메뉴 건너뛰기




Volumn 35, Issue 2, 2004, Pages 354-356

tPA and Proteolysis in the Neurovascular Unit

Author keywords

Advances in Stroke; Blood brain barrier; Matrix metalloproteinase; Proteolysis; Reperfusion injury; Tissue plasminogen activator

Indexed keywords

AMYLOID BETA PROTEIN; BETA INTERFERON; EXCITOTOXIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAINIC ACID; LAMININ; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLASMIN; PLASMINOGEN ACTIVATOR; PROTEIN SUBUNIT; PROTEINASE ACTIVATED RECEPTOR 1; SERINE PROTEINASE INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR;

EID: 0842289222     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000115164.80010.8A     Document Type: Short Survey
Times cited : (188)

References (37)
  • 2
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • NINDS rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581-1587.
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 4
    • 0141655037 scopus 로고    scopus 로고
    • Stroke: tPA and the clinic
    • Editorial
    • Marler JR, Goldstein LB. Stroke: tPA and the clinic. Science. 2003;301:1677. Editorial.
    • (2003) Science , vol.301 , pp. 1677
    • Marler, J.R.1    Goldstein, L.B.2
  • 5
    • 0037975705 scopus 로고    scopus 로고
    • Thrombolytic therapy with recombinant tissue plasminogen activator for acute ischemic stroke: Where do we go from here? A cumulative meta-analysis
    • Wardlaw JM, Sandercock PA, Berge E. Thrombolytic therapy with recombinant tissue plasminogen activator for acute ischemic stroke: where do we go from here? A cumulative meta-analysis. Stroke. 2003;34:1437-1442.
    • (2003) Stroke , vol.34 , pp. 1437-1442
    • Wardlaw, J.M.1    Sandercock, P.A.2    Berge, E.3
  • 7
    • 0031951510 scopus 로고    scopus 로고
    • TPA increases neuronal damage after focal cerebral ischemia in wild type and TPA-deficient mice
    • Wang YF, Tsirka SE, Strickland S, Steig PE, Soriano SG, Lipton SA. TPA increases neuronal damage after focal cerebral ischemia in wild type and TPA-deficient mice. Nature Med. 1998;4:228-231.
    • (1998) Nature Med , vol.4 , pp. 228-231
    • Wang, Y.F.1    Tsirka, S.E.2    Strickland, S.3    Steig, P.E.4    Soriano, S.G.5    Lipton, S.A.6
  • 9
    • 0037474052 scopus 로고    scopus 로고
    • Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury
    • Indyk JA, Chen ZL, Tsirka SE, Strickland S. Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury. Neuroscience. 2003;116:359-371.
    • (2003) Neuroscience , vol.116 , pp. 359-371
    • Indyk, J.A.1    Chen, Z.L.2    Tsirka, S.E.3    Strickland, S.4
  • 11
    • 0035405886 scopus 로고    scopus 로고
    • Metalloproteinases in biology and pathology of the nervous system
    • Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci. 2001;2:502-511.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 502-511
    • Yong, V.W.1    Power, C.2    Forsyth, P.3    Edwards, D.R.4
  • 12
    • 0036737795 scopus 로고    scopus 로고
    • Matrix metalloproteinases in neuroinflammation
    • Rosenberg GA. Matrix metalloproteinases in neuroinflammation. Glia. 2002;39:279-291.
    • (2002) Glia , vol.39 , pp. 279-291
    • Rosenberg, G.A.1
  • 13
    • 0035478029 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
    • Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, Fini ME, Lo EH. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci. 2001;21:7724-7732.
    • (2001) J Neurosci , vol.21 , pp. 7724-7732
    • Asahi, M.1    Wang, X.2    Mori, T.3    Sumii, T.4    Jung, J.C.5    Moskowitz, M.A.6    Fini, M.E.7    Lo, E.H.8
  • 14
    • 0842327251 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase in delayed neuronal damage after transient global cerebral ischemia
    • In press
    • Lee SR, Tsuji K, Lee SR, Lo EH. Role of matrix metalloproteinase in delayed neuronal damage after transient global cerebral ischemia. J Neurosci. In press.
    • J Neurosci
    • Lee, S.R.1    Tsuji, K.2    Lee, S.R.3    Lo, E.H.4
  • 15
    • 0036644958 scopus 로고    scopus 로고
    • Extracellular proteolysis in brain injury and inflammation: Role for plasminogen activators and matrix metalloproteinases
    • Lo EH, Wang X, Cuzner ML. Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases. J Neurosci Res. 2002;69:1-9.
    • (2002) J Neurosci Res , vol.69 , pp. 1-9
    • Lo, E.H.1    Wang, X.2    Cuzner, M.L.3
  • 16
    • 0036843258 scopus 로고    scopus 로고
    • Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: Mechanical versus embolic focal ischemia in spontaneously hypertensive rats
    • Aoki T, Sumii T, Mori T, Wang X, Lo EH. Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats. Stroke. 2002;33:2711-2717.
    • (2002) Stroke , vol.33 , pp. 2711-2717
    • Aoki, T.1    Sumii, T.2    Mori, T.3    Wang, X.4    Lo, E.H.5
  • 17
    • 0036195260 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats
    • Sumii T, Lo EH. Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats. Stroke. 2002;33:831-836.
    • (2002) Stroke , vol.33 , pp. 831-836
    • Sumii, T.1    Lo, E.H.2
  • 18
    • 0142137232 scopus 로고    scopus 로고
    • Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator
    • Wang X, Lee SR, Arai K, Lee SR, Tsuji K, Rebeck GW, Lo EH. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med. 2003;9:1313-1317.
    • (2003) Nat Med , vol.9 , pp. 1313-1317
    • Wang, X.1    Lee, S.R.2    Arai, K.3    Lee, S.R.4    Tsuji, K.5    Rebeck, G.W.6    Lo, E.H.7
  • 19
    • 0036585026 scopus 로고    scopus 로고
    • Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II
    • Siao CJ, Tsirka SE. Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II. J Neurosci. 2002;22:3352-3358.
    • (2002) J Neurosci , vol.22 , pp. 3352-3358
    • Siao, C.J.1    Tsirka, S.E.2
  • 20
    • 0036407697 scopus 로고    scopus 로고
    • Reciprocal actions of NCAM and tPA via a Ras-dependent MAPK activation in rat hippocampal neurons
    • Son H, Seuk Kim J, Mogg Kim J, Lee SH, Lee YS. Reciprocal actions of NCAM and tPA via a Ras-dependent MAPK activation in rat hippocampal neurons. Biochem Biophys Res Commun. 2002;298:262-268.
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 262-268
    • Son, H.1    Seuk Kim, J.2    Mogg Kim, J.3    Lee, S.H.4    Lee, Y.S.5
  • 21
    • 0034836428 scopus 로고    scopus 로고
    • LRP: A multifunctional scavenger and signaling receptor
    • Herz J, Strickland DK. LRP: a multifunctional scavenger and signaling receptor. J Clin Invest. 2001;108:779-784.
    • (2001) J Clin Invest , vol.108 , pp. 779-784
    • Herz, J.1    Strickland, D.K.2
  • 22
    • 0345824713 scopus 로고    scopus 로고
    • Tissue type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor related protein
    • Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA. Tissue type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor related protein. J Clin Invest. 2003;112:1533-1540.
    • (2003) J Clin Invest , vol.112 , pp. 1533-1540
    • Yepes, M.1    Sandkvist, M.2    Moore, E.G.3    Bugge, T.H.4    Strickland, D.K.5    Lawrence, D.A.6
  • 23
    • 0037224938 scopus 로고    scopus 로고
    • Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke
    • Castellanos M, Leira R, Serena J, Pumar JM, Lizasoain I, Castillo J, Davalos A. Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke. Stroke. 2003;34:40-46.
    • (2003) Stroke , vol.34 , pp. 40-46
    • Castellanos, M.1    Leira, R.2    Serena, J.3    Pumar, J.M.4    Lizasoain, I.5    Castillo, J.6    Davalos, A.7
  • 24
    • 0041829250 scopus 로고    scopus 로고
    • Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: Influence of different therapies
    • Horstmann S, Kalb P, Koziol J, Gardner H, Wagner S. Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies. Stroke. 2003;34:2165-2170.
    • (2003) Stroke , vol.34 , pp. 2165-2170
    • Horstmann, S.1    Kalb, P.2    Koziol, J.3    Gardner, H.4    Wagner, S.5
  • 26
    • 0037155057 scopus 로고    scopus 로고
    • Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly
    • Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res. 2002;90:251-262.
    • (2002) Circ Res , vol.90 , pp. 251-262
    • Galis, Z.S.1    Khatri, J.J.2
  • 27
    • 0033807117 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Not-so-innocent bystanders in heart failure
    • Lee RT, Libby P. Matrix metalloproteinases: not-so-innocent bystanders in heart failure. J Clin Invest. 2000;106:827-828.
    • (2000) J Clin Invest , vol.106 , pp. 827-828
    • Lee, R.T.1    Libby, P.2
  • 28
    • 0042623437 scopus 로고    scopus 로고
    • Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion
    • Pfefferkon T, Rosenberg GA. Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion. Stroke. 2003;34:2025-2030.
    • (2003) Stroke , vol.34 , pp. 2025-2030
    • Pfefferkon, T.1    Rosenberg, G.A.2
  • 30
    • 0037031298 scopus 로고    scopus 로고
    • Adjuvant treatment with neuroserpin increases the therapeutic window for tPA administration in a rat model of embolic stroke
    • Zhang L, Zhang L, Yepes M, Jiang Q, Li Q, Amiego P, Coleman TA, Lawrence DA, Chopp M. Adjuvant treatment with neuroserpin increases the therapeutic window for tPA administration in a rat model of embolic stroke. Circulation. 2002;106:740-745.
    • (2002) Circulation , vol.106 , pp. 740-745
    • Zhang, L.1    Zhang, L.2    Yepes, M.3    Jiang, Q.4    Li, Q.5    Amiego, P.6    Coleman, T.A.7    Lawrence, D.A.8    Chopp, M.9
  • 31
    • 0036712353 scopus 로고    scopus 로고
    • Microplasmin: A novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits
    • Lapchak PA, Arujo DM, Pakola S, Song D, Wei J, Zivin JA. Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits. Stroke. 2002;33:2279-2284.
    • (2002) Stroke , vol.33 , pp. 2279-2284
    • Lapchak, P.A.1    Arujo, D.M.2    Pakola, S.3    Song, D.4    Wei, J.5    Zivin, J.A.6
  • 32
    • 0037321482 scopus 로고    scopus 로고
    • Vampire bat salivary plasminogen activator (desmoteplase): A unique fibrinolytic enzyme that does not promote neurodegeneration
    • Liberatore GT, Samson A, Bladin C, Schleuning WD, Medcalf RL. Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration. Stroke. 2003;34:537-543.
    • (2003) Stroke , vol.34 , pp. 537-543
    • Liberatore, G.T.1    Samson, A.2    Bladin, C.3    Schleuning, W.D.4    Medcalf, R.L.5
  • 33
    • 0043071539 scopus 로고    scopus 로고
    • Cerebral microvessel responses to focal ischemia
    • del Zoppo GJ, Mabuchi T. Cerebral microvessel responses to focal ischemia. J Cereb Blood Flow Metab. 2003;23:879-894.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 879-894
    • Del Zoppo, G.J.1    Mabuchi, T.2
  • 34
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci. 2003;4:399-415.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 35
    • 0041835847 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy
    • Lee JM, Yin KJ, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J. Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy. Ann Neurol. 2003;54:379-382.
    • (2003) Ann Neurol , vol.54 , pp. 379-382
    • Lee, J.M.1    Yin, K.J.2    Hsin, I.3    Chen, S.4    Fryer, J.D.5    Holtzman, D.M.6    Hsu, C.Y.7    Xu, J.8
  • 36
    • 0038241040 scopus 로고    scopus 로고
    • Pathogenic beta-amyloid induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells
    • Jung SS, Zhang W, van Nostrand WE. Pathogenic beta-amyloid induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells. J Neurochem. 2003;85:1208-1215.
    • (2003) J Neurochem , vol.85 , pp. 1208-1215
    • Jung, S.S.1    Zhang, W.2    Van Nostrand, W.E.3
  • 37
    • 0037928427 scopus 로고    scopus 로고
    • Amyloid beta protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells
    • Davis J, Wagner MR, Zhang W, Xu F, van Nostrand WE. Amyloid beta protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells. J Biol Chem. 2003;278:19054-19061.
    • (2003) J Biol Chem , vol.278 , pp. 19054-19061
    • Davis, J.1    Wagner, M.R.2    Zhang, W.3    Xu, F.4    Van Nostrand, W.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.