메뉴 건너뛰기




Volumn , Issue , 2012, Pages 621-642

Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke Injury

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84868149276     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374947-5.00035-3     Document Type: Chapter
Times cited : (4)

References (98)
  • 1
    • 0037174635 scopus 로고    scopus 로고
    • Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions
    • Aarts M., Liu Y., Liu L., et al. Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science 2002, 298:846-850.
    • (2002) Science , vol.298 , pp. 846-850
    • Aarts, M.1    Liu, Y.2    Liu, L.3
  • 2
    • 0036661083 scopus 로고    scopus 로고
    • Aquaporin water channels-from atomic structure to clinical medicine
    • Agre P., King L.S., Yasui M., et al. Aquaporin water channels-from atomic structure to clinical medicine. Journal of Physiology 2002, 542:3-16.
    • (2002) Journal of Physiology , vol.542 , pp. 3-16
    • Agre, P.1    King, L.S.2    Yasui, M.3
  • 3
    • 24744471893 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury, reactive oxygen metabolites, and the surgeon
    • Aktan A.O., Yalcin A.S. Ischemia-reperfusion injury, reactive oxygen metabolites, and the surgeon. Turkish Journal of Medical Sciences 1998, 28:1-5.
    • (1998) Turkish Journal of Medical Sciences , vol.28 , pp. 1-5
    • Aktan, A.O.1    Yalcin, A.S.2
  • 4
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • Allen C.L., Bayraktutan U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. International Journal of Stroke 2009, 4:461-470.
    • (2009) International Journal of Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 6
    • 17444412714 scopus 로고    scopus 로고
    • Neuroprotectin D1 (NPD1): A DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress
    • Bazan N.G. Neuroprotectin D1 (NPD1): A DHA-derived mediator that protects brain and retina against cell injury-induced oxidative stress. Brain Pathology 2005, 15:159-166.
    • (2005) Brain Pathology , vol.15 , pp. 159-166
    • Bazan, N.G.1
  • 7
    • 66349115906 scopus 로고    scopus 로고
    • Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease
    • Bazan N.G. Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease. Journal of Lipid Research 2009, 50:S400-S405.
    • (2009) Journal of Lipid Research , vol.50
    • Bazan, N.G.1
  • 8
    • 0030580410 scopus 로고    scopus 로고
    • Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats
    • Belayev L., Busto R., Zhao W., et al. Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Research 1996, 739:88-96.
    • (1996) Brain Research , vol.739 , pp. 88-96
    • Belayev, L.1    Busto, R.2    Zhao, W.3
  • 9
    • 70349256214 scopus 로고    scopus 로고
    • Robust docosahexaenoic acid-mediated neuroprotection in a rat model of transient, focal cerebral ischemia
    • Belayev L., Khoutorova L., Atkins K.D., et al. Robust docosahexaenoic acid-mediated neuroprotection in a rat model of transient, focal cerebral ischemia. Stroke 2009, 40:3121-3126.
    • (2009) Stroke , vol.40 , pp. 3121-3126
    • Belayev, L.1    Khoutorova, L.2    Atkins, K.D.3
  • 10
  • 11
    • 0035133027 scopus 로고    scopus 로고
    • Human albumin therapy of acute ischemic stroke: Marked neuroprotective efficacy at moderate doses and with a broad therapeutic window
    • Belayev L., Liu Y., Zhao W., et al. Human albumin therapy of acute ischemic stroke: Marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke 2001, 32:553-560.
    • (2001) Stroke , vol.32 , pp. 553-560
    • Belayev, L.1    Liu, Y.2    Zhao, W.3
  • 12
    • 11144224909 scopus 로고    scopus 로고
    • Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection
    • Belayev L., Marcheselli V.L., Khoutorova L., et al. Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection. Stroke 2005, 36:118-123.
    • (2005) Stroke , vol.36 , pp. 118-123
    • Belayev, L.1    Marcheselli, V.L.2    Khoutorova, L.3
  • 13
    • 0036217242 scopus 로고    scopus 로고
    • Albumin therapy of transient focal cerebral ischemia: In vivo analysis of dynamic microvascular responses
    • Belayev L., Pinard E., Nallet H., et al. Albumin therapy of transient focal cerebral ischemia: In vivo analysis of dynamic microvascular responses. Stroke 2002, 33:1077-1084.
    • (2002) Stroke , vol.33 , pp. 1077-1084
    • Belayev, L.1    Pinard, E.2    Nallet, H.3
  • 14
    • 0032879535 scopus 로고    scopus 로고
    • Neuroprotective effect of high-dose albumin therapy against global ischemic brain injury in rats
    • Belayev L., Saul I., Huh P.W., et al. Neuroprotective effect of high-dose albumin therapy against global ischemic brain injury in rats. Brain Research 1999, 845:107-111.
    • (1999) Brain Research , vol.845 , pp. 107-111
    • Belayev, L.1    Saul, I.2    Huh, P.W.3
  • 15
    • 0141724805 scopus 로고    scopus 로고
    • A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
    • Borsello T., Clarke P.G., Hirt L., et al. A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nature Medicine 2003, 9:1180-1186.
    • (2003) Nature Medicine , vol.9 , pp. 1180-1186
    • Borsello, T.1    Clarke, P.G.2    Hirt, L.3
  • 16
    • 67649579964 scopus 로고    scopus 로고
    • Efficacy of citicoline as an acute stroke treatment
    • Clark W.M. Efficacy of citicoline as an acute stroke treatment. Expert Opinion on Pharmacotherapy 2009, 10:839-846.
    • (2009) Expert Opinion on Pharmacotherapy , vol.10 , pp. 839-846
    • Clark, W.M.1
  • 17
    • 13344283416 scopus 로고    scopus 로고
    • Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke
    • Connolly E.S., Winfree C.J., Springer T.A., et al. Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke. Journal of Clinical Investigation 1996, 97:209-216.
    • (1996) Journal of Clinical Investigation , vol.97 , pp. 209-216
    • Connolly, E.S.1    Winfree, C.J.2    Springer, T.A.3
  • 18
    • 84882531604 scopus 로고    scopus 로고
    • Dynamic perfusion-CT assessment of early changes in blood-brain barrier permeability of acute ischaemic stroke patients
    • Dankbaar J.W., Hom J., Schneider T., et al. Dynamic perfusion-CT assessment of early changes in blood-brain barrier permeability of acute ischaemic stroke patients. Journal of Neuroradiology 2010.
    • (2010) Journal of Neuroradiology
    • Dankbaar, J.W.1    Hom, J.2    Schneider, T.3
  • 19
    • 33847728252 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury: Processes in pathogenetic networks: A review
    • de Groot H., Rauen U. Ischemia-reperfusion injury: Processes in pathogenetic networks: A review. Transplantation Proceedings 2007, 39:481-484.
    • (2007) Transplantation Proceedings , vol.39 , pp. 481-484
    • de Groot, H.1    Rauen, U.2
  • 21
    • 0025947863 scopus 로고
    • Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons
    • del Zoppo G.J., Schmid-Schönbein G.W., Mori E., et al. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 1991, 22:1276-1283.
    • (1991) Stroke , vol.22 , pp. 1276-1283
    • del Zoppo, G.J.1    Schmid-Schönbein, G.W.2    Mori, E.3
  • 22
    • 0024555775 scopus 로고
    • Transient blood-brain barrier permeability following profound temporary global ischaemia: An experimental study using 14C-AIB
    • Dobbin J., Crockard H.A., Ross-Russell R. Transient blood-brain barrier permeability following profound temporary global ischaemia: An experimental study using 14C-AIB. Journal of Cerebral Blood Flow and Metabolism 1989, 9:71-78.
    • (1989) Journal of Cerebral Blood Flow and Metabolism , vol.9 , pp. 71-78
    • Dobbin, J.1    Crockard, H.A.2    Ross-Russell, R.3
  • 23
    • 58149194564 scopus 로고    scopus 로고
    • Ebinger M., De Silva D.A., Christensen S., et al. Imaging the penumbra-strategies to detect tissue at risk after ischemic stroke. Journal of Clinical Neuroscience 2009, 16:178-187.
    • (2006) , vol.355 , pp. 730-732
    • Ebinger, M.1    De Silva, D.A.2    Christensen, S.3
  • 24
    • 58149194564 scopus 로고    scopus 로고
    • Imaging the penumbra-strategies to detect tissue at risk after ischemic stroke
    • Imaging the penumbra-strategies to detect tissue at risk after ischemic stroke. Journal of Clinical Neuroscience 2009, 16: 178-187.
    • (2009) Journal of Clinical Neuroscience , vol.16 , pp. 178-187
  • 25
    • 1542317072 scopus 로고    scopus 로고
    • Reactive astrocytes protect tissue and preserve function after spinal cord injury
    • Faulkner J.R., Herrmann J.E., Woo M.J., et al. Reactive astrocytes protect tissue and preserve function after spinal cord injury. The Journal of Neuroscience 2004, 24:2143-2155.
    • (2004) The Journal of Neuroscience , vol.24 , pp. 2143-2155
    • Faulkner, J.R.1    Herrmann, J.E.2    Woo, M.J.3
  • 26
    • 33646480216 scopus 로고    scopus 로고
    • The ischemic penumbra: A new opportunity for neuroprotection
    • Fisher M. The ischemic penumbra: A new opportunity for neuroprotection. Cerebrovascular Diseases 2006, 2:64-70.
    • (2006) Cerebrovascular Diseases , vol.2 , pp. 64-70
    • Fisher, M.1
  • 27
    • 79952117976 scopus 로고    scopus 로고
    • New approaches to neuroprotective drug development
    • Fisher M. New approaches to neuroprotective drug development. Stroke 2011, 42:S24-S27.
    • (2011) Stroke , vol.42
    • Fisher, M.1
  • 28
    • 0033510014 scopus 로고    scopus 로고
    • Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases
    • Fiskum G., Murphy A.N., Beal M.F. Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases. Journal of Cerebral Blood Flow and Metabolism 1999, 19:351-369.
    • (1999) Journal of Cerebral Blood Flow and Metabolism , vol.19 , pp. 351-369
    • Fiskum, G.1    Murphy, A.N.2    Beal, M.F.3
  • 29
    • 79451470799 scopus 로고    scopus 로고
    • The albumin in acute stroke (ALIAS) multicenter clinical trial: Safety analysis of part 1 and rationale and design of part 2
    • Ginsberg M.D., Palesch Y.Y., Martin R.H., et al. The albumin in acute stroke (ALIAS) multicenter clinical trial: Safety analysis of part 1 and rationale and design of part 2. Stroke 2011, 42:119-127.
    • (2011) Stroke , vol.42 , pp. 119-127
    • Ginsberg, M.D.1    Palesch, Y.Y.2    Martin, R.H.3
  • 30
    • 0034780566 scopus 로고    scopus 로고
    • And combination therapy stroke trial investigators. combination therapy stroke trial: Recombinant tissue-type plasminogen activator with/without lubeluzole
    • Grotta J. and combination therapy stroke trial investigators. combination therapy stroke trial: Recombinant tissue-type plasminogen activator with/without lubeluzole. Cerebrovascular Diseases 2001, 12:258-263.
    • (2001) Cerebrovascular Diseases , vol.12 , pp. 258-263
    • Grotta, J.1
  • 32
    • 77955853154 scopus 로고    scopus 로고
    • Implications of immune system in stroke for novel therapeutic approaches
    • Hall A.A., Pennypacker K.R. Implications of immune system in stroke for novel therapeutic approaches. Translational Stroke Research 2010, 1:85-95.
    • (2010) Translational Stroke Research , vol.1 , pp. 85-95
    • Hall, A.A.1    Pennypacker, K.R.2
  • 33
    • 0029688435 scopus 로고    scopus 로고
    • Neuroprotective efficacy of microvascularly localized versus brain-penetrating antioxidants
    • Hall E.D., Andrus P.K., Smith S.L., et al. Neuroprotective efficacy of microvascularly localized versus brain-penetrating antioxidants. Acta Neurologica Supplementum 1996, 66:107-113.
    • (1996) Acta Neurologica Supplementum , vol.66 , pp. 107-113
    • Hall, E.D.1    Andrus, P.K.2    Smith, S.L.3
  • 34
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. Reactive oxygen species and the central nervous system. Journal of Neurochemistry 1992, 59:1609-1623.
    • (1992) Journal of Neurochemistry , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 35
    • 77956917231 scopus 로고    scopus 로고
    • Synaptic versus extra-synaptic NMDA receptor signaling: Implications for neurodegenerative disorders
    • Hardingham G.E., Bading H. Synaptic versus extra-synaptic NMDA receptor signaling: Implications for neurodegenerative disorders. Nature Reviews Neuroscience 2010, 11:682-696.
    • (2010) Nature Reviews Neuroscience , vol.11 , pp. 682-696
    • Hardingham, G.E.1    Bading, H.2
  • 36
    • 77955163006 scopus 로고    scopus 로고
    • The concept of the penumbra: Can it be translated to stroke management?
    • Heiss W.D. The concept of the penumbra: Can it be translated to stroke management?. International Journal of Stroke 2010, 5:290-295.
    • (2010) International Journal of Stroke , vol.5 , pp. 290-295
    • Heiss, W.D.1
  • 37
    • 70350349527 scopus 로고    scopus 로고
    • Pathophysiological basis of translational stroke research
    • Hossmann K.M.A. Pathophysiological basis of translational stroke research. Folia Neuropathologica 2009, 47:213-227.
    • (2009) Folia Neuropathologica , vol.47 , pp. 213-227
    • Hossmann, K.M.A.1
  • 38
    • 77952547253 scopus 로고    scopus 로고
    • Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator
    • Jin R., Yang G., Li G. Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator. Neurobiology of Disease 2010, 38:376-385.
    • (2010) Neurobiology of Disease , vol.38 , pp. 376-385
    • Jin, R.1    Yang, G.2    Li, G.3
  • 39
    • 1642602666 scopus 로고    scopus 로고
    • Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: A population-based study
    • Kleindorfer D., Kissela B., Schneider A., et al. Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: A population-based study. Stroke 2004, 35:27-29.
    • (2004) Stroke , vol.35 , pp. 27-29
    • Kleindorfer, D.1    Kissela, B.2    Schneider, A.3
  • 40
    • 77949263575 scopus 로고    scopus 로고
    • Acute stroke magnetic resonance imaging: Current status and future perspective
    • Kloska S.P., Wintermark M., Engelhorn T., et al. Acute stroke magnetic resonance imaging: Current status and future perspective. Neuroradiology 2010, 52:189-201.
    • (2010) Neuroradiology , vol.52 , pp. 189-201
    • Kloska, S.P.1    Wintermark, M.2    Engelhorn, T.3
  • 43
    • 84879354266 scopus 로고    scopus 로고
    • Quercetin reduces the elevated matrix metalloproteinases-9 level and improves functional outcome after cerebral focal ischemia in rats
    • Lee J.K., Kwak H.J., Piao M.S., et al. Quercetin reduces the elevated matrix metalloproteinases-9 level and improves functional outcome after cerebral focal ischemia in rats. Acta Neurologica 2010.
    • (2010) Acta Neurologica
    • Lee, J.K.1    Kwak, H.J.2    Piao, M.S.3
  • 44
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
    • Lipton S.A. Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond. Nature Reviews Discovery 2006, 5:160-170.
    • (2006) Nature Reviews Discovery , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 45
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D., Adams R., Carnethon M., et al. Heart disease and stroke statistics-2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009, 119:e21-e181.
    • (2009) Circulation , vol.119
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3
  • 46
    • 0842289222 scopus 로고    scopus 로고
    • TPA and proteolysis in the neurovascular unit
    • Lo E.H., Broderick J.P., Moskowitz M.A. tPA and proteolysis in the neurovascular unit. Stroke 2004, 35:354-356.
    • (2004) Stroke , vol.35 , pp. 354-356
    • Lo, E.H.1    Broderick, J.P.2    Moskowitz, M.A.3
  • 49
    • 26444598506 scopus 로고    scopus 로고
    • A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease
    • Lukiw W.J., Cui J.G., Marcheselli V.L., et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. Journal of Clinical Investigation 2005, 115:2774-2783.
    • (2005) Journal of Clinical Investigation , vol.115 , pp. 2774-2783
    • Lukiw, W.J.1    Cui, J.G.2    Marcheselli, V.L.3
  • 50
    • 0035833953 scopus 로고    scopus 로고
    • The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): Final results
    • Lyden P., Jacoby M., Schim J., et al. The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): Final results. Neurology 2001, 57:1199-1205.
    • (2001) Neurology , vol.57 , pp. 1199-1205
    • Lyden, P.1    Jacoby, M.2    Schim, J.3
  • 51
    • 0034753649 scopus 로고    scopus 로고
    • Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia
    • Ma J., Qiu J., Hirt L., et al. Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia. British Journal of Pharmacology 2001, 133:345-350.
    • (2001) British Journal of Pharmacology , vol.133 , pp. 345-350
    • Ma, J.1    Qiu, J.2    Hirt, L.3
  • 52
    • 0242290167 scopus 로고    scopus 로고
    • Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
    • Marcheselli V.L., Hong S., Lukiw W.J., et al. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. The Journal of Biological Chemistry 2003, 278:43807-43817.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 43807-43817
    • Marcheselli, V.L.1    Hong, S.2    Lukiw, W.J.3
  • 53
    • 2942538277 scopus 로고    scopus 로고
    • Hypoxic tissue in ischaemic stroke: Persistence and clinical consequences of spontaneous survival
    • Markus R., Reutens D.C., Kazui S., et al. Hypoxic tissue in ischaemic stroke: Persistence and clinical consequences of spontaneous survival. Brain 2004, 127:1427-1436.
    • (2004) Brain , vol.127 , pp. 1427-1436
    • Markus, R.1    Reutens, D.C.2    Kazui, S.3
  • 54
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • Mehta S.L., Manhas N., Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Research Reviews 2007, 54:34-66.
    • (2007) Brain Research Reviews , vol.54 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 55
    • 46249090912 scopus 로고    scopus 로고
    • Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia
    • Minnerup J., Heidrich J., Wellmann J., et al. Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia. Stroke 2008, 39:1855-1861.
    • (2008) Stroke , vol.39 , pp. 1855-1861
    • Minnerup, J.1    Heidrich, J.2    Wellmann, J.3
  • 56
    • 79952116549 scopus 로고    scopus 로고
    • Reperfusion therapies for acute ischemic stroke: Current pharmacological and mechanical approaches
    • Molina C.A. Reperfusion therapies for acute ischemic stroke: Current pharmacological and mechanical approaches. Stroke 2011, 42:S16-S19.
    • (2011) Stroke , vol.42
    • Molina, C.A.1
  • 57
    • 77955487488 scopus 로고    scopus 로고
    • The science of stroke: Mechanisms in search of treatments
    • Moskowitz M.A., Lo E.H., Iadecola C. The science of stroke: Mechanisms in search of treatments. Neuron 2010, 67:181-198.
    • (2010) Neuron , vol.67 , pp. 181-198
    • Moskowitz, M.A.1    Lo, E.H.2    Iadecola, C.3
  • 58
    • 49449106453 scopus 로고    scopus 로고
    • Molecular mechanisms of apoptosis in cerebral ischemia: Multiple neuroprotective opportunities
    • Nakka V.P., Gusain A., Mehta S.L., et al. Molecular mechanisms of apoptosis in cerebral ischemia: Multiple neuroprotective opportunities. Molecular Neurobiology 2008, 37:7-38.
    • (2008) Molecular Neurobiology , vol.37 , pp. 7-38
    • Nakka, V.P.1    Gusain, A.2    Mehta, S.L.3
  • 60
    • 79953236036 scopus 로고    scopus 로고
    • Nuclear neuroimaging in acute and subacute ischemic stroke
    • Oku N., Kashiwagi T., Hatazawa J., et al. Nuclear neuroimaging in acute and subacute ischemic stroke. Annals of Nuclear Medicine 2010, 24:629-638.
    • (2010) Annals of Nuclear Medicine , vol.24 , pp. 629-638
    • Oku, N.1    Kashiwagi, T.2    Hatazawa, J.3
  • 61
    • 33747155340 scopus 로고    scopus 로고
    • The ALIAS Pilot Trial: A dose-escalation and safety study of albumin therapy for acute ischemic stroke-II: Neurologic outcome and efficacy analysis
    • Palesch Y.Y., Hill M.D., Ryckborst K.J., et al. The ALIAS Pilot Trial: A dose-escalation and safety study of albumin therapy for acute ischemic stroke-II: Neurologic outcome and efficacy analysis. Stroke 2006, 37.
    • (2006) Stroke , vol.37
    • Palesch, Y.Y.1    Hill, M.D.2    Ryckborst, K.J.3
  • 62
    • 33846866507 scopus 로고    scopus 로고
    • Reperfusion injury following cerebral ischemia: Pathophysiology, MR imaging, and potential therapies
    • Pan J., Konstas A.A., Bateman B., et al. Reperfusion injury following cerebral ischemia: Pathophysiology, MR imaging, and potential therapies. Neuroradiology 2007, 49:93-102.
    • (2007) Neuroradiology , vol.49 , pp. 93-102
    • Pan, J.1    Konstas, A.A.2    Bateman, B.3
  • 63
    • 0026501717 scopus 로고
    • Pathophysiology of acute ischaemic stroke
    • Pulsinelli W. Pathophysiology of acute ischaemic stroke. Lancet 1992, 339:533-536.
    • (1992) Lancet , vol.339 , pp. 533-536
    • Pulsinelli, W.1
  • 64
    • 79952117075 scopus 로고    scopus 로고
    • Targeting the Ischemic Penumbra
    • Ramos-Cabrer P., Campos F., Sobrino T., et al. Targeting the Ischemic Penumbra. Stroke 2011, 42:7-11.
    • (2011) Stroke , vol.42 , pp. 7-11
    • Ramos-Cabrer, P.1    Campos, F.2    Sobrino, T.3
  • 66
    • 16444379748 scopus 로고    scopus 로고
    • Cerebral small vessel diseases: Cerebral microangiopathies
    • Ringelstein E.B., Nabavi D.G. Cerebral small vessel diseases: Cerebral microangiopathies. Current Opinion in Neurology 2005, 18:179-188.
    • (2005) Current Opinion in Neurology , vol.18 , pp. 179-188
    • Ringelstein, E.B.1    Nabavi, D.G.2
  • 67
    • 33644878711 scopus 로고    scopus 로고
    • Do acute diffusion- and perfusion-weighted MRI lesions identify final infarct volume in ischemic stroke?
    • Rivers C.S., Wardlaw J.M., Armitage P.A., et al. Do acute diffusion- and perfusion-weighted MRI lesions identify final infarct volume in ischemic stroke?. Stroke 2006, 37:98-104.
    • (2006) Stroke , vol.37 , pp. 98-104
    • Rivers, C.S.1    Wardlaw, J.M.2    Armitage, P.A.3
  • 68
    • 0036828345 scopus 로고    scopus 로고
    • Systemic fatty acid responses to transient focal cerebral ischemia: Influence of neuroprotectant therapy with human albumin
    • Rodriguez de Turco E.B., Belayev L., Liu Y., et al. Systemic fatty acid responses to transient focal cerebral ischemia: Influence of neuroprotectant therapy with human albumin. Journal of Neurochemistry 2002, 83:515-524.
    • (2002) Journal of Neurochemistry , vol.83 , pp. 515-524
    • Rodriguez de Turco, E.B.1    Belayev, L.2    Liu, Y.3
  • 69
    • 33645830470 scopus 로고    scopus 로고
    • Toward a multimodal neuroprotective treatment of stroke
    • Rogalewski A., Schneider A., Ringelstein E.B., et al. Toward a multimodal neuroprotective treatment of stroke. Stroke 2006, 37:1129-1136.
    • (2006) Stroke , vol.37 , pp. 1129-1136
    • Rogalewski, A.1    Schneider, A.2    Ringelstein, E.B.3
  • 70
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain: Biology, pathology and therapeutic target
    • Rothwell N.J., Luheshi G.N. Interleukin 1 in the brain: Biology, pathology and therapeutic target. Trends in Neurosciences 2000, 23:618-625.
    • (2000) Trends in Neurosciences , vol.23 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 71
    • 0021359214 scopus 로고
    • Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia
    • Sage J.I., Van Uitert R.L., Duffy T.E. Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia. Stroke 1984, 15:46-50.
    • (1984) Stroke , vol.15 , pp. 46-50
    • Sage, J.I.1    Van Uitert, R.L.2    Duffy, T.E.3
  • 72
    • 53749096762 scopus 로고    scopus 로고
    • Blood-brain barrier tight junction permeability and ischemic stroke
    • Sandoval K.E., Witt K.A. Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiology of Disease 2008, 32:200-219.
    • (2008) Neurobiology of Disease , vol.32 , pp. 200-219
    • Sandoval, K.E.1    Witt, K.A.2
  • 73
    • 0345561549 scopus 로고    scopus 로고
    • Synergistic effects of a combination of low-dose basic fibroblast growth factor and citicoline after temporary experimental focal ischemia
    • Schäbitz W.R., Li F., Irie K., et al. Synergistic effects of a combination of low-dose basic fibroblast growth factor and citicoline after temporary experimental focal ischemia. Stroke 1999, 30:42731.
    • (1999) Stroke , vol.30 , pp. 42731
    • Schäbitz, W.R.1    Li, F.2    Irie, K.3
  • 74
    • 0033596556 scopus 로고    scopus 로고
    • Neuroprotective efficacy of combination therapy with two different antioxidants in rats subjected to transient focal ischemia
    • Schmid-Elsaesser R., Hungerhuber E., Zausinger S., et al. Neuroprotective efficacy of combination therapy with two different antioxidants in rats subjected to transient focal ischemia. Brain Research 1999, 816:471-479.
    • (1999) Brain Research , vol.816 , pp. 471-479
    • Schmid-Elsaesser, R.1    Hungerhuber, E.2    Zausinger, S.3
  • 75
    • 0022510271 scopus 로고
    • The oxidation of arachidonic acid by the cyclooxygenase activity of purified prostaglandin H synthase: Spin trapping of a carbon- centered free radical intermediate
    • Schreiber J., Eling T.E., Mason R.P. The oxidation of arachidonic acid by the cyclooxygenase activity of purified prostaglandin H synthase: Spin trapping of a carbon- centered free radical intermediate. Archives of Biochemistry and Biophysics 1986, 249:126-136.
    • (1986) Archives of Biochemistry and Biophysics , vol.249 , pp. 126-136
    • Schreiber, J.1    Eling, T.E.2    Mason, R.P.3
  • 77
    • 0032889085 scopus 로고    scopus 로고
    • Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia
    • Sheng H., Bart R.D., Oury T.D., et al. Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia. Neuroscience 1999, 88:185-191.
    • (1999) Neuroscience , vol.88 , pp. 185-191
    • Sheng, H.1    Bart, R.D.2    Oury, T.D.3
  • 79
    • 0021743001 scopus 로고
    • Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain
    • Simon R.P., Swan J.H., Meldrum B.S. Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science 1984, 226:850-852.
    • (1984) Science , vol.226 , pp. 850-852
    • Simon, R.P.1    Swan, J.H.2    Meldrum, B.S.3
  • 80
    • 46449123205 scopus 로고    scopus 로고
    • The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
    • Simopoulos A.P. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Experimental Biology and Medicine (Maywood) 2008, 233:674-688.
    • (2008) Experimental Biology and Medicine (Maywood) , vol.233 , pp. 674-688
    • Simopoulos, A.P.1
  • 81
    • 84892360290 scopus 로고    scopus 로고
    • Ischemic Stroke: Basic Pathophysiology and Neuroprotective Strategies
    • Springer-Verlag Berlin Heidelberg, New York
    • Singhal A., Lo E., Dalkara T., et al. Ischemic Stroke: Basic Pathophysiology and Neuroprotective Strategies. Acute ischemic stroke. Part 1 2006, Springer-Verlag Berlin Heidelberg, New York.
    • (2006) Acute ischemic stroke. Part 1
    • Singhal, A.1    Lo, E.2    Dalkara, T.3
  • 82
    • 33747434126 scopus 로고    scopus 로고
    • Safety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part I
    • Smith W.S. Safety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part I. AJNR American Journal of Neuroradiology 2006, 27:1177-1182.
    • (2006) AJNR American Journal of Neuroradiology , vol.27 , pp. 1177-1182
    • Smith, W.S.1
  • 83
    • 0142139346 scopus 로고    scopus 로고
    • Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia
    • Sugawara T., Chan P.H. Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia. Antioxidants & Redox Signaling 2003, 5:597-607.
    • (2003) Antioxidants & Redox Signaling , vol.5 , pp. 597-607
    • Sugawara, T.1    Chan, P.H.2
  • 84
    • 33645822456 scopus 로고    scopus 로고
    • Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons
    • Thomas C.G., Miller A.J., Westbrook G.L. Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons. Journal of Neurophysiology 2006, 95:1727-1734.
    • (2006) Journal of Neurophysiology , vol.95 , pp. 1727-1734
    • Thomas, C.G.1    Miller, A.J.2    Westbrook, G.L.3
  • 85
    • 0031001036 scopus 로고    scopus 로고
    • Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism
    • Trotti D., Rizzini B.L., Rossi D., et al. Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. The European Journal of Neuroscience 1997, 9:1236-1243.
    • (1997) The European Journal of Neuroscience , vol.9 , pp. 1236-1243
    • Trotti, D.1    Rizzini, B.L.2    Rossi, D.3
  • 86
    • 74549173438 scopus 로고    scopus 로고
    • DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke
    • Tu W., Xu X., Peng L., et al. DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke. Cell 2010, 140:222-234.
    • (2010) Cell , vol.140 , pp. 222-234
    • Tu, W.1    Xu, X.2    Peng, L.3
  • 87
    • 0036640251 scopus 로고    scopus 로고
    • Structure and enzymology of a death-associated protein kinase
    • Van Eldik L.J. Structure and enzymology of a death-associated protein kinase. Trends in Pharmacological Sciences 2002, 23:302-304.
    • (2002) Trends in Pharmacological Sciences , vol.23 , pp. 302-304
    • Van Eldik, L.J.1
  • 88
    • 0141542665 scopus 로고    scopus 로고
    • Cdk5 activation induces CA1 pyramidal cell death by direct phosphorylation of NMDA receptors
    • Wang J., Liu S.H., Fu Y.P., et al. Cdk5 activation induces CA1 pyramidal cell death by direct phosphorylation of NMDA receptors. Nature Neuroscience 2003, 6:1039-1047.
    • (2003) Nature Neuroscience , vol.6 , pp. 1039-1047
    • Wang, J.1    Liu, S.H.2    Fu, Y.P.3
  • 89
    • 77958159860 scopus 로고    scopus 로고
    • Docosahexaenoic acid prevents white matter damage after spinal cord injury
    • Ward R.E., Huang W., Curran O.E., et al. Docosahexaenoic acid prevents white matter damage after spinal cord injury. Journal of Neurotrauma 2010, 27:1769-1780.
    • (2010) Journal of Neurotrauma , vol.27 , pp. 1769-1780
    • Ward, R.E.1    Huang, W.2    Curran, O.E.3
  • 90
    • 63249115678 scopus 로고    scopus 로고
    • The blood-brain barrier in brain homeostasis and neurological diseases
    • Weiss N., Miller F., Cazaubon S., et al. The blood-brain barrier in brain homeostasis and neurological diseases. Biochimica et Biophysica Acta 2009, 1788:842-857.
    • (2009) Biochimica et Biophysica Acta , vol.1788 , pp. 842-857
    • Weiss, N.1    Miller, F.2    Cazaubon, S.3
  • 91
    • 0003917278 scopus 로고    scopus 로고
    • Academic Press, San Diego, CA, K.M.A. Welch, L.R. Caplan, D.J. Reis, B.K. Siesjo, B. Weir (Eds.)
    • Primer on cerebrovascular diseases 1997, Academic Press, San Diego, CA. K.M.A. Welch, L.R. Caplan, D.J. Reis, B.K. Siesjo, B. Weir (Eds.).
    • (1997) Primer on cerebrovascular diseases
  • 92
  • 93
    • 4544230902 scopus 로고    scopus 로고
    • Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels
    • Xiong Z.G., Zhu X.M., Chu X.P., Minami M., Hey J., Wei W.L., et al. Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels. Cell 2004, 118:687-698.
    • (2004) Cell , vol.118 , pp. 687-698
    • Xiong, Z.G.1    Zhu, X.M.2    Chu, X.P.3    Minami, M.4    Hey, J.5    Wei, W.L.6
  • 94
    • 79952525006 scopus 로고    scopus 로고
    • Vascular protection and restorative therapy in ischemic stroke
    • Yamashita T., Deguchi K., Nagotani S., et al. Vascular protection and restorative therapy in ischemic stroke. Cell Transplant 2010.
    • (2010) Cell Transplant
    • Yamashita, T.1    Deguchi, K.2    Nagotani, S.3
  • 96
    • 33645536989 scopus 로고    scopus 로고
    • Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator
    • Zhang L., Zhang Z.G., Liu X., et al. Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator. Thrombosis and Haemostasis 2006, 95:166-173.
    • (2006) Thrombosis and Haemostasis , vol.95 , pp. 166-173
    • Zhang, L.1    Zhang, Z.G.2    Liu, X.3
  • 97
    • 0028102479 scopus 로고
    • Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the rat
    • Zhang R.L., Chopp M., Chen H., et al. Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the rat. Journal of Neurological Sciences 1994, 125:3-10.
    • (1994) Journal of Neurological Sciences , vol.125 , pp. 3-10
    • Zhang, R.L.1    Chopp, M.2    Chen, H.3
  • 98
    • 67049165532 scopus 로고    scopus 로고
    • A new mouse model for temporal- and tissue-specific control of extracellular superoxide dismutase
    • Zou Y., Chen C.H., Fike J.R., et al. A new mouse model for temporal- and tissue-specific control of extracellular superoxide dismutase. Genesis 2009, 47:142-154.
    • (2009) Genesis , vol.47 , pp. 142-154
    • Zou, Y.1    Chen, C.H.2    Fike, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.