houslay, M. D., and Adams, D. R. (2003) PDE4cAMPphosphodiesterases. Modular enzymes that orchestrate signalling cross-talk, desensitization, and compartmentalization. Biochem. J. 370, 1-18
    • (2003) Biochem. J. , vol.370 , pp. 1-18
    • Houslay, M.D.1    Adams, D.R.2
  • 51
    • 33644753903 scopus 로고    scopus 로고
    • Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes
    • Li, X., Huston, E., Lynch, M. J., Houslay, M. D., and Baillie, G. S. (2006) Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes. Biochem. J. 394, 427-435
    • (2006) Biochem. J. , vol.394 , pp. 427-435
    • Li, X.1    Huston, E.2    Lynch, M.J.3    Houslay, M.D.4    Baillie, G.S.5
  • 52
    • 17144397173 scopus 로고    scopus 로고
    • 2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMPdependent protein kinase
    • 2+- dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMPdependent protein kinase. J. Biol. Chem. 280, 13424-13432
    • (2005) J. Biol. Chem. , vol.280 , pp. 13424-13432
    • Mohapatra, D.P.1    Nau, C.2
  • 53
    • 0038721194 scopus 로고    scopus 로고
    • A tyrosine residue in TM6 of the vanilloid receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents
    • Mohapatra, D. P., Wang, S. Y., Wang, G. K., and Nau, C. (2003) A tyrosine residue in TM6 of the vanilloid receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents. Mol. Cell. Neurosci. 23, 314-324
    • (2003) Mol. Cell. Neurosci. , vol.23 , pp. 314-324
    • Mohapatra, D.P.1    Wang, S.Y.2    Wang, G.K.3    Nau, C.4
  • 55
    • 0034724702 scopus 로고    scopus 로고
    • Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells
    • Mundell, S. J., and Benovic, J. L. (2000) Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells. J. Biol. Chem. 275, 12900-12908
    • (2000) J. Biol. Chem. , vol.275 , pp. 12900-12908
    • Mundell, S.J.1    Benovic, J.L.2
  • 56
    • 70349986967 scopus 로고    scopus 로고
    • Arrestin development. Emerging roles for β-arrestins in developmental signaling pathways
    • Kovacs, J. J., Hara, M. R., Davenport, C. L., Kim, J., and Lefkowitz, R. J. (2009) Arrestin development. Emerging roles for β-arrestins in developmental signaling pathways. Dev. Cell 17, 443-458
    • (2009) Dev. Cell , vol.17 , pp. 443-458
    • Kovacs, J.J.1    Hara, M.R.2    Davenport, C.L.3    Kim, J.4    Lefkowitz, R.J.5
  • 57
    • 78650854802 scopus 로고    scopus 로고
    • β-Arrestins as regulators of signal termination and transduction. How do they determine what to scaffold?
    • DeFea, K. A. (2011) β-Arrestins as regulators of signal termination and transduction. How do they determine what to scaffold? Cell. Signal. 23, 621-629
    • (2011) Cell. Signal. , vol.23 , pp. 621-629
    • Defea, K.A.1
  • 58
    • 0032584673 scopus 로고    scopus 로고
    • Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene
    • Jin, S. L., Bushnik, T., Lan, L., and Conti, M. (1998) Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene. J. Biol. Chem. 273, 19672-19678
    • (1998) J. Biol. Chem. , vol.273 , pp. 19672-19678
    • Jin, S.L.1    Bushnik, T.2    Lan, L.3    Conti, M.4
  • 59
    • 77956807049 scopus 로고    scopus 로고
    • Modulation of single-channel properties of TRPV1 by phosphorylation
    • Studer, M., and McNaughton, P. A. (2010) Modulation of single-channel properties of TRPV1 by phosphorylation. J. Physiol. 588, 3743-3756
    • (2010) J. Physiol. , vol.588 , pp. 3743-3756
    • Studer, M.1    McNaughton, P.A.2
  • 60
    • 1642394771 scopus 로고    scopus 로고
    • Activation of protein kinase C reverses capsaicininduced calcium-dependent desensitization of TRPV1 ion channels
    • Mandadi, S., Numazaki, M., Tominaga, M., Bhat, M. B., Armati, P. J., and Roufogalis, B. D. (2004) Activation of protein kinase C reverses capsaicininduced calcium-dependent desensitization of TRPV1 ion channels. Cell Calcium 35, 471-478
    • (2004) Cell Calcium , vol.35 , pp. 471-478
    • Mandadi, S.1    Numazaki, M.2    Tominaga, M.3    Bhat, M.B.4    Armati, P.J.5    Roufogalis, B.D.6


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