Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF

Journal of Biological Chemistry

Volumn 281, Issue 2, 2006, Pages 951-961

  Liang, Wei Ching ^a   Wu, Xiumin ^a   Peale, Franklin V ^a   Lee, Chingwei V ^a   Meng, Y Gloria ^a   Gutierrez, Johnny ^a   Fu, Ling ^a   Malik, Ajay K ^a,b   Gerber, Hans Peter ^a   Ferrara, Napoleone ^a   Fuh, Germaine ^a  

^a GENENTECH INC   (United States)

^b Hollis Eden Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOMEDICAL ENGINEERING; DISEASES; GENES; TUMORS;

ANTI-VEGF ANTIBODIES; HUMAN TUMOR XENOGRAFTS; TUMOR XENOGRAFTS; VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF);

ANTIBODIES;

BEVACIZUMAB; VASCULOTROPIN ANTIBODY; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY; VASCULOTROPIN A;

ARTICLE; ENDOTHELIUM CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SKELETAL MUSCLE; STROMA CELL; TUMOR XENOGRAFT; UMBILICAL VEIN; AMINO ACID SEQUENCE; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; CHEMISTRY; CYTOLOGY; DISEASE COURSE; DISEASE MODEL; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; KINETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PROTEIN BINDING; SPECIES DIFFERENCE; TUMOR CELL LINE; VASCULAR ENDOTHELIUM;

MURINAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; KINETICS; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE LIBRARY; PROTEIN BINDING; SPECIES SPECIFICITY; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33644863498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508199200     Document Type: Article

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