Structure and enzymology of a death-associated protein kinase

Trends in Pharmacological Sciences

Volumn 23, Issue 7, 2002, Pages 302-304

  Van Eldik, Linda J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEATH ASSOCIATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; CANCER INHIBITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEOMICS; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 0036640251     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(02)02049-7     Document Type: Review

References (11)

1. Identification of a novel serine/threonine kinase and a novel 15 kD protein as potential mediators of the gamma interferon-induced cell death
2. DAP-kinase: From functional gene cloning to establishment of its role in apoptosis and cancer
3. The DAP kinase family of pro-apoptotic proteins: Novel players in the apoptotic game
4. Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons
5. DAP kinase activity is critical for C2-ceramide-induced apoptosis in PC12 cells
6. TGFβ induces apoptosis through Smad-mediated expression of DAP-kinase
7. Identification of a new form of death-associated protein kinase that promotes cell survival
8. Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression
9. A protein kinase associated with apoptosis and tumor suppression. Structure, activity, and discovery of peptide substrates
10. Calmodulin-regulated protein kinases
11. The pro-apoptotic function of death-associated protein kinase is controlled by a unique autophosphorylation-based mechanism