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Volumn 216, Issue 1, 2009, Pages 83-94

Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors

Author keywords

Cord blood progenitors; FGF 2; Free radicals; Neuroprotection; NGF; Oxygen glucose deprivation; PC12 cells; VEGF

Indexed keywords

ANTIOXIDANT; CASPASE 3; FIBROBLAST GROWTH FACTOR; FREE RADICAL; K 252A; LACTATE DEHYDROGENASE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE A; VASCULOTROPIN;

EID: 59949089198     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.11.006     Document Type: Article
Times cited : (71)

References (68)
  • 1
    • 0037059430 scopus 로고    scopus 로고
    • Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells
    • Abu-Raya S., Tabakman R., Blaugrund E., Trembovler V., and Lazarovici P. Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells. Eur. J. Pharmacol. 434 (2002) 109-116
    • (2002) Eur. J. Pharmacol. , vol.434 , pp. 109-116
    • Abu-Raya, S.1    Tabakman, R.2    Blaugrund, E.3    Trembovler, V.4    Lazarovici, P.5
  • 2
    • 57449101862 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment
    • Alexanian A.R., Maiman D.J., Kurpad S.N., and Gennarelli T.A. In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment. Stem Cells Dev. 17 (2008) 1123-1130
    • (2008) Stem Cells Dev. , vol.17 , pp. 1123-1130
    • Alexanian, A.R.1    Maiman, D.J.2    Kurpad, S.N.3    Gennarelli, T.A.4
  • 3
    • 0036939722 scopus 로고    scopus 로고
    • Fibroblast growth factors and neuroprotection
    • Alzheimer C., and Werner S. Fibroblast growth factors and neuroprotection. Adv. Exp. Med. Biol. 513 (2002) 335-351
    • (2002) Adv. Exp. Med. Biol. , vol.513 , pp. 335-351
    • Alzheimer, C.1    Werner, S.2
  • 4
    • 0036199880 scopus 로고    scopus 로고
    • Neuropathological and behavioral consequences of adeno-associated viral vector-mediated continuous intrastriatal neurotrophin delivery in a focal ischemia model in rats
    • Andsberg G., Kokaia Z., Klein R.L., Muzyczka N., Lindvall O., and Mandel R.J. Neuropathological and behavioral consequences of adeno-associated viral vector-mediated continuous intrastriatal neurotrophin delivery in a focal ischemia model in rats. Neurobiol. Dis. 9 (2002) 187-204
    • (2002) Neurobiol. Dis. , vol.9 , pp. 187-204
    • Andsberg, G.1    Kokaia, Z.2    Klein, R.L.3    Muzyczka, N.4    Lindvall, O.5    Mandel, R.J.6
  • 5
    • 35348893146 scopus 로고    scopus 로고
    • Neuronal conditioning medium and nerve growth factor induce neuronal differentiation of collagen-adherent progenitors derived from human umbilical cord blood
    • Arien-Zakay H., Nagler A., Galski H., and Lazarovici P. Neuronal conditioning medium and nerve growth factor induce neuronal differentiation of collagen-adherent progenitors derived from human umbilical cord blood. J. Mol. Neurosci. 32 (2007) 179-191
    • (2007) J. Mol. Neurosci. , vol.32 , pp. 179-191
    • Arien-Zakay, H.1    Nagler, A.2    Galski, H.3    Lazarovici, P.4
  • 6
    • 0038452619 scopus 로고    scopus 로고
    • Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways
    • Barnabé-Heider F., and Miller F.D. Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. J. Neurosci. 23 (2003) 5149-5160
    • (2003) J. Neurosci. , vol.23 , pp. 5149-5160
    • Barnabé-Heider, F.1    Miller, F.D.2
  • 7
    • 0027369394 scopus 로고
    • Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis
    • Boniece I.R., and Wagner J.A. Growth factors protect PC12 cells against ischemia by a mechanism that is independent of PKA, PKC, and protein synthesis. J. Neurosci. 13 (1993) 4220-4228
    • (1993) J. Neurosci. , vol.13 , pp. 4220-4228
    • Boniece, I.R.1    Wagner, J.A.2
  • 8
    • 33646784703 scopus 로고    scopus 로고
    • Neuronal differentiation of human umbilical cord blood neural stem-like cell line
    • Buzańska L., Jurga M., and Domańska-Janik K. Neuronal differentiation of human umbilical cord blood neural stem-like cell line. Neurodegener. Dis. 3 (2006) 19-26
    • (2006) Neurodegener. Dis. , vol.3 , pp. 19-26
    • Buzańska, L.1    Jurga, M.2    Domańska-Janik, K.3
  • 9
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J., Sanberg P.R., Li Y., Wang L., Lu M., Willing A.E., Sanchez-Ramos J., and Chopp M. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 32 (2001) 2682-2688
    • (2001) Stroke , vol.32 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6    Sanchez-Ramos, J.7    Chopp, M.8
  • 12
    • 84934436790 scopus 로고    scopus 로고
    • Transplantation of bone marrow stromal cells for treatment of central nervous system diseases
    • Chopp M., and Li Y. Transplantation of bone marrow stromal cells for treatment of central nervous system diseases. Adv. Exp. Med. Biol. 585 (2006) 49-64
    • (2006) Adv. Exp. Med. Biol. , vol.585 , pp. 49-64
    • Chopp, M.1    Li, Y.2
  • 13
    • 0026660977 scopus 로고
    • Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways
    • Claffey K.P., Wilkison W.O., and Spiegelman B.M. Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways. J. Biol. Chem. 267 (1992) 16317-16322
    • (1992) J. Biol. Chem. , vol.267 , pp. 16317-16322
    • Claffey, K.P.1    Wilkison, W.O.2    Spiegelman, B.M.3
  • 15
    • 33744981865 scopus 로고    scopus 로고
    • Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation
    • Deleyrolle L., Marchal-Victorion S., Dromard C., Fritz V., Saunier M., Sabourin J.C., Tran Van Ba C., Privat A., and Hugnot J.P. Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation. Stem Cells 24 (2006) 748-762
    • (2006) Stem Cells , vol.24 , pp. 748-762
    • Deleyrolle, L.1    Marchal-Victorion, S.2    Dromard, C.3    Fritz, V.4    Saunier, M.5    Sabourin, J.C.6    Tran Van Ba, C.7    Privat, A.8    Hugnot, J.P.9
  • 16
    • 0024550673 scopus 로고
    • Regulation of the differentiation of PC12 pheochromocytoma cells
    • Fujita K., Lazarovici P., and Guroff G. Regulation of the differentiation of PC12 pheochromocytoma cells. Environ. Health Perspect. 80 (1989) 127-142
    • (1989) Environ. Health Perspect. , vol.80 , pp. 127-142
    • Fujita, K.1    Lazarovici, P.2    Guroff, G.3
  • 17
    • 34447631168 scopus 로고    scopus 로고
    • Oxyl radicals, redox-sensitive signalling cascades and antioxidants
    • Genestra M. Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Cell Signal. 19 (2007) 1807-1819
    • (2007) Cell Signal. , vol.19 , pp. 1807-1819
    • Genestra, M.1
  • 18
  • 19
    • 13444291515 scopus 로고    scopus 로고
    • Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia
    • Glantz L., Avramovich A., Trembovler V., Gurvitz V., Kohen R., Eidelman L.A., and Shohami E. Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia. Exp. Neurol. 192 (2005) 117-124
    • (2005) Exp. Neurol. , vol.192 , pp. 117-124
    • Glantz, L.1    Avramovich, A.2    Trembovler, V.3    Gurvitz, V.4    Kohen, R.5    Eidelman, L.A.6    Shohami, E.7
  • 20
    • 30744477950 scopus 로고    scopus 로고
    • From angiogenesis to neuropathology
    • Greenberg D.A., and Jin K. From angiogenesis to neuropathology. Nature 438 (2005) 954-959
    • (2005) Nature , vol.438 , pp. 954-959
    • Greenberg, D.A.1    Jin, K.2
  • 21
    • 0031038070 scopus 로고    scopus 로고
    • The multifunctionality of FGF-2 in the adrenal medulla
    • Grothe C., and Meisinger C. The multifunctionality of FGF-2 in the adrenal medulla. Anat. Embryol. (Berl.) 195 (1997) 103-111
    • (1997) Anat. Embryol. (Berl.) , vol.195 , pp. 103-111
    • Grothe, C.1    Meisinger, C.2
  • 22
    • 34748833133 scopus 로고    scopus 로고
    • The potential of cord blood stem cells for use in regenerative medicine
    • Harris D.T., Badowski M., Ahmad N., and Gaballa M.A. The potential of cord blood stem cells for use in regenerative medicine. Expert Opin. Biol. Ther. 7 (2007) 1311-1322
    • (2007) Expert Opin. Biol. Ther. , vol.7 , pp. 1311-1322
    • Harris, D.T.1    Badowski, M.2    Ahmad, N.3    Gaballa, M.A.4
  • 23
    • 42149164834 scopus 로고    scopus 로고
    • Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro
    • Hau S., Reich D.M., Scholz M., Naumann W., Emmrich F., Kamprad M., and Boltze J. Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neurosci. 9 (2008) 1-15
    • (2008) BMC Neurosci. , vol.9 , pp. 1-15
    • Hau, S.1    Reich, D.M.2    Scholz, M.3    Naumann, W.4    Emmrich, F.5    Kamprad, M.6    Boltze, J.7
  • 24
    • 33644684038 scopus 로고    scopus 로고
    • Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in rats
    • Ikeda N., Nonoguchi N., Zhao M.Z., Watanabe T., Kajimoto Y., Furutama D., Kimura F., Dezawa M., Coffin R.S., Otsuki Y., Kuroiwa T., and Miyatake S. Bone marrow stromal cells that enhanced fibroblast growth factor-2 secretion by herpes simplex virus vector improve neurological outcome after transient focal cerebral ischemia in rats. Stroke 36 (2005) 2725-2730
    • (2005) Stroke , vol.36 , pp. 2725-2730
    • Ikeda, N.1    Nonoguchi, N.2    Zhao, M.Z.3    Watanabe, T.4    Kajimoto, Y.5    Furutama, D.6    Kimura, F.7    Dezawa, M.8    Coffin, R.S.9    Otsuki, Y.10    Kuroiwa, T.11    Miyatake, S.12
  • 25
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released
    • Italiano Jr. J.E., Richardson J.L., Patel-Hett S., Battinelli E., Zaslavsky A., Short S., Ryeom S., Folkman J., and Klement G.L. Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released. Blood 111 (2008) 1227-1233
    • (2008) Blood , vol.111 , pp. 1227-1233
    • Italiano Jr., J.E.1    Richardson, J.L.2    Patel-Hett, S.3    Battinelli, E.4    Zaslavsky, A.5    Short, S.6    Ryeom, S.7    Folkman, J.8    Klement, G.L.9
  • 26
    • 0036014123 scopus 로고    scopus 로고
    • A quantitative bioassay for nerve growth factor, using PC12 clones expressing different levels of trkA receptors
    • Katzir I., Shani J., Regev K., Shabashov D., and Lazarovici P. A quantitative bioassay for nerve growth factor, using PC12 clones expressing different levels of trkA receptors. J. Mol. Neurosci. 18 (2002) 251-264
    • (2002) J. Mol. Neurosci. , vol.18 , pp. 251-264
    • Katzir, I.1    Shani, J.2    Regev, K.3    Shabashov, D.4    Lazarovici, P.5
  • 28
    • 35448962920 scopus 로고    scopus 로고
    • Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: evidence for a role in cytochrome c redistribution
    • Kirkland R.A., Saavedra G.M., and Franklin J.L. Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: evidence for a role in cytochrome c redistribution. J. Neurosci. 27 (2007) 11315-11326
    • (2007) J. Neurosci. , vol.27 , pp. 11315-11326
    • Kirkland, R.A.1    Saavedra, G.M.2    Franklin, J.L.3
  • 29
    • 0034654315 scopus 로고    scopus 로고
    • Quantification of the overall reactive oxygen species scavenging capacity of biological fluids and tissues
    • Kohen R., Vellaichamy E., Hrbac J., Gati I., and Tirosh O. Quantification of the overall reactive oxygen species scavenging capacity of biological fluids and tissues. Free Radic. Biol. Med. 28 (2000) 871-879
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 871-879
    • Kohen, R.1    Vellaichamy, E.2    Hrbac, J.3    Gati, I.4    Tirosh, O.5
  • 31
    • 0346791771 scopus 로고    scopus 로고
    • The protein kinase inhibitors K-252a and staurosporine as modifiers of neurotrophin receptor signal transduction
    • Toxin and Signal Transduction. Gutman Y., and Lazarovici P. (Eds), Harwood Academic Pub., Amsterdam
    • Lazarovici P., Matsuda Y., Kaplan D., and Guroff G. The protein kinase inhibitors K-252a and staurosporine as modifiers of neurotrophin receptor signal transduction. In: Gutman Y., and Lazarovici P. (Eds). Toxin and Signal Transduction. Cell. Mol. Mech. Toxin Action (1997), Harwood Academic Pub., Amsterdam 69-94
    • (1997) Cell. Mol. Mech. Toxin Action , pp. 69-94
    • Lazarovici, P.1    Matsuda, Y.2    Kaplan, D.3    Guroff, G.4
  • 32
    • 34447274187 scopus 로고    scopus 로고
    • Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model
    • Lee H.J., Kim K.S., Park I.H., and Kim S.U. Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS ONE 2 (2007) e156
    • (2007) PLoS ONE , vol.2
    • Lee, H.J.1    Kim, K.S.2    Park, I.H.3    Kim, S.U.4
  • 33
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy A.P., Levy N.S., Wegner S., and Goldberg M.A. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem. 270 (1995) 13333-13340
    • (1995) J. Biol. Chem. , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 34
    • 0026599302 scopus 로고
    • Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma
    • Lindvall O., Ernfors P., Bengzon J., Kokaia Z., Smith M.L., Siesjö B.K., and Persson H. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 648-652
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 648-652
    • Lindvall, O.1    Ernfors, P.2    Bengzon, J.3    Kokaia, Z.4    Smith, M.L.5    Siesjö, B.K.6    Persson, H.7
  • 35
    • 31744440551 scopus 로고    scopus 로고
    • Cytokine interactions in mesenchymal stem cells from cord blood
    • Liu C.H., and Hwang S.M. Cytokine interactions in mesenchymal stem cells from cord blood. Cytokine 32 (2005) 270-279
    • (2005) Cytokine , vol.32 , pp. 270-279
    • Liu, C.H.1    Hwang, S.M.2
  • 36
    • 0036268269 scopus 로고    scopus 로고
    • The association between neuronal nitric oxide synthase and neuronal sensitivity in the brain after brain injury
    • Liu P.K., Robertson C.S., and Valadka A. The association between neuronal nitric oxide synthase and neuronal sensitivity in the brain after brain injury. Ann. N.Y. Acad. Sci. 962 (2002) 226-241
    • (2002) Ann. N.Y. Acad. Sci. , vol.962 , pp. 226-241
    • Liu, P.K.1    Robertson, C.S.2    Valadka, A.3
  • 37
    • 0141688316 scopus 로고    scopus 로고
    • Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line
    • Liu Y., Song X.D., Liu W., Zhang T.Y., and Zuo J. Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line. J. Cell. Mol. Med. 7 (2003) 49-56
    • (2003) J. Cell. Mol. Med. , vol.7 , pp. 49-56
    • Liu, Y.1    Song, X.D.2    Liu, W.3    Zhang, T.Y.4    Zuo, J.5
  • 38
    • 45549103779 scopus 로고    scopus 로고
    • Neural differentiation and potential use of stem cells from the human umbilical cord for central nervous system transplantation therapy
    • Low C.B., Liou Y.C., and Tang B.L. Neural differentiation and potential use of stem cells from the human umbilical cord for central nervous system transplantation therapy. J. Neurosci. Res. 86 (2008) 1670-1679
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1670-1679
    • Low, C.B.1    Liou, Y.C.2    Tang, B.L.3
  • 39
    • 0035998729 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury
    • Lu D., Sanberg P.R., Mahmood A., Li Y., Wang L., Sanchez-Ramos J., and Chopp M. Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury. Cell Transplant 11 (2002) 275-281
    • (2002) Cell Transplant , vol.11 , pp. 275-281
    • Lu, D.1    Sanberg, P.R.2    Mahmood, A.3    Li, Y.4    Wang, L.5    Sanchez-Ramos, J.6    Chopp, M.7
  • 40
    • 0035874498 scopus 로고    scopus 로고
    • Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner
    • Majka M., Janowska-Wieczorek A., Ratajczak J., Ehrenman K., Pietrzkowski Z., Kowalska M.A., Gewirtz A.M., Emerson S.G., and Ratajczak M.Z. Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 97 (2001) 3075-3085
    • (2001) Blood , vol.97 , pp. 3075-3085
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3    Ehrenman, K.4    Pietrzkowski, Z.5    Kowalska, M.A.6    Gewirtz, A.M.7    Emerson, S.G.8    Ratajczak, M.Z.9
  • 41
    • 33745684551 scopus 로고    scopus 로고
    • The therapeutic potential of neural stem cells
    • Martino G., and Pluchino S. The therapeutic potential of neural stem cells. Nat. Rev. Neurosci. 7 (2006) 395-406
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 395-406
    • Martino, G.1    Pluchino, S.2
  • 43
    • 0029927145 scopus 로고    scopus 로고
    • In vivo and in vitro effect of glucocorticoids on fibroblast growth factor (FGF)-2 and FGF receptor 1 expression
    • Meisinger C., Zeschnigk C., and Grothe C. In vivo and in vitro effect of glucocorticoids on fibroblast growth factor (FGF)-2 and FGF receptor 1 expression. J. Biol. Chem. 271 (1996) 16520-16525
    • (1996) J. Biol. Chem. , vol.271 , pp. 16520-16525
    • Meisinger, C.1    Zeschnigk, C.2    Grothe, C.3
  • 44
    • 0036869401 scopus 로고    scopus 로고
    • In vitro and in vivo angiogenesis in PC12 pheochromocytoma cells is mediated by vascular endothelial growth factor
    • Middeke M., Hoffmann S., Hassan I., Wunderlich A., Hofbauer L.C., and Zielke A. In vitro and in vivo angiogenesis in PC12 pheochromocytoma cells is mediated by vascular endothelial growth factor. Exp. Clin. Endocrinol. Diabetes 110 (2002) 386-392
    • (2002) Exp. Clin. Endocrinol. Diabetes , vol.110 , pp. 386-392
    • Middeke, M.1    Hoffmann, S.2    Hassan, I.3    Wunderlich, A.4    Hofbauer, L.C.5    Zielke, A.6
  • 45
    • 0032575562 scopus 로고    scopus 로고
    • Nerve growth factor treatment prevents the increase in superoxide produced by epidermal growth factor in PC12 cells
    • Mills E.M., Takeda K., Yu Z.X., Ferrans V., Katagiri Y., Jiang H., Lavigne M.C., Leto T.L., and Guroff G. Nerve growth factor treatment prevents the increase in superoxide produced by epidermal growth factor in PC12 cells. J. Biol. Chem. 273 (1998) 22165-22168
    • (1998) J. Biol. Chem. , vol.273 , pp. 22165-22168
    • Mills, E.M.1    Takeda, K.2    Yu, Z.X.3    Ferrans, V.4    Katagiri, Y.5    Jiang, H.6    Lavigne, M.C.7    Leto, T.L.8    Guroff, G.9
  • 46
    • 0028176038 scopus 로고
    • Free radical scavenging by brain homogenate: implication to free radical damage and antioxidant defense in brain
    • Mori A., Liu J., Wang X., and Kawai M. Free radical scavenging by brain homogenate: implication to free radical damage and antioxidant defense in brain. Neurochem. Int. 24 (1994) 201-207
    • (1994) Neurochem. Int. , vol.24 , pp. 201-207
    • Mori, A.1    Liu, J.2    Wang, X.3    Kawai, M.4
  • 47
    • 47949101704 scopus 로고    scopus 로고
    • Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment
    • Mylotte L.A., Duffy A.M., Murphy M., O'Brien T., Samali A., Barry F., and Szegezdi E. Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment. Stem Cells 26 (2008) 1325-1336
    • (2008) Stem Cells , vol.26 , pp. 1325-1336
    • Mylotte, L.A.1    Duffy, A.M.2    Murphy, M.3    O'Brien, T.4    Samali, A.5    Barry, F.6    Szegezdi, E.7
  • 48
    • 34250307233 scopus 로고    scopus 로고
    • Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro
    • Neuhoff S., Moers J., Rieks M., Grunwald T., Jensen A., Dermietzel R., and Meier C. Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Exp. Hematol. 35 (2007) 1119-1131
    • (2007) Exp. Hematol. , vol.35 , pp. 1119-1131
    • Neuhoff, S.1    Moers, J.2    Rieks, M.3    Grunwald, T.4    Jensen, A.5    Dermietzel, R.6    Meier, C.7
  • 50
    • 26944469063 scopus 로고    scopus 로고
    • Cell therapy for neurological disorders: a comprehensive review
    • Raedt R., and Boon P. Cell therapy for neurological disorders: a comprehensive review. Acta Neurol. Belg. S105 (2005) 158-170
    • (2005) Acta Neurol. Belg. , vol.S105 , pp. 158-170
    • Raedt, R.1    Boon, P.2
  • 51
    • 0037147130 scopus 로고    scopus 로고
    • K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK
    • Roux P.P., Dorval G., Boudreau M., Angers-Loustau A., Morris S.J., Makkerh J., and Barker P.A. K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. J Biol Chem. 277 (2002) 49473-49480
    • (2002) J Biol Chem. , vol.277 , pp. 49473-49480
    • Roux, P.P.1    Dorval, G.2    Boudreau, M.3    Angers-Loustau, A.4    Morris, S.J.5    Makkerh, J.6    Barker, P.A.7
  • 52
    • 0037106213 scopus 로고    scopus 로고
    • Neural cells derived from adult bone marrow and umbilical cord blood
    • Sanchez-Ramos J.R. Neural cells derived from adult bone marrow and umbilical cord blood. J. Neurosci. Res. 69 (2002) 880-893
    • (2002) J. Neurosci. Res. , vol.69 , pp. 880-893
    • Sanchez-Ramos, J.R.1
  • 53
    • 0343627722 scopus 로고    scopus 로고
    • Recombinant thrombomodulin inhibits thrombin-induced vascular endothelial growth factor production in neuronal cells
    • Sarker K.P., Yamahata H., Nakata M., Arisato T., Nakajima T., Kitajima I., and Maruyama I. Recombinant thrombomodulin inhibits thrombin-induced vascular endothelial growth factor production in neuronal cells. Haemostasis 29 (1999) 343-352
    • (1999) Haemostasis , vol.29 , pp. 343-352
    • Sarker, K.P.1    Yamahata, H.2    Nakata, M.3    Arisato, T.4    Nakajima, T.5    Kitajima, I.6    Maruyama, I.7
  • 55
    • 0034941330 scopus 로고    scopus 로고
    • Nerve growth factor signaling, neuroprotection, and neural repair
    • Sofroniew M.V., Howe C.L., and Mobley W.C. Nerve growth factor signaling, neuroprotection, and neural repair. Annu. Rev. Neurosci. 24 (2001) 1217-1281
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 1217-1281
    • Sofroniew, M.V.1    Howe, C.L.2    Mobley, W.C.3
  • 56
    • 0036228917 scopus 로고    scopus 로고
    • Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector
    • Song B.W., Vinters H.V., Wu D., and Pardridge W.M. Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector. J. Pharmacol. Exp. Ther. 301 (2002) 605-610
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 605-610
    • Song, B.W.1    Vinters, H.V.2    Wu, D.3    Pardridge, W.M.4
  • 57
    • 4644234505 scopus 로고    scopus 로고
    • VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
    • Storkebaum E., Lambrechts D., and Carmeliet P. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 26 (2004) 943-954
    • (2004) Bioessays , vol.26 , pp. 943-954
    • Storkebaum, E.1    Lambrechts, D.2    Carmeliet, P.3
  • 58
    • 12244268644 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of neuroprotection by vascular endothelial growth factor
    • Sun F.Y., and Guo X. Molecular and cellular mechanisms of neuroprotection by vascular endothelial growth factor. J. Neurosci. Res. 79 (2005) 180-184
    • (2005) J. Neurosci. Res. , vol.79 , pp. 180-184
    • Sun, F.Y.1    Guo, X.2
  • 59
    • 23844487736 scopus 로고    scopus 로고
    • Voltage-sensitive and ligand-gated channels in differentiating neural stem-like cells derived from the nonhematopoietic fraction of human umbilical cord blood
    • Sun W., Buzanska L., Domanska-Janik K., Salvi R.J., and Stachowiak M.K. Voltage-sensitive and ligand-gated channels in differentiating neural stem-like cells derived from the nonhematopoietic fraction of human umbilical cord blood. Stem Cells 23 (2005) 931-945
    • (2005) Stem Cells , vol.23 , pp. 931-945
    • Sun, W.1    Buzanska, L.2    Domanska-Janik, K.3    Salvi, R.J.4    Stachowiak, M.K.5
  • 60
    • 0037093669 scopus 로고    scopus 로고
    • Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia
    • Tabakman R., Lazarovici P., and Kohen R. Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. J. Neurosci. Res. 68 (2002) 463-469
    • (2002) J. Neurosci. Res. , vol.68 , pp. 463-469
    • Tabakman, R.1    Lazarovici, P.2    Kohen, R.3
  • 61
    • 0742270427 scopus 로고    scopus 로고
    • Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia
    • Tabakman R., Jiang H., Levine R.A., Kohen R., and Lazarovici P. Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. J. Neurosci. Res. 75 (2004) 499-507
    • (2004) J. Neurosci. Res. , vol.75 , pp. 499-507
    • Tabakman, R.1    Jiang, H.2    Levine, R.A.3    Kohen, R.4    Lazarovici, P.5
  • 62
    • 2942514365 scopus 로고    scopus 로고
    • Nerve growth factor pretreatment attenuates oxygen and glucose deprivation-induced c-Jun amino-terminal kinase 1 and stress-activated kinases p38alpha and p38beta activation and confers neuroprotection in the pheochromocytoma PC12 model
    • Tabakman R., Jiang H., Schaefer E., Levine R.A., and Lazarovici P. Nerve growth factor pretreatment attenuates oxygen and glucose deprivation-induced c-Jun amino-terminal kinase 1 and stress-activated kinases p38alpha and p38beta activation and confers neuroprotection in the pheochromocytoma PC12 model. J. Mol. Neurosci. 22 (2004) 237-250
    • (2004) J. Mol. Neurosci. , vol.22 , pp. 237-250
    • Tabakman, R.1    Jiang, H.2    Schaefer, E.3    Levine, R.A.4    Lazarovici, P.5
  • 63
    • 0346219194 scopus 로고    scopus 로고
    • Interactions between the cells of the immune and nervous system: neurotrophins as neuroprotection mediators in CNS injury
    • Tabakman R., Lecht S., Sephanova S., Arien-Zakay H., and Lazarovici P. Interactions between the cells of the immune and nervous system: neurotrophins as neuroprotection mediators in CNS injury. Prog. Brain. Res. 146 (2004) 387-401
    • (2004) Prog. Brain. Res. , vol.146 , pp. 387-401
    • Tabakman, R.1    Lecht, S.2    Sephanova, S.3    Arien-Zakay, H.4    Lazarovici, P.5
  • 64
    • 29744447230 scopus 로고    scopus 로고
    • Neuroprotection by NGF in the PC12 in vitro OGD model: involvement of mitogen-activated protein kinases and gene expression
    • Tabakman R., Jiang H., Shahar I., Arien-Zakay H., Levine R.A., and Lazarovici P. Neuroprotection by NGF in the PC12 in vitro OGD model: involvement of mitogen-activated protein kinases and gene expression. Ann. N.Y. Acad. Sci. 1053 (2005) 84-96
    • (2005) Ann. N.Y. Acad. Sci. , vol.1053 , pp. 84-96
    • Tabakman, R.1    Jiang, H.2    Shahar, I.3    Arien-Zakay, H.4    Levine, R.A.5    Lazarovici, P.6
  • 65
    • 41149111290 scopus 로고    scopus 로고
    • In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain
    • Theus M.H., Wei L., Cui L., Francis K., Hu X., Keogh C., and Yu S.P. In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain. Exp. Neurol. 210 (2008) 656-670
    • (2008) Exp. Neurol. , vol.210 , pp. 656-670
    • Theus, M.H.1    Wei, L.2    Cui, L.3    Francis, K.4    Hu, X.5    Keogh, C.6    Yu, S.P.7
  • 66
    • 0037205044 scopus 로고    scopus 로고
    • Signaling pathways for PC12 cell differentiation: making the right connections
    • Vaudry D., Stork P.J., Lazarovici P., and Eiden L.E. Signaling pathways for PC12 cell differentiation: making the right connections. Science 296 (2002) 1648-1649
    • (2002) Science , vol.296 , pp. 1648-1649
    • Vaudry, D.1    Stork, P.J.2    Lazarovici, P.3    Eiden, L.E.4
  • 68
    • 0029619277 scopus 로고
    • Expression of mRNAs of multiple growth factors and receptors by neuronal cell lines: detection with RT-PCR
    • Zaheer A., Zhong W., and Lim R. Expression of mRNAs of multiple growth factors and receptors by neuronal cell lines: detection with RT-PCR. Neurochem. Res. 20 (1995) 1457-1463
    • (1995) Neurochem. Res. , vol.20 , pp. 1457-1463
    • Zaheer, A.1    Zhong, W.2    Lim, R.3


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