Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine

Public Health Nutrition

Volumn 3, Issue 4 A, 2000, Pages 515-522

  Lee, K H ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Chinese medicine; Drug development; Drug discovery; Medicinal herbs

Indexed keywords

ALTERNATIVE MEDICINE; CHINESE MEDICINE; DIET SUPPLEMENTATION; DRUG ACTIVITY; DRUG EFFICACY; DRUG FORMULATION; DRUG INDUCED DISEASE; DRUG MECHANISM; DRUG METABOLISM; DRUG SAFETY; HERB; HERBAL MEDICINE; HUMAN; MEDICAL RESEARCH; MEDICINAL PLANT; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 0034489957     PISSN: 13689800     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1368980000000604     Document Type: Review

References (59)

1. Antineoplastic agents from Chinese traditional medicine and their analogs
2. Scientific Chinese herbal medicine: Research and movements toward worldwide acceptance
3. Recent new drugs discovered and developed from Chinese medicine
4. Antitumor agents 195. Anticancer drug design based on plant-derived natural products
5. Antitumor agents 188. Highlights of research on plant-derived natural products and their analogs with antitumor, anti-HIV, and antifungal activity
6. Antitumor agents 197. Novel antitumor agents from higher plants
7. Antitumor agents 176. Plant-derived anticancer agents and their analogs currently in clinical use or in clinical trials
8. The pharmacology of kampo prescriptions
9. Qualification of extract-preparations of Chinese drug prescriptions
10. Determination of ginsenosides in plant extracts from Panax ginseng and Panax quinquefolius L. by LC/MS/MS
11. Choto-san in the treatment of vascular dementia
12. Effect of oxindole alkaloids from the hooks of Uncaria macrophylla on thiopental-induced hypnosis
13. Traditional experience of Chinese herb medicine, its application in drug research and new drug searching
14. Antitumor activities of indirubin derivatives
15. Antimalarial agents 5. Synthesis of desethanoquinghaosu, a novel analogue of the antimalarial qinghaosu
16. Antimalarial artemisinin analogs: Synthesis of 2,3-desethano-12-deoxoartemisinin-related compounds
17. Acid degradation products of qinghaosu and their structure-activity relationships
18. Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminta
19. Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues
20. SK&F 104864, a water-soluble analog of camptothecin with broad spectrum activity in preclinical tumor models
21. Camptothecins: Dose-limiting toxicities and their management
22. Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer
23. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
24. Antitumor agents 153. Synthesis of novel water-soluble 7-(aminoacyl-hydrazono)-formyl camptothecins with potent inhibition of DNA topoisomerase I
25. From the study of Fructus schizandrae to the discovery of biphenyl-dimethyl-dicarboxylate
26. The structures of huperzines A and B, two new alkaloids exhibiting marked anti-cholinesterase activity
27. Effects of anisodine and other cholinergic drugs on conditioned response of the hippocampal theta rhythm in rabbits
28. Effects of anisodine on EEG and behavior of cats
29. Chemical studies on Erycibe obtusfolia. Bao Gong Teng. I: Isolation and preliminary study on a new myotic constituent Bao Gong Teng A
30. Studies on synthesis of baogongteng A - A new myotic agent
31. Studies on the active principals of the root yuan-hua. Isolation and structure of yuan hua fine
32. Effects of yuanhuacine and yuanhuadine on in vitro uterine contraction in rat
33. Antitumor agents 56: The protein synthesis inhibition by genkwadaphnin and yuanhuacine of P-388 lymphocytic leukemia cells
34. Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium against ischemia-induced derangements
35. Recent advances in the discovery and development of plant-derived natural products and their analogs as anti-HIV agents
36. Metabolism of plant-derived anticancer agents
37. Synthesis and antimitotic activity of glycosidic lignan derivatives related to podophyllotoxin
38. Teniposide: A review of 12 years of experience
39. Antitumor agents 113. New 4β-arylamino derivatives of 4′-demethylepipodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II
40. Antitumor agents 170. Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents
41. Anti-tumor promoting activities of kampo prescriptions. II. Inhibitory effects of souseiryu-to on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors
42. Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. 2. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum
43. Effect of breviscapin on plasma TXB2, 6-keto-PGFa, and platelet aggregation in experimental acute myocardial ischemia
44. Effects of di-ao-xin-xue-kong on coronary heart disease with left ventricular function and hemodynamics
45. The kinetic effects on blood flow of su-xiao-jiu-xin-wan and jiu-sin-tau
46. A comparative study on anti-inflammatory activities of the enantiomers, shikonin and alkannin
47. Isolation of deoxyshikonin, an antidermatophytic principal from Lithospermum erythrorhizon cell cultures
48. Anti-tumor promoting activities and inhibitory effects on Epstein-Barr virus activation of shi-un-kou and its constituents
49. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema
50. Treatment of irritable bowel syndrome with Chinese herbal medicine: A randomized controlled trial
51. Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor