The Role of Phytoestrogens in the Prevention and Treatment of Osteoporosis in Ovarian Hormone Deficiency

Journal of the American College of Nutrition

Volumn 20, Issue , 2001, Pages 398S-402S

  Arjmandi, Bahram H ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Dried plums; Flaxseed; Isoflavones; Osteoporosis; Soy protein

Indexed keywords

HORMONE; ISOFLAVONE DERIVATIVE; LIGNAN; PHYTOESTROGEN;

ADULT; BONE ATROPHY; CANCER; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FRACTURE; HIP FRACTURE; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; MAJOR CLINICAL STUDY; OSTEOPOROSIS; POSTMENOPAUSE; RISK FACTOR; SOYBEAN; TREATMENT PLANNING;

ANIMALS; BONE DENSITY; COMPLEMENTARY THERAPIES; ESTROGEN REPLACEMENT THERAPY; ESTROGENS, NON-STEROIDAL; FEMALE; FLAX; HUMANS; ISOFLAVONES; MALE; OSTEOPOROSIS, POSTMENOPAUSAL; PHYTOESTROGENS; PLANT PREPARATIONS; POSTMENOPAUSE; RATS; RISK FACTORS; SEEDS; SOYBEANS; TREATMENT OUTCOME;

EID: 0034799329     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2001.10719175     Document Type: Article

References (31)

1. Dempster DW, Lindsay R: Pathogenesis of osteoporosis. Lancet 341: 797-801, 1996.
2. Bonnic SL: AMWA position statement on osteoporosis. J Am Med Women Assoc 45: 75-79, 1990.
3. Mundy GR: Visions for the future in osteoporosis research. Osteoporos Int 2(Suppl): 29S-34S, 1993.
4. Tolstoi LG, Levin RM: Osteoporosis the treatment controversy. Nutr Today 27: 6-12, 1992.
5. Johannes CB, Crawford SL, Posner JG, McKinlay SM: Longitudinal patterns and correlates of hormone replacement therapy use in middle-aged women. Am J Epidemiol 140: 439-452, 1994.
6. Cosman F, Lindsay R: Selective estrogen receptor modulators: Clinical spectrum. Endocr Rev 20: 418-434, 1999.
7. Brzezinski A, Debi A: Phytoestrogens: the “natural” selective estrogen receptor modulators. Eu J Obstet Gynecol Rep Biol 85: 47-51, 1999.
8. Kalu DN, Masoro EJ, Byung PY, Hardin RR, Hollis BW: Modulation of age-related hyperparathyroidism and senile bone loss in Fischer rats by soy protein and food restriction. Endocrinology 122: 1847-1854, 1988.
9. Omi N, Aoi S, Ezawa I: Evaluation of effect of soybean milk and soybean milk peptide on bone metabolism in the rat model with ovariectomized osteoporosis. J Nutri Sci Vitaminol 40: 201-211, 1994.
10. Arjmandi BH, Alekel L, Hollis BW, Amin D, Stacewicz-Sapuntzakis M, Gou P, Kukreja SC: Dietary soy protein prevents bone loss in an ovariectomized rat model of osteoporosis. J Nutr 126: 161-167, 1996.
11. Harrison E, Adjei A, Ameho C, Yamamoto S, Kono S: The effect of soybean protein on bone loss in a rat model of postmenopausal osteoporosis. J Nutr Sci Vitaminol Tokyo 44: 257-268, 1998.
12. Fanti O, Monier-Faugere Z, Geng Z, Schmidt GJ, Morris PE, Cohen D, Malluche HH: The phytoestrogen genistein reduces bone loss in short-term ovariectomized rats. Osteoporos Int 8: 274-281, 1998.
13. Arjmandi BH, Getlinger MJ, Goyal NV, Alekel L, Hasler CM, Juma S, Drum ML, Kukreja SC: The role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone deficiency in rats. Am J Clin Nutr 68(Suppl): 1358S-1363S, 1998.
14. Anderson JJ, Ambrose WW, Garner SC: Biphasic effects of genistein on bone tissue in the ovariectomized, lactating rat model. Proc Soc Exp Biol Med 217: 345-350, 1998.
15. Picherit C, Coxam V, Bennetau-Pelissero C, Kati-Coulibaly S, Davicco MJ, Lebecque P, Barlet JP: Daidzein is more efficient than genistein in preventing ovariectomy-induced bone loss in rats. J Nutr 130: 1675-1681, 2000.
16. Potter SM, Baum JA, Teng H, Stillman RJ, Shay NF, Erdman JW: Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am J Clin Nutr 68: 1375S-1379S, 1998.
17. Alekel DL, St Germain A, Peterson C, Hanson K, Stewart JW, Toda T: Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr 72: 844-852, 2000.
18. Wangen KE, Duncan AM, Merz-Demlow BE, Xu X, Marcus R, Phipps WR, Kurzer MS: Effects of soy isoflavones on markers of bone turnover in premenopausal and postmenopausal women. J Clin Endocrinol Metab 85: 3043-3048, 2000.
19. Scheiber MD, Liu JH, Subbiah MTR, Rebar RW, Setchell KDR: Dietary soy isoflavones favorably influence lipids and bone turnover in healthy postmenopausal women. Third International Symposium on the Role of Soy in Preventing and Treating Chronic Disease, Washington, DC, October, pp 18-19, 1999 [Abstract].
20. Ayers DC, Loike JU: “Lignans: Chemical, Biological, and Clinical Properties.” Cambridge: Cambridge University Press, 1990.
21. Turner RT, Wakley GK, Hannon KS, Bell NH: Tamoxifen inhibits osteoclast mediated resorption of trabecular bone in ovarian hormone-deficient rats. Endocrinology 122: 1146-1150, 1988.
22. Jeffery NM, Sanderson P, Sherrington EJ, Newsholme EA, Calder PC: The ratio of n-6 to n-3 polyunsaturated fatty acids in the rat diet alters serum lipid levels and lymphocyte functions. Lipid 31: 737-745, 1996.
23. Tashjian AH, Voelkel EF, Levine L, Goldhaber P: Evidence that the bone resorption-stimulating factor produced by mouse fibrosarcoma cells is prostaglandin E2: A new model for the hypercalcemia of cancer. J Exp Med 136: 1329-1343, 1972.
24. Arjmandi BH, Juma S, Lucas EA, Wei L, Venkatesh S, Khan DA. Flaxseed supplementation positively influence bone metabolism in postmenopausal women. JANA 1: 27-32, 1998.
25. Donovan JL, Meyer AS, Waterhouse AL: Phenolic composition and antioxidant activity of prunes and prune juice (Prunus domestica). J Agri Food Chem 46: 1247-1252, 1998.
26. Lucas EA, Juma S, Stoecker BJ, Arjmandi BH: Prune suppresses ovariectomy-induced hypercholesterolemia in rats. J Nutr Biochem 11: 255-259, 2000.
27. Nielsen FH, Hunt CD, Mullen LM, Hunt JR: Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1: 394-397, 1987.
28. Derher I, Schutze N, Baur A, Hesse K, Schneider D, Kohrle J, Jakob F: Selenoproteins are expressed in fetal human osteoblastlike cells. Biochem Biophys Res Commun 245: 101-107, 1998.
29. Volpe SL, Taper JL, Meacham S: The relationship between boron and magnesium status and bone mineral density in the human: a review. Magnesium Res 6: 291-296, 1993.
30. Arjmandi BH, Lucas EA, Juma S, Soliman A, Stoecker BJ, Khalil DA, Smith BJ, Wang C: Prune prevents ovariectomy-induced bone loss in rats. JANA 4: 50-56, 2001.
31. Deyhim F, Lucas EA, Brusewitz G, Stoecker BJ, Arjmandi BH: Prune dose-dependently reverses bone loss in ovarian hormone deficient rats. JBMR 14: 394S, 1999 [Abstract].