A novel anticancer effect of Astragalus saponins: Transcriptional activation of NSAID-activated gene

International Journal of Cancer

Volumn 125, Issue 5, 2009, Pages 1082-1091

  Auyeung, Kathy K W ^a   Cho, Chi Hin ^b   Ko, Joshua K S ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b Chinese University of Hong Kong   (Hong Kong)

Author keywords

Apoptosis; Astragalus saponins; Chemotherapy; NAG 1; PI3K Akt inhibitors

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ASTRAGALUS EXTRACT; EARLY GROWTH RESPONSE FACTOR 1; ETOPOSIDE; HOE 33342; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; SAPONIN DERIVATIVE; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG DNA BINDING; GENE; GENE ACTIVATION; HUMAN; HUMAN CELL; NAG 1 GENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; ASTRAGALUS PLANT; BLOTTING, WESTERN; EARLY GROWTH RESPONSE PROTEIN 1; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; LUCIFERASES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SAPONINS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 67650082647     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24397     Document Type: Article

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