메뉴 건너뛰기




Volumn 4, Issue 10, 2012, Pages 2197-2217

Hepatitis C virus and natural compounds: A new antiviral approach?

Author keywords

Direct acting antivirals; Flavonoids; Hepatitis C virus; Natural molecules

Indexed keywords

3 HYDROXY CARUILIGNAN C; ANTIVIRUS AGENT; APIGENIN; BIOFLAVONOID; CORILAGIN; CYCLOSPORIN A; EPIGALLOCATECHIN GALLATE; FLAVONOID; HEPATITIS C VACCINE; HONOKIOL; INTERFERON; LADANEIN; LUTEOLIN; NARINGENIN; NATURAL PRODUCT; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 5B; PEGINTERFERON ALPHA; PEGINTERFERON ALPHA PLUS RIBAVIRIN; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROTEINASE INHIBITOR; QUERCETIN; RIBAVIRIN; SILIBININ; SILYBUM MARIANUM EXTRACT; SILYMARIN; TELAPREVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84868095935     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v4102197     Document Type: Review
Times cited : (121)

References (110)
  • 1
    • 0034489957 scopus 로고    scopus 로고
    • Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine
    • Lee, K.H. Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine. Public Health Nutr. 2000, 3, 515-522.
    • (2000) Public Health Nutr , vol.3 , pp. 515-522
    • Lee, K.H.1
  • 2
    • 27844474247 scopus 로고    scopus 로고
    • Drug discovery from medicinal plants
    • Balunas, M.J.; Kinghorn, A.D. Drug discovery from medicinal plants. Life Sci. 2005, 78, 431-441.
    • (2005) Life Sci , vol.78 , pp. 431-441
    • Balunas, M.J.1    Kinghorn, A.D.2
  • 3
    • 0034082239 scopus 로고    scopus 로고
    • The influence of natural products upon drug discovery
    • Newman, D.J.; Cragg, G.M.; Snader, K.M. The influence of natural products upon drug discovery. Nat. Prod. Rep. 2000, 17, 215-234.
    • (2000) Nat. Prod. Rep , vol.17 , pp. 215-234
    • Newman, D.J.1    Cragg, G.M.2    Snader, K.M.3
  • 4
    • 84858308226 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the 30 years from 1981 to 2010
    • Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 2012, 75, 311-335.
    • (2012) J. Nat. Prod , vol.75 , pp. 311-335
    • Newman, D.J.1    Cragg, G.M.2
  • 5
    • 84973140910 scopus 로고    scopus 로고
    • Natural Products in Drug Discovery: Impacts and Opportunities-An Assessment
    • In, Brahmachari, G., Ed.; World Scientific Publishing Company: Singapore
    • Brahmachari, G. Natural Products in Drug Discovery: Impacts and Opportunities-An Assessment. In Bioactive Natural Products; Brahmachari, G., Ed.; World Scientific Publishing Company: Singapore, 2011; pp. 1-199.
    • (2011) Bioactive Natural Products , pp. 1-199
    • Brahmachari, G.1
  • 6
    • 77957141554 scopus 로고    scopus 로고
    • Ethnobotanical Research and Traditional Health Care in Developing Countries
    • In, Bodeker, G., Bhat, K.K.S., Burley, J., Vantomme, P., Eds.; Food and Agriculture Organization of the United Nations: Rome, Italy
    • Balick, M.J.; Cox, P.A. Ethnobotanical Research and Traditional Health Care in Developing Countries. In Medicinal Plants for Forest Conservation and Health Care; Bodeker, G., Bhat, K.K.S., Burley, J., Vantomme, P., Eds.; Food and Agriculture Organization of the United Nations: Rome, Italy, 1997; pp. 12-23.
    • (1997) Medicinal Plants for Forest Conservation and Health Care , pp. 12-23
    • Balick, M.J.1    Cox, P.A.2
  • 8
    • 0023201072 scopus 로고
    • In vitro antiviral activity of a saponin from Anagallis arvensis, Primulaceae, against herpes simplex virus and poliovirus
    • Amoros, M.; Fauconnier, B.; Girre, R. L. In vitro antiviral activity of a saponin from Anagallis arvensis, Primulaceae, against herpes simplex virus and poliovirus. Antivir. Res. 1987, 8, 13-25.
    • (1987) Antivir. Res , vol.8 , pp. 13-25
    • Amoros, M.1    Fauconnier, B.2    Girre, R.L.3
  • 9
    • 0028956115 scopus 로고
    • Antiherpetic in vitro activity of Gamochaeta simplicicaulis extract
    • Cavallaro, L.; Garcia, G.; Broussalis, A. Antiherpetic in vitro activity of Gamochaeta simplicicaulis extract. Phytother. Res. 1995, 9, 176-179.
    • (1995) Phytother. Res , vol.9 , pp. 176-179
    • Cavallaro, L.1    Garcia, G.2    Broussalis, A.3
  • 10
    • 0023912917 scopus 로고
    • Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese medicinal herbs
    • Chang, R.S.; Yeung, H.W. Inhibition of growth of human immunodeficiency virus in vitro by crude extracts of Chinese medicinal herbs. Antivir. Res. 1988, 9, 163-175.
    • (1988) Antivir. Res , vol.9 , pp. 163-175
    • Chang, R.S.1    Yeung, H.W.2
  • 11
    • 0024314925 scopus 로고
    • Isolation, purification, and partial characterization of prunellin, an anti-HIV component from aqueous extracts of Prunella vulgaris
    • Tabba, H.D.; Chang, R.S.; Smith, K.M. Isolation, purification, and partial characterization of prunellin, an anti-HIV component from aqueous extracts of Prunella vulgaris. Antivir. Res. 1989, 11, 263-273.
    • (1989) Antivir. Res , vol.11 , pp. 263-273
    • Tabba, H.D.1    Chang, R.S.2    Smith, K.M.3
  • 12
    • 0026528296 scopus 로고
    • Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris
    • Yao, X.J.; Wainberg, M.A.; Parniak, M.A. Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris. Virology 1992, 187, 56-62.
    • (1992) Virology , vol.187 , pp. 56-62
    • Yao, X.J.1    Wainberg, M.A.2    Parniak, M.A.3
  • 13
    • 79956329892 scopus 로고    scopus 로고
    • Viral infectious disease and natural products with antiviral activity
    • Kitazato, K.; Wang, Y.; Kobayashi, N. Viral infectious disease and natural products with antiviral activity. Drug Discov. Ther. 2007, 1, 14-22.
    • (2007) Drug Discov. Ther , vol.1 , pp. 14-22
    • Kitazato, K.1    Wang, Y.2    Kobayashi, N.3
  • 14
    • 0024439136 scopus 로고
    • Plant photosensitizers with antiviral properties
    • Hudson, J.B. Plant photosensitizers with antiviral properties. Antivir. Res. 1989, 12, 55-74.
    • (1989) Antivir. Res , vol.12 , pp. 55-74
    • Hudson, J.B.1
  • 16
    • 34547769225 scopus 로고    scopus 로고
    • Inhibition of HCV RNA-dependent RNA polymerase activity by aqueous extract from Fructus Ligustri Lucidi
    • Kong, L.; Li, S.; Han, X.; Xiang, Z.; Fang, X.; Li, B.; Wang, W.; Zhong, H.; Gao, J.; Ye, L. Inhibition of HCV RNA-dependent RNA polymerase activity by aqueous extract from Fructus Ligustri Lucidi. Virus Res. 2007, 128, 9-17.
    • (2007) Virus Res , vol.128 , pp. 9-17
    • Kong, L.1    Li, S.2    Han, X.3    Xiang, Z.4    Fang, X.5    Li, B.6    Wang, W.7    Zhong, H.8    Gao, J.9    Ye, L.10
  • 17
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo, Q.L.; Kuo, G.; Weiner, A.J.; Overby, L.R.; Bradley, D.W.; Houghton, M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989, 244, 359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 18
    • 78751621217 scopus 로고    scopus 로고
    • Evolving epidemiology of hepatitis C virus
    • Lavanchy, D. Evolving epidemiology of hepatitis C virus. Clin. Microbiol. Infect. 2011, 17, 107-115.
    • (2011) Clin. Microbiol. Infect , vol.17 , pp. 107-115
    • Lavanchy, D.1
  • 21
    • 79955669252 scopus 로고    scopus 로고
    • A new standard of care for the treatment of chronic HCV infection
    • Hofmann, W.P.; Zeuzem, S. A new standard of care for the treatment of chronic HCV infection. Nat. Rev. Gastroenterol. Hepatol. 2011, 8, 257-264.
    • (2011) Nat. Rev. Gastroenterol. Hepatol , vol.8 , pp. 257-264
    • Hofmann, W.P.1    Zeuzem, S.2
  • 22
    • 84862161013 scopus 로고    scopus 로고
    • Treating hepatitis C: Current standard of care and emerging direct-acting antiviral agents
    • Poordad, F.; Dieterich, D. Treating hepatitis C: Current standard of care and emerging direct-acting antiviral agents. J. Viral Hepat. 2012, 19, 449-464.
    • (2012) J. Viral Hepat , vol.19 , pp. 449-464
    • Poordad, F.1    Dieterich, D.2
  • 25
    • 0035003885 scopus 로고    scopus 로고
    • Down-regulation of translation driven by hepatitis C virus internal ribosomal entry site by the 3' untranslated region of RNA
    • Murakami, K.; Abe, M.; Kageyama, T.; Kamoshita, N.; Nomoto, A. Down-regulation of translation driven by hepatitis C virus internal ribosomal entry site by the 3' untranslated region of RNA. Arch. Virol. 2001, 146, 729-741.
    • (2001) Arch. Virol , vol.146 , pp. 729-741
    • Murakami, K.1    Abe, M.2    Kageyama, T.3    Kamoshita, N.4    Nomoto, A.5
  • 26
    • 0034747214 scopus 로고    scopus 로고
    • Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication
    • Friebe, P.; Lohmann, V.; Krieger, N.; Bartenschlager, R. Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication. J. Virol. 2001, 75, 12047-12057.
    • (2001) J. Virol , vol.75 , pp. 12047-12057
    • Friebe, P.1    Lohmann, V.2    Krieger, N.3    Bartenschlager, R.4
  • 27
    • 0037332361 scopus 로고    scopus 로고
    • 3' nontranslated RNA signals required for replication of hepatitis C virus RNA
    • Yi, M.K.; Lemon, S.M. 3' nontranslated RNA signals required for replication of hepatitis C virus RNA. J. Virol. 2003, 77, 3557-3568.
    • (2003) J. Virol , vol.77 , pp. 3557-3568
    • Yi, M.K.1    Lemon, S.M.2
  • 33
    • 0344443242 scopus 로고    scopus 로고
    • Replication of the hepatitis C virus in cell culture
    • Bartenschlager, R.; Kaul, A.; Sparacio, S. Replication of the hepatitis C virus in cell culture. Antivir. Res. 2003, 60, 91-102.
    • (2003) Antivir. Res , vol.60 , pp. 91-102
    • Bartenschlager, R.1    Kaul, A.2    Sparacio, S.3
  • 34
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • Bartosch, B.; Dubuisson, J.; Cosset, F.L. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J. Exp. Med. 2003, 197, 633-642.
    • (2003) J. Exp. Med , vol.197 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 35
    • 0038508803 scopus 로고    scopus 로고
    • Cell surface expression of functional hepatitis C virus E1 and E2 glycoproteins
    • Drummer, H.E.; Maerz, A.; Poumbourios, P. Cell surface expression of functional hepatitis C virus E1 and E2 glycoproteins. FEBS Lett. 2003, 546, 385-390.
    • (2003) FEBS Lett , vol.546 , pp. 385-390
    • Drummer, H.E.1    Maerz, A.2    Poumbourios, P.3
  • 42
    • 60149090028 scopus 로고    scopus 로고
    • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
    • Ploss, A.; Evans, M.J.; Gaysinskaya, V.A.; Panis, M.; You, H.; de Jong, Y.P.; Rice, C.M. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature 2009, 457, 882-886.
    • (2009) Nature , vol.457 , pp. 882-886
    • Ploss, A.1    Evans, M.J.2    Gaysinskaya, V.A.3    Panis, M.4    You, H.5    de Jong, Y.P.6    Rice, C.M.7
  • 43
    • 59649117842 scopus 로고    scopus 로고
    • Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection
    • Liu, S.; Yang, W.; Shen, L.; Turner, J.R.; Coyne, C.B.; Wang, T. Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection. J. Virol. 2009, 83, 2011-2014.
    • (2009) J. Virol , vol.83 , pp. 2011-2014
    • Liu, S.1    Yang, W.2    Shen, L.3    Turner, J.R.4    Coyne, C.B.5    Wang, T.6
  • 47
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger, D.; Wolk, B.; Gosert, R.; Bianchi, L.; Blum, H.E.; Moradpour, D.; Bienz, K. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 2002, 76, 5974-5984.
    • (2002) J. Virol , vol.76 , pp. 5974-5984
    • Egger, D.1    Wolk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 48
    • 0344012048 scopus 로고    scopus 로고
    • Membrane association of hepatitis C virus nonstructural proteins and identification of the membrane alteration that harbors the viral replication complex
    • Moradpour, D.; Gosert, R.; Egger, D.; Penin, F.; Blum, H.E.; Bienz, K. Membrane association of hepatitis C virus nonstructural proteins and identification of the membrane alteration that harbors the viral replication complex. Antivir. Res. 2003, 60, 103-109.
    • (2003) Antivir. Res , vol.60 , pp. 103-109
    • Moradpour, D.1    Gosert, R.2    Egger, D.3    Penin, F.4    Blum, H.E.5    Bienz, K.6
  • 50
    • 84861217162 scopus 로고    scopus 로고
    • Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity
    • Bianco, A.; Reghellin, V.; Donnici, L.; Fenu, S.; Alvarez, R. Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity. PLoS Pathog. 2012, 8, e1002576.
    • (2012) PLoS Pathog , vol.8
    • Bianco, A.1    Reghellin, V.2    Donnici, L.3    Fenu, S.4    Alvarez, R.5
  • 54
    • 78651252353 scopus 로고    scopus 로고
    • Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly
    • Jirasko, V.; Montserret, R.; Lee, J.Y.; Gouttenoire, J.; Moradpour, D.; Penin, F.; Bartenschlager, R. Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. PLoS Pathog. 2010, 6, e1001233.
    • (2010) PLoS Pathog , vol.6
    • Jirasko, V.1    Montserret, R.2    Lee, J.Y.3    Gouttenoire, J.4    Moradpour, D.5    Penin, F.6    Bartenschlager, R.7
  • 55
    • 78650062692 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins
    • Ma, Y.; Anantpadma, M.; Timpe, J.M.; Shanmugam, S.; Singh, S.M.; Lemon, S.M.; Yi, M. Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. J. Virol. 2011, 85, 86-97.
    • (2011) J. Virol , vol.85 , pp. 86-97
    • Ma, Y.1    Anantpadma, M.2    Timpe, J.M.3    Shanmugam, S.4    Singh, S.M.5    Lemon, S.M.6    Yi, M.7
  • 56
    • 78951472458 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes
    • Stapleford, K.A.; Lindenbach, B.D. Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes. J. Virol. 2011, 85, 1706-1717.
    • (2011) J. Virol , vol.85 , pp. 1706-1717
    • Stapleford, K.A.1    Lindenbach, B.D.2
  • 57
    • 79960951066 scopus 로고    scopus 로고
    • A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly
    • Boson, B.; Granio, O.; Bartenschlager, R.; Cosset, F.L. A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly. PLoS Pathog. 2011, 7, e1002144.
    • (2011) PLoS Pathog , vol.7
    • Boson, B.1    Granio, O.2    Bartenschlager, R.3    Cosset, F.L.4
  • 59
    • 34250337631 scopus 로고    scopus 로고
    • Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
    • Huang, H.; Sun, F.; Owen, D.M.; Li, W.; Chen, Y.; Gale, M.; Ye, J. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc. Natl. Acad. Sci. USA 2007, 104, 5848-5853.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5848-5853
    • Huang, H.1    Sun, F.2    Owen, D.M.3    Li, W.4    Chen, Y.5    Gale, M.6    Ye, J.7
  • 60
    • 39749098739 scopus 로고    scopus 로고
    • Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
    • Gastaminza, P.; Cheng, G.; Wieland, S.; Zhong, J.; Liao, W.; Chisari, F.V. Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion. J. Virol. 2008, 82, 2120-2129.
    • (2008) J. Virol , vol.82 , pp. 2120-2129
    • Gastaminza, P.1    Cheng, G.2    Wieland, S.3    Zhong, J.4    Liao, W.5    Chisari, F.V.6
  • 61
    • 34247583381 scopus 로고    scopus 로고
    • Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin
    • Polyak, S.J.; Morishima, C.; Shuhart, M.C.; Wang, C.C.; Liu, Y.; Lee, D.Y. Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin. Gastroenterology 2007, 132, 1925-1936.
    • (2007) Gastroenterology , vol.132 , pp. 1925-1936
    • Polyak, S.J.1    Morishima, C.2    Shuhart, M.C.3    Wang, C.C.4    Liu, Y.5    Lee, D.Y.6
  • 63
  • 66
    • 79953238831 scopus 로고    scopus 로고
    • Inhibition of HCV 3a core gene through Silymarin and its fractions
    • Ashfaq, U.A.; Javed, T.; Rehman, S.; Nawaz, Z.; Riazuddin, S. Inhibition of HCV 3a core gene through Silymarin and its fractions. Virol. J. 2011, 8, 153.
    • (2011) Virol. J , vol.8 , pp. 153
    • Ashfaq, U.A.1    Javed, T.2    Rehman, S.3    Nawaz, Z.4    Riazuddin, S.5
  • 69
    • 77952426576 scopus 로고    scopus 로고
    • Successful prevention of hepatitis C virus (HCV) liver graft reinfection by silibinin mono-therapy
    • Neumann, U.P.; Biermer, M.; Eurich, D.; Neuhaus, P.; Berg, T. Successful prevention of hepatitis C virus (HCV) liver graft reinfection by silibinin mono-therapy. J. Hepatol. 2010, 52, 951-952.
    • (2010) J. Hepatol , vol.52 , pp. 951-952
    • Neumann, U.P.1    Biermer, M.2    Eurich, D.3    Neuhaus, P.4    Berg, T.5
  • 70
    • 79951683184 scopus 로고    scopus 로고
    • Silibinin monotherapy prevents graft infection after orthotopic liver transplantation in a patient with chronic hepatitis C
    • Beinhardt, S.; Rasoul-Rockenschaub, S.; Scherzer, T.M.; Ferenci, P. Silibinin monotherapy prevents graft infection after orthotopic liver transplantation in a patient with chronic hepatitis C. J. Hepatol. 2011, 54, 591-592.
    • (2011) J. Hepatol , vol.54 , pp. 591-592
    • Beinhardt, S.1    Rasoul-Rockenschaub, S.2    Scherzer, T.M.3    Ferenci, P.4
  • 74
    • 84863099257 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate inhibits the replication cycle of hepatitis C virus
    • Chen, C.; Qiu, H.; Gong, J.; Liu, Q.; Xiao, H.; Chen, X.-W.; Sun, B.-L.; Yang, R.-G. (-)-Epigallocatechin-3-gallate inhibits the replication cycle of hepatitis C virus. Arch. Virol. 2012, 157, 1301-1312.
    • (2012) Arch. Virol , vol.157 , pp. 1301-1312
    • Chen, C.1    Qiu, H.2    Gong, J.3    Liu, Q.4    Xiao, H.5    Chen, X.-W.6    Sun, B.-L.7    Yang, R.-G.8
  • 76
    • 43949087893 scopus 로고    scopus 로고
    • Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin
    • Nahmias, Y.; Goldwasser, J.; Casali, M.; van Poll, D.; Wakita, T.; Chung, R.T.; Yarmush, M.L. Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology 2008, 47, 1437-1445.
    • (2008) Hepatology , vol.47 , pp. 1437-1445
    • Nahmias, Y.1    Goldwasser, J.2    Casali, M.3    van Poll, D.4    Wakita, T.5    Chung, R.T.6    Yarmush, M.L.7
  • 77
    • 80054728029 scopus 로고    scopus 로고
    • Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism
    • Goldwasser, J.; Cohen, P.Y.; Lin, W.; Kitsberg, D.; Balaguer, P.; Polyak, S.J.; Chung, R.T.; Yarmush, M.L.; Nahmias, Y. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. J. Hepatol. 2011, 55, 963-971.
    • (2011) J. Hepatol , vol.55 , pp. 963-971
    • Goldwasser, J.1    Cohen, P.Y.2    Lin, W.3    Kitsberg, D.4    Balaguer, P.5    Polyak, S.J.6    Chung, R.T.7    Yarmush, M.L.8    Nahmias, Y.9
  • 82
    • 84859847811 scopus 로고    scopus 로고
    • Anti-hepatitis C virus activity of 3-hydroxy caruilignan C from Swietenia macrophylla stems
    • Wu, S.F.; Lin, C.K.; Chuang, Y.S.; Chang, F.R.; Tseng, C.K.; Wu, Y.C.; Lee, J.C. Anti-hepatitis C virus activity of 3-hydroxy caruilignan C from Swietenia macrophylla stems. J. Viral Hepatitis 2012, 19, 364-370.
    • (2012) J. Viral Hepatitis , vol.19 , pp. 364-370
    • Wu, S.F.1    Lin, C.K.2    Chuang, Y.S.3    Chang, F.R.4    Tseng, C.K.5    Wu, Y.C.6    Lee, J.C.7
  • 83
    • 84855675976 scopus 로고    scopus 로고
    • Inhibitory effects of polyphenols toward HCV from the mangrove plant Excoecaria agallocha L
    • Li, Y.; Yu, S.; Liu, D.; Proksch, P.; Lin, W. Inhibitory effects of polyphenols toward HCV from the mangrove plant Excoecaria agallocha L. Bioorg. Med. Chem. Lett. 2012, 22, 1099-1102.
    • (2012) Bioorg. Med. Chem. Lett , vol.22 , pp. 1099-1102
    • Li, Y.1    Yu, S.2    Liu, D.3    Proksch, P.4    Lin, W.5
  • 86
    • 33645307385 scopus 로고    scopus 로고
    • Effects of Silybum marianum on serum hepatitis C virus RNA, alanine aminotransferase levels and well-being in patients with chronic hepatitis C
    • Gordon, A.; Hobbs, D.A.; Bowden, D.S.; Bailey, M.J.; Mitchell, J.; Francis, A.J.P.; Roberts, S.K. Effects of Silybum marianum on serum hepatitis C virus RNA, alanine aminotransferase levels and well-being in patients with chronic hepatitis C. J. Gastroenterol. Hepatol. 2006, 21, 275-280.
    • (2006) J. Gastroenterol. Hepatol , vol.21 , pp. 275-280
    • Gordon, A.1    Hobbs, D.A.2    Bowden, D.S.3    Bailey, M.J.4    Mitchell, J.5    Francis, A.J.P.6    Roberts, S.K.7
  • 87
    • 84863905251 scopus 로고    scopus 로고
    • Silymarin in NASH and C Hepatitis (SyNCH) Study Group Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: A randomized controlled trial
    • Fried, M.W.; Navarro, V.J.; Afdhal, N.; Belle, S.H.; Wahed, A.S.; Hawke, R.L.; Doo, E.; Meyers, C.M.; Reddy, K.R. Silymarin in NASH and C Hepatitis (SyNCH) Study Group Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. JAMA 2012, 308, 274-282.
    • (2012) JAMA , vol.308 , pp. 274-282
    • Fried, M.W.1    Navarro, V.J.2    Afdhal, N.3    Belle, S.H.4    Wahed, A.S.5    Hawke, R.L.6    Doo, E.7    Meyers, C.M.8    Reddy, K.R.9
  • 88
    • 37549005182 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract
    • Wen, Z.; Dumas, T.E.; Schrieber, S.J.; Hawke, R.L.; Fried, M.W.; Smith, P.C. Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. Drug Metab. Dispos. 2008, 36, 65-72.
    • (2008) Drug Metab. Dispos , vol.36 , pp. 65-72
    • Wen, Z.1    Dumas, T.E.2    Schrieber, S.J.3    Hawke, R.L.4    Fried, M.W.5    Smith, P.C.6
  • 89
    • 0042334847 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals
    • Chow, H.H.S.; Cai, Y.; Hakim, I.A.; Crowell, J.A.; Shahi, F.; Brooks, C.A.; Dorr, R.T.; Hara, Y.; Alberts, D.S. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin. Cancer Res. 2003, 9, 3312-3319.
    • (2003) Clin. Cancer Res , vol.9 , pp. 3312-3319
    • Chow, H.H.S.1    Cai, Y.2    Hakim, I.A.3    Crowell, J.A.4    Shahi, F.5    Brooks, C.A.6    Dorr, R.T.7    Hara, Y.8    Alberts, D.S.9
  • 90
    • 34547408337 scopus 로고    scopus 로고
    • Activity of compounds from Chinese herbal medicine Rhodiola kirilowii (Regel) Maxim against HCV NS3 serine protease
    • Zuo, G.; Li, Z.; Chen, L.; Xu, X. Activity of compounds from Chinese herbal medicine Rhodiola kirilowii (Regel) Maxim against HCV NS3 serine protease. Antivir. Res. 2007, 76, 86-92.
    • (2007) Antivir. Res , vol.76 , pp. 86-92
    • Zuo, G.1    Li, Z.2    Chen, L.3    Xu, X.4
  • 91
    • 80053568355 scopus 로고    scopus 로고
    • (-)-Epigallocatechin gallate inhibits hepatitis C virus (HCV) viral protein NS5B
    • Roh, C.; Jo, S.-K. (-)-Epigallocatechin gallate inhibits hepatitis C virus (HCV) viral protein NS5B. Talanta 2011, 85, 2639-2642.
    • (2011) Talanta , vol.85 , pp. 2639-2642
    • Roh, C.1    Jo, S.-K.2
  • 93
    • 27644518720 scopus 로고    scopus 로고
    • Antiviral effect of catechins in green tea on influenza virus
    • Song, J.-M.; Lee, K.-H.; Seong, B.-L. Antiviral effect of catechins in green tea on influenza virus. Antivir. Res. 2005, 68, 66-74.
    • (2005) Antivir. Res , vol.68 , pp. 66-74
    • Song, J.-M.1    Lee, K.-H.2    Seong, B.-L.3
  • 94
  • 95
    • 84864925205 scopus 로고    scopus 로고
    • A cell-based, microplate colorimetric screen identifies 7, 8-benzoflavone and green tea gallate catechins as inhibitors of the hepatitis C virus
    • Fukazawa, H.; Suzuki, T.; Wakita, T. A cell-based, microplate colorimetric screen identifies 7, 8-benzoflavone and green tea gallate catechins as inhibitors of the hepatitis C virus. Biol. Pharm. Bull. 2012, 35, 1320-1327.
    • (2012) Biol. Pharm. Bull , vol.35 , pp. 1320-1327
    • Fukazawa, H.1    Suzuki, T.2    Wakita, T.3
  • 96
    • 20044368479 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes
    • Allister, E.M.; Borradaile, N.M.; Edwards, J.Y.; Huff, M.W. Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes. Diabetes 2005, 54, 1676-1683.
    • (2005) Diabetes , vol.54 , pp. 1676-1683
    • Allister, E.M.1    Borradaile, N.M.2    Edwards, J.Y.3    Huff, M.W.4
  • 97
    • 0033962385 scopus 로고    scopus 로고
    • Hypocholesterolemic effects of dietary citrus juices in rabbits
    • Kurowska, E.M.; Borradaile, N.M.; Spence, J.D.; Carroll, K.K. Hypocholesterolemic effects of dietary citrus juices in rabbits. Nutr. Res. 2000, 20, 121-129.
    • (2000) Nutr. Res , vol.20 , pp. 121-129
    • Kurowska, E.M.1    Borradaile, N.M.2    Spence, J.D.3    Carroll, K.K.4
  • 98
    • 0034989204 scopus 로고    scopus 로고
    • Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP
    • Wilcox, L.J.; Borradaile, N.M.; de Dreu, L.E.; Huff, M.W. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J. Lipid Res. 2001, 42, 725-734.
    • (2001) J. Lipid Res , vol.42 , pp. 725-734
    • Wilcox, L.J.1    Borradaile, N.M.2    de Dreu, L.E.3    Huff, M.W.4
  • 99
    • 0033989278 scopus 로고    scopus 로고
    • De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
    • Luo, G.; Hamatake, R.K.; Mathis, D.M.; Racela, J.; Rigat, K.L.; Lemm, J.; Colonno, R.J. De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J. Virol. 2000, 74, 851-863.
    • (2000) J. Virol , vol.74 , pp. 851-863
    • Luo, G.1    Hamatake, R.K.2    Mathis, D.M.3    Racela, J.4    Rigat, K.L.5    Lemm, J.6    Colonno, R.J.7
  • 100
    • 16344385141 scopus 로고    scopus 로고
    • Anti-hepatitis C virus effect of citrus unshiu peel and its active ingredient nobiletin
    • Suzuki, M.; Sasaki, K.; Yoshizaki, F.; Oguchi, K.; Fujisawa, M.; Cyong, J.-C. Anti-hepatitis C virus effect of citrus unshiu peel and its active ingredient nobiletin. Am. J. Chin. Med. 2005, 33, 87-94.
    • (2005) Am. J. Chin. Med , vol.33 , pp. 87-94
    • Suzuki, M.1    Sasaki, K.2    Yoshizaki, F.3    Oguchi, K.4    Fujisawa, M.5    Cyong, J.-C.6
  • 102
    • 28544434766 scopus 로고    scopus 로고
    • In vitro anti-HCV activities of Saxifraga melanocentra and its related polyphenolic compounds
    • Zuo, G.-Y.; Li, Z.-Q.; Chen, L.-R.; Xu, X.-J. In vitro anti-HCV activities of Saxifraga melanocentra and its related polyphenolic compounds. Antivir. Chem. Chemother. 2005, 16, 393-398.
    • (2005) Antivir. Chem. Chemother , vol.16 , pp. 393-398
    • Zuo, G.-Y.1    Li, Z.-Q.2    Chen, L.-R.3    Xu, X.-J.4
  • 103
    • 8844263129 scopus 로고    scopus 로고
    • Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease
    • Duan, D.; Li, Z.; Luo, H.; Zhang, W.; Chen, L.; Xu, X. Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease. Bioorg. Med. Chem. Lett. 2004, 14, 6041-6044.
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , pp. 6041-6044
    • Duan, D.1    Li, Z.2    Luo, H.3    Zhang, W.4    Chen, L.5    Xu, X.6
  • 104
    • 0037345685 scopus 로고    scopus 로고
    • Medicinal herbs for hepatitis C virus infection: A Cochrane hepatobiliary systematic review of randomized trials
    • Liu, J.; Manheimer, E.; Tsutani, K.; Gluud, C. Medicinal herbs for hepatitis C virus infection: A Cochrane hepatobiliary systematic review of randomized trials. Am. J. Gastroenterol. 2003, 98, 538-544.
    • (2003) Am. J. Gastroenterol , vol.98 , pp. 538-544
    • Liu, J.1    Manheimer, E.2    Tsutani, K.3    Gluud, C.4
  • 105
    • 79958119860 scopus 로고    scopus 로고
    • A single arm phase II study of a Far-Eastern traditional herbal formulation (sho-sai-ko-to or xiao-chai-hu-tang) in chronic hepatitis C patients
    • Deng, G.; Kurtz, R.C.; Vickers, A.; Lau, N.; Yeung, K.S.; Shia, J.; Cassileth, B. A single arm phase II study of a Far-Eastern traditional herbal formulation (sho-sai-ko-to or xiao-chai-hu-tang) in chronic hepatitis C patients. J. Ethnopharmacol. 2011, 136, 83-87.
    • (2011) J. Ethnopharmacol , vol.136 , pp. 83-87
    • Deng, G.1    Kurtz, R.C.2    Vickers, A.3    Lau, N.4    Yeung, K.S.5    Shia, J.6    Cassileth, B.7
  • 106
    • 0033758416 scopus 로고    scopus 로고
    • Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease
    • Hussein, G.; Miyashiro, H.; Nakamura, N.; Hattori, M.; Kakiuchi, N.; Shimotohno, K. Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease. Phytother. Res. 2000, 14, 510-516.
    • (2000) Phytother. Res , vol.14 , pp. 510-516
    • Hussein, G.1    Miyashiro, H.2    Nakamura, N.3    Hattori, M.4    Kakiuchi, N.5    Shimotohno, K.6
  • 107
    • 79956326437 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source
    • Ravikumar, Y.S.; Ray, U.; Nandhitha, M.; Perween, A.; Raja Naika, H.; Khanna, N.; Das, S. Inhibition of hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source. Virus Res. 2011, 158, 89-97.
    • (2011) Virus Res , vol.158 , pp. 89-97
    • Ravikumar, Y.S.1    Ray, U.2    Nandhitha, M.3    Perween, A.4    Raja Naika, H.5    Khanna, N.6    Das, S.7
  • 108
    • 79959605633 scopus 로고    scopus 로고
    • San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression
    • Lee, J.C.; Tseng, C.K.; Wu, S.F.; Chang, F.R.; Chiu, C.C.; Wu, Y.C. San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression. J. Viral Hepat. 2011, 18, e315-e324.
    • (2011) J. Viral Hepat , vol.18
    • Lee, J.C.1    Tseng, C.K.2    Wu, S.F.3    Chang, F.R.4    Chiu, C.C.5    Wu, Y.C.6
  • 110
    • 0036289062 scopus 로고    scopus 로고
    • Long-term treatment of chronic hepatitis C with glycyrrhizin [stronger neo-minophagen C (SNMC)] for preventing liver cirrhosis and hepatocellular carcinoma
    • Kumada, H. Long-term treatment of chronic hepatitis C with glycyrrhizin [stronger neo-minophagen C (SNMC)] for preventing liver cirrhosis and hepatocellular carcinoma. Oncology 2002, 62 (Suppl. 1), 94-100.
    • (2002) Oncology , vol.62 , Issue.SUPPL. 1 , pp. 94-100
    • Kumada, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.