Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis

Fibrogenesis and Tissue Repair

Volumn 4, Issue 1, 2011, Pages

  Peng, Xueyan ^a   Mathai, Susan K ^a   Murray, Lynne A ^b   Russell, Thomas ^a   Reilkoff, Ronald ^a   Chen, Qingsheng ^a   Gulati, Mridu ^a   Elias, Jack A ^a   Bucala, Richard ^a   Gan, Ye ^c   Herzog, Erica L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDIMMUNE   (United States)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CD45 ANTIGEN; COLLAGEN; TRANSFORMING GROWTH FACTOR BETA1;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL LINEAGE; CELL POPULATION; CLINICAL ARTICLE; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; FIBROSING ALVEOLITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL LUNG DISEASE; LEUKOCYTE; LUNG FIBROSIS; LUNG PARENCHYMA; MACROPHAGE; MALE; MONOCYTE; NONHUMAN;

EID: 79959568466     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/1755-1536-4-12     Document Type: Article

References (40)

1. Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol 2005, 5:953-964. 10.1038/nri1733, 16322748.
2. Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1994, 1:71-81. 2229929, 8790603.
3. Murray LA, Chen Q, Kramer MS, Hesson DP, Argentieri RL, Peng X, Gulati M, Homer RJ, Russell T, van Rooijen N, Elias JA, Hogaboam CM, Herzog EL. TGF-beta driven lung fibrosis is macrophage dependent and blocked by serum amyloid P. Int J Biochem Cell Biol 2011, 43:154-162. 10.1016/j.biocel.2010.10.013, 21044893.
4. Mehrad B, Burdick MD, Zisman DA, Keane MP, Belperio JA, Strieter RM. Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease. Biochem Biophys Res Commun 2007, 353:104-108. 10.1016/j.bbrc.2006.11.149, 17174272.
5. Wang CH, Huang CD, Lin HC, Lee KY, Lin SM, Liu CY, Huang KH, Ko YS, Chung KF, Kuo HP. Increased circulating fibrocytes in asthma with chronic airflow obstruction. Am J Respir Crit Care Med 2008, 178:583-591. 10.1164/rccm.200710-1557OC, 18583572.
6. Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest 90:812-823.
7. Pilling D, Fan T, Huang D, Kaul B, Gomer RH. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts. PLoS One 2009, 4:e7475. 10.1371/journal.pone.0007475, 2759556, 19834619.
8. Herzog EL, Bucala R. Fibrocytes in health and disease. Exp Hematol 2010, 38:548-556. 10.1016/j.exphem.2010.03.004, 20303382.
9. Chesney J, Metz C, Stavitsky AB, Bacher M, Bucala R. Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes. J Immunol 1998, 160:419-425.
10. Hashimoto NJH, Liu T, Chensue SW, Phan SH. Bone marrow derived progenitor cells in pulmonary fibrosis. J Clin Invest 2004, 113:243-252. 310750, 14722616.
11. Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Hepatol 2006, 45:429-438. 10.1016/j.jhep.2006.04.014, 16846660.
12. Phillips RJ, Burdick MD, Hong K, Lutz MA, Murray LA, Xue YY, Belperio JA, Keane MP, Strieter RM. Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J Clin Invest 2004, 114:438-446. 484979, 15286810.
13. Homer RJ, Elias JA, Lee CG, Herzog EL. Modern concepts in pulmonary fibrosis. Arch Pathol Lab Med
14. Luzina IG, Atamas SP, Wise R, Wigley FM, Xiao HQ, White B. Gene expression in bronchoalveolar lavage cells from scleroderma patients. Am J Respir Cell Mol Biol 2002, 26:549-557.
15. Anscher MS, Kong FM, Andrews K, Clough R, Marks LB, Bentel G, Jirtle RL. Plasma transforming growth factor beta1 as a predictor of radiation pneumonitis. Int J Radiat Oncol Biol Phys 1998, 41:1029-1035. 10.1016/S0360-3016(98)00154-0, 9719112.
16. Anscher MS, Kong FM, Jirtle RL. The relevance of transforming growth factor beta 1 in pulmonary injury after radiation therapy. Lung Cancer 1998, 19:109-120. 10.1016/S0169-5002(97)00076-7, 9567247.
17. Asano Y, Ihn H, Yamane K, Kubo M, Tamaki K. Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts. J Clin Invest 2004, 113:253-264. 310747, 14722617.
18. Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, Noble PW, Yehualaeshet T, Lu B, Flavell RA, Milbrandt J, Homer RJ, Elias JA. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med 2004, 200:377-389. 10.1084/jem.20040104, 2211975, 15289506.
19. Barbas-Filho JV, Ferreira MA, Sesso A, Kairalla RA, Carvalho CR, Capelozzi VL. Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol 2001, 54:132-138. 10.1136/jcp.54.2.132, 1731356, 11215282.
20. Kuwano K. Involvement of epithelial cell apoptosis in interstitial lung diseases. Intern Med 2008, 47:345-353. 10.2169/internalmedicine.47.0713, 18310962.
21. Andersson-Sjoland A, Erjefalt JS, Bjermer L, Eriksson L, Westergren-Thorsson G. Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis. Respir Res 2009, 10:103. 10.1186/1465-9921-10-103, 2774308, 19878544.
22. Jyonouchi H. Airway epithelium and apoptosis. Apotosis 1999, 4:4007-4417.
23. Broen J, Gourh P, Rueda B, Coenen M, Mayes M, Martin J, Arnett FC, Radstake TR. The FAS -670A > G polymorphism influences susceptibility to systemic sclerosis phenotypes. Arthritis Rheum 2009, 60:3815-3820. 10.1002/art.24964, 2876716, 19950259.
24. Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunol Rev 2004, 202:175-190. 10.1111/j.0105-2896.2004.00215.x, 15546393.
25. Gan Y, Reilkoff R, Peng X, Russell T, Chen Q, Mathai SK, Homer R, Gulati M, Siner J, Elias J, Bucala R, Herzog E. Role of semaphorin 7a in TGF-β1 induced lung fibrosis, fibrocyte differentiation, and scleroderma-related interstitial lung disease. Arthritis Rheum
26. Murray LA, Rosada R, Moreira AP, Joshi A, Kramer MS, Hesson DP, Argentieri RL, Mathai S, Gulati M, Herzog EL, Hogaboam CM. Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages. PLoS One 5:e9683.
27. Quan TE, Bucala R. Culture and analysis of circulating fibrocytes. Methods Mol Med 2007, 135:423-434. 10.1007/978-1-59745-401-8_28, 17951676.
28. Schmidt M, Sun G, Stacey MA, Mori L, Mattoli S. Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J Immunol 2003, 171:380-389.
29. Xiao M, Oppenlander BK, Dooley DC. Transforming growth factor-beta(1) induces apoptosis in CD34(+)CD38(-/low) cells that express Bcl-2 at a low level. Exp Hematol 2001, 29:1098-1108. 10.1016/S0301-472X(01)00680-4, 11532351.
30. Zhou L, Nguyen AN, Sohal D, Ying Ma J, Pahanish P, Gundabolu K, Hayman J, Chubak A, Mo Y, Bhagat TD, Das B, Kapoun AM, Navas TA, Parmar S, Kambhampati S, Pellagatti A, Braunchweig I, Zhang Y, Wickrema A, Medicherla S, Boultwood J, Platanias LC, Higgins LS, List AF, Bitzer M, Verma A. Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS. Blood 2008, 112:3434-3443. 10.1182/blood-2008-02-139824, 2569182, 18474728.
31. Chesney J, Bacher M, Bender A, Bucala R. The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci USA 1997, 94:6307-6312. 10.1073/pnas.94.12.6307, 21045, 9177213.
32. Hartlapp I, Abe R, Saeed RW, Peng T, Voelter W, Bucala R, Metz CN. Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo. FASEB J 2001, 15:2215-2224. 10.1096/fj.01-0049com, 11641248.
33. Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP. Macrophages produce TGF-beta-induced (beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14 levels and collagen turnover in fibroblasts. J Immunol 2008, 180:5036-5044. 2847349, 18354229.
34. Medeiros AI, Serezani CH, Lee SP, Peters-Golden M. Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling. J Exp Med 2009, 206:61-68. 10.1084/jem.20082058, 2626688, 19124657.
35. Pepys MB, Baltz M, Gomer K, Davies AJ, Doenhoff M. Serum amyloid P-component is an acute-phase reactant in the mouse. Nature 1979, 278:259-261. 10.1038/278259a0, 423976.
36. Butler PJ, Tennent GA, Pepys MB. Pentraxin-chromatin interactions: serum amyloid P component specifically displaces H1-type histones and solubilizes native long chromatin. J Exp Med 1990, 172:13-18. 10.1084/jem.172.1.13, 2188144, 2358775.
37. Moore BB, Murray L, Das A, Wilke CA, Herrygers AB, Toews GB. The role of CCL12 in the recruitment of fibrocytes and lung fibrosis. Am J Respir Cell Mol Biol 2006, 35:175-181. 10.1165/rcmb.2005-0239OC, 2643255, 16543609.
38. Xu J, Gonzalez ET, Iyer SS, Mac V, Mora AL, Sutliff RL, Reed A, Brigham KL, Kelly P, Rojas M. Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice. J Gerontol A Biol Sci Med Sci 2009, 64:731-739. 2844132, 19359440.
39. Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009, 27:451-483. 10.1146/annurev.immunol.021908.132532, 19105661.
40. American Thoracic Society, European Respiratory Society American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 2002, 165:277-304. American Thoracic Society, European Respiratory Society.