Loss of protein structure stability as a major causative factor in monogenic disease

Journal of Molecular Biology

Volumn 353, Issue 2, 2005, Pages 459-473

  Yue, Peng ^a,b   Li, Zhaolong ^a   Moult, John ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Mis sense mutations; Monogenic disease; Protein stability; Protein structure; Single nucleotide polymorphisms

Indexed keywords

ARTICLE; GENE MUTATION; GENE VECTOR; GENETIC DISORDER; GENETIC VARIABILITY; HYDROPHOBICITY; MISSENSE MUTATION; MOLECULAR INTERACTION; MONOGENIC DISEASE; MUTAGENESIS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 25144523127     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.08.020     Document Type: Article

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