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Volumn 31, Issue 12, 2011, Pages 2787-2791

Autophagy in atherosclerosis: A potential drug target for plaque stabilization

Author keywords

atherosclerosis; autophagy; cell death; pharmacology; plaque stabilization

Indexed keywords

GREEN FLUORESCENT PROTEIN;

EID: 81755178342     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.224899     Document Type: Article
Times cited : (164)

References (53)
  • 1
    • 0347626252 scopus 로고    scopus 로고
    • Autophagy: A regulated bulk degradation process inside cells
    • DOI 10.1016/j.bbrc.2003.07.023
    • Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun. 2004;313:453-458. (Pubitemid 37543608)
    • (2004) Biochemical and Biophysical Research Communications , vol.313 , Issue.2 , pp. 453-458
    • Yoshimori, T.1
  • 2
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • DOI 10.1126/science.1099993
    • Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science. 2004;306:990-995. (Pubitemid 39482894)
    • (2004) Science , vol.306 , Issue.5698 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 4
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: Core molecular machinery and signaling regulation
    • Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol. 2010;22:124-131.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 5
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 6
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • DOI 10.1038/nature06639, PII NATURE06639
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature. 2008;45:1069-1075. (Pubitemid 351317450)
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 7
    • 61949233502 scopus 로고    scopus 로고
    • Autophagy in atherosclerosis: A cell survival and death phenomenon with therapeutic potential
    • Martinet W, De Meyer GRY. Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential. Circ Res. 2009;104:304-317.
    • (2009) Circ Res , vol.104 , pp. 304-317
    • Martinet, W.1    De Meyer Gry2
  • 8
  • 10
    • 33646840681 scopus 로고    scopus 로고
    • Autophagy: A protective mechanism in response to stress and inflammation
    • Heymann D. Autophagy: a protective mechanism in response to stress and inflammation. Curr Opin Investig Drugs. 2006;7:443-450. (Pubitemid 43772984)
    • (2006) Current Opinion in Investigational Drugs , vol.7 , Issue.5 , pp. 443-450
    • Heymann, D.1
  • 11
    • 33747863220 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and TNF-α regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
    • DOI 10.1111/j.1440-1711.2006.01454.x
    • Jia G, Cheng G, Gangahar DM, Agrawal DK. Insulin-like growth factor-1 and TNF-αregulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells. Immunol Cell Biol. 2006;84:448-454. (Pubitemid 44286038)
    • (2006) Immunology and Cell Biology , vol.84 , Issue.5 , pp. 448-454
    • Jia, G.1    Cheng, G.2    Gangahar, D.M.3    Agrawal, D.K.4
  • 12
    • 78650890352 scopus 로고    scopus 로고
    • Regulation of autophagy by ROS: Physiology and pathology
    • Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci. 2011;36:30-38.
    • (2011) Trends Biochem Sci , vol.36 , pp. 30-38
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 13
    • 79955697957 scopus 로고    scopus 로고
    • Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: Prevention by HDLs
    • Muller M, Salvayre R, Negre-Salvayre A, Vindis C. Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs. Autophagy. 2011;7:541-543.
    • (2011) Autophagy , vol.7 , pp. 541-543
    • Muller, M.1    Salvayre, R.2    Negre-Salvayre, A.3    Vindis, C.4
  • 14
    • 34548604527 scopus 로고    scopus 로고
    • No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy
    • DOI 10.1016/j.ejcb.2007.06.006, PII S0171933507000933
    • Nowicki M, Zabirnyk O, Duerrschmidt N, Borlak J, Spanel-Borowski K. No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy. Eur J Cell Biol. 2007;86:605-616. (Pubitemid 47408713)
    • (2007) European Journal of Cell Biology , vol.86 , Issue.10 , pp. 605-616
    • Nowicki, M.1    Zabirnyk, O.2    Duerrschmidt, N.3    Borlak, J.4    Spanel-Borowski, K.5
  • 15
    • 77953506788 scopus 로고    scopus 로고
    • ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
    • Qin L, Wang Z, Tao L, Wang Y. ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy. 2010;6: 239-247.
    • (2010) Autophagy , vol.6 , pp. 239-247
    • Qin, L.1    Wang, Z.2    Tao, L.3    Wang, Y.4
  • 16
    • 38949119423 scopus 로고    scopus 로고
    • Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3
    • Azad MB, Chen Y, Henson ES, Cizeau J, Millan-Ward E, Israels SJ, Gibson SB. Hypoxia induces autophagic cell death in apoptosis competent cells through a mechanism involving BNIP3. Autophagy. 2008;4: 195-204. (Pubitemid 351231183)
    • (2008) Autophagy , vol.4 , Issue.2 , pp. 195-204
    • Azad, M.B.1    Chen, Y.2    Henson, E.S.3    Cizeau, J.4    McMillan-Ward, E.5    Israels, S.J.6    Gibson, S.B.7
  • 18
    • 1542283812 scopus 로고    scopus 로고
    • In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
    • DOI 10.1091/mbc.E03-09-0704
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell. 2004;15:1101-1111. (Pubitemid 38316219)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.3 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 19
    • 10644244534 scopus 로고    scopus 로고
    • 7-Ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells
    • DOI 10.1161/01.ATV.0000146266.65820.a1
    • Martinet W, De Bie M, Schrijvers DM, De Meyer GRY, Herman AG, Kockx MM. 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:2296-2301. (Pubitemid 39658032)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.12 , pp. 2296-2301
    • Martinet, W.1    De Bie, M.2    Schrijvers, D.M.3    De Meyer, G.R.Y.4    Herman, A.G.5    Kockx, M.M.6
  • 22
    • 77951915586 scopus 로고    scopus 로고
    • Autophagy during cardiac stress: Joys and frustrations of autophagy
    • Gottlieb RA, Mentzer RM. Autophagy during cardiac stress: joys and frustrations of autophagy. Annu Rev Physiol. 2010;72:45-59.
    • (2010) Annu Rev Physiol , vol.72 , pp. 45-59
    • Gottlieb, R.A.1    Mentzer, R.M.2
  • 23
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura S, Noda T, Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy. 2007;3:452-460. (Pubitemid 47293726)
    • (2007) Autophagy , vol.3 , Issue.5 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 24
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140:313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 26
    • 47249152694 scopus 로고    scopus 로고
    • Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells
    • DOI 10.1038/bjp.2008.181, PII BJP2008181
    • Martinet W, Schrijvers DM, Timmermans JP, Bult H. Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells. Br J Pharmacol. 2008;154:1236-1246. (Pubitemid 351992056)
    • (2008) British Journal of Pharmacology , vol.154 , Issue.6 , pp. 1236-1246
    • Martinet, W.1    Schrijvers, D.M.2    Timmermans, J.-P.3    Bult, H.4
  • 27
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • DOI 10.1038/sj.onc.1207521
    • Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004;23:2891-2906. (Pubitemid 38638851)
    • (2004) Oncogene , vol.23 , Issue.16 REV. ISSUE 2 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 28
    • 41149116150 scopus 로고    scopus 로고
    • Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells
    • DOI 10.1042/BJ20071063
    • Hill BG, Haberzettl P, Ahmed Y, Srivastava S, Bhatnagar A. Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells. Biochem J. 2008;410:525-534. (Pubitemid 351429023)
    • (2008) Biochemical Journal , vol.410 , Issue.3 , pp. 525-534
    • Hill, B.G.1    Haberzettl, P.2    Ahmed, Y.3    Srivastava, S.4    Bhatnagar, A.5
  • 29
    • 77956813124 scopus 로고    scopus 로고
    • Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells
    • Xu K, Yang Y, Yan M, Zhan J, Fu X, Zheng X. Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells. J Lipid Res. 2010;51:2581-2590.
    • (2010) J Lipid Res , vol.51 , pp. 2581-2590
    • Xu, K.1    Yang, Y.2    Yan, M.3    Zhan, J.4    Fu, X.5    Zheng, X.6
  • 31
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • DOI 10.1172/JCI26390
    • Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest. 2005;115:2679-2688. (Pubitemid 41434392)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 32
    • 33846816952 scopus 로고    scopus 로고
    • Selective Depletion of Macrophages in Atherosclerotic Plaques via Macrophage-Specific Initiation of Cell Death
    • DOI 10.1016/j.tcm.2006.12.004, PII S1050173807000059
    • Martinet W, Verheye S, De Meyer GRY. Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death. Trends Cardiovasc Med. 2007;17:69-75. (Pubitemid 46205331)
    • (2007) Trends in Cardiovascular Medicine , vol.17 , Issue.2 , pp. 69-75
    • Martinet, W.1    Verheye, S.2    De Meyer, G.R.Y.3
  • 33
    • 79952321917 scopus 로고    scopus 로고
    • Phagocytosis of cell dying through autophagy induces inflammasome activation and IL-1 release in human macrophages
    • Petrovsky G, Ayna G, Majai G, Hodrea J, Benko S, Madi A, Fesus L. Phagocytosis of cell dying through autophagy induces inflammasome activation and IL-1 release in human macrophages. Autophagy. 2011; 7:321-330.
    • (2011) Autophagy , vol.7 , pp. 321-330
    • Petrovsky, G.1    Ayna, G.2    Majai, G.3    Hodrea, J.4    Benko, S.5    Madi, A.6    Fesus, L.7
  • 34
    • 34249815482 scopus 로고    scopus 로고
    • Autophagy, ageing and apoptosis: The role of oxidative stress and lysosomal iron
    • DOI 10.1016/j.abb.2007.01.013, PII S000398610700029X, Highlight Issue: Pro- and antiapoptotic Signalling
    • Kurz T, Terman A, Brunk UT. Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron. Arch Biochem Biophys. 2007;462: 220-230. (Pubitemid 46856317)
    • (2007) Archives of Biochemistry and Biophysics , vol.462 , Issue.2 , pp. 220-230
    • Kurz, T.1    Terman, A.2    Brunk, U.T.3
  • 36
    • 77957656800 scopus 로고    scopus 로고
    • Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)
    • Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC. Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4). Autophagy. 2010;6:936-947.
    • (2010) Autophagy , vol.6 , pp. 936-947
    • Shu, C.W.1    Drag, M.2    Bekes, M.3    Zhai, D.4    Salvesen, G.S.5    Reed, J.C.6
  • 38
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy gene-dependent clearance of apoptotic cells during embryonic development
    • DOI 10.1016/j.cell.2006.12.044, PII S009286740700178X
    • Qu X, Zou Z, Sun Q, Luby-Phelps K, Cheng P, Hogan RN, Gilpin C, Levine B. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell. 2007;128:931-946. (Pubitemid 46341412)
    • (2007) Cell , vol.128 , Issue.5 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.N.6    Gilpin, C.7    Levine, B.8
  • 40
    • 52449109523 scopus 로고    scopus 로고
    • Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/-mice
    • Thorp E, Cui D, Schrijvers DM, Kuriakose G, Tabas I. Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-/-mice. Arterioscler Thromb Vasc Biol. 2008;28:1421-1428.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1421-1428
    • Thorp, E.1    Cui, D.2    Schrijvers, D.M.3    Kuriakose, G.4    Tabas, I.5
  • 42
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and selfkilling: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol. 2007;8:741-752. (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 45
    • 53549132786 scopus 로고    scopus 로고
    • Beclin-1 bridges autophagy, apoptosis and differentiation
    • Wang J. Beclin-1 bridges autophagy, apoptosis and differentiation. Autophagy. 2008;4:947-948.
    • (2008) Autophagy , vol.4 , pp. 947-948
    • Wang, J.1
  • 47
    • 34547186029 scopus 로고    scopus 로고
    • Apoptosis regulation by autophagy gene 5
    • DOI 10.1016/j.critrevonc.2007.06.005, PII S104084280700114X
    • Yousefi S, Simon HU. Apoptosis regulation by autophagy gene 5. Crit Rev Oncol Hematol. 2007;63:241-244. (Pubitemid 47126867)
    • (2007) Critical Reviews in Oncology/Hematology , vol.63 , Issue.3 , pp. 241-244
    • Yousefi, S.1    Simon, H.-U.2
  • 50
    • 41249099242 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase1 induces autophagy
    • Oh M, Choi IK, Kwon HJ. Inhibition of histone deacetylase1 induces autophagy. Biochem Biophys Res Commun. 2008;369:1179-1183.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 1179-1183
    • Oh, M.1    Choi, I.K.2    Kwon, H.J.3
  • 51
    • 78650836614 scopus 로고    scopus 로고
    • Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors
    • Yang PM, Chen C-C. Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors. Autophagy. 2011;7: 107-108.
    • (2011) Autophagy , vol.7 , pp. 107-108
    • Yang, P.M.1    Chen, C.-C.2
  • 53
    • 79957484652 scopus 로고    scopus 로고
    • Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis
    • Zhou B, Margariti A, Zeng L, Xu Q. Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis. Cardiovasc Res. 2011;90: 413-420.
    • (2011) Cardiovasc Res , vol.90 , pp. 413-420
    • Zhou, B.1    Margariti, A.2    Zeng, L.3    Xu, Q.4


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