Astragalus saponins induce apoptosis via an ERK-independent NF-κB signaling pathway in the human hepatocellular HepG2 cell line

International Journal of Molecular Medicine

Volumn 23, Issue 2, 2009, Pages 189-196

  Auyeung, Kathy Ka Wai ^a   Law, Pui Ching ^a   Ko, Joshua Ka Shun ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Apoptosis; Astragalus saponin; Extracellular signal regulated protein kinase; HepG2 cells; Nuclear factor B

Indexed keywords

ALPHA FETOPROTEIN; CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL 2; PROTEIN BCL XL; SAPONIN; INDUCIBLE NITRIC OXIDE SYNTHASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTRAGALUS PLANT; CELL STRAIN HEPG2; CHROMATIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CHEMISTRY; GENETICS; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; TUMOR CELL LINE;

ALPHA-FETOPROTEINS; APOPTOSIS; ASTRAGALUS PLANT; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIVER NEOPLASMS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; SAPONINS; SIGNAL TRANSDUCTION;

EID: 64749091010     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000116     Document Type: Article

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