A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate

Eukaryotic Cell

Volumn 7, Issue 7, 2008, Pages 1180-1190

  Dunkel, Nico ^a   Liu, Teresa T ^b   Barker, Katherine S ^b,c   Homayouni, Ramin ^d,e   Morschhäuser, Joachim ^a   Rogers, P David ^b,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c LE BONHEUR CHILDREN'S MEDICAL CENTER   (United States)

^d University of Memphis   (United States)

^e UNIVERSITY OF MEMPHIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ERGOSTEROL; FLUCONAZOLE; FUNGAL PROTEIN; TRANSCRIPTION FACTOR;

ANTIFUNGAL RESISTANCE; ARTICLE; BIOSYNTHESIS; CANDIDA ALBICANS; CANDIDIASIS; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MUTATION; STOP CODON; UPREGULATION;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; CODON, NONSENSE; DRUG RESISTANCE, FUNGAL; ERGOSTEROL; FLUCONAZOLE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MUTATION; TRANSCRIPTION FACTORS; UP-REGULATION;

CANDIDA ALBICANS;

EID: 47049101245     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00103-08     Document Type: Article

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