메뉴 건너뛰기




Volumn 5, Issue 5, 2012, Pages 710-721

Autophagy in adipose tissue

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ADIPONECTIN; AUTOPHAGY PROTEIN 5; BECLIN 1; GLUCOSE; INSULIN; INSULIN RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MAMMALIAN TARGET OF RAPAMYCIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PERILIPIN; PERILIPIN A; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT ADIPONECTIN; RECOMBINANT PROTEIN; THAPSIGARGIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84867899702     PISSN: 16624025     EISSN: 16624033     Source Type: Journal    
DOI: 10.1159/000343983     Document Type: Review
Times cited : (31)

References (64)
  • 1
    • 57849136841 scopus 로고    scopus 로고
    • Autophagy: Principles and significance in health and disease
    • Todde V, Veenhuis M, van der Klei IJ: Autophagy: principles and significance in health and disease. Biochim Biophys Acta 2009; 1792: 3-13.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 3-13
    • Todde, V.1    Veenhuis, M.2    Van Der Klei, I.J.3
  • 2
    • 79955631150 scopus 로고    scopus 로고
    • Autophagy in the cellular energetic balance
    • Singh R, Cuervo AM: Autophagy in the cellular energetic balance. Cell Metab 2011; 13: 495-504.
    • (2011) Cell Metab , vol.13 , pp. 495-504
    • Singh, R.1    Cuervo, A.M.2
  • 3
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • Levine B, Klionsky DJ: Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463-477. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 4
    • 24744441497 scopus 로고    scopus 로고
    • Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation
    • DOI 10.1074/jbc.M506736200
    • Onodera J, Ohsumi Y: Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem 2005; 280: 31582-31586. (Pubitemid 41291902)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.36 , pp. 31582-31586
    • Onodera, J.1    Ohsumi, Y.2
  • 5
    • 33749055522 scopus 로고    scopus 로고
    • Autophagy: A cell repair mechanism that retards ageing and age-associated diseases and can be intensified pharmacologically
    • DOI 10.1016/j.mam.2006.08.001, PII S0098299706000161
    • Bergamini E: Autophagy: a cell repair mechanism that retards ageing and age-associated diseases and can be intensified pharmacologically. Mol Aspects Med 2006; 27: 403-410. (Pubitemid 44466651)
    • (2006) Molecular Aspects of Medicine , vol.27 , Issue.5-6 , pp. 403-410
    • Bergamini, E.1
  • 6
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • DOI 10.1038/nature06639, PII NATURE06639
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069-1075. (Pubitemid 351317450)
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 7
    • 80053634368 scopus 로고    scopus 로고
    • The dynamic nature of autophagy in cancer
    • Kimmelman AC: The dynamic nature of autophagy in cancer. Genes Dev 2011; 25: 1999-2010.
    • (2011) Genes Dev , vol.25 , pp. 1999-2010
    • Kimmelman, A.C.1
  • 13
    • 73949124173 scopus 로고    scopus 로고
    • Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
    • Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S: Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci USA 2009; 106: 19860-19865.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19860-19865
    • Zhang, Y.1    Goldman, S.2    Baerga, R.3    Zhao, Y.4    Komatsu, M.5    Jin, S.6
  • 16
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • Mizushima N, Levine B: Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12: 823-830.
    • (2010) Nat Cell Biol , vol.12 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 17
    • 73449117508 scopus 로고    scopus 로고
    • Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
    • Baerga R, Zhang Y, Chen PH, Goldman S, Jin S: Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy 2009; 5: 1118-1130.
    • (2009) Autophagy , vol.5 , pp. 1118-1130
    • Baerga, R.1    Zhang, Y.2    Chen, P.H.3    Goldman, S.4    Jin, S.5
  • 18
    • 75149123563 scopus 로고    scopus 로고
    • Autophagy and adipogenesis: Implications in obesity and type II diabetes
    • Goldman S, Zhang Y, Jin S: Autophagy and adipogenesis: implications in obesity and type II diabetes. Autophagy 2010; 6: 179-181.
    • (2010) Autophagy , vol.6 , pp. 179-181
    • Goldman, S.1    Zhang, Y.2    Jin, S.3
  • 21
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
    • DOI 10.1210/er.21.6.697
    • Wajchenberg BL: Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000; 21: 697-738. (Pubitemid 32113289)
    • (2000) Endocrine Reviews , vol.21 , Issue.6 , pp. 697-738
    • Wajchenberg, B.L.1
  • 23
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity?
    • Trayhurn P, Wang B, Wood IS: Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 2008; 100: 227-235.
    • (2008) Br J Nutr , vol.100 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 24
    • 34548419344 scopus 로고    scopus 로고
    • Adipocyte stress: The endoplasmic reticulum and metabolic disease
    • DOI 10.1194/jlr.R700007-JLR200
    • Gregor MF, Hotamisligil GS: Thematic review series: adipocyte biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res 2007; 48: 1905-1914. (Pubitemid 47360610)
    • (2007) Journal of Lipid Research , vol.48 , Issue.9 , pp. 1905-1914
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 25
    • 70350188297 scopus 로고    scopus 로고
    • Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome
    • Maury E, Brichard SM: Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol 2010; 314: 1-16.
    • (2010) Mol Cell Endocrinol , vol.314 , pp. 1-16
    • Maury, E.1    Brichard, S.M.2
  • 26
    • 77954348590 scopus 로고    scopus 로고
    • Adipose tissue inflammation: Novel insight into the role of macrophages and lymphocytes
    • Sell H, Eckel J: Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes. Curr Opin Clin Nutr Metab Care 2010; 13: 366-370.
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 366-370
    • Sell, H.1    Eckel, J.2
  • 28
    • 80053303830 scopus 로고    scopus 로고
    • Autophagy and cytokines
    • Harris J:Autophagy and cytokines. Cytokine 2011; 56: 140-144.
    • (2011) Cytokine , vol.56 , pp. 140-144
    • Harris, J.1
  • 29
    • 66349121718 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
    • Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssegur J, Mazure NM: Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 2009; 29: 2570-2581.
    • (2009) Mol Cell Biol , vol.29 , pp. 2570-2581
    • Bellot, G.1    Garcia-Medina, R.2    Gounon, P.3    Chiche, J.4    Roux, D.5    Pouyssegur, J.6    Mazure, N.M.7
  • 31
    • 62949091373 scopus 로고    scopus 로고
    • Autophagy: A lysosomal degradation pathway with a central role in health and disease
    • Eskelinen EL, Saftig P: Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 2009; 1793: 664-673.
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 664-673
    • Eskelinen, E.L.1    Saftig, P.2
  • 32
    • 77954230819 scopus 로고    scopus 로고
    • Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress
    • Wang Y, Singh R, Xiang Y, Czaja MJ: Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress. Hepatology 2010; 52: 266-277.
    • (2010) Hepatology , vol.52 , pp. 266-277
    • Wang, Y.1    Singh, R.2    Xiang, Y.3    Czaja, M.J.4
  • 33
    • 84863083811 scopus 로고    scopus 로고
    • Circadian autophagy rhythm: A link between clock and metabolism?
    • Ma D, Li S, Molusky MM, Lin JD: Circadian autophagy rhythm: a link between clock and metabolism? Trends Endocrinol Metab 2012; 23: 319-325.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 319-325
    • Ma, D.1    Li, S.2    Molusky, M.M.3    Lin, J.D.4
  • 34
    • 48249140220 scopus 로고    scopus 로고
    • Diurnal rhythms of autophagy: Implications for cell biology and human disease
    • Sachdeva UM, Thompson CB: Diurnal rhythms of autophagy: implications for cell biology and human disease. Autophagy 2008; 4: 581-589.
    • (2008) Autophagy , vol.4 , pp. 581-589
    • Sachdeva, U.M.1    Thompson, C.B.2
  • 36
    • 76149141225 scopus 로고    scopus 로고
    • Metabolism and circadian rhythms-implications for obesity
    • Froy O: Metabolism and circadian rhythms-implications for obesity. Endocr Rev 2010; 31: 1-24.
    • (2010) Endocr Rev , vol.31 , pp. 1-24
    • Froy, O.1
  • 39
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • Yang L, Li P, Fu S, Calay ES, Hotamisligil GS: Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010; 11: 467-478.
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 41
    • 84868145847 scopus 로고    scopus 로고
    • The 'Janus-faced role' of autophagy in neuronal sickness: Focus on neurodegeneration
    • Viscomi MT, D'Amelio M: The 'Janus-faced role' of autophagy in neuronal sickness: focus on neurodegeneration. Mol Neurobiol 2012; 46: 513-521.
    • (2012) Mol Neurobiol , vol.46 , pp. 513-521
    • Viscomi, M.T.1    D'Amelio, M.2
  • 42
    • 69549134165 scopus 로고    scopus 로고
    • Autophagy-mediated insulin receptor downregulation contributes to endoplasmic reticulum stress-induced insulin resistance
    • Zhou L, Zhang J, Fang Q, Liu M, Liu X, Jia W, Dong LQ, Liu F: Autophagy-mediated insulin receptor downregulation contributes to endoplasmic reticulum stress-induced insulin resistance. Mol Pharmacol 2009; 76: 596-603.
    • (2009) Mol Pharmacol , vol.76 , pp. 596-603
    • Zhou, L.1    Zhang, J.2    Fang, Q.3    Liu, M.4    Liu, X.5    Jia, W.6    Dong, L.Q.7    Liu, F.8
  • 44
    • 84856748733 scopus 로고    scopus 로고
    • Cell death by autophagy: Facts and apparent artefacts
    • Denton D, Nicolson S, Kumar S: Cell death by autophagy: facts and apparent artefacts. Cell Death Differ 2012; 19: 87-95.
    • (2012) Cell Death Differ , vol.19 , pp. 87-95
    • Denton, D.1    Nicolson, S.2    Kumar, S.3
  • 48
    • 71749088821 scopus 로고    scopus 로고
    • CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization
    • Roca H, Varsos ZS, Sud S, Craig MJ, Ying C, Pienta KJ: CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization. J Biol Chem 2009; 284: 34342-34354.
    • (2009) J Biol Chem , vol.284 , pp. 34342-34354
    • Roca, H.1    Varsos, Z.S.2    Sud, S.3    Craig, M.J.4    Ying, C.5    Pienta, K.J.6
  • 49
    • 82455210868 scopus 로고    scopus 로고
    • Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta
    • Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V: Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. The EMBO J 2011; 30: 4701-4711.
    • (2011) The EMBO J , vol.30 , pp. 4701-4711
    • Dupont, N.1    Jiang, S.2    Pilli, M.3    Ornatowski, W.4    Bhattacharya, D.5    Deretic, V.6
  • 50
    • 78649262849 scopus 로고    scopus 로고
    • Autophagy: Roles in obesity-induced ER stress and adiponectin downregulation in adipocytes
    • Zhou L, Liu F: Autophagy: roles in obesity-induced ER stress and adiponectin downregulation in adipocytes. Autophagy 2010; 6: 1196-1197.
    • (2010) Autophagy , vol.6 , pp. 1196-1197
    • Zhou, L.1    Liu, F.2
  • 51
    • 78049263472 scopus 로고    scopus 로고
    • DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation
    • Zhou L, Liu M, Zhang J, Chen H, Dong LQ, Liu F: DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation. Diabetes 2010; 59: 2809-2816.
    • (2010) Diabetes , vol.59 , pp. 2809-2816
    • Zhou, L.1    Liu, M.2    Zhang, J.3    Chen, H.4    Dong, L.Q.5    Liu, F.6
  • 52
    • 84862138701 scopus 로고    scopus 로고
    • Adiponectin in cardiovascular inflammation and obesity
    • Aprahamian TR, Sam F: Adiponectin in cardiovascular inflammation and obesity. Int J Inflam 2011; 2011: 376909.
    • (2011) Int J Inflam , vol.2011 , pp. 376909
    • Aprahamian, T.R.1    Sam, F.2
  • 54
    • 84872845688 scopus 로고    scopus 로고
    • The autophagic inhibitor 3-methyladenine [3-MA] potently stimulates PKA-dependent lipolysis in adipocytes
    • doi: 10. 1111/j147653812012 02110 x
    • Heckmann BL, Yang X, Zhang X, Liu J: The autophagic inhibitor 3-methyladenine [3-MA] potently stimulates PKA-dependent lipolysis in adipocytes. Br J Pharmacol 2012; doi: 10. 1111/j. 1476-5381. 2012. 02110. x.
    • (2012) Br J Pharmacol
    • Heckmann, B.L.1    Yang, X.2    Zhang, X.3    Liu, J.4
  • 55
    • 65549166714 scopus 로고    scopus 로고
    • Lipophagy: Selective catabolism designed for lipids
    • Weidberg H, Shvets E, Elazar Z: Lipophagy: selective catabolism designed for lipids. Dev Cell 2009; 16: 628-630.
    • (2009) Dev Cell , vol.16 , pp. 628-630
    • Weidberg, H.1    Shvets, E.2    Elazar, Z.3
  • 56
    • 79958030075 scopus 로고    scopus 로고
    • Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase
    • Ouimet M, Franklin V, Mak E, Liao X, Tabas I, Marcel YL: Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. Cell Metab 2011; 13: 655-667.
    • (2011) Cell Metab , vol.13 , pp. 655-667
    • Ouimet, M.1    Franklin, V.2    Mak, E.3    Liao, X.4    Tabas, I.5    Marcel, Y.L.6
  • 57
    • 84857653989 scopus 로고    scopus 로고
    • Regulation of lipid droplet cholesterol efflux from macrophage foam cells
    • Ouimet M, Marcel YL: Regulation of lipid droplet cholesterol efflux from macrophage foam cells. Arterioscler Thromb Vasc Biol 2012; 32: 575-581.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 575-581
    • Ouimet, M.1    Marcel, Y.L.2
  • 58
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White E: Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer 2012; 12: 401-410.
    • (2012) Nat Rev Cancer , vol.12 , pp. 401-410
    • White, E.1
  • 59
    • 33645115547 scopus 로고    scopus 로고
    • Adding chloroquine to conventional treatment for glioblastoma multiforme: A randomized, double-blind, placebo-controlled trial
    • Sotelo J, Briceno E, Lopez-Gonzalez MA: Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 2006; 144: 337-343. (Pubitemid 46768188)
    • (2006) Annals of Internal Medicine , vol.144 , Issue.5 , pp. 337-343
    • Sotelo, J.1    Briceno, E.2    Lopez-Gonzalez, M.A.3
  • 61
    • 69949106925 scopus 로고    scopus 로고
    • The double-edged sword of autophagy modulation in cancer
    • White E, DiPaola RS: The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 2009; 15: 5308-5316.
    • (2009) Clin Cancer Res , vol.15 , pp. 5308-5316
    • White, E.1    Dipaola, R.S.2
  • 62
    • 81755178342 scopus 로고    scopus 로고
    • Autophagy in atherosclerosis: A potential drug target for plaque stabilization
    • Schrijvers DM, De Meyer GR, Martinet W: Autophagy in atherosclerosis: a potential drug target for plaque stabilization. Arterioscler Thromb Vasc Biol 2011; 31: 2787-2791.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2787-2791
    • Schrijvers, D.M.1    De Meyer, G.R.2    Martinet, W.3
  • 63
    • 84859896427 scopus 로고    scopus 로고
    • Contribution of impaired mitochondrial autophagy to cardiac aging: Mechanisms and therapeutic opportunities
    • Dutta D, Calvani R, Bernabei R, Leeuwenburgh C, Marzett, E: Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities. Circ Res 2012; 110: 1125-1138.
    • (2012) Circ Res , vol.110 , pp. 1125-1138
    • Dutta, D.1    Calvani, R.2    Bernabei, R.3    Leeuwenburgh, C.4    Marzett, E.5
  • 64
    • 84857058225 scopus 로고    scopus 로고
    • Control of autophagy as a therapy for neurodegenerative disease
    • Harris H, Rubinsztein DC: Control of autophagy as a therapy for neurodegenerative disease. Nat Rev Neurol 2012, 8, :108-117.
    • (2012) Nat Rev Neurol , vol.8 , pp. 108-117
    • Harris, H.1    Rubinsztein, D.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.