Regulation of neurotrophin-induced axonal responses via Rho GTPases

Journal of Comparative Neurology

Volumn 438, Issue 4, 2001, Pages 377-387

  Hande zdnler, P ^a   Erzurumlu, Reha S ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BDNF; NGF; NT 3; Rac; Rho; Trigeminal axon growth; Viral vectors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GUANOSINE TRIPHOSPHATASE; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; RAC PROTEIN; RHO FACTOR; TRACER; VIRUS VECTOR;

ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; NERVE CELL DIFFERENTIATION; NERVE FIBER; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE CELL; TRIGEMINUS GANGLION; VACCINIA VIRUS; VIRUS RECOMBINANT;

AFFERENT PATHWAYS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARBOCYANINES; CELL DIFFERENTIATION; CELL SIZE; FETUS; FLUORESCENT DYES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; GROWTH CONES; IMMUNOHISTOCHEMISTRY; LYSOPHOSPHOLIPIDS; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURONS, AFFERENT; NEUROTROPHIN 3; RAC GTP-BINDING PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RHO GTP-BINDING PROTEINS; TRANSFECTION; TRIGEMINAL GANGLION; TRIGEMINAL NUCLEI; VACCINIA VIRUS;

EID: 0035479438     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.1321     Document Type: Article

References (67)

1. Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth
2. Effectors for the Rho GT Pases
3. Drosphila trio plays an essential role in patterning of axons by regulating their directional extension
4. The quanine necleotide exchange factor trio mediates axonal development in the Drosophila embryo
5. Rho GT Pases and their effector proteins
6. Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons
7. Neurotrophin regulation of the developing nervous system: Analyses of knockout mice
8. Studies of neurotrophin biology in the developing trigeminal system
9. Developmental changes in the neurotrophin factor survival requirements of peripheral nervous system neurons
10. Overexpression of nerve growth factor in skin causes preferential increases among innervation to specific sensory targets
11. The multidomain protein trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
12. BAX is required for neuronal death after trophic factor deprivation and during development
13. Embryonic sensory development: Local expression of neurotrophin-3 and target expression of nerve growth factor
14. Developmental changes in the response of trigeminal neurons to neurotrophins: Influence of birthdate and the ganglion environment
15. Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development
16. Trigeminal ganglion cell processes are spatially ordered prior to the differentiation of the vibrissa pad
17. Chemotrophic effects of NGF, NT-3, and BDNF on embryonic central trigeminal tract axons
18. Neurotrophin signaling via Trks and p75
19. Neurotrophins and the dynamic regulation of the neuronal cytoskeleton
20. TrkA and TrkC co-expression in dissociated trigeminal ganglion cell cultures and axonal responses to NGF and NT-3
21. Rho GT Pases and the actin cytoskeleton
22. Signal transduction pathways regulated by the Rho family of small GT Pases
23. Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues
24. Expression of Trk receptors in the developing mouse trigeminal ganglion: In vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC
25. POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression
26. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
27. Rac1 mediates collapsin-1-induced growth cone collapse
28. Studying signal transduction in neuronal cells: The Trk/NGF system
29. Signal transduction by the neurotrophin receptors
30. Neurotrophin signal transduction in the nervous system
31. Signaling to Rho GT Pases
32. Trks: Signal transduction and intracellular pathways
33. Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells
34. Rho family GT Pases and neuronal growth cone remodeling: Relationship between increased complexity induced by Cdc42Hs, Rac 1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
35. Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPases
36. Inactivation of Rho signaling pathway promotes CNS axon regeneration
37. Neurotrophins support the development of diverse sensory axon morphologies
38. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo
39. Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding
40. Cytoskeletal reorganization underlying growth cone motility
41. Orchestral maneuvers in the axon: Trio and the control of axon guidance
42. Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck
43. Differential effects of the Rac GTPase on Purkinie cell axons and dendritic trunks and spines
44. Rho family GTP-binding proteins in growth cone signalling
45. Rho GT Pases
46. NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression
47. Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
48. Growth cone guidance: First steps toward a deeper understanding
49. Small GTPases rac and rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons
50. Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila
51. Development of sensory neurons in the absence of NGF/TrkA signaling in vivo
52. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
53. The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPaes in vivo
54. Photoconversion of some fluorescent markers to a diaminobenzidine product
55. Signal transduction underlying growth cone guidance by diffusible factors
56. Rho, Rac and Cdc42 GT Pases regulate the organization of the actin cytoskeleton
57. Regulation of dendritic spine morphology by the rho family of small GTPases: Antagonistic roles of rac and Rho
58. Regulation of dendritic growth and remodeling by Rho, Rac and Cdc42
59. Neurotrophins are required for nerve growth during development
60. Differential effects of NGF and NT-3 on embryonic trigeminal axon growth parameters
61. Rho GTPases and signaling networks
62. Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase
63. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia
64. Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
65. Role of a new Rho family member in cell migration and axon guidance in C. elegans