Multimodal neuroprotection induced by PACAP38 in Oxygen-glucose deprivation and middle cerebral artery occlusion stroke models

Journal of Molecular Neuroscience

Volumn 48, Issue 3, 2012, Pages 526-540

  Lazarovici, Philip ^a   Cohen, Gadi ^a   Arien Zakay, Hadar ^a   Chen, Jieli ^b   Zhang, Chunling ^b   Chopp, Michael ^b   Jiang, Hao ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HENRY FORD HOSPITAL   (United States)

Author keywords

Akt; Apoptosis; BDNF; Erk1 2; Neuroprotection; NgR; P75; PACAP; Stroke; TrkB

Indexed keywords

BETA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; GLUCOSE; MICROTUBULE ASSOCIATED PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE GROWTH FACTOR RECEPTOR; NEURITE PROMOTING FACTOR; NEUROMODULIN; NEUROPEPTIDE; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE 38; PROCASPASE 3; PROTEIN BAX; PROTEIN KINASE B; PROTEIN NOGO; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TROPOMYOSIN; TROPOMYOSIN RELATED KINASE RECEPTOR TYPE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN REGION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL GROWTH; NEUROPROTECTION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; REOXYGENATION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION; GLUCOSE; HYPOXIA-ISCHEMIA, BRAIN; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRAVENOUS; MALE; NERVE TISSUE PROTEINS; NEURITES; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84868213729     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9818-1     Document Type: Article

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