Suppression of hepatitis C virus by the flavonoid quercetin is mediated by inhibition of NS3 protease activity

Journal of Viral Hepatitis

Volumn 19, Issue 2, 2012, Pages

  Bachmetov, L ^a   Gal Tanamy, M ^a   Shapira, A ^a   Vorobeychik, M ^a   Giterman Galam, T ^a   Sathiyamoorthy, P ^b   Golan Goldhirsh, A ^c   Benhar, I ^a   Tur Kaspa, R ^a,d   Zemel, R ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b Gem Research Foundation   (India)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d RABIN MEDICAL CENTER   (Israel)

Author keywords

flavonoid; hepatitis C virus; NS3 serine protease; quercetin

Indexed keywords

EMBELIA RIBES EXTRACT; NONSTRUCTURAL PROTEIN 3; PLANT EXTRACT; QUERCETIN; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EMBELIA RIBES; ENZYME ACTIVITY; ENZYME INHIBITION; HEPATITIS C VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT SEED; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPLICON; RNA REPLICATION; VIRUS GENOME; VIRUS INHIBITION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBELIA; HEPACIVIRUS; HUMANS; PLANT EXTRACTS; PROTEASE INHIBITORS; QUERCETIN; REAL-TIME POLYMERASE CHAIN REACTION; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84855834570     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2011.01507.x     Document Type: Article

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