Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet

Molecular Genetics and Metabolism

Volumn 107, Issue 3, 2012, Pages 416-427

  Devarajan, Asokan ^a   Grijalva, Victor R ^a   Bourquard, Noam ^a   Meriwether, David ^b   Imaizumi, Satoshi ^a   Shin, Bo Chul ^b   Devaskar, Sherin U ^b   Reddy, Srinivasa T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endoplasmic reticulum; Macrophages; Mitochondria; Oxidative stress; Paraoxonase 2

Indexed keywords

APOLIPOPROTEIN E; ARYLDIALKYLPHOSPHATASE 2; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; RU 360; UNCLASSIFIED DRUG; XESTOSPONGIN C;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL STRESS; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM STRESS; ENZYME DEFICIENCY; FEMALE; MACROPHAGE; MOUSE; NONHUMAN; PARAOXONASE 2 DEFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; AORTA; APOLIPOPROTEINS E; APOPTOSIS; ARYLDIALKYLPHOSPHATASE; ATHEROSCLEROSIS; CALCIUM; CALCIUM SIGNALING; CELL NUCLEUS; CELL SURVIVAL; DIET; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HOMEOSTASIS; MACROCYCLIC COMPOUNDS; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOCHONDRIA; OXAZOLES; OXIDATIVE STRESS; RUTHENIUM COMPOUNDS;

MUS;

EID: 84867895307     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.06.020     Document Type: Article

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