Activity-Based Protein Profiling Reveals Mitochondrial Oxidative Enzyme Impairment and Restoration in Diet-Induced Obese Mice

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Sadler, Natalie C ^a   Angel, Thomas E ^a   Lewis, Michael P ^a   Pederson, LeeAnna M ^a   Chauvigné Hines, Lacie M ^a   Wiedner, Susan D ^a   Zink, Erika M ^a   Smith, Richard D ^a   Wright, Aaron T ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MITOCHONDRIAL ENZYME; NUCLEOTIDE BINDING PROTEIN; OXIDOREDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME DEFECT; FATTY ACID OXIDATION; LIPID DIET; LIPID METABOLISM; MALE; MASS SPECTROMETRY; MITOCHONDRIAL RESPIRATION; MOLECULAR PROBE; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PROTEIN ANALYSIS; PROTEOMICS; RESPIRATORY CHAIN; SKELETAL MUSCLE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHROMATOGRAPHY, LIQUID; CITRATE (SI)-SYNTHASE; CITRIC ACID CYCLE; DIET, HIGH-FAT; ELECTRON TRANSPORT COMPLEX IV; LIPID METABOLISM; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MOLECULAR STRUCTURE; MUSCLE, SKELETAL; OBESITY; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; PROTEOME; PROTEOMICS; TIME FACTORS;

MUS;

EID: 84868131974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047996     Document Type: Article

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