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Volumn 28, Issue 6, 2012, Pages 2188-2194

Novel anti-angiogenic effects of formononetin in human colon cancer cells and tumor xenograft

Author keywords

Angiogenesis; Cell invasiveness; Cell proliferation; Colon cancer; Formononetin

Indexed keywords

ANGIOGENIC FACTOR; DIMETHYL SULFOXIDE; FORMONONETIN; MATRIX METALLOPROTEINASE; VASCULOTROPIN;

EID: 84868143700     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2056     Document Type: Conference Paper
Times cited : (66)

References (48)
  • 1
    • 0346117570 scopus 로고    scopus 로고
    • Recent insights into angiogenesis, apoptosis, invasion, and metastasis in colorectal carcinoma
    • DOI 10.1245/ASO.2003.02.021
    • Boedefeld WM, Bland KI and Heslin MJ: Recent insights into angiogenesis, apoptosis, invasion, and metastasis in colorectal carcinoma. Ann Surg Oncol 10:839-851, 2003. (Pubitemid 40486847)
    • (2003) Annals of Surgical Oncology , vol.10 , Issue.8 , pp. 839-851
    • Boedefeld II, W.M.1    Bland, K.I.2    Heslin, M.J.3
  • 2
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M and Werb Z: New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2:161-174, 2002. (Pubitemid 37328786)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.3 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 3
    • 0142117232 scopus 로고    scopus 로고
    • Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients
    • DOI 10.1002/ijc.11436
    • Tutton MG, George ML, Eccles SA, Burton S, Swift RI and Abulafi AM: Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients. Int J Cancer 107:541-550, 2003. (Pubitemid 37296113)
    • (2003) International Journal of Cancer , vol.107 , Issue.4 , pp. 541-550
    • Tutton, M.G.1    George, M.L.2    Eccles, S.A.3    Burton, S.4    Swift, R.I.5    Abulafi, A.M.6
  • 5
    • 0027054303 scopus 로고
    • Shi-Quan-Da-Bu-Tang (Ten Significant Tonic Decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs
    • Zee-Cheng RK: Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifer in cancer immunotherapy, potentiation and detoxifcation of anticancer drugs. Methods Find Exp Clin Pharmacol 14:725-736, 1992. (Pubitemid 23057193)
    • (1992) Methods and Findings in Experimental and Clinical Pharmacology , vol.14 , Issue.9 , pp. 725-736
    • Zee-Cheng, R.K.-Y.1
  • 6
    • 3142684519 scopus 로고    scopus 로고
    • A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb
    • DOI 10.1016/j.bbrc.2004.06.065, PII S0006291X04013129
    • Shao BM, Xu W, Dai H, Tu P, Li Z and Gao XM: A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem Biochem Biophys Res Commun 320:1103-1111, 2004. (Pubitemid 38916657)
    • (2004) Biochemical and Biophysical Research Communications , vol.320 , Issue.4 , pp. 1103-1111
    • Shao, B.-M.1    Xu, W.2    Dai, H.3    Tu, P.4    Li, Z.5    Gao, X.-M.6
  • 7
    • 0038544012 scopus 로고    scopus 로고
    • Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor
    • In Chinese
    • Duan P and Wang ZM: Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor. Zhongguo Zhong Xi Yi Jie He Za Zhi 22:515-517, 2002 (In Chinese).
    • (2002) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.22 , pp. 515-517
    • Duan, P.1    Wang, Z.M.2
  • 8
    • 34447345960 scopus 로고    scopus 로고
    • Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft
    • DOI 10.1093/carcin/bgl238
    • Tin MM, Cho CH, Chan K, James AE and Ko JK: Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft. Carcinogenesis 28:1347-1355, 2007. (Pubitemid 47062696)
    • (2007) Carcinogenesis , vol.28 , Issue.6 , pp. 1347-1355
    • Tin, M.M.Y.1    Cho, C.2    Chan, K.3    James, A.E.4    Ko, J.K.S.5
  • 9
    • 67650082647 scopus 로고    scopus 로고
    • A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene
    • Auyeung KK, Cho CH and Ko JK: A novel anticancer effect of Astragalus saponins: transcriptional activation of NSAID-activated gene. Int J Cancer 125:1082-1091, 2009.
    • (2009) Int J Cancer , vol.125 , pp. 1082-1091
    • Auyeung, K.K.1    Cho, C.H.2    Ko, J.K.3
  • 10
    • 33645512781 scopus 로고    scopus 로고
    • Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro
    • Shen P, Liu MH, Ng TY, Chan YH and Yong EL: Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro. J Nutr 136:899-905, 2006.
    • (2006) J Nutr , vol.136 , pp. 899-905
    • Shen, P.1    Liu, M.H.2    Ng, T.Y.3    Chan, Y.H.4    Yong, E.L.5
  • 11
    • 0030959281 scopus 로고    scopus 로고
    • Antioxidant constituents from licorice roots: Isolation, structure elucidation and antioxidant capacity toward LDL oxidation
    • Vaya J, Belinky PA and Aviram M: Antioxidant constituents from licorice roots: isolation, structure elucidation and antioxidant capacity toward LDL oxidation. Free Rad Biol Med 23:302-312, 1997.
    • (1997) Free Rad Biol Med , vol.23 , pp. 302-312
    • Vaya, J.1    Belinky, P.A.2    Aviram, M.3
  • 12
    • 23944514993 scopus 로고    scopus 로고
    • Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity
    • DOI 10.1111/j.1365-2567.2005.02199.x
    • Park J, Kim SH, Cho D and Kim TS: Formononetin, a phytooestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity. Immunology 116:71-81, 2005. (Pubitemid 41208354)
    • (2005) Immunology , vol.116 , Issue.1 , pp. 71-81
    • Park, J.1    Kim, S.H.2    Cho, D.3    Kim, T.S.4
  • 13
    • 29344443799 scopus 로고    scopus 로고
    • Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isoflavones in murine macrophages
    • DOI 10.1002/mnfr.200500103
    • Jun. M, Hong J, Jeong WS and Ho CT: Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isofavones in murine macrophages. Mol Nutr Food Res 49:1154-1159, 2005. (Pubitemid 43004348)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.12 , pp. 1154-1159
    • Jun, M.1    Hong, J.2    Jeong, W.-S.3    Ho, C.-T.4
  • 14
    • 34247176729 scopus 로고    scopus 로고
    • An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women
    • DOI 10.1016/j.atherosclerosis.2006.04.033, PII S0021915006002528
    • Nestel P, Fujii A and Zhang L: An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women. Atherosclerosis 192:184-189, 2007. (Pubitemid 46602296)
    • (2007) Atherosclerosis , vol.192 , Issue.1 , pp. 184-189
    • Nestel, P.1    Fujii, A.2    Zhang, L.3
  • 15
    • 33846385060 scopus 로고    scopus 로고
    • Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds
    • DOI 10.1016/j.phymed.2006.03.008, PII S0944711306000675
    • Huo Y, Guo C, Zhang QY, Chen WS, Zheng HC, Rahman K and Qin LP: Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds. Phytomedicine 14:143-146, 2007. (Pubitemid 46136947)
    • (2007) Phytomedicine , vol.14 , Issue.2-3 , pp. 143-146
    • Huo, Y.1    Guo, C.2    Zhang, Q.-Y.3    Chen, W.-S.4    Zheng, H.-C.5    Rahman, K.6    Qin, L.-P.7
  • 16
    • 33645960959 scopus 로고    scopus 로고
    • Chemical and biological assessment of a chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: Determination of drug ratio in having optimized properties
    • Dong TTX, Zhao KJ, Gao QT, et al: Chemical and biological assessment of a chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: determination of drug ratio in having optimized properties. J Agric Food Chem 54:2767-2774, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 2767-2774
    • Dong, T.T.X.1    Zhao, K.J.2    Gao, Q.T.3
  • 17
    • 33847069296 scopus 로고    scopus 로고
    • Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene
    • DOI 10.1016/j.ejphar.2006.12.004, PII S0014299906013860
    • Auyeung KK and Ko JK: Novel herbal flavonoids promote apoptosis but differentially induce cell cycle arrest in human colon cancer cell. Invest New Drugs 28:1-13, 2010. (Pubitemid 46274648)
    • (2007) European Journal of Pharmacology , vol.559 , Issue.1 , pp. 1-13
    • Ko, J.K.S.1    Leung, W.C.2    Ho, W.K.3    Chiu, P.4
  • 18
    • 0023187867 scopus 로고
    • A rapid in vitro assay for quantitating the invasive potential of tumor cells
    • Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aaronson SA, Kozlowski JM and McEwan RN: A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47:3239-3245, 1987. (Pubitemid 17082655)
    • (1987) Cancer Research , vol.47 , Issue.12 , pp. 3239-3245
    • Albini, A.1    Iwamoto, Y.2    Kleinman, H.K.3
  • 19
    • 64749091010 scopus 로고    scopus 로고
    • Astragalus saponins induce apoptosis via an ERK-independent NF-κB signaling pathway in the human hepatocellular HepG2 cell line
    • Auyeung KK, Law PC and Ko JK: Astragalus saponins induce apoptosis via an ERK-independent NF-κB signaling pathway in the human hepatocellular HepG2 cell line. Int J Mol Med 23:189-196, 2009.
    • (2009) Int J Mol Med , vol.23 , pp. 189-196
    • Auyeung, K.K.1    Law, P.C.2    Ko, J.K.3
  • 20
    • 27944473098 scopus 로고    scopus 로고
    • Amelioration of experimental colitis by Astragalus membranaceus through antioxidation and inhibition of adhesion molecule synthesis
    • Ko JKS, Lam FYL and Cheung APL: Amelioration of experimental colitis by Astragalus membranaceus through antioxidation and inhibition of adhesion molecule synthesis. World J Gastroenterol 11:5787-5794, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 5787-5794
    • Ko, J.K.S.1    Lam, F.Y.L.2    Cheung, A.P.L.3
  • 21
    • 0033963827 scopus 로고    scopus 로고
    • Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line
    • Kondo Y, Arii S, Mori A, Furutani M, Chiba T and Imamura M: Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line. Clin Cancer Res 6:622-630, 2000. (Pubitemid 30111488)
    • (2000) Clinical Cancer Research , vol.6 , Issue.2 , pp. 622-630
    • Kondo, Y.1    Arii, S.2    Mori, A.3    Furutani, M.4    Chiba, T.5    Imamura, M.6
  • 22
    • 44649108424 scopus 로고    scopus 로고
    • A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer
    • DOI 10.1053/j.gastro.2008.02.095, PII S0016508508004320
    • Sukhthankar M, Yamaguchi K, Lee SH, McEntee MF, Eling TE, Hara Y and Baek SJ: A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer. Gastroenterology 134:1972-1980, 2008. (Pubitemid 351783262)
    • (2008) Gastroenterology , vol.134 , Issue.7 , pp. 1972-1980
    • Sukhthankar, M.1    Yamaguchi, K.2    Lee, S.3    McEntee, M.F.4    Eling, T.E.5    Hara, Y.6    Baek, S.J.7
  • 23
    • 0033767854 scopus 로고    scopus 로고
    • Phytoestrogens as hormone replacement therapy: An evidence-based approach
    • Carusi D: Phytoestrogens as hormone replacement therapy: an evidence-based approach. Prim Care Update Ob Gyns 7:253-259, 2000.
    • (2000) Prim Care Update Ob Gyns , vol.7 , pp. 253-259
    • Carusi, D.1
  • 24
    • 33644863498 scopus 로고    scopus 로고
    • Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF
    • Liang WC, Wu X, Peale FV, Lee C V, et al: Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF. J Biol Chem 28:951-961, 2006.
    • (2006) J Biol Chem , vol.28 , pp. 951-961
    • Liang, W.C.1    Wu, X.2    Peale, F.V.3    Lee, C.V.4
  • 25
    • 0034799329 scopus 로고    scopus 로고
    • The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency
    • Arjmandi BH: The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. J Am Coll Nutr 20:S398-S402, 2001.
    • (2001) J Am Coll Nutr , vol.20
    • Arjmandi, B.H.1
  • 27
    • 0027373686 scopus 로고
    • Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract
    • Yanagihara K, Ito A, Toge T and Numoto M: Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract. Cancer Res 3:5815-5821, 1993. (Pubitemid 23360293)
    • (1993) Cancer Research , vol.53 , Issue.23 , pp. 5815-5821
    • Yanagihara, K.1    Ito, A.2    Toge, T.3    Numoto, M.4
  • 28
    • 18144411278 scopus 로고    scopus 로고
    • Phytoestrogens derived from red clover: An alternative to estrogen replacement therapy?
    • DOI 10.1016/j.jsbmb.2004.12.038, PII S0960076005000658
    • Beck V, Rohr U and Jungbauer A: Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy? J Steroid Biochem Mol Biol 94:499-518, 2005. (Pubitemid 40616410)
    • (2005) Journal of Steroid Biochemistry and Molecular Biology , vol.94 , Issue.5 , pp. 499-518
    • Beck, V.1    Rohr, U.2    Jungbauer, A.3
  • 29
    • 2442447195 scopus 로고    scopus 로고
    • Angiogenesis as a new target for cancer control
    • DOI 10.1016/S1359-6349(03)00007-7, PII S1359634903000077
    • Harris AL: Angiogenesis as a new target for cancer control. Eur J Cancer Suppl 1:1-12, 2003. (Pubitemid 38624426)
    • (2003) European Journal of Cancer, Supplement , vol.1 , Issue.2 , pp. 1-12
    • Harris, A.L.1
  • 31
    • 0030512608 scopus 로고    scopus 로고
    • Transgenic mouse models of tumour angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models
    • Hanahan D, Christofori G, Naik P and Arbeit J: Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models. Eur J Cancer 32 A: 2386-2393, 1996.
    • (1996) Eur J Cancer , vol.32 A , pp. 2386-2393
    • Hanahan, D.1    Christofori, G.2    Naik, P.3    Arbeit, J.4
  • 32
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • DOI 10.1016/S0092-8674(00)80108-7
    • Hanahan D and Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86:353-364, 1996. (Pubitemid 26272076)
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 33
    • 0030037264 scopus 로고    scopus 로고
    • Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma
    • DOI 10.1002/(SICI)1097-0142(19960715)78:2<226::AID-CNCR6>3.0.CO;2-J
    • Takebayashi Y, Aklyama S, Yamada K, Akiba S and Aikou T: Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma. Cancer 78:226-231, 1996. (Pubitemid 26234563)
    • (1996) Cancer , vol.78 , Issue.2 , pp. 226-231
    • Takebayashi, Y.1    Akiyama, S.-I.2    Yamada, K.3    Akiba, S.4    Aikou, T.5
  • 35
    • 0345008956 scopus 로고    scopus 로고
    • Molecular determinants of colon cancer metastasis
    • Portera CA Jr, Berman RS and Ellis LM: Molecular determinants of colon cancer metastasis. Surg Oncol 7:183-195, 1998.
    • (1998) Surg Oncol , vol.7 , pp. 183-195
    • Portera Jr., C.A.1    Berman, R.S.2    Ellis, L.M.3
  • 36
    • 0029011882 scopus 로고
    • Biology of human colon cancer metastasis
    • Gutman M and Fidler IJ: Biology of human colon cancer metastasis. World J Surg 19:226-234, 1995.
    • (1995) World J Surg , vol.19 , pp. 226-234
    • Gutman, M.1    Fidler, I.J.2
  • 38
    • 0022308404 scopus 로고
    • Mechanisms of tumor invasion: Evidence from in vivo observations
    • Gabbert H: Mechanisms of tumor invasion: evidence from in vivo observations. Cancer Metastasis Rev 4:293-309, 1985.
    • (1985) Cancer Metastasis Rev , vol.4 , pp. 293-309
    • Gabbert, H.1
  • 39
    • 0242658826 scopus 로고    scopus 로고
    • A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity
    • DOI 10.1038/sj.cgt.7700642
    • London CA, Sekhon HS, Arora V, Stein DA, Iversen PL and Devi GR: A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. Cancer Gene Ther 10:823-832, 2003. (Pubitemid 37420041)
    • (2003) Cancer Gene Therapy , vol.10 , Issue.11 , pp. 823-832
    • London, C.A.1    Sekhon, H.S.2    Arora, V.3    Stein, D.A.4    Iversen, P.L.5    Devi, G.R.6
  • 41
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • DOI 10.1126/science.1067100
    • Coussens LM, Fingleton B and Matrisian LM: Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295:2387-2392, 2002. (Pubitemid 34270240)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 42
  • 43
    • 65949117911 scopus 로고    scopus 로고
    • Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis
    • Zuzga D, Gibbons AV and Li P: Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis. Clin Transl Sci 1:136-141, 2008.
    • (2008) Clin Transl Sci , vol.1 , pp. 136-141
    • Zuzga, D.1    Gibbons, A.V.2    Li, P.3
  • 44
    • 33645669923 scopus 로고    scopus 로고
    • Tumor epithelial cell matrix metalloproteinase-9 is a target for antimetastatic therapy in colorectal cancer
    • Lubbe WJ, Zhou ZY, Fu W, et al: Tumor epithelial cell matrix metalloproteinase-9 is a target for antimetastatic therapy in colorectal cancer. Clin Cancer Res 12:1876-1882, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 1876-1882
    • Lubbe, W.J.1    Zhou, Z.Y.2    Fu, W.3
  • 45
    • 0032850365 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumour invasion and metastasis
    • DOI 10.1002/(SICI)1096-9896(199911)189:3<300::AID-PATH456>3.0.CO;2- C
    • Curran S and Murray GI: Matrix metalloproteinases in tumour invasion and metastasis. J Pathol 189:300-308, 1999. (Pubitemid 29489213)
    • (1999) Journal of Pathology , vol.189 , Issue.3 , pp. 300-308
    • Curran, S.1    Murray, G.I.2
  • 46
    • 65949108601 scopus 로고    scopus 로고
    • Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9
    • Lubbe WJ, Zuzga DS, Zhou ZY, et al: Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9. Cancer Res 69:5472-5476, 2009.
    • (2009) Cancer Res , vol.69 , pp. 5472-5476
    • Lubbe, W.J.1    Zuzga, D.S.2    Zhou, Z.Y.3
  • 47
    • 34250333704 scopus 로고    scopus 로고
    • INK4a and mitogen-activated protein kinase pathway
    • DOI 10.1158/0008-5472.CAN-07-0380
    • Rao JS, Bhoopathi P, Chetty C, Gujrati M and Lakka SS: MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16 (INK4a) and mitogen-activated protein kinase pathway. Cancer Res 67:4956-4964, 2007. (Pubitemid 46910204)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4956-4964
    • Rao, J.S.1    Bhoopathi, P.2    Chetty, C.3    Gujrati, M.4    Lakka, S.S.5
  • 48
    • 38349175935 scopus 로고    scopus 로고
    • Blockade of tumor growth due to MMP-9 inhibition is mediated by sequential activation of β1 integrin, ERK and NFκB
    • Bhoopathi P, Chetty C, Kunigal S, Vanamala SK, Rao JS and Lakka SS: Blockade of tumor growth due to MMP-9 inhibition is mediated by sequential activation of β1 integrin, ERK and NFκB. J Biol Chem 283:1545-1552, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 1545-1552
    • Bhoopathi, P.1    Chetty, C.2    Kunigal, S.3    Vanamala, S.K.4    Rao, J.S.5    Lakka, S.S.6


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