메뉴 건너뛰기




Volumn 31, Issue C, 1997, Pages 263-277

21 G-protein-coupled receptors and their regulation: Activation of the MAP kinase singnaling pathway by G-protein-coupled receptors

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOPROTEIN; PLASMA PROTEIN; PLATELET PROTEIN P47; PROTEIN KINASE (CALCIUM,CALMODULIN); RAS PROTEIN; TYROSINE;

EID: 0030626935     PISSN: 10407952     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1040-7952(97)80024-9     Document Type: Article
Times cited : (97)

References (83)
  • 1
    • 0027422247 scopus 로고
    • The pathway to signal achievement
    • Egan, S, Weinberg, RA, The pathway to signal achievement. Nature 365 (1993), 781-783.
    • (1993) Nature , vol.365 , pp. 781-783
    • Egan, S.1    Weinberg, R.A.2
  • 2
    • 0027138356 scopus 로고
    • ras in receptor tyrosine kinase signaling
    • ras in receptor tyrosine kinase signaling. Crit Rev Oncogen 4 (1993), 615-661.
    • (1993) Crit Rev Oncogen , vol.4 , pp. 615-661
    • Medema, R.H.1    Bos, J.L.2
  • 3
    • 0026484261 scopus 로고
    • SH2 and SH3 domains: from structure to function
    • Pawson, T, Gish, GD, SH2 and SH3 domains: from structure to function. Cell 71 (1992), 359-362.
    • (1992) Cell , vol.71 , pp. 359-362
    • Pawson, T.1    Gish, G.D.2
  • 4
  • 5
    • 0026729382 scopus 로고
    • The SH2 and SH3 domain-containing protein Grb2 links receptor tyrosine kinases to Ras signaling
    • Lowenstein, EJ, Daly, RJ, Batzer, AG, et al. The SH2 and SH3 domain-containing protein Grb2 links receptor tyrosine kinases to Ras signaling. Cell 70 (1992), 431-442.
    • (1992) Cell , vol.70 , pp. 431-442
    • Lowenstein, E.J.1    Daly, R.J.2    Batzer, A.G.3
  • 6
    • 0027294981 scopus 로고
    • The SH2 and SH3 domains of mammalian Grb2, couple the EGF receptor to the Ras activator mSos1
    • Rozakis-Adcock, M, Fernley, R, Wade, J, Pawson, T, Bowtell, D, The SH2 and SH3 domains of mammalian Grb2, couple the EGF receptor to the Ras activator mSos1. Nature 363 (1993), 83-85.
    • (1993) Nature , vol.363 , pp. 83-85
    • Rozakis-Adcock, M.1    Fernley, R.2    Wade, J.3    Pawson, T.4    Bowtell, D.5
  • 8
    • 0027428530 scopus 로고
    • Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation
    • Haung, W, Alessandrini, A, Crews, CM, Erikson, RL, Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation. Proc Natl Acad Sci USA 90 (1993), 10947-10951.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10947-10951
    • Haung, W.1    Alessandrini, A.2    Crews, C.M.3    Erikson, R.L.4
  • 9
    • 0027337519 scopus 로고
    • Complexes of Ras-GTP with Raf1 and mitogen-activated protein kinase kinase
    • Moodie, SA, Willumsen, BM, Weber, MJ, Wolfman, A, Complexes of Ras-GTP with Raf1 and mitogen-activated protein kinase kinase. Science 260 (1993), 1658-1661.
    • (1993) Science , vol.260 , pp. 1658-1661
    • Moodie, S.A.1    Willumsen, B.M.2    Weber, M.J.3    Wolfman, A.4
  • 10
    • 0027014912 scopus 로고
    • The mitogen-activated protein kinase activator
    • Ahn, NG, Seger, R, Krebs, EG, The mitogen-activated protein kinase activator. Curr Opin Cell Biol 4 (1992), 992-999.
    • (1992) Curr Opin Cell Biol , vol.4 , pp. 992-999
    • Ahn, N.G.1    Seger, R.2    Krebs, E.G.3
  • 11
    • 0027233448 scopus 로고
    • Signal transduction via the MAP kinases: proceed at your own RSK
    • Blenis, J, Signal transduction via the MAP kinases: proceed at your own RSK. Proc Natl Acad Sci USA 90 (1993), 5889-5892.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5889-5892
    • Blenis, J.1
  • 15
    • 0028982948 scopus 로고
    • Distinct pathways of Gi-and Gq-mediated mitogen-activated protein kinase activation
    • Hawes, BE, van Biesen, T, Koch, WJ, Luttrell, LM, Lefkowitz, RJ, Distinct pathways of Gi-and Gq-mediated mitogen-activated protein kinase activation. J Biol Chem 270 (1995), 17148-17153.
    • (1995) J Biol Chem , vol.270 , pp. 17148-17153
    • Hawes, B.E.1    van Biesen, T.2    Koch, W.J.3    Luttrell, L.M.4    Lefkowitz, R.J.5
  • 16
    • 0028176297 scopus 로고
    • cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure, M, Voyno-Yasenetskaya, TA, Bourne, HR, cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem 269 (1994), 7851-7854.
    • (1994) J Biol Chem , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 17
    • 0028145447 scopus 로고
    • Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation. Evidence for a protein kinase C-independent pathway
    • Crespo, P, Xu, N, Daniotti, JL, Troppmair, J, Rapp, UR, Gutkind, JS, Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation. Evidence for a protein kinase C-independent pathway. J Biol Chem 269 (1994), 21103-21109.
    • (1994) J Biol Chem , vol.269 , pp. 21103-21109
    • Crespo, P.1    Xu, N.2    Daniotti, J.L.3    Troppmair, J.4    Rapp, U.R.5    Gutkind, J.S.6
  • 18
    • 0027240231 scopus 로고
    • Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic M2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
    • Winitz, S, Russell, M, Quian, N-X, Gardner, A, Dwyer, L, Johnson, GL, Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic M2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J Biol Chem 268 (1993), 19196-19199.
    • (1993) J Biol Chem , vol.268 , pp. 19196-19199
    • Winitz, S.1    Russell, M.2    Quian, N.-X.3    Gardner, A.4    Dwyer, L.5    Johnson, G.L.6
  • 19
    • 0027982408 scopus 로고
    • Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways
    • Ohmichi, M, Sawada, T, Kanda, Y, et al. Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways. J Biol Chem 269 (1994), 3783-3788.
    • (1994) J Biol Chem , vol.269 , pp. 3783-3788
    • Ohmichi, M.1    Sawada, T.2    Kanda, Y.3
  • 20
    • 0029074408 scopus 로고
    • Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells
    • Linseman, DA, Benjamin, CW, Jones, DA, Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J Biol Chem 270 (1995), 12563-12568.
    • (1995) J Biol Chem , vol.270 , pp. 12563-12568
    • Linseman, D.A.1    Benjamin, C.W.2    Jones, D.A.3
  • 22
    • 0029032202 scopus 로고
    • Lysophosphatidic acid, a multifunctional phospholipid messenger
    • Moolenaar, WH, Lysophosphatidic acid, a multifunctional phospholipid messenger. J Biol Chem 270 (1995), 12949-12952.
    • (1995) J Biol Chem , vol.270 , pp. 12949-12952
    • Moolenaar, W.H.1
  • 25
    • 0028091046 scopus 로고
    • Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts
    • Hordijk, PL, Verlaan, I, van Corven, EJ, Moolenaar, WH, Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. J Biol Chem 269 (1994), 645-651.
    • (1994) J Biol Chem , vol.269 , pp. 645-651
    • Hordijk, P.L.1    Verlaan, I.2    van Corven, E.J.3    Moolenaar, W.H.4
  • 26
    • 0029095717 scopus 로고
    • Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor
    • Buhl, AM, Osawa, S, Johnson, GL, Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor. J Biol Chem 270 (1995), 19828-19832.
    • (1995) J Biol Chem , vol.270 , pp. 19828-19832
    • Buhl, A.M.1    Osawa, S.2    Johnson, G.L.3
  • 28
    • 0027171138 scopus 로고
    • Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins
    • Gardner, AM, Vaillancourt, RR, Johnson, GL, Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. J Biol Chem 268 (1993), 17896-17901.
    • (1993) J Biol Chem , vol.268 , pp. 17896-17901
    • Gardner, A.M.1    Vaillancourt, R.R.2    Johnson, G.L.3
  • 29
    • 0027249389 scopus 로고
    • A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells
    • LaMorte, VJ, Kennedy, ED, Collins, LR, et al. A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells. J Biol Chem 268 (1993), 19411-19415.
    • (1993) J Biol Chem , vol.268 , pp. 19411-19415
    • LaMorte, V.J.1    Kennedy, E.D.2    Collins, L.R.3
  • 31
    • 0026667731 scopus 로고
    • Chemoattractant-induced tyrosine phosphorylation and activation of microtubule-associated protein kinase in human neutrophils
    • Grinstein, S, Furuya, W, Chemoattractant-induced tyrosine phosphorylation and activation of microtubule-associated protein kinase in human neutrophils. J Biol Chem 267 (1992), 18122-18125.
    • (1992) J Biol Chem , vol.267 , pp. 18122-18125
    • Grinstein, S.1    Furuya, W.2
  • 32
    • 0027930914 scopus 로고
    • FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase
    • Worthen, GS, Avdi, N, Buhl, AM, Suzuki, N, Johnson, GL, FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase. J Clin Invest 94 (1994), 815-823.
    • (1994) J Clin Invest , vol.94 , pp. 815-823
    • Worthen, G.S.1    Avdi, N.2    Buhl, A.M.3    Suzuki, N.4    Johnson, G.L.5
  • 33
    • 0029164908 scopus 로고
    • Differential effects of cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1
    • Faure, M, Bourne, HR, Differential effects of cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1. Mol Biol Cell 6 (1995), 1025-1035.
    • (1995) Mol Biol Cell , vol.6 , pp. 1025-1035
    • Faure, M.1    Bourne, H.R.2
  • 34
    • 0029083694 scopus 로고
    • Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC-12 cells
    • Erhardt, P, Troppmair, J, Rapp, UR, Cooper, GM, Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC-12 cells. Mol Cell Biol 15 (1995), 5524-5530.
    • (1995) Mol Cell Biol , vol.15 , pp. 5524-5530
    • Erhardt, P.1    Troppmair, J.2    Rapp, U.R.3    Cooper, G.M.4
  • 35
    • 0027716596 scopus 로고
    • Inhibition by cAMP of Ras-dependent activation of Ras
    • Cook, SJ, McCormick, F, Inhibition by cAMP of Ras-dependent activation of Ras. Science 262 (1993), 1069-1072.
    • (1993) Science , vol.262 , pp. 1069-1072
    • Cook, S.J.1    McCormick, F.2
  • 37
    • 0027326410 scopus 로고
    • Protein kinase C activates Raf-1 by direct phosphorylation
    • Kolch, W, Heidecker, G, Kochs, G, et al. Protein kinase C activates Raf-1 by direct phosphorylation. Nature 364 (1993), 249-252.
    • (1993) Nature , vol.364 , pp. 249-252
    • Kolch, W.1    Heidecker, G.2    Kochs, G.3
  • 38
    • 0023715225 scopus 로고
    • Inhibition of NIH3T3 cell proliferation by a mutant Ras protein with preferential affinity for GDP
    • Feig, LA, Cooper, GM, Inhibition of NIH3T3 cell proliferation by a mutant Ras protein with preferential affinity for GDP. Mol Cell Biol 8 (1988), 3235-3243.
    • (1988) Mol Cell Biol , vol.8 , pp. 3235-3243
    • Feig, L.A.1    Cooper, G.M.2
  • 39
    • 0024428410 scopus 로고
    • Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins
    • van Corven, EJ, Groenink, A, Jalink, K, Eicholtz, T, Moolenaar, WH, Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 59 (1989), 45-54.
    • (1989) Cell , vol.59 , pp. 45-54
    • van Corven, E.J.1    Groenink, A.2    Jalink, K.3    Eicholtz, T.4    Moolenaar, W.H.5
  • 41
    • 0016432831 scopus 로고
    • Mitogenic activity of blood components. I. Thrombin and prothrombin
    • Chen, LB, Buchannan, JM, Mitogenic activity of blood components. I. Thrombin and prothrombin. Proc Natl Acad Sci USA 72 (1975), 131-135.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 131-135
    • Chen, L.B.1    Buchannan, J.M.2
  • 42
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu, TK, Hung, D, Wheaton, VI, Coughlin, SR, Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64 (1991), 1057-1062.
    • (1991) Cell , vol.64 , pp. 1057-1062
    • Vu, T.K.1    Hung, D.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 43
    • 0025432805 scopus 로고
    • α2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human α2-adrenergic receptor gene
    • Seuwen, K, Magnaldo, I, Kobilka, BK, et al. α2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human α2-adrenergic receptor gene. Cell Regul 1 (1990), 445-451.
    • (1990) Cell Regul , vol.1 , pp. 445-451
    • Seuwen, K.1    Magnaldo, I.2    Kobilka, B.K.3
  • 44
    • 0027495684 scopus 로고
    • New roles for G protein βγ-dimers in transmembrane signalling
    • Clapham, DE, Neer, EJ, New roles for G protein βγ-dimers in transmembrane signalling. Nature 365 (1993), 159-161.
    • (1993) Nature , vol.365 , pp. 159-161
    • Clapham, D.E.1    Neer, E.J.2
  • 45
    • 0026640629 scopus 로고
    • MAP kinase is constitutively activated in Gip2 and src transformed Rat 1a fibroblasts
    • Gupta, SK, Gallego, C, Johnson, GL, Heasley, LE, MAP kinase is constitutively activated in Gip2 and src transformed Rat 1a fibroblasts. J Biol Chem 267 (1992), 7987-7990.
    • (1992) J Biol Chem , vol.267 , pp. 7987-7990
    • Gupta, S.K.1    Gallego, C.2    Johnson, G.L.3    Heasley, L.E.4
  • 46
    • 0028999856 scopus 로고
    • G protein βγ subunit activates Ras, Raf, and MAP kinase in HEK 293 cells
    • Ito, A, Satoh, T, Kaziro, Y, Itoh, H, G protein βγ subunit activates Ras, Raf, and MAP kinase in HEK 293 cells. FEBS Lett 368 (1995), 183-187.
    • (1995) FEBS Lett , vol.368 , pp. 183-187
    • Ito, A.1    Satoh, T.2    Kaziro, Y.3    Itoh, H.4
  • 47
    • 0026803164 scopus 로고
    • Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors
    • Pitcher, JA, Inglese, JI, Higgins, JB, et al. Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors. Science 257 (1992), 1264-1267.
    • (1992) Science , vol.257 , pp. 1264-1267
    • Pitcher, J.A.1    Inglese, J.I.2    Higgins, J.B.3
  • 48
    • 0027481032 scopus 로고
    • The binding site for the βγ subunits of heterotrimeric G proteins of the β-adrenergic receptor kinase
    • Koch, WJ, Inglese, JI, Stone, WC, Lefkowitz, RJ, The binding site for the βγ subunits of heterotrimeric G proteins of the β-adrenergic receptor kinase. J Biol Chem 268 (1993), 8256-8260.
    • (1993) J Biol Chem , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.I.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 49
    • 0028085776 scopus 로고
    • Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling
    • Koch, WJ, Hawes, BE, Inglese, JI, Luttrell, LM, Lefkowitz, RJ, Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling. J Biol Chem 269 (1994), 6193-6197.
    • (1994) J Biol Chem , vol.269 , pp. 6193-6197
    • Koch, W.J.1    Hawes, B.E.2    Inglese, J.I.3    Luttrell, L.M.4    Lefkowitz, R.J.5
  • 50
    • 0028260220 scopus 로고
    • A functionally active subdomain of the β-adrenergic receptor kinase: an inhibitor of Gβγ-mediated stimulation of type II adenylyl cyclase
    • Inglese, JI, Luttrell, LM, Iniguez-Lluhi, J, Touhara, K, Lefkowitz, RJ, A functionally active subdomain of the β-adrenergic receptor kinase: an inhibitor of Gβγ-mediated stimulation of type II adenylyl cyclase. Proc Natl Acad Sci USA 91 (1994), 3637-3641.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3637-3641
    • Inglese, J.I.1    Luttrell, L.M.2    Iniguez-Lluhi, J.3    Touhara, K.4    Lefkowitz, R.J.5
  • 52
    • 0027463579 scopus 로고
    • Bombesin and epidermal growth factor stimulate the mitogen activated protein kinase pathway through different pathways in Swiss 3T3 cells
    • Page, L, Decker, SJ, Saltiel, AR, Bombesin and epidermal growth factor stimulate the mitogen activated protein kinase pathway through different pathways in Swiss 3T3 cells. Biochem J 289 (1993), 283-287.
    • (1993) Biochem J , vol.289 , pp. 283-287
    • Page, L.1    Decker, S.J.2    Saltiel, A.R.3
  • 53
    • 0027465124 scopus 로고
    • Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells
    • Molloy, CJ, Taylor, DS, Weber, H, Angiotensin II stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells. J Biol Chem 268 (1993), 7338-7345.
    • (1993) J Biol Chem , vol.268 , pp. 7338-7345
    • Molloy, C.J.1    Taylor, D.S.2    Weber, H.3
  • 54
    • 0028977847 scopus 로고
    • Receptor-tyrosine-kinase-and Gβγ-mediated MAP kinase activation by a common signaling pathway
    • van Biesen, T, Hawes, BE, Luttrell, DK, et al. Receptor-tyrosine-kinase-and Gβγ-mediated MAP kinase activation by a common signaling pathway. Nature 376 (1995), 781-784.
    • (1995) Nature , vol.376 , pp. 781-784
    • van Biesen, T.1    Hawes, B.E.2    Luttrell, D.K.3
  • 55
    • 0028924009 scopus 로고
    • A dominant negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and-independent insulin signaling pathways
    • Sakuae, M, Bowtell, D, Kasuga, M, A dominant negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and-independent insulin signaling pathways. Mol Cell Biol 15 (1995), 379-388.
    • (1995) Mol Cell Biol , vol.15 , pp. 379-388
    • Sakuae, M.1    Bowtell, D.2    Kasuga, M.3
  • 56
    • 0026483357 scopus 로고
    • Function of Ras as a molecular switch in signal transduction
    • Satoh, T, Nakafuku, M, Kaziro, Y, Function of Ras as a molecular switch in signal transduction. J Biol Chem 267 (1992), 24149-24152.
    • (1992) J Biol Chem , vol.267 , pp. 24149-24152
    • Satoh, T.1    Nakafuku, M.2    Kaziro, Y.3
  • 57
    • 0027999621 scopus 로고
    • Activation of Src family kinase activity by the G-protein-coupled thrombin receptor in growth-responsive fibroblasts
    • Chen, Y-H, Pouyssegur, J, Courtneidge, SA, Van Obberghen-Schilling, E, Activation of Src family kinase activity by the G-protein-coupled thrombin receptor in growth-responsive fibroblasts. J Biol Chem 269 (1994), 27372-27377.
    • (1994) J Biol Chem , vol.269 , pp. 27372-27377
    • Chen, Y.-H.1    Pouyssegur, J.2    Courtneidge, S.A.3    Van Obberghen-Schilling, E.4
  • 58
    • 0029148780 scopus 로고
    • G-protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase-Shc adapter protein signaling complexes
    • Ptasznik, A, Traynor-Kaplan, A, Bokoch, GM, G-protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase-Shc adapter protein signaling complexes. J Biol Chem 270 (1995), 19969-19973.
    • (1995) J Biol Chem , vol.270 , pp. 19969-19973
    • Ptasznik, A.1    Traynor-Kaplan, A.2    Bokoch, G.M.3
  • 59
    • 0029154733 scopus 로고
    • 2+-induced regulation of ion channel and MAP kinase functions
    • 2+-induced regulation of ion channel and MAP kinase functions. Nature 376 (1995), 737-745.
    • (1995) Nature , vol.376 , pp. 737-745
    • Lev, S.1    Moreno, H.2    Martinez, R.3
  • 60
    • 0028896344 scopus 로고
    • Activation of Tsk and Btk tyrosine kinases by G protein βγ subunits
    • Langhans-Rajasekaran, SA, Wan, Y, Huang, X-Y, Activation of Tsk and Btk tyrosine kinases by G protein βγ subunits. Proc Natl Acad Sci USA 92 (1995), 8601-8605.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8601-8605
    • Langhans-Rajasekaran, S.A.1    Wan, Y.2    Huang, X.-Y.3
  • 61
    • 0027980301 scopus 로고
    • Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction
    • Cheng, G, Ye, Z-S, Baltimore, D, Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction. Proc Natl Acad Sci USA 91 (1994), 8152-8155.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8152-8155
    • Cheng, G.1    Ye, Z.-S.2    Baltimore, D.3
  • 63
    • 0028933979 scopus 로고
    • The phosphotyrosine phosphatase PTP1D but not PTP1C is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G-protein-coupled receptors
    • Rivard, N, McKenzie, FR, Brondello, J-M, Pouyssegur, J, The phosphotyrosine phosphatase PTP1D but not PTP1C is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G-protein-coupled receptors. J Biol Chem 270 (1995), 11017-11024.
    • (1995) J Biol Chem , vol.270 , pp. 11017-11024
    • Rivard, N.1    McKenzie, F.R.2    Brondello, J.-M.3    Pouyssegur, J.4
  • 64
    • 0029069226 scopus 로고
    • Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein
    • Li, RY, Gaits, F, Ragab, A, Ragab-Thomas, JMF, Chap, H, Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein. EMBO J 14 (1995), 2519-2526.
    • (1995) EMBO J , vol.14 , pp. 2519-2526
    • Li, R.Y.1    Gaits, F.2    Ragab, A.3    Ragab-Thomas, J.M.F.4    Chap, H.5
  • 65
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
    • Ui, M, Okada, T, Hazeki, K, Hazeki, O, Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. TIBS 20 (1995), 303-307.
    • (1995) TIBS , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 67
    • 0028334738 scopus 로고
    • A novel phosphoinositide-3-kinase activity in myeloid-derived cells is activated by G protein βγ subunits
    • Stephens, L, Smrcka, A, Cooke, FT, Jackson, TR, Sternweis, PC, Hawkins, PT, A novel phosphoinositide-3-kinase activity in myeloid-derived cells is activated by G protein βγ subunits. Cell 77 (1994), 83-93.
    • (1994) Cell , vol.77 , pp. 83-93
    • Stephens, L.1    Smrcka, A.2    Cooke, F.T.3    Jackson, T.R.4    Sternweis, P.C.5    Hawkins, P.T.6
  • 68
    • 0028178715 scopus 로고
    • A G-protein βγ-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol
    • Thomason, PA, James, SR, Casey, PJ, Downes, CP, A G-protein βγ-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol. J Biol Chem 269 (1994), 16525-16528.
    • (1994) J Biol Chem , vol.269 , pp. 16525-16528
    • Thomason, P.A.1    James, S.R.2    Casey, P.J.3    Downes, C.P.4
  • 69
    • 0029090212 scopus 로고
    • Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
    • Stoyanov, B, Volinia, S, Hanck, T, et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 269 (1995), 690-693.
    • (1995) Science , vol.269 , pp. 690-693
    • Stoyanov, B.1    Volinia, S.2    Hanck, T.3
  • 70
    • 0028932435 scopus 로고
    • Association of phosphatidylinositol 3-kinase with SHC in chronic myelogenous leukemia cells
    • Harrison-Findik, D, Susa, M, Varticovski, L, Association of phosphatidylinositol 3-kinase with SHC in chronic myelogenous leukemia cells. Oncogene 10 (1995), 1385-1391.
    • (1995) Oncogene , vol.10 , pp. 1385-1391
    • Harrison-Findik, D.1    Susa, M.2    Varticovski, L.3
  • 71
    • 0029046983 scopus 로고
    • Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase
    • Wang, J, Auger, KR, Jarvis, L, Shi, Y, Roberts, TM, Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase. J Biol Chem 270 (1995), 12774-12780.
    • (1995) J Biol Chem , vol.270 , pp. 12774-12780
    • Wang, J.1    Auger, K.R.2    Jarvis, L.3    Shi, Y.4    Roberts, T.M.5
  • 73
    • 0028021882 scopus 로고
    • Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
    • Harlan, JE, Hajduk, PJ, Yoon, HS, Fesik, SW, Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature, 1994, 168-170.
    • (1994) Nature , pp. 168-170
    • Harlan, J.E.1    Hajduk, P.J.2    Yoon, H.S.3    Fesik, S.W.4
  • 75
    • 0028173394 scopus 로고
    • Binding of βγ subunits of heterotrimeric G proteins to the pleckstrin homology domain of Bruton tyrosine kinase
    • Tsukada, S, Simon, MI, Witte, ON, Katz, A, Binding of βγ subunits of heterotrimeric G proteins to the pleckstrin homology domain of Bruton tyrosine kinase. Proc Natl Acad Sci USA 91 (1994), 11256-11260.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11256-11260
    • Tsukada, S.1    Simon, M.I.2    Witte, O.N.3    Katz, A.4
  • 76
    • 0029086568 scopus 로고
    • Structural studies on the PH domains of Dbl, Sos1, IRS-1, and βARK1 and their differential binding to Gβγ subunits
    • Mahadevan, D, Thanki, N, Singh, J, et al. Structural studies on the PH domains of Dbl, Sos1, IRS-1, and βARK1 and their differential binding to Gβγ subunits. Biochemistry 34 (1995), 9111-9117.
    • (1995) Biochemistry , vol.34 , pp. 9111-9117
    • Mahadevan, D.1    Thanki, N.2    Singh, J.3
  • 77
    • 0028891875 scopus 로고
    • Mutational analysis of the pleckstrin homology domain of the β-adrenergic receptor kinase
    • Touhara, K, Koch, WJ, Hawes, BE, Lefkowitz, RJ, Mutational analysis of the pleckstrin homology domain of the β-adrenergic receptor kinase. J Biol Chem 270 (1995), 17000-17005.
    • (1995) J Biol Chem , vol.270 , pp. 17000-17005
    • Touhara, K.1    Koch, W.J.2    Hawes, B.E.3    Lefkowitz, R.J.4
  • 78
    • 0029020217 scopus 로고
    • The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling
    • Myers, MG Jr, Grammer, TC, Brooks, J, et al. The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling. J Biol Chem 270 (1995), 11715-11718.
    • (1995) J Biol Chem , vol.270 , pp. 11715-11718
    • Myers, M.G.1    Grammer, T.C.2    Brooks, J.3
  • 79
    • 0029029153 scopus 로고
    • Functional roles for the pleckstrin and DbI homology regions in the Ras exchange factor son-of sevenless
    • McCollam, L, Bonfini, L, Karlovich, CA, et al. Functional roles for the pleckstrin and DbI homology regions in the Ras exchange factor son-of sevenless. J Biol Chem 270 (1995), 15954-15957.
    • (1995) J Biol Chem , vol.270 , pp. 15954-15957
    • McCollam, L.1    Bonfini, L.2    Karlovich, C.A.3
  • 80
    • 0029039613 scopus 로고
    • Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with Gβγ subunits and lipid
    • Pitcher, JA, Touhara, K, Payne, ES, Lefkowitz, RJ, Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with Gβγ subunits and lipid. J Biol Chem 270 (1995), 11707-11710.
    • (1995) J Biol Chem , vol.270 , pp. 11707-11710
    • Pitcher, J.A.1    Touhara, K.2    Payne, E.S.3    Lefkowitz, R.J.4
  • 81
    • 0029065981 scopus 로고
    • Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling
    • Luttrell, LM, Hawes, BE, Touhara, K, van Biesen, T, Koch, WJ, Lefkowitz, RJ, Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling. J Biol Chem 270 (1995), 12984-12989.
    • (1995) J Biol Chem , vol.270 , pp. 12984-12989
    • Luttrell, L.M.1    Hawes, B.E.2    Touhara, K.3    van Biesen, T.4    Koch, W.J.5    Lefkowitz, R.J.6
  • 82
    • 0026757550 scopus 로고
    • Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation
    • Yatomi, Y, Hazaki, O, Kume, S, Ui, M, Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation. Biochem J 285 (1992), 745-751.
    • (1992) Biochem J , vol.285 , pp. 745-751
    • Yatomi, Y.1    Hazaki, O.2    Kume, S.3    Ui, M.4
  • 83
    • 0029084949 scopus 로고
    • Phosphatidylinositol-(3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets
    • Zhang, J, Falck, JR, Reddy, KK, Abrams, CS, Zhao, W, Rittenhouse, SE, Phosphatidylinositol-(3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets. J Biol Chem 270 (1995), 22804-22810.
    • (1995) J Biol Chem , vol.270 , pp. 22804-22810
    • Zhang, J.1    Falck, J.R.2    Reddy, K.K.3    Abrams, C.S.4    Zhao, W.5    Rittenhouse, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.