Evolution of drug resistance in experimental populations of Candida albicans

Journal of Bacteriology

Volumn 182, Issue 6, 2000, Pages 1515-1522

  Cowen, Leah E ^a   Sanglard, Dominique ^b   Calabrese, David ^b   Sirjusingh, Caroline ^a   Anderson, James B ^a   Kohn, Linda M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN; ANTIFUNGAL AGENT; ERGOSTEROL; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; PYRROLE DERIVATIVE;

ADAPTATION; ANTIBIOTIC RESISTANCE; ARTICLE; CANDIDA ALBICANS; GENE OVEREXPRESSION; HETEROZYGOSITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS, ORAL; COLONY COUNT, MICROBIAL; CULTURE MEDIA; DNA FINGERPRINTING; DRUG RESISTANCE, MICROBIAL; EVOLUTION, MOLECULAR; FLUCONAZOLE; HUMANS; KARYOTYPING; LOSS OF HETEROZYGOSITY; MICROBIAL SENSITIVITY TESTS; SEQUENCE ANALYSIS, DNA;

CANDIDA ALBICANS;

EID: 0034051543     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.6.1515-1522.2000     Document Type: Article

References (32)

1. Arjan, J. A., M. Visser, C. W. Zeyl, P. J. Gerrish, J. L. Blanchard, and R. E. Lenski. 1999. Diminishing returns from mutation supply rate in asexual populations. Science 283:404-406.
2. Ausubel, F. M. 1995. Preparation of yeast RNA, p. 13.12.2-13.12.3. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
3. Chu, W. S., B. B. Magee, and P. T. Magee. 1993. Construction of an SfiI macrorestriction map of the Candida albicans genome. J. Bacteriol. 175: 6637-6651.
4. Cowen, L. E., C. Sirjusingh, R. C. Summerbell, S. Walmsley, S. Richardson, L. M. Kohn, and J. B. Anderson. 1999. Multilocus genotypes and DNA fingerprints do not predict variation in azole resistance among clinical isolates of Candida albicans. Antimicrob. Agents Chemother. 12:2930-2938.
5. Ferea, T. L., D. Botstein, P. O. Brown, and R. F. Rosenzweig. 1999. Systematic changes in gene expression patterns following adaptive evolution in yeast. Proc. Natl. Acad. Sci. USA 96:9721-9726.
6. Gräser, Y., M. Volovsek, J. Arrington, G. Schönian, W. Presber, T. G. Mitchell, and R. Vilgalys. 1996. Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination. Proc. Natl. Acad. Sci. USA 93:12473-12477.
7. Hull, C. M., and A. D. Johnson. 1999. Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science 285:1271-1275.
8. Iwaguchi, S., M. Homma, and K. Tanaka. 1992. Clonal variation of chromosome size derived from the rDNA cluster region in Candida albicans. J. Gen. Microbiol. 138:1177-1184.
9. Lenski, R. E., and M. Travisano. 1994. Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations. Proc. Natl. Acad. Sci. USA 91:6808-6814.
10. Marr, K. A., T. R. Rustad, J. H. Rex, and T. C. White. 1999. The trailing end point phenotype in antifungal susceptibility testing is pH dependent. Antimicrob. Agents Chemother. 43:1383-1386.
11. Merz, W. G. 1990. Candida albicans strain delineation. Clin. Microbiol. Rev. 3:321-334.
12. National Committee for Clinical Laboratory Standards. 1997. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard, NCCLS document M27-A. National Committee for Clinical Laboratory Standards, Wayne, Pa.
13. Perepnikhatka, V., F. J. Fischer, M. Niimi, R. A. Baker, R. D. Cannon, Y. K. Wang, F. Sherman, and E. Rustchenko. 1999. Specific chromosome alterations in fluconazole-resistant mutants of Candida albicans. J. Bacteriol. 181:4041-4049.
14. Pujol, C., J. Reynes, F. Renaud, M. Raymond, M. Tibayrenc, F. J. Ayala, F. Janbon, M. Mallie, and J. M. Bastide. 1993. The yeast Candida albicans has a clonal mode of reproduction in a population of infected human immunodeficiency virus-positive patients. Proc. Natl. Acad. Sci. USA 90:9456-9459.
15. Rustchenko, E. P., T. M. Curran, and F. Sherman. 1993. Variations in the number of ribosomal DNA units in morphological mutants and normal strains of Candida albicans and in normal strains of Saccharomyces cerevisiae. J. Bacteriol. 175:7189-7199.
16. Rustchenko-Bulgac, E. P., F. Sherman, and J. B. Hicks. 1990. Chromosomal rearrangements associated with morphological mutants provide a means for genetic variation of Candida albicans. J. Bacteriol. 172:1276-1283.
17. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
18. Sanglard, D., F. Ischer, L. Koymans, and J. Bille. 1998. Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51Al) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob. Agents Chemother. 42:241-253.
19. Sanglard, D., F. Ischer, M. Monod, and J. Bille. 1997. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene. Microbiology 143: 405-416.
20. Sanglard, D., K. Kuchler, F. Ischer, J. L. Pagani, M. Monod, and J. Bille. 1995. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob. Agents Chemother. 39:2378-2386.
21. Saville, B. J., Y. Kohli, and J. B. Anderson. 1998. mtDNA recombination in a natural population. Proc. Natl. Acad. Sci. USA 95:1331-1335.
22. Scherer, S., and P. T. Magee. 1990. Genetics of Candida albicans. Microbiol. Rev. 54:226-241.
23. Scherer, S., and D. A. Stevens. 1987. Application of DNA typing methods to epidemiology and taxonomy of Candida species. J. Clin. Microbiol. 25:675-679.
24. Scherer, S., and D. A. Stevens. 1988. A Candida albicans dispersed, repeated gene family and its epidemiologic applications. Proc. Natl. Acad. Sci. USA 85:1452-1456.
25. Taylor, M., and R. Feyereisen. 1996. Molecular biology and evolution of resistance to toxicants. Mol. Biol. Evol. 13:719-734.
26. Travisano, M., J. A. Mongold, A. F. Bennett, and R. E. Lenski. 1995. Experimental tests of the roles of adaptation, chance, and history in evolution. Science 267:87-90.
27. White, T. C., K. A. Marr, and R. A. Bowden. 1998. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin. Microbiol. Rev. 11:382-402.
28. Wichman, H. A., M. R. Badgett, L. A. Scott, C. M. Boulianne, and J. J. Bull. 1999. Different trajectories of parallel evolution during viral adaptation. Science 285:422-424.
29. Williams, D. W., M. J. Wilson, M. A. Lewis, and A. J. Potts. 1995. Identification of Candida species by PCR and restriction fragment length polymorphism analysis of intergenic spacer regions of ribosomal DNA. J. Clin. Microbiol. 33:2476-2479.
30. Wright, S. 1982. Character change, speciation, and the higher taxa. Evolution 36:427-443.
31. Wright, S. 1988. Surfaces of selective value revisited. Am. Nat. 131:115-123.
32. Zeyl, C., and G. Bell. 1997. The advantage of sex in evolving yeast populations. Nature 388:465-468.