-
2
-
-
58149147080
-
Infant mortality statistics from the 2005 period linked birth/infant death data set
-
Mathews TJ, MacDorman MF. (2008) Infant mortality statistics from the 2005 period linked birth/infant death data set. Natl. Vital Stat. Rep. 57:1-32.
-
(2008)
Natl. Vital Stat. Rep
, vol.57
, pp. 1-32
-
-
Mathews, T.J.1
Macdorman, M.F.2
-
3
-
-
14744298742
-
4 million neonatal deaths: When? where? why?
-
Lawn JE, Cousens S, Zupan J. (2005) 4 million neonatal deaths: when? where? why? Lancet 365:891-900.
-
(2005)
Lancet
, vol.365
, pp. 891-900
-
-
Lawn, J.E.1
Cousens, S.2
Zupan, J.3
-
4
-
-
60849101889
-
Myocardial transcriptional profiles in a murine model of sepsis: Evidence for the importance of age
-
Checchia PA, et al. (2008) Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age. Pediatr Crit. Care Med. 9:530-5.
-
(2008)
Pediatr Crit. Care Med
, vol.9
, pp. 530-535
-
-
Checchia, P.A.1
-
5
-
-
77951855187
-
The host response to sepsis and developmental impact
-
Wynn J, Cornell TT, Wong HR, Shanley TP, Wheeler DS. (2010) The host response to sepsis and developmental impact. Pediatrics. 125:1031-41.
-
(2010)
Pediatrics
, vol.125
, pp. 1031-1041
-
-
Wynn, J.1
Cornell, T.T.2
Wong, H.R.3
Shanley, T.P.4
Wheeler, D.S.5
-
6
-
-
47249122242
-
Validating the genomic signature of pediatric septic shock
-
Cvijanovich N, et al. (2008) Validating the genomic signature of pediatric septic shock. Physiol. Genomics. 34:127-34.
-
(2008)
Physiol. Genomics
, vol.34
, pp. 127-134
-
-
Cvijanovich, N.1
-
7
-
-
33847408050
-
Gene expression patterns in blood leukocytes discriminate patients with acute infections
-
Ramilo O, et al. (2007) Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood. 109:2066-77.
-
(2007)
Blood
, vol.109
, pp. 2066-2077
-
-
Ramilo, O.1
-
8
-
-
67650470273
-
Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum
-
Wong HR, et al. (2009) Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum. Crit. Care Med. 37:1558-66.
-
(2009)
Crit. Care Med
, vol.37
, pp. 1558-1566
-
-
Wong, H.R.1
-
9
-
-
70349239233
-
Identification of pediatric septic shock subclasses based on genome-wide expression profiling
-
Wong HR, et al. (2009) Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med. 7:34.
-
(2009)
BMC Med
, vol.7
, pp. 34
-
-
Wong, H.R.1
-
10
-
-
34547470882
-
Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome
-
Wong HR, et al. (2007) Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome. Physiol. Genomics 30:146-55.
-
(2007)
Physiol. Genomics
, vol.30
, pp. 146-155
-
-
Wong, H.R.1
-
11
-
-
21644438082
-
International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics
-
Goldstein B, Giroir B, Randolph A. (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr. Crit. Care Med. 6:2-8.
-
(2005)
Pediatr. Crit. Care Med
, vol.6
, pp. 2-8
-
-
Goldstein, B.1
Giroir, B.2
Randolph, A.3
-
12
-
-
35348925444
-
Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock
-
Shanley TP, et al. (2007) Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol. Med. 13:495-508.
-
(2007)
Mol. Med
, vol.13
, pp. 495-508
-
-
Shanley, T.P.1
-
13
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry RA, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 4:249-64.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
-
14
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano SE, et al. (2005) A network-based analysis of systemic inflammation in humans. Nature. 437:1032-7.
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
-
15
-
-
0344464733
-
Gene Expression Dynamics Inspector (GEDI): For integrative analysis of expression profiles
-
Eichler GS, Huang S, Ingber DE. (2003) Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles. Bioinformatics. 19:2321-2.
-
(2003)
Bioinformatics
, vol.19
, pp. 2321-2322
-
-
Eichler, G.S.1
Huang, S.2
Ingber, D.E.3
-
16
-
-
34247482586
-
Towards a holistic, yet gene-centered analysis of gene expression profiles: A case study of human lung cancers
-
Guo Y, Eichler GS, Feng Y, Ingber DE, Huang S. (2006) Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers. J. Biomed. Biotechnol. 2006:69141.
-
(2006)
J. Biomed. Biotechnol
, vol.2006
, pp. 69141
-
-
Guo, Y.1
Eichler, G.S.2
Feng, Y.3
Ingber, D.E.4
Huang, S.5
-
17
-
-
77957235521
-
Toward a clinically feasible gene expression-based subclassification strategy for septic shock: Proof of concept
-
Wong HR, et al. (2010) Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept. Crit. Care Med. 38:1955-61.
-
(2010)
Crit. Care Med
, vol.38
, pp. 1955-1961
-
-
Wong, H.R.1
-
18
-
-
77953516842
-
Pathophysiology and treatment of septic shock in neonates
-
Wynn JL, Wong HR. (2010) Pathophysiology and treatment of septic shock in neonates. Clin. Perinatol. 37:439-79.
-
(2010)
Clin. Perinatol
, vol.37
, pp. 439-479
-
-
Wynn, J.L.1
Wong, H.R.2
-
19
-
-
70349777300
-
Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
-
Belderbos ME, et al. (2009) Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life. Clin. Immunol. 133:228-37.
-
(2009)
Clin. Immunol
, vol.133
, pp. 228-237
-
-
Belderbos, M.E.1
-
20
-
-
73349130456
-
Neonatal innate TLRmediated responses are distinct from those of adults
-
Kollmann TR, et al. (2009) Neonatal innate TLRmediated responses are distinct from those of adults. J. Immunol. 183:7150-60.
-
(2009)
J. Immunol
, vol.183
, pp. 7150-7160
-
-
Kollmann, T.R.1
-
21
-
-
34247588114
-
Innate immunity of the newborn: Basic mechanisms and clinical correlates
-
Levy O. (2007) Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat. Rev. Immunol. 7:379-90.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 379-390
-
-
Levy, O.1
-
22
-
-
78650119848
-
Innate immunity in human newborn infants: Prematurity means more than immaturity
-
Strunk T, Currie A, Richmond P, Simmer K, Burgner D. (2011) Innate immunity in human newborn infants: prematurity means more than immaturity. J. Matern. Fetal. Neonatal. Med. 24:25-31.
-
(2011)
J. Matern. Fetal. Neonatal. Med
, vol.24
, pp. 25-31
-
-
Strunk, T.1
Currie, A.2
Richmond, P.3
Simmer, K.4
Burgner, D.5
-
23
-
-
77953522678
-
Role of innate host defenses in susceptibility to early-onset neonatal sepsis
-
Wynn JL, Levy O. (2010) Role of innate host defenses in susceptibility to early-onset neonatal sepsis. Clin. Perinatol. 37:307-37.
-
(2010)
Clin. Perinatol
, vol.37
, pp. 307-337
-
-
Wynn, J.L.1
Levy, O.2
-
24
-
-
0035953547
-
TREM-1 amplifies inflammation and is a crucial mediator of septic shock
-
Bouchon A, Facchetti F, Weigand MA, Colonna M. (2001) TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature. 410:1103-7.
-
(2001)
Nature
, vol.410
, pp. 1103-1107
-
-
Bouchon, A.1
Facchetti, F.2
Weigand, M.A.3
Colonna, M.4
-
25
-
-
36249028582
-
Increased mortality and alteredaltered immunity in neonatal sepsis produced by generalized peritonitis
-
Wynn JL, et al. (2007) Increased mortality and alteredaltered immunity in neonatal sepsis produced by generalized peritonitis. Shock. 28:675-83.
-
(2007)
Shock
, vol.28
, pp. 675-683
-
-
Wynn, J.L.1
-
27
-
-
52649156933
-
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists
-
Wynn JL, et al. (2008) Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood. 112:1750-8.
-
(2008)
Blood
, vol.112
, pp. 1750-1758
-
-
Wynn, J.L.1
-
28
-
-
5944251623
-
Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte
-
Hotchkiss RS, et al. (2000) Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat. Immunol. 1:496-501.
-
(2000)
Nat. Immunol
, vol.1
, pp. 496-501
-
-
Hotchkiss, R.S.1
-
29
-
-
27744464494
-
Prevention of lymphocyte apoptosis: A potential treatment of sepsis?
-
Hotchkiss RS, Coopersmith CM, Karl IE. (2005) Prevention of lymphocyte apoptosis: a potential treatment of sepsis? Clin. Infect. Dis. 41 Suppl 7:S465-9.
-
(2005)
Clin. Infect. Dis
, vol.41
, Issue.SUPPL. 7
-
-
Hotchkiss, R.S.1
Coopersmith, C.M.2
Karl, I.E.3
-
30
-
-
0842327458
-
Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review
-
Kalman L, et al. (2004) Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review. Genet. Med. 6:16-26.
-
(2004)
Genet. Med
, vol.6
, pp. 16-26
-
-
Kalman, L.1
-
31
-
-
59749100172
-
Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis
-
Wynn JL, Neu J, Moldawer LL, Levy O. (2009) Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis. J. Perinatol. 29:79-88.
-
(2009)
J. Perinatol
, vol.29
, pp. 79-88
-
-
Wynn, J.L.1
Neu, J.2
Moldawer, L.L.3
Levy, O.4
-
32
-
-
77957585989
-
Does IVIg administration yield improved immune function in very premature neonates?
-
Wynn JL, Seed PC, Cotten CM. (2010) Does IVIg administration yield improved immune function in very premature neonates? J. Perinatol. 30:635-42.
-
(2010)
J. Perinatol
, vol.30
, pp. 635-642
-
-
Wynn, J.L.1
Seed, P.C.2
Cotten, C.M.3
-
33
-
-
11844258296
-
CpG oligodeoxynucleotides enhance neonatal resistance to Listeria infection
-
Ito S, et al. (2005) CpG oligodeoxynucleotides enhance neonatal resistance to Listeria infection. J. Immunol. 174:777-82.
-
(2005)
J. Immunol
, vol.174
, pp. 777-782
-
-
Ito, S.1
-
34
-
-
33645777431
-
CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus
-
Pedras-Vasconcelos JA, et al. (2006) CpG oligodeoxynucleotides protect newborn mice from a lethal challenge with the neurotropic Tacaribe arenavirus. J. Immunol. 176:4940-9.
-
(2006)
J. Immunol
, vol.176
, pp. 4940-4949
-
-
Pedras-Vasconcelos, J.A.1
-
35
-
-
33845548419
-
Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/ RUNX1 mutation: Insights from platelet expression profiling
-
Sun L, Gorospe JR, Hoffman EP, Rao AK. (2007) Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/ RUNX1 mutation: insights from platelet expression profiling. J. Thromb. Haemost. 5:146-54.
-
(2007)
J. Thromb. Haemost
, vol.5
, pp. 146-154
-
-
Sun, L.1
Gorospe, J.R.2
Hoffman, E.P.3
Rao, A.K.4
-
36
-
-
77952314473
-
Leukocyte subset-derived genomewide expression profiles in pediatric septic shock
-
Wong HR, Freishtat RJ, Monaco M, Odoms K, Shanley TP. (2010) Leukocyte subset-derived genomewide expression profiles in pediatric septic shock. Pediatr. Crit. Care Med. 11:349-55.
-
(2010)
Pediatr. Crit. Care Med
, vol.11
, pp. 349-355
-
-
Wong, H.R.1
Freishtat, R.J.2
Monaco, M.3
Odoms, K.4
Shanley, T.P.5
|