Disease-Associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder

PLoS Computational Biology

Volumn 8, Issue 10, 2012, Pages

  Vacic, Vladimir ^a   Markwick, Phineus R L ^b,c   Oldfield, Christopher J ^d   Zhao, Xiaoyue ^e,j   Haynes, Chad ^f,k   Uversky, Vladimir N ^g,h   Iakoucheva, Lilia M ⁱ  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^f ROCKEFELLER UNIVERSITY   (United States)

^g UNIVERSITY OF SOUTH FLORIDA   (United States)

^h INSTITUTE FOR BIOLOGICAL INSTRUMENTATION   (Russian Federation)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j GOOGLE INC   (United States)

^k WaterSmart Software   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE CONTROL; ORDER DISORDER TRANSITIONS; PROTEINS;

AMINO ACID SUBSTITUTION; CONSERVED PROTEINS; EVOLUTIONARY CONSERVATIONS; FOLDED PROTEINS; HUMAN PROTEOME; INTRINSICALLY DISORDERED PROTEINS; INTRINSICALLY DISORDERED REGIONS; ORDERING TRANSITIONS; PROTEIN FUNCTIONS; PROTEINS STRUCTURES;

MOLECULAR DYNAMICS;

EID: 84868115657     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002709     Document Type: Article

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