메뉴 건너뛰기




Volumn 16, Issue 11, 2012, Pages 2813-2826

Topical application of phosphatidyl-inositol-3,5-bisphosphate for acute lung injury in neonatal swine

Author keywords

Apoptosis; Ceramide; Epithelial growth factors; Fibrosis; Macrophages

Indexed keywords

AMPHIREGULIN; CD14 ANTIGEN; CD18 ANTIGEN; CERAMIDE; GLYCOPROTEIN; IMIPRAMINE; INTERLEUKIN 6; LUNG SURFACTANT; PHOSPHATIDYLINOSITOL 3,5 DIPHOSPHATE; PHOSPHATIDYLINOSITOL 3,5-DIPHOSPHATE; POLYPHOSPHOINOSITIDE; SIGNAL PEPTIDE; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84868090810     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2012.01618.x     Document Type: Article
Times cited : (9)

References (60)
  • 1
    • 43449127011 scopus 로고    scopus 로고
    • Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia
    • Husari AW, Dbaibo GS, Bitar H, et al. Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia. Respir Res. 2006; 7: 100/1-11.
    • (2006) Respir Res , vol.7
    • Husari, A.W.1    Dbaibo, G.S.2    Bitar, H.3
  • 2
    • 44449165512 scopus 로고    scopus 로고
    • Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model
    • von Bismarck P, García Wistädt C-F, Klemm K, et al. Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model. Am J Respir Crit Care Med. 2008; 177: 1233-41.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1233-1241
    • von Bismarck, P.1    García Wistädt, C.-F.2    Klemm, K.3
  • 3
    • 0034811669 scopus 로고    scopus 로고
    • Sphingomyelin metabolites inhibit sphingomyelin synthase and CTP: phosphocholine cytidylyltransferase
    • Vivekananda J, Smith D, King RJ. Sphingomyelin metabolites inhibit sphingomyelin synthase and CTP: phosphocholine cytidylyltransferase. Am J Physiol Lung Cell Mol Physiol. 2001; 281: L98-107.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Vivekananda, J.1    Smith, D.2    King, R.J.3
  • 4
    • 0037214084 scopus 로고    scopus 로고
    • Aleveolar sphingolipids generated in response to TNF-alpha modifies surfactant biophysical properties
    • Ryan AJ, McCoy DM, McGowan SE, et al. Aleveolar sphingolipids generated in response to TNF-alpha modifies surfactant biophysical properties. J Appl Physiol. 2003; 94: 253-8.
    • (2003) J Appl Physiol , vol.94 , pp. 253-258
    • Ryan, A.J.1    McCoy, D.M.2    McGowan, S.E.3
  • 5
    • 11144354259 scopus 로고    scopus 로고
    • PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide
    • Göggel R, Winoto-Morbach S, Vielhaber G, et al. PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat Med. 2004; 10: 155-60.
    • (2004) Nat Med , vol.10 , pp. 155-160
    • Göggel, R.1    Winoto-Morbach, S.2    Vielhaber, G.3
  • 6
    • 2442661614 scopus 로고    scopus 로고
    • Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and caspase-3 activation
    • Heinrich M, Neumeyer J, Jakob M, et al. Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and caspase-3 activation. Cell Death Differ. 2004; 11: 550-63.
    • (2004) Cell Death Differ , vol.11 , pp. 550-563
    • Heinrich, M.1    Neumeyer, J.2    Jakob, M.3
  • 7
    • 0034046553 scopus 로고    scopus 로고
    • Ceramide path in human lung cell death
    • Chan C, Goldkorn T. Ceramide path in human lung cell death. Am J Respir Cell Mol Biol. 2000; 22: 460-8.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 460-468
    • Chan, C.1    Goldkorn, T.2
  • 8
    • 34547115448 scopus 로고    scopus 로고
    • Our fabulous vacation: a decade of phosphatidylinositol 3,5-bisphosphate
    • Dove SK, Johnson ZE. Our fabulous vacation: a decade of phosphatidylinositol 3, 5-bisphosphate. Biochem Soc Symp. 2007; 74: 129-39.
    • (2007) Biochem Soc Symp , vol.74 , pp. 129-139
    • Dove, S.K.1    Johnson, Z.E.2
  • 9
    • 30944461203 scopus 로고    scopus 로고
    • Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
    • Michell RH, Heath VL, Lemmon MA, et al. Phosphatidylinositol 3, 5-bisphosphate: metabolism and cellular functions. Trends Biochem Sci. 2006; 31: 52-63.
    • (2006) Trends Biochem Sci , vol.31 , pp. 52-63
    • Michell, R.H.1    Heath, V.L.2    Lemmon, M.A.3
  • 10
    • 17544390315 scopus 로고    scopus 로고
    • Phosphatidylinositol-3,5-bisphosphate is a potent and selective inhibitor of acid sphingomyelinase
    • Kölzer M, Arenz C, Ferlinz K, et al. Phosphatidylinositol-3, 5-bisphosphate is a potent and selective inhibitor of acid sphingomyelinase. Biol Chem. 2003; 384: 1293-8.
    • (2003) Biol Chem , vol.384 , pp. 1293-1298
    • Kölzer, M.1    Arenz, C.2    Ferlinz, K.3
  • 11
    • 70349995082 scopus 로고    scopus 로고
    • Potent and selective inhibition of acid sphingomyelinase by bisphosphonates
    • Roth AG, Drescher D, Yang Y, et al. Potent and selective inhibition of acid sphingomyelinase by bisphosphonates. Angew Chem Int Ed. 2009; 48: 7560-3.
    • (2009) Angew Chem Int Ed , vol.48 , pp. 7560-7563
    • Roth, A.G.1    Drescher, D.2    Yang, Y.3
  • 12
    • 0034990263 scopus 로고    scopus 로고
    • Alveolar recruitment promotes homogeneous surfactant distribution in a piglet model of lung injury
    • Krause MF, Jäkel C, Haberstroh J, et al. Alveolar recruitment promotes homogeneous surfactant distribution in a piglet model of lung injury. Pediatr Res. 2001; 50: 34-43.
    • (2001) Pediatr Res , vol.50 , pp. 34-43
    • Krause, M.F.1    Jäkel, C.2    Haberstroh, J.3
  • 13
    • 26444438658 scopus 로고    scopus 로고
    • Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
    • Claus RA, Bunck AC, Bockmeyer CL, et al. Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis. FASEB J. 2005; 19: 1719-21.
    • (2005) FASEB J , vol.19 , pp. 1719-1721
    • Claus, R.A.1    Bunck, A.C.2    Bockmeyer, C.L.3
  • 14
    • 33745352069 scopus 로고    scopus 로고
    • The E-method: a highly accurate technique for gene-expression analysis
    • Published online 21 June 2006. doi: 10.1038/NMETH894
    • Tellmann G. The E-method: a highly accurate technique for gene-expression analysis. Nat Meth. 2006; 3. Published online 21 June 2006. doi: 10.1038/NMETH894.
    • (2006) Nat Meth , vol.3
    • Tellmann, G.1
  • 15
    • 0028108015 scopus 로고
    • Functional dichotomy of neutral and acidic sphingomyelinase in tumor necrosis factor signaling
    • Wiegmann K, Schütze S, Machleidt T, et al. Functional dichotomy of neutral and acidic sphingomyelinase in tumor necrosis factor signaling. Cell. 1994; 78: 1005-15.
    • (1994) Cell , vol.78 , pp. 1005-1015
    • Wiegmann, K.1    Schütze, S.2    Machleidt, T.3
  • 16
    • 0343415084 scopus 로고    scopus 로고
    • Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier
    • Jensen JM, Schütze S, Förl M, et al. Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier. J Clin Invest. 1999; 104: 1761-70.
    • (1999) J Clin Invest , vol.104 , pp. 1761-1770
    • Jensen, J.M.1    Schütze, S.2    Förl, M.3
  • 18
    • 38849125645 scopus 로고    scopus 로고
    • Surfactant-replacement therapy for respiratory distress in the preterm and term neonate
    • Committee on Fetus and Newborn
    • Engle WA, Committee on Fetus and Newborn. Surfactant-replacement therapy for respiratory distress in the preterm and term neonate. Pediatrics. 2008; 121: 419-32.
    • (2008) Pediatrics , vol.121 , pp. 419-432
    • Engle, W.A.1
  • 19
    • 19944431657 scopus 로고    scopus 로고
    • Effect of exogenous surfactant (calfactant) in pediatric acute lung injury
    • Willson DF, Thomas NJ, Markovitz BP, et al. Effect of exogenous surfactant (calfactant) in pediatric acute lung injury. JAMA. 2005; 293: 470-6.
    • (2005) JAMA , vol.293 , pp. 470-476
    • Willson, D.F.1    Thomas, N.J.2    Markovitz, B.P.3
  • 20
    • 79954596013 scopus 로고    scopus 로고
    • Recombinant surfactant protein C-based surfactant for patients with severe direct lung injury
    • Spragg RG, Taut FJ, Lewis JF, et al. Recombinant surfactant protein C-based surfactant for patients with severe direct lung injury. Am J Respir Crit Care Med. 2011; 183: 1055-61.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1055-1061
    • Spragg, R.G.1    Taut, F.J.2    Lewis, J.F.3
  • 21
    • 0034529050 scopus 로고    scopus 로고
    • How cells handle cholesterol
    • Simons K, Ikonen E. How cells handle cholesterol. Science. 2000; 290: 1721-6.
    • (2000) Science , vol.290 , pp. 1721-1726
    • Simons, K.1    Ikonen, E.2
  • 22
    • 0036303786 scopus 로고    scopus 로고
    • The therapeutic potential of modulating the ceramide/sphingomyelin pathway
    • Kolesnick R. The therapeutic potential of modulating the ceramide/sphingomyelin pathway. J Clin Invest. 2002; 110: 3-8.
    • (2002) J Clin Invest , vol.110 , pp. 3-8
    • Kolesnick, R.1
  • 23
    • 0035877706 scopus 로고    scopus 로고
    • Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cellular granule cells developing in vitro
    • Prinetti A, Chigorno V, Prioni S, et al. Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cellular granule cells developing in vitro. J Biol Chem. 2001; 276: 21136-45.
    • (2001) J Biol Chem , vol.276 , pp. 21136-21145
    • Prinetti, A.1    Chigorno, V.2    Prioni, S.3
  • 24
    • 0031134930 scopus 로고    scopus 로고
    • Sphingomyelin metabolism is developmentally regulated in rat lung
    • Longo CA, Tyler D, Mallampalli RK. Sphingomyelin metabolism is developmentally regulated in rat lung. Am J Respir Cell Mol Biol. 1997; 16: 605-12.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 605-612
    • Longo, C.A.1    Tyler, D.2    Mallampalli, R.K.3
  • 25
    • 82855164062 scopus 로고    scopus 로고
    • The influence of developmental age on the early transcriptomic response of children with septic shock
    • Wynn JL, Cvijanovich NZ, Allen GL, et al. The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med. 2011; 17: 1146-56.
    • (2011) Mol Med , vol.17 , pp. 1146-1156
    • Wynn, J.L.1    Cvijanovich, N.Z.2    Allen, G.L.3
  • 26
    • 79959935032 scopus 로고    scopus 로고
    • Innate immune cell recruitment in the fetus and neonate
    • Nussbaum C, Sperandio M. Innate immune cell recruitment in the fetus and neonate. J Reprod Immunol. 2011; 90: 74-81.
    • (2011) J Reprod Immunol , vol.90 , pp. 74-81
    • Nussbaum, C.1    Sperandio, M.2
  • 27
    • 0034268524 scopus 로고    scopus 로고
    • Distribution of acid sphingomyelinase in human various body fluids
    • Takahashi I, Takahashi T, Abe T, et al. Distribution of acid sphingomyelinase in human various body fluids. Tohoku J Exp Med. 2000; 192: 61-6.
    • (2000) Tohoku J Exp Med , vol.192 , pp. 61-66
    • Takahashi, I.1    Takahashi, T.2    Abe, T.3
  • 28
    • 0035893581 scopus 로고    scopus 로고
    • The Phox homology (PX) domain, a new player in phosphoinositide signalling
    • Xu Y, Seet L-F, Hanson B, et al. The Phox homology (PX) domain, a new player in phosphoinositide signalling. Biochem J. 2001; 360: 513-30.
    • (2001) Biochem J , vol.360 , pp. 513-530
    • Xu, Y.1    Seet, L.-F.2    Hanson, B.3
  • 29
    • 77249112320 scopus 로고    scopus 로고
    • A specific phospholipase C activity regulates phosphatidylinositol levels in lung surfactant of patients with acute respiratory distress syndrome
    • Spyridakis S, Leondaritis G, Nakos G, et al. A specific phospholipase C activity regulates phosphatidylinositol levels in lung surfactant of patients with acute respiratory distress syndrome. Am J Respir Cell Mol Biol. 2010; 42: 357-62.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 357-362
    • Spyridakis, S.1    Leondaritis, G.2    Nakos, G.3
  • 30
    • 33646247181 scopus 로고    scopus 로고
    • Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels
    • Duex JE, Nau JJ, Kauffman EJ, et al. Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3, 5-bisphosphate levels. Eucaryot Cell. 2006; 5: 723-31.
    • (2006) Eucaryot Cell , vol.5 , pp. 723-731
    • Duex, J.E.1    Nau, J.J.2    Kauffman, E.J.3
  • 31
    • 77957553248 scopus 로고    scopus 로고
    • Cleaved caspase-3 in lung epithelium of children who died with acute respiratory distress syndrome
    • Bern RA, van der Loss CM, van Woensel JBM, et al. Cleaved caspase-3 in lung epithelium of children who died with acute respiratory distress syndrome. Pediatr Crit Care Med. 2010; 11: 556-60.
    • (2010) Pediatr Crit Care Med , vol.11 , pp. 556-560
    • Bern, R.A.1    van der Loss, C.M.2    van Woensel, J.B.M.3
  • 32
    • 1642474364 scopus 로고    scopus 로고
    • Apoptosis in lung development and neonatal lung injury
    • del Riccio V, van Tuyl M, Post M. Apoptosis in lung development and neonatal lung injury. Pediatr Res. 2004; 55: 183-9.
    • (2004) Pediatr Res , vol.55 , pp. 183-189
    • del Riccio, V.1    van Tuyl, M.2    Post, M.3
  • 34
    • 0032993972 scopus 로고    scopus 로고
    • Cyclic stretch induces both apoptosis and secretion in rat alveolar type II cells
    • Edwards YS, Sutherland LM, Power JHT, et al. Cyclic stretch induces both apoptosis and secretion in rat alveolar type II cells. FEBS Lett. 1999; 448: 127-30.
    • (1999) FEBS Lett , vol.448 , pp. 127-130
    • Edwards, Y.S.1    Sutherland, L.M.2    Power, J.H.T.3
  • 35
    • 0035076715 scopus 로고    scopus 로고
    • Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice
    • Kitamura Y, Hashimoto S, Mizuta N, et al. Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide-induced lung injury in mice. Am J Respir Crit Care Med. 2001; 163: 762-9.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 762-769
    • Kitamura, Y.1    Hashimoto, S.2    Mizuta, N.3
  • 36
    • 78751622827 scopus 로고    scopus 로고
    • Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes
    • Edelmann B, Bertsch U, Tchikov V, et al. Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes. EMBO J. 2011; 30: 379-94.
    • (2011) EMBO J , vol.30 , pp. 379-394
    • Edelmann, B.1    Bertsch, U.2    Tchikov, V.3
  • 37
    • 0141885959 scopus 로고    scopus 로고
    • Science review: apoptosis in acute lung injury
    • Matute-Bello G, Martin TR. Science review: apoptosis in acute lung injury. Crit Care. 2003; 7: 355-8.
    • (2003) Crit Care , vol.7 , pp. 355-358
    • Matute-Bello, G.1    Martin, T.R.2
  • 38
    • 16244379186 scopus 로고    scopus 로고
    • Influence of depletion of alveolar macrophages on apoptosis in Candida-induced acute lung injury
    • Takemura Y, Iwasaki Y, Nagata K, et al. Influence of depletion of alveolar macrophages on apoptosis in Candida-induced acute lung injury. Exp Lung Res. 2005; 31: 307-21.
    • (2005) Exp Lung Res , vol.31 , pp. 307-321
    • Takemura, Y.1    Iwasaki, Y.2    Nagata, K.3
  • 39
    • 78650057959 scopus 로고    scopus 로고
    • Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages
    • Petrusca DN, Gu Y, Adamowicz JJ, et al. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem. 2010; 285: 40322-32.
    • (2010) J Biol Chem , vol.285 , pp. 40322-40332
    • Petrusca, D.N.1    Gu, Y.2    Adamowicz, J.J.3
  • 40
    • 67349132318 scopus 로고    scopus 로고
    • Regulators of endothelial and epithelial barrier integrity and function in acute lung injury
    • Lucas R, Verin AD, Black SM, et al. Regulators of endothelial and epithelial barrier integrity and function in acute lung injury. Biochem Pharmacol. 2009; 77: 1763-72.
    • (2009) Biochem Pharmacol , vol.77 , pp. 1763-1772
    • Lucas, R.1    Verin, A.D.2    Black, S.M.3
  • 41
    • 0035006544 scopus 로고    scopus 로고
    • Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14
    • Maus U, Herold S, Muth H, et al. Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14. Am J Physiol Lung Cell Mol Physiol. 2001; 280: L58-68.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Maus, U.1    Herold, S.2    Muth, H.3
  • 42
    • 0034658632 scopus 로고    scopus 로고
    • Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis
    • Frevert CW, Matute-Bello G, Skerrett SJ, et al. Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis. J Immunol. 2000; 164: 5439-45.
    • (2000) J Immunol , vol.164 , pp. 5439-5445
    • Frevert, C.W.1    Matute-Bello, G.2    Skerrett, S.J.3
  • 43
    • 0032533842 scopus 로고    scopus 로고
    • The role of leukocyte emigration and IL-8 on the development of lipopolysaccharide-induced lung injury in rabbits
    • Yamamoto T, Kajikawa O, Martin TR, et al. The role of leukocyte emigration and IL-8 on the development of lipopolysaccharide-induced lung injury in rabbits. J Immunol. 1998; 161: 5704-9.
    • (1998) J Immunol , vol.161 , pp. 5704-5709
    • Yamamoto, T.1    Kajikawa, O.2    Martin, T.R.3
  • 44
    • 84860255381 scopus 로고    scopus 로고
    • Models and mechanisms of acute lung injury caused by direct insults
    • Reiss LK, Uhlig U, Uhlig S. Models and mechanisms of acute lung injury caused by direct insults. Eur J Cell Biol. 2012; 91: 590-601.
    • (2012) Eur J Cell Biol , vol.91 , pp. 590-601
    • Reiss, L.K.1    Uhlig, U.2    Uhlig, S.3
  • 45
    • 33745660525 scopus 로고    scopus 로고
    • Gene expression profiling of target genes in ventilator-induced lung injury
    • Dolinay T, Kaminski N, Felgendreher M, et al. Gene expression profiling of target genes in ventilator-induced lung injury. Physiol Genomics. 2006; 26: 68-75.
    • (2006) Physiol Genomics , vol.26 , pp. 68-75
    • Dolinay, T.1    Kaminski, N.2    Felgendreher, M.3
  • 46
    • 65249093700 scopus 로고    scopus 로고
    • Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury
    • Spieth PM, Carvalho AR, Pelosi P, et al. Variable tidal volumes improve lung protective ventilation strategies in experimental lung injury. Am J Respir Crit Care Med. 2009; 179: 684-93.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 684-693
    • Spieth, P.M.1    Carvalho, A.R.2    Pelosi, P.3
  • 47
    • 0038485575 scopus 로고    scopus 로고
    • TGF-β1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production
    • Chen H-H, Zhao S, Song J-G. TGF-β1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production. Cell Death Differ. 2003; 10: 516-27.
    • (2003) Cell Death Differ , vol.10 , pp. 516-527
    • Chen, H.-H.1    Zhao, S.2    Song, J.-G.3
  • 48
    • 0037383998 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome. A role for transforming growth factor-1β
    • Fahy RJ, Lichtenberger F, McKeegan CB, et al. The acute respiratory distress syndrome. A role for transforming growth factor-1β. Am J Respir Cell Mol Biol. 2003; 28: 499-503.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 499-503
    • Fahy, R.J.1    Lichtenberger, F.2    McKeegan, C.B.3
  • 49
    • 12944304176 scopus 로고    scopus 로고
    • Active transforming growth factor-β1 activates the procollagen I promotor in patients with acute lung injury
    • Budinger GRS, Chandel NS, Donnelly HK, et al. Active transforming growth factor-β1 activates the procollagen I promotor in patients with acute lung injury. Intensive Care Med. 2005; 31: 121-8.
    • (2005) Intensive Care Med , vol.31 , pp. 121-128
    • Budinger, G.R.S.1    Chandel, N.S.2    Donnelly, H.K.3
  • 50
    • 0031762920 scopus 로고    scopus 로고
    • Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I-symporter messenger ribonucleic acid levels in FRTL-5 cells
    • Pekary AE, Hershman JM. Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I-symporter messenger ribonucleic acid levels in FRTL-5 cells. Endocrinology. 1998; 139: 703-12.
    • (1998) Endocrinology , vol.139 , pp. 703-712
    • Pekary, A.E.1    Hershman, J.M.2
  • 51
    • 78049484309 scopus 로고    scopus 로고
    • Recruitment maneuver in experimental acute lung injury: the role of alveolar collapse and edema
    • Santiago VR, Rzezinski AF, Nardelli LM, et al. Recruitment maneuver in experimental acute lung injury: the role of alveolar collapse and edema. Crit Care Med. 2010; 38: 2207-14.
    • (2010) Crit Care Med , vol.38 , pp. 2207-2214
    • Santiago, V.R.1    Rzezinski, A.F.2    Nardelli, L.M.3
  • 52
    • 84860510967 scopus 로고    scopus 로고
    • Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6
    • Birukova AA, Tian Y, Meliton AY, et al. Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6. Am J Physiol Lung Cell Mol Physiol. 2012; 302: L965-75.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302
    • Birukova, A.A.1    Tian, Y.2    Meliton, A.Y.3
  • 53
    • 79959568466 scopus 로고    scopus 로고
    • Local apoptosis promotes collagen production by monocyte-driven cells in transforming growth factor β1-induced lung fibrosis
    • Peng X, Mathai SK, Murray LA, et al. Local apoptosis promotes collagen production by monocyte-driven cells in transforming growth factor β1-induced lung fibrosis. Fibrogenesis Tissue Repair. 2011; 4: 12-25.
    • (2011) Fibrogenesis Tissue Repair , vol.4 , pp. 12-25
    • Peng, X.1    Mathai, S.K.2    Murray, L.A.3
  • 54
    • 33644836488 scopus 로고    scopus 로고
    • Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity
    • Sparkman L, Chandru H, Boggaram V. Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity. Am J Physiol Lung Cell Mol Physiol. 2006; 290: L351-8.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Sparkman, L.1    Chandru, H.2    Boggaram, V.3
  • 55
    • 18744369317 scopus 로고    scopus 로고
    • Ceramide alters endothelial cell permeability by a nonapoptotic mechanism
    • Lindner L, Uhlig U, Uhlig S. Ceramide alters endothelial cell permeability by a nonapoptotic mechanism. Br J Pharmacol. 2005; 145: 132-40.
    • (2005) Br J Pharmacol , vol.145 , pp. 132-140
    • Lindner, L.1    Uhlig, U.2    Uhlig, S.3
  • 56
    • 77953544426 scopus 로고    scopus 로고
    • Protective effects of imipramine in murine endotoxin-induced acute lung injury
    • Yang J, Qu J, Summah H, et al. Protective effects of imipramine in murine endotoxin-induced acute lung injury. Eur J Pharmacol. 2010; 638: 128-33.
    • (2010) Eur J Pharmacol , vol.638 , pp. 128-133
    • Yang, J.1    Qu, J.2    Summah, H.3
  • 57
    • 84864529963 scopus 로고    scopus 로고
    • Inositol-trisposphate reduces alveolar apoptosis and pulmonary edema in neonatal lung injury
    • Preuß S, Stadelmann S, Omam FD, et al. Inositol-trisposphate reduces alveolar apoptosis and pulmonary edema in neonatal lung injury. Am J Respir Cell Mol Biol. 2012; 47: 158-69.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , pp. 158-169
    • Preuß, S.1    Stadelmann, S.2    Omam, F.D.3
  • 58
    • 0037370824 scopus 로고    scopus 로고
    • Alveolar lipoproteinosis in an acid sphingomyelinase-deficient mouse model of Niemann-Pick disease
    • Ikegami M, Dhami R, Schuchman EH. Alveolar lipoproteinosis in an acid sphingomyelinase-deficient mouse model of Niemann-Pick disease. Am J Physiol Lung Cell Mol Physiol. 2003; 284: L518-25.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Ikegami, M.1    Dhami, R.2    Schuchman, E.H.3
  • 59
    • 72849108236 scopus 로고    scopus 로고
    • Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells
    • Zhang Y, Duan R-D. Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells. Lipids Health Dis. 2009; 8: 51.
    • (2009) Lipids Health Dis , vol.8 , pp. 51
    • Zhang, Y.1    Duan, R.-D.2
  • 60
    • 42649101669 scopus 로고    scopus 로고
    • The angiotensin receptor type 1-Gq protein-phosphatidylinositol phospholipase Cβ-protein kinase C pathway is involved in activation of proximal tubule Na+-ATPase activity by angiotensin(1-7) in pig kidneys
    • Lara LS, Correa JS, Lavelle AB, et al. The angiotensin receptor type 1-Gq protein-phosphatidylinositol phospholipase Cβ-protein kinase C pathway is involved in activation of proximal tubule Na+-ATPase activity by angiotensin(1-7) in pig kidneys. Exp Physiol. 2008; 93: 639-47.
    • (2008) Exp Physiol , vol.93 , pp. 639-647
    • Lara, L.S.1    Correa, J.S.2    Lavelle, A.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.