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Angewandte Chemie - International Edition

Volumn 48, Issue 41, 2009, Pages 7560-7563

Potent and selective inhibition of acid sphingomyelinase by bisphosphonates

(6) Roth, Anke G a Drescher, Daniela a Yang, Yang b Reamer, Susanne a Uhlig, Stefan b Arenz, Christoph a

a HUMBOLDT UNIVERSITY (Germany)

b RWTH AACHEN UNIVERSITY (Germany)

Author keywords

Bloorganic chemistry; Blsphosphonates; Drug targets; Enzyme inhibitors; Sphlngoliplds

Indexed keywords

BLOORGANIC CHEMISTRY; BLSPHOSPHONATES; DRUG TARGETS; ENZYME INHIBITORS; SPHLNGOLIPLDS;

CELL DEATH; CELL MEMBRANES; ENZYMES; PULMONARY DISEASES; TARGETS;

ACIDS;

BISPHOSPHONIC ACID DERIVATIVE; ISOENZYME; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; FEMALE; HUMAN; METABOLISM; RAT; SYNTHESIS; WISTAR RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DIPHOSPHONATES; FEMALE; HUMANS; ISOENZYMES; MOLECULAR STRUCTURE; RATS; RATS, WISTAR; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 70349995082 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/anie.200903288 Document Type: Article

Times cited : (75)

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