Regulation of pituitary adenylate cyclase activating polypeptide and its receptor type 1 after traumatic brain injury: Comparison with brain-derived neurotrophic factor and the induction of neuronal cell death

Neuroscience

Volumn 90, Issue 1, 1999, Pages 235-247

  Skoglosa Y ^a   Lewen A ^b   Takei, N ^a   Hillered, L ^b   Lindholm, D ^a  

^a Devmtl Neurbio Box 587 B ^*  (Sweden)

^b Department of Neuroscience   (Sweden)

Author keywords

BDNF; Brain trauma; Cell death; Gene regulation; In situ hybridization; PACAP

Indexed keywords

ADENYLATE CYCLASE; BRAIN DERIVED NEUROTROPHIC FACTOR;

ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL DEATH; CELL SURVIVAL; ENZYME LOCALIZATION; GENE CONTROL; HYPOPHYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; DISEASE MODELS, ANIMAL; IN SITU HYBRIDIZATION; MALE; NEURONS; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RECEPTORS, PITUITARY HORMONE; RNA, MESSENGER;

EID: 0345320465     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00414-X     Document Type: Article

References (72)

1. Arimura A. Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research. Regul. Pept. 37:1992;287-303.
2. Arimura A., Shioda S. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction. Front. Neuroendocr. 16:1995;53-88.
3. Arimura A., Somogyvari-Vigh A., Weill C., Fiore R.C., Tatsuno I., Bay V., Brenneman D.E. PACAP functions as a neurotrophic factor. Ann. N. Y. Acad. Sci. 739:1994;228-243.
4. Banks W.A., Uchida D., Arimura A., Somogyvari-Vigh A., Shioda S. Transport of pituitary adenylate cyclase-activating polypeptide across the blood-brain barrier and the prevention of ischemia-induced death of hippocampal neurons. Ann. N. Y. Acad. Sci. 805:1996;270-277.
5. Barbacid M. The Trk family of neurotrophin receptors. J. Neurobiol. 25:1994;1386-1403.
6. Barde Y.-A. Trophic factors and neuronal survival. Neuron. 2:1989;1525-1534.
7. Basille M., Gonzalez B.J., Leroux P., Jeandel L., Fournier A., Vaudry H. Localization and characterization of PACAP receptors in the rat cerebellum during development: evidence for a stimulatory effect of PACAP on immature cerebellar granule cells. Neuroscience. 57:1993;329-338.
8. Beck T., Lindholm D., Castren E., Wree A. Brain derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. J. cerebr. Blood Flow Metab. 14:1994;689-692.
9. Castrén E., Thoenen H., Lindholm D. Brain-derived neurotrophic factor messenger RNA is expressed in the septum, hypothalamus and in adrenergic brain stem nuclei of adult rat brain and is increased by osmotic stimulation in the paraventricular nucleus. Neuroscience. 64:1995;71-80.
10. Cavallaro S., Copani A., D'Agata V., Musco S., Petralia S., Ventra C., Stivala F., Travali S., Canonico P.L. Pituitary adenylate cyclase activating polypeptide prevents apoptosis in cultured cerebellar granule neurons. Molec. Pharmac. 50:1996;60-66.
11. Cheng B., Goodman Y., Begley J.G., Mattson M.P. Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury. Brain Res. 650:1994;331-335.
12. Cheng B., Mattson M. NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis. Neuron. 7:1991;1031-1041.
13. Cheng B., Mattson M. NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain Res. 640:1994;56-67.
14. Clark R.S., Chen J., Watkins S.C., Kochanek P.M., Chen M., Stetler R.A., Loeffert J.E., Graham S.H. Apoptosis suppressor gene bcl-2 expression after traumatic brain injury in rats. J. Neurosci. 17:1997;9172-9182.
15. D'Agata V., Cavallaro S., Stivala F., Canonico P.L. Tissue-specific and developmental expression of pituitary adenylate cyclase-activating polypeptide (PACAP) receptors in rat brain. Eur. J. Neurosci. 8:1996;310-318.
16. Davies A.M. The role of neurotrophins in the developing nervous system. J. Neurobiol. 25:1994;1334-1348.
17. DeKosky S.T., Goss J.R., Miller P.D., Styren S.D., Kochanek P.M., Marion D. Upregulation of nerve growth factor following cortical trauma. Expl Neurol. 130:1994;173-177.
18. Desphande J., Bergstedt K., Linden T., Kalimo H., Wieloch T. Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death. Expl Brain Res. 88:1992;91-105.
19. Deutsch P.J., Sun Y. The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signalling cascades in PC12 cells and promotes neurite outgrowth. J. biol. Chem. 267:1992;5108-5113.
20. DiCicco-Bloom E., Deutsch P.J. Pituitary adenylate cyclase activating polypeptide (PACAP) potently stimulates mitosis, neuritogenesis and survival in cultured rat sympathetic neuroblasts. Regul. Pept. 37:1992;319.
21. Dixon C.E., Flinn P., Bao J., Venya R., Hayes R.L. Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats. Expl Neurol. 146:1997;479-490.
22. Ernfors P., Wetmore C., Olson L., Persson H. Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron. 5:1990;511-526.
23. Faden A., Demediuk P., Panter S.S., Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science. 244:1989;798-800.
24. Gall C.M., Isackson P.J. Limbic seizures increase neuronal production of messenger RNA for nerve growth factor. Science. 244:1989;758-761.
25. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
26. Hashimoto H., Nogi H., Mori K., Ohishi H., Shigemoto R., Yamamoto K., Matsuda T., Mizuno N., Nagata S., Baba A. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. J. comp. Neurol. 371:1996;567-577.
27. Hayes R.L., Yang K., Whitson J.S., Xue J.J., Kampfl A., Mu X.S., Zhao X., Faustinella F., Clifton G.L. Rescue of injury induced neurofilament loss by BDNF gene transfection in primary septohippocampal cell cultures. Neurosci. Lett. 191:1995;121-125.
28. Hernandez A., Kimball B., Romanchuk G., Mulholland M.W. Pituitary adenylate cyclase-activating peptide stimulates neurite growth in PC12 cells. Peptides. 16:1995;927-932.
29. Hicks R.R., Numan S., Dhillon H.S., Prasad M.R., Seroogy K.B. Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma. Molec. Brain Res. 48:1997;401-406.
30. Isackson P.J., Huntsman M.M., Murray K.D., Gall C.M. BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron. 6:1991;937-948.
31. Kaiser P.K., Lipton S.A. VIP-mediated increase in cAMP prevents tetrodotoxin-induced retinal ganglion cell death in vitro. Neuron. 5:1990;373-381.
32. Kivipelto L., Absood A., Arimura A., Sundler F., Hakanson R., Panula P. The distribution of pituitary adenylate cyclase-activating polypeptide-like immunoreactivity is distinct from helodermin- and helospectin-like immunoreactivities in the rat brain. J. chem. Neuroanat. 5:1992;85-94.
33. Kokaia Z., Nawa H., Uchino H., Elmer E., Kokaia M., Carnahan J., Smith M.L., Siesjo B.K., Lindvall O. Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat. Molec. Brain Res. 38:1996;139-144.
34. Larsen J.O., Hannibal J., Knudsen S.M., Fahrenkrug J. Expression of pituitary adenylate cyclase-activating polypeptide (PACAP) in the mesencephalic trigeminal nucleus of the rat after transection of the masseteric nerve. Molec. Brain Res. 46:1997;109-117.
35. Lewen A., Li G.L., Olsson Y., Hillered L. Changes in microtubule-associated protein 2 and amyloid percursor protein immunoreactivity following traumatic brain injury in rat: influence of MK-801 treatment. Brain Res. 719:1996;161-171.
36. Lewén A., Soderstrom S., Hillered L., Ebendal T. Expression of serine/treonine kinase receptors in traumatic brain injury. NeuroReport. 8:1997;475-479.
37. Lewin G., Barde Y.-A. Physiology of the neurotrophins. A. Rev. Neurosci. 19:1996;289-317.
38. Lindholm D., Carroll P., Tzimagiorgis G., Thoenen H. Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4. Eur. J. Neurosci. 8:1996;1452-1460.
39. Lindholm D., Castrén E., Berzaghi M., Blochl A., Thoenen H. Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain - implications for neuronal plasticity. J. Neurobiol. 25:1994;1362-1372.
40. Lindholm D., Castren E., Kiefer R., Zafra F., Thoenen H. Transforming growth factor-b1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J. Cell Biol. 117:1992;395-400.
41. Lindholm D., Dechant G., Heisenberg C.P., Thoenen H. Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur. J. Neurosci. 5:1993;1455-1464.
42. Lindsay R.M. Neurotrophic growth factors and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neurotrophic factor. Neurobiol. Aging. 15:1994;249-251.
43. Lindsay R.M., Wiegand S.J., Altar C.A., DiStefano P.S. Neurotrophic factors: from molecule to man. Trends Neurosci. 19:1994;182-190.
44. Lindvall O., Ernfors P., Bengzon J., Kokaia Z., Smith M.L., Siesjo B.K., Persson H. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc. natn. Acad. Sci. U.S.A. 89:1992;648-652.
45. Lindvall O., Kokaia Z., Bengzon J., Elmer E., Kokaia M. Neurotrophins and brain insults. Trends Neurosci. 17:1994;490-496.
46. Lioudyno M., Skoglösa Y., Takei N., Lindholm D. Pituitary adenylate cyclase-activating polypeptide (PACAP) protects dorsal root ganglion neurons from death and induces calcitonin gene-related peptide (CGRP) immunoreactivity in vitro. J. Neurosci. Res. 51:1998;243-256.
47. Longo F. M. (1993) Neurotransmitters as neurotrophic factors. In Neurotrophic Factors (eds Loughlin S. E. and Fallon J. H.), pp. 565-598. Academic, London.
48. Lu N., DiCicco-Bloom E. Pituitary adenylate cyclase activating polypeptide is an autocrine inhibitor of mitosis in cultured cortical precursor cells. Proc. natn. Acad. Sci. U.S.A. 94:1997;3357-3362.
49. Marty S., Berninger B., Carroll P., Thoenen H. GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron. 16:1996;565-570.
50. Miyata A., Arimura A., Dahl R.R., Minamiro N., Uehara A., Jiang L., Culler M.D., Coy D.H. Isolation of a novel 38-residue hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem. biophys. Res. Commun. 164:1989;567-574.
51. Miyata A., Jiang L., Dahl R.D., Kitada C., Kubo K., Fujino M., Minamino N., Arimura A. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem. biophys. Res. Commun. 170:1990;643-648.
52. Morio H., Tatsuno I., Hirai A., Tamura Y., Saito Y. Pituitary adenylate cyclase-activating polypeptide protects rat-cultured cortical neurons from glutamate-induced cytotoxicity. Brain Res. 741:1996;82-88.
53. 2+ levels following cortical compression contusion trauma in rats. J. cerebr. Blood Flow Metab. 13:1993;183-192.
54. Nilsson P., Laursen H., Hillered L., Hansen A.J. Calcium movements in traumatic brain injury: the role of glutamate receptor-operated ion channels. J. cerebr. Blood Flow Metab. 16:1996;262-270.
55. Nitatori T., Sato N., Waguri S., Karasawa Y., Araki H., Shibanai K., Kominami E., Uchiyama Y. Delayed neuronal death in the CAl pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. 15:1995;1001-1011.
56. Ogi K., Kimura C., Onda H., Arimura A., Fujino M. Molecular cloning and characterization of cDNA for the precursor of rat pituitary adenylate cyclase activating polypeptide (PACAP). Biochem. biophys. Res. Commun. 173:1990;1271-1279.
57. Pincus D.W., DiCicco-Bloom E., Black I.B. Vasoactive intestinal peptide regulation of neuroblast mitosis and survival: role of cAMP. Brain Res. 514:1990;355-357.
58. Portera-Cailliau C., Price D.L., Martin L.J. Non-NMDA and NMDA receptor-mediated excitotoxic neuronal death in adult brain are morphological distinct: further evidence for an apoptosis-necrosis continuum. J. comp. Neurol. 378:1997;88-104.
59. Rawlings S.R., Hezareh M. Pituitary adenylate cyclase activating polypeptide (PACAP) and PACAP/vasoactive intestinal polypeptide receptors: actions on the anterior pituitary gland. Endocr. Rev. 17:1996;4-29.
60. Rink A., Fung K.-M., Trojanowski L., Lee V.M.Y., Neugebauer E., McIntosh T.K. Evidence of apoptotic cell death after experimental brain injury in the rat. Am. J. Path. 147:1995;1575-1583.
61. Schwartz J.P. Neurotransmitters as neurotrophic factors - a new set of functions. Int. Rev. Neurobiol. 34:1992;1-23.
62. Shuto Y., Uchida D., Onda H., Arimura A. Ontogeny of pituitary adenylate cyclase activating polypeptide and its receptor mRNA in the mouse brain. Regul. Pept. 67:1996;79-83.
63. Skoglösa Y., Takei N. and Lindholm D. (1997) Distribution of pituitary cyclase activating polypeptide mRNA in the developing rat brain and the effect of PACAP on survival of hippocampal neurons in culture. In Society for Neuroscience, 27th Annual Meeting. New Orleans, LA.
64. Spengler D., Waeber C., Pantaloni C., Holsboer F., Bockaert J., Seeburg P.H., Journot L. Differential signal transduction by five splice variants of the PACAP receptor. Nature. 365:1993;170-175.
65. 2+ ionophore-induced apoptosis of cultured embryonic rat cortical neurons. Brain Res. 652:1994;65-70.
66. Tatsuno I., Somogyvari-Vigh A., Arimura A. Developmental changes of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor in the rat brain. Peptides. 15:1994;55-60.
67. Tatsuno I., Yada T., Vigh S., Hidaka H., Arimura A. Pituitary adenylate cyclase activating polypeptide and vasoactive intestinal peptide increase cytosolic free calcium concentration in cultured rat hippocampal neurons. Endocrinology. 131:1992;73-81.
68. Tsukahara T., Yonekawa Y., Tanaka K., Ohara O., Wantanabe S., Kimura T., Nishijima T., Taniguchi T. The role of brain-derived neurotrophic factor in transient forebrain ischemia in the rat brain. Neurosurgery. 34:1994;323-331.
69. Villalba M., Bockaert J., Journot L. Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway. J. Neurosci. 17:1997;83-90.
70. Zafra F., Hengerer B., Leibrock J., Thoenen H., Lindholm D. Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. Eur. molec. Biol. Org. J. 9:1990;3545-3550.
71. Zhang Q., Shi T.J., Ji R.R., Zhang Y., Sundler F., Hannibal J., Fahrenkrug J., Hokfelt T. Expression of pituitary adenylate cyclase-activating polypeptide in dorsal root ganglia following axotomy: time course and coexistence. Brain Res. 705:1995;149-158.
72. Zirrgiebel U., Ohga Y., Carter B., Berninger B., Inagaki N., Thoenen H., Lindholm D. Characterization of TrkB receptor mediated signalling pathways in rat cerebellar granule neurons: involvement of protein kinase C in neuronal survival. J. Neurochem. 65:1995;2241-2250.