Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways

Journal of Biological Chemistry

Volumn 283, Issue 8, 2008, Pages 4778-4786

  Lafont, Jérôme E ^a   Talma, Sonia ^a   Hopfgarten, Christine ^a   Murphy, Christopher L ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CELL CULTURE; GENES; LIGAMENTS; MAINTENANCE; NUCLEIC ACIDS; RNA;

ARTICULAR CARTILAGES; BENEFICIAL EFFECTS; CARTILAGE REPAIRS; CHONDROCYTE; CHONDROCYTES; DIFFERENTIATED CELLS; HUMAN ARTICULAR CHONDROCYTES; HUMAN CARTILAGES; MECHANICAL INTEGRITIES; REGULATED GENES; RNA INTERFERENCES;

CARTILAGE;

HYPOXIA INDUCIBLE FACTOR 2ALPHA; MEMBRANE PROTEIN; OSTEOGENIN; PROTEIN CHM1; PROTEIN MIG6; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BONE MORPHOGENETIC PROTEIN; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIGH MOBILITY GROUP PROTEIN; INHIBIN; INHIBIN BETA A SUBUNIT; SIGNAL PEPTIDE; SOX-9 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR;

ADOLESCENT; ARTICLE; CELL DIFFERENTIATION; CELL HYPOXIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ADULT; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; METABOLISM; MIDDLE AGED; PHYSIOLOGY; UPREGULATION;

ADOLESCENT; ADULT; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MORPHOGENETIC PROTEINS; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CELL HYPOXIA; CELLS, CULTURED; CHILD; CHONDROCYTES; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; HIGH MOBILITY GROUP PROTEINS; HUMANS; INHIBIN-BETA SUBUNITS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 41949100321     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707729200     Document Type: Article

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