PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death

Cell Death and Differentiation

Volumn 19, Issue 9, 2012, Pages 1549-1560

  Schweikert, E M ^a   Devarajan, A ^b   Witte, I ^a   Wilgenbus, P ^a   Amort, J ^a   Forstermann U ^a   Shabazian, A ^b   Grijalva, V ^b   Shih, D M ^b   Farias Eisner, R ^b   Teiber, J F ^c   Reddy, S T ^b,d   Horke, S ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

apoptosis; cancer; endoplasmic reticulum stress; mitochondria; oxidative stress; paraoxonase

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ARYLDIALKYLPHOSPHATASE 3; MITOGEN ACTIVATED PROTEIN KINASE; SEMIQUINONE; SUPEROXIDE; UBIDECARENONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER TISSUE; CELL CULTURE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; ARYLDIALKYLPHOSPHATASE; CYTOCHROMES C; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MITOCHONDRIA; NEOPLASM PROTEINS; NEOPLASMS; SUPEROXIDES; UP-REGULATION;

MUS;

EID: 84865185479     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.35     Document Type: Article

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