The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans

Molecular Microbiology

Volumn 86, Issue 3, 2012, Pages 539-556

  Sasse, Christoph ^a   Dunkel, Nico ^a   Schäfer, Tina ^a   Schneider, Sabrina ^a   Dierolf, Franziska ^a   Ohlsen, Knut ^a   Morschhäuser, Joachim ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUCONAZOLE; FUNGAL PROTEIN;

ANTIFUNGAL RESISTANCE; ARTICLE; CANDIDA ALBICANS; COMPETITIVE ABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ERG11 GENE; FUNGAL COLONIZATION; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE TARGETING; GENOME ANALYSIS; HETEROZYGOSITY LOSS; HOMOZYGOTE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; MRR1 GENE; NONHUMAN; PRIORITY JOURNAL; TAC1 GENE; UPC2 GENE; WILD TYPE;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; DRUG RESISTANCE, FUNGAL; FLUCONAZOLE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MUTATION; TRANSCRIPTION FACTORS;

CANDIDA ALBICANS; MAMMALIA;

EID: 84868087578     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2012.08210.x     Document Type: Article

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