-
1
-
-
34249883977
-
Regulation of CD8+ T cell development by thymus-specific proteasomes
-
Murata S., Sasaki K., Kishimoto T., Niwa S., Hayashi H., Takahama Y., Tanaka K. Regulation of CD8+ T cell development by thymus-specific proteasomes. Science 2007, 316:1349-1353.
-
(2007)
Science
, vol.316
, pp. 1349-1353
-
-
Murata, S.1
Sasaki, K.2
Kishimoto, T.3
Niwa, S.4
Hayashi, H.5
Takahama, Y.6
Tanaka, K.7
-
2
-
-
77956035599
-
Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t
-
Florea B.I., Verdoes M., Li N., van der Linden W.A., Geurink P.P., van den Elst H., Hofmann T., de Ru A., van Veelen P.A., Tanaka K., et al. Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t. Chem Biol 2010, 17:795-801.
-
(2010)
Chem Biol
, vol.17
, pp. 795-801
-
-
Florea, B.I.1
Verdoes, M.2
Li, N.3
van der Linden, W.A.4
Geurink, P.P.5
van den Elst, H.6
Hofmann, T.7
de Ru, A.8
van Veelen, P.A.9
Tanaka, K.10
-
3
-
-
65649126339
-
Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery
-
Love K.R., Pandya R.K., Spooner E., Ploegh H.L. Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery. ACS Chem Biol 2009, 4:275-287.
-
(2009)
ACS Chem Biol
, vol.4
, pp. 275-287
-
-
Love, K.R.1
Pandya, R.K.2
Spooner, E.3
Ploegh, H.L.4
-
4
-
-
79955874694
-
Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4
-
Slack J.L., Causey C.P., Luo Y., Thompson P.R. Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4. ACS Chem Biol 2011, 6:466-476.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 466-476
-
-
Slack, J.L.1
Causey, C.P.2
Luo, Y.3
Thompson, P.R.4
-
5
-
-
79955828498
-
Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity
-
Slack J.L., Jones L.E., Bhatia M.M., Thompson P.R. Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity. Biochemistry 2011, 50:3997-4010.
-
(2011)
Biochemistry
, vol.50
, pp. 3997-4010
-
-
Slack, J.L.1
Jones, L.E.2
Bhatia, M.M.3
Thompson, P.R.4
-
6
-
-
80054971718
-
Activity-based protein profiling of protein arginine methyltransferase 1
-
Obianyo O., Causey C.P., Jones J.E., Thompson P.R. Activity-based protein profiling of protein arginine methyltransferase 1. ACS Chem Biol 2011, 6:1127-1135.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 1127-1135
-
-
Obianyo, O.1
Causey, C.P.2
Jones, J.E.3
Thompson, P.R.4
-
7
-
-
78650078496
-
Quantitative reactivity profiling predicts functional cysteines in proteomes
-
Weerapana E., Wang C., Simon G.M., Richter F., Khare S., Dillon M.B.D., Bachovchin D.A., Mowen K., Baker D., Cravatt B.F. Quantitative reactivity profiling predicts functional cysteines in proteomes. Nature 2010, 468:790-795.
-
(2010)
Nature
, vol.468
, pp. 790-795
-
-
Weerapana, E.1
Wang, C.2
Simon, G.M.3
Richter, F.4
Khare, S.5
Dillon, M.B.D.6
Bachovchin, D.A.7
Mowen, K.8
Baker, D.9
Cravatt, B.F.10
-
8
-
-
79959376326
-
Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors
-
Adibekian A., Martin B.R., Wang C., Hsu K.L., Bachovchin D.A., Niessen S., Hoover H., Cravatt B.F. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol 2011, 7:469-478.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 469-478
-
-
Adibekian, A.1
Martin, B.R.2
Wang, C.3
Hsu, K.L.4
Bachovchin, D.A.5
Niessen, S.6
Hoover, H.7
Cravatt, B.F.8
-
9
-
-
34548666006
-
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
-
Blum G., von Degenfeld G., Merchant M.J., Blau H.M., Bogyo M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol 2007, 3:668-677.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 668-677
-
-
Blum, G.1
von Degenfeld, G.2
Merchant, M.J.3
Blau, H.M.4
Bogyo, M.5
-
10
-
-
60749121561
-
Receptor-mediated targeting of cathepsins in professional antigen presenting cells
-
Hillaert U., Verdoes M., Florea B.I., Saragliadis A., Habets K.L., Kuiper J., Van Calenbergh S., Ossendorp F., van der Marel G.A., Driessen C., Overkleeft H.S. Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angew Chem Int Ed 2009, 48:1629-1632.
-
(2009)
Angew Chem Int Ed
, vol.48
, pp. 1629-1632
-
-
Hillaert, U.1
Verdoes, M.2
Florea, B.I.3
Saragliadis, A.4
Habets, K.L.5
Kuiper, J.6
Van Calenbergh, S.7
Ossendorp, F.8
van der Marel, G.A.9
Driessen, C.10
Overkleeft, H.S.11
-
11
-
-
68349148319
-
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes
-
Edgington L.E., Berger A.B., Blum G., Albrow V.E., Paulick M.G., Lineberry N., Bogyo M. Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes. Nat Med 2009, 15:967-973.
-
(2009)
Nat Med
, vol.15
, pp. 967-973
-
-
Edgington, L.E.1
Berger, A.B.2
Blum, G.3
Albrow, V.E.4
Paulick, M.G.5
Lineberry, N.6
Bogyo, M.7
-
12
-
-
77449100648
-
Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain
-
Lee J., Bogyo M. Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. ACS Chem Biol 2010, 5:233-243.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 233-243
-
-
Lee, J.1
Bogyo, M.2
-
13
-
-
79961138638
-
Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently quenched activity-based probes (qABPs)
-
Hu M., Li L., Wu H., Su Y., Yang P.Y., Uttamchandani M., Xu Q.H., Yao S.Q. Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently quenched activity-based probes (qABPs). J Am Chem Soc 2011, 133:12009-12020.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 12009-12020
-
-
Hu, M.1
Li, L.2
Wu, H.3
Su, Y.4
Yang, P.Y.5
Uttamchandani, M.6
Xu, Q.H.7
Yao, S.Q.8
-
14
-
-
79954906546
-
Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division
-
Chang J.T., Ciocca M.L., Kinjyo I., Palanivel V.R., McClurkin C.E., Dejong C.S., Mooney E.C., Kim J.S., Steinel N.C., Oliaro J., et al. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity 2011, 34:492-504.
-
(2011)
Immunity
, vol.34
, pp. 492-504
-
-
Chang, J.T.1
Ciocca, M.L.2
Kinjyo, I.3
Palanivel, V.R.4
McClurkin, C.E.5
Dejong, C.S.6
Mooney, E.C.7
Kim, J.S.8
Steinel, N.C.9
Oliaro, J.10
-
15
-
-
74949101629
-
Activity-based proteome profiling of potential cellular targets of orlistat-an FDA-approved drug with anti-tumor activities
-
Yang P.Y., Liu K., Ngai M.H., Lear M.J., Wenk M.R., Yao S.Q. Activity-based proteome profiling of potential cellular targets of orlistat-an FDA-approved drug with anti-tumor activities. J Am Chem Soc 2010, 132:656-666.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 656-666
-
-
Yang, P.Y.1
Liu, K.2
Ngai, M.H.3
Lear, M.J.4
Wenk, M.R.5
Yao, S.Q.6
-
16
-
-
77952571663
-
Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria
-
Bottcher T., Sieber S.A. Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria. J Am Chem Soc 2010, 132:6964-6972.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 6964-6972
-
-
Bottcher, T.1
Sieber, S.A.2
-
17
-
-
79961161118
-
Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells
-
Eirich J., Orth R., Sieber S.A. Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells. J Am Chem Soc 2011, 133:12144-12153.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 12144-12153
-
-
Eirich, J.1
Orth, R.2
Sieber, S.A.3
-
18
-
-
70149092317
-
Beta-lactam probes as selective chemical-proteomic tools for the identification and functional characterization of resistance associated enzymes in MRSA
-
Staub I., Sieber S.A. Beta-lactam probes as selective chemical-proteomic tools for the identification and functional characterization of resistance associated enzymes in MRSA. J Am Chem Soc 2009, 131:6271-6276.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 6271-6276
-
-
Staub, I.1
Sieber, S.A.2
-
19
-
-
64349085775
-
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes
-
Bachovchin D.A., Brown S.J., Rosen H., Cravatt B.F. Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes. Nat Biotechnol 2009, 27:387-394.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 387-394
-
-
Bachovchin, D.A.1
Brown, S.J.2
Rosen, H.3
Cravatt, B.F.4
-
20
-
-
79959493188
-
In situ kinase profiling reveals functionally relevant properties of native kinases
-
Patricelli M.P., Nomanbhoy T.K., Wu J.Y., Brown H., Zhou D., Zhang J.M., Jagannathan S., Aban A., Okerberg E., Herring C., et al. In situ kinase profiling reveals functionally relevant properties of native kinases. Chem Biol 2011, 18:699-710.
-
(2011)
Chem Biol
, vol.18
, pp. 699-710
-
-
Patricelli, M.P.1
Nomanbhoy, T.K.2
Wu, J.Y.3
Brown, H.4
Zhou, D.5
Zhang, J.M.6
Jagannathan, S.7
Aban, A.8
Okerberg, E.9
Herring, C.10
-
21
-
-
33846248354
-
Functional interrogation of the kinome using nucleotide acyl phosphates
-
Patricelli M.P., Szardenings A.K., Liyanage M., Nomanbhoy T.K., Wu M., Weissig H., Aban A., Chun D., Tanner S., Kozarich J.W. Functional interrogation of the kinome using nucleotide acyl phosphates. Biochemistry 2007, 46:350-358.
-
(2007)
Biochemistry
, vol.46
, pp. 350-358
-
-
Patricelli, M.P.1
Szardenings, A.K.2
Liyanage, M.3
Nomanbhoy, T.K.4
Wu, M.5
Weissig, H.6
Aban, A.7
Chun, D.8
Tanner, S.9
Kozarich, J.W.10
-
22
-
-
76249107767
-
Small molecule probes that target Abl kinase
-
Kalesh K.A., Sim D.S., Wang J., Liu K., Lin Q., Yao S.Q. Small molecule probes that target Abl kinase. Chem Commun 2010, 46:1118-1120.
-
(2010)
Chem Commun
, vol.46
, pp. 1118-1120
-
-
Kalesh, K.A.1
Sim, D.S.2
Wang, J.3
Liu, K.4
Lin, Q.5
Yao, S.Q.6
-
23
-
-
73149109062
-
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
-
Nomura D.K., Long J.Z., Niessen S., Hoover H.S., Ng S.W., Cravatt B.F. Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell 2010, 140:49-61.
-
(2010)
Cell
, vol.140
, pp. 49-61
-
-
Nomura, D.K.1
Long, J.Z.2
Niessen, S.3
Hoover, H.S.4
Ng, S.W.5
Cravatt, B.F.6
-
24
-
-
67349212864
-
Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells
-
Ruckrich T., Kraus M., Gogel J., Beck A., Ovaa H., Verdoes M., Overkleeft H.S., Kalbacher H., Driessen C. Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells. Leukemia 2009, 23:1098-1105.
-
(2009)
Leukemia
, vol.23
, pp. 1098-1105
-
-
Ruckrich, T.1
Kraus, M.2
Gogel, J.3
Beck, A.4
Ovaa, H.5
Verdoes, M.6
Overkleeft, H.S.7
Kalbacher, H.8
Driessen, C.9
-
25
-
-
39349098031
-
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum
-
Arastu-Kapur S., Ponder E.L., Fonovic U.P., Yeoh S., Yuan F., Fonovic M., Grainger M., Phillips C.I., Powers J.C., Bogyo M. Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum. Nat Chem Biol 2008, 4:203-213.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 203-213
-
-
Arastu-Kapur, S.1
Ponder, E.L.2
Fonovic, U.P.3
Yeoh, S.4
Yuan, F.5
Fonovic, M.6
Grainger, M.7
Phillips, C.I.8
Powers, J.C.9
Bogyo, M.10
-
26
-
-
79960566893
-
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion
-
Hall C.I., Reese M.L., Weerapana E., Child M.A., Bowyer P.W., Albrow V.E., Haraldsen J.D., Phillips M.R., Sandoval E.D., Ward G.E., et al. Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. Proc Natl Acad Sci USA 2011, 108:10568-10573.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 10568-10573
-
-
Hall, C.I.1
Reese, M.L.2
Weerapana, E.3
Child, M.A.4
Bowyer, P.W.5
Albrow, V.E.6
Haraldsen, J.D.7
Phillips, M.R.8
Sandoval, E.D.9
Ward, G.E.10
-
27
-
-
80052154599
-
Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
-
Harbut M.B., Velmourougane G., Dalal S., Reiss G., Whisstock J.C., Onder O., Brisson D., McGowan S., Klemba M., Greenbaum D.C. Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases. Proc Natl Acad Sci USA 2011, 108:E526-E534.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
-
-
Harbut, M.B.1
Velmourougane, G.2
Dalal, S.3
Reiss, G.4
Whisstock, J.C.5
Onder, O.6
Brisson, D.7
McGowan, S.8
Klemba, M.9
Greenbaum, D.C.10
-
28
-
-
71449096345
-
Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics
-
Horn M., Nussbaumerova M., Sanda M., Kovarova Z., Srba J., Franta Z., Sojka D., Bogyo M., Caffrey C.R., Kopacek P., Mares M. Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics. Chem Biol 2009, 16:1053-1063.
-
(2009)
Chem Biol
, vol.16
, pp. 1053-1063
-
-
Horn, M.1
Nussbaumerova, M.2
Sanda, M.3
Kovarova, Z.4
Srba, J.5
Franta, Z.6
Sojka, D.7
Bogyo, M.8
Caffrey, C.R.9
Kopacek, P.10
Mares, M.11
-
29
-
-
77955495228
-
Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication
-
Blais D.R., Lyn R.K., Joyce M.A., Rouleau Y., Steenbergen R., Barsby N., Zhu L.F., Pegoraro A.F., Stolow A., Tyrrell D.L., Pezacki J.P. Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication. J Biol Chem 2010, 285:25602-25612.
-
(2010)
J Biol Chem
, vol.285
, pp. 25602-25612
-
-
Blais, D.R.1
Lyn, R.K.2
Joyce, M.A.3
Rouleau, Y.4
Steenbergen, R.5
Barsby, N.6
Zhu, L.F.7
Pegoraro, A.F.8
Stolow, A.9
Tyrrell, D.L.10
Pezacki, J.P.11
-
30
-
-
78649302683
-
Ultrasensitive in situ visualization of active glucocerebrosidase molecules
-
Witte M.D., Kallemeijn W.W., Aten J., Li K.Y., Strijland A., Donker-Koopman W.E., van den Nieuwendijk A.M., Bleijlevens B., Kramer G., Florea B.I., et al. Ultrasensitive in situ visualization of active glucocerebrosidase molecules. Nat Chem Biol 2010, 6:907-913.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 907-913
-
-
Witte, M.D.1
Kallemeijn, W.W.2
Aten, J.3
Li, K.Y.4
Strijland, A.5
Donker-Koopman, W.E.6
van den Nieuwendijk, A.M.7
Bleijlevens, B.8
Kramer, G.9
Florea, B.I.10
-
31
-
-
67449102606
-
Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana
-
Kaschani F., Gu C., Niessen S., Hoover H., Cravatt B.F., van der Hoorn R.A. Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana. Mol Cell Proteomics 2009, 8:1082-1093.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 1082-1093
-
-
Kaschani, F.1
Gu, C.2
Niessen, S.3
Hoover, H.4
Cravatt, B.F.5
van der Hoorn, R.A.6
-
32
-
-
49949106029
-
Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana
-
Wang Z., Gu C., Colby T., Shindo T., Balamurugan R., Waldmann H., Kaiser M., van der Hoorn R.A. Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana. Nat Chem Biol 2008, 4:557-563.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 557-563
-
-
Wang, Z.1
Gu, C.2
Colby, T.3
Shindo, T.4
Balamurugan, R.5
Waldmann, H.6
Kaiser, M.7
van der Hoorn, R.A.8
|