-
1
-
-
0029937118
-
The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family
-
Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics 1996; 33:498-507.
-
(1996)
Genomics
, vol.33
, pp. 498-507
-
-
Primo-Parmo, S.L.1
Sorenson, R.C.2
Teiber, J.3
La Du, B.N.4
-
2
-
-
0035976903
-
Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein
-
Ng CJ, Wadleigh DJ, Gangopadhyay A, et al. Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein. J Biol Chem 2001; 276:44444-44449.
-
(2001)
J Biol Chem
, vol.276
, pp. 44444-44449
-
-
Ng, C.J.1
Wadleigh, D.J.2
Gangopadhyay, A.3
-
3
-
-
10644244414
-
The paraoxonase gene family and atherosclerosis
-
Ng CJ, Shih DM, Hama SY, et al. The paraoxonase gene family and atherosclerosis. Free Radic Biol Med 2005; 38:153-163.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 153-163
-
-
Ng, C.J.1
Shih, D.M.2
Hama, S.Y.3
-
4
-
-
0035865671
-
Hydrolysis of platelet-activating factor by human serum paraoxonase
-
Rodrigo LB, Mackness PN, Durrington A, et al. Hydrolysis of platelet-activating factor by human serum paraoxonase. Biochem J 2001; 354:1-7.
-
(2001)
Biochem J
, vol.354
, pp. 1-7
-
-
Rodrigo, L.B.1
Mackness, P.N.2
Durrington, A.3
-
5
-
-
0037339957
-
Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress
-
Rosenblat M, Draganov D, Watson CE, et al. Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress. Arterioscler Thromb Vasc Biol 2003; 23:468-474.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 468-474
-
-
Rosenblat, M.1
Draganov, D.2
Watson, C.E.3
-
6
-
-
34247213490
-
Paraoxonase 2 reduced oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation
-
This study describes the potential role of PON2 in reducing oxidative stress and vascular inflammation
-
Horke S, Writte I, Wilegenbus P, et al. Paraoxonase 2 reduced oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation. Circulation 2007; 115:2055-2064. This study describes the potential role of PON2 in reducing oxidative stress and vascular inflammation.
-
(2007)
Circulation
, vol.115
, pp. 2055-2064
-
-
Horke, S.1
Writte, I.2
Wilegenbus, P.3
-
7
-
-
66749175476
-
-
Bourquard N, Shih DM, Ng CJ, et al. Paraoxonases and their role in disease development and xenobiotic metabolism. In: Mackness et al., editors. Proteins and cell regulation. 6. New York: Springer; 2007. pp. 103-128. The role of PON2 and PON3 in atherosclerosis and related traits. This is an exhaustive review of all three PON genes.
-
Bourquard N, Shih DM, Ng CJ, et al. Paraoxonases and their role in disease development and xenobiotic metabolism. In: Mackness et al., editors. Proteins and cell regulation. vol. 6. New York: Springer; 2007. pp. 103-128. The role of PON2 and PON3 in atherosclerosis and related traits. This is an exhaustive review of all three PON genes.
-
-
-
-
8
-
-
0347753275
-
Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: Contributions to atherosclerosis
-
Cathcart MK. Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis. Arterioscler Thromb Vasc Biol 2004; 24:23-28.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 23-28
-
-
Cathcart, M.K.1
-
9
-
-
8544227651
-
Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation intomacrophages
-
Shiner M, Fuhrman B, Aviram M. Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation intomacrophages. Free Radic Biol Med 2004; 37:2052-2063.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 2052-2063
-
-
Shiner, M.1
Fuhrman, B.2
Aviram, M.3
-
10
-
-
33749544927
-
Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-b containing lipoproteins - antiatherogenic role for paraoxonase-2
-
Ng CJ, Villa N, Hama SY, et al. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-b containing lipoproteins - antiatherogenic role for paraoxonase-2. J Biol Chem 2006; 281:29491-29500.
-
(2006)
J Biol Chem
, vol.281
, pp. 29491-29500
-
-
Ng, C.J.1
Villa, N.2
Hama, S.Y.3
-
11
-
-
0035958917
-
The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways
-
Fisher EA, Pan M, Chen X, et al. The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways. J Biol Chem 2001; 276:27855-27863.
-
(2001)
J Biol Chem
, vol.276
, pp. 27855-27863
-
-
Fisher, E.A.1
Pan, M.2
Chen, X.3
-
12
-
-
33751093349
-
Paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein-E deficient mice
-
Ng CJ, Hama SY, Navab M, et al. Paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein-E deficient mice. Mol Genet Metab 2006; 89:368-373.
-
(2006)
Mol Genet Metab
, vol.89
, pp. 368-373
-
-
Ng, C.J.1
Hama, S.Y.2
Navab, M.3
-
13
-
-
0034721761
-
Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein- associated lactonase and protects low density lipoprotein against oxidation
-
Draganov DI, Stetson PL, Watson CE, et al. Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein- associated lactonase and protects low density lipoprotein against oxidation. J Biol Chem 2000; 275:33435-33442.
-
(2000)
J Biol Chem
, vol.275
, pp. 33435-33442
-
-
Draganov, D.I.1
Stetson, P.L.2
Watson, C.E.3
-
14
-
-
0035048507
-
Human paraoxonase-3 is an HDL- associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids
-
Reddy ST, Wadleigh DJ, Grijalva V, et al. Human paraoxonase-3 is an HDL- associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol 2001; 21:542-547.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 542-547
-
-
Reddy, S.T.1
Wadleigh, D.J.2
Grijalva, V.3
-
15
-
-
34249305527
-
Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice
-
This study shows that transient expression of PON3 is sufficient to reduce atherosclerosis in advanced atherosclerotic lesions in apoE null mice
-
Ng CJ, Bourquard N, Villa N, et al. Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2007; 27:1368-1374. This study shows that transient expression of PON3 is sufficient to reduce atherosclerosis in advanced atherosclerotic lesions in apoE null mice.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1368-1374
-
-
Ng, C.J.1
Bourquard, N.2
Villa, N.3
-
16
-
-
34247590214
-
Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice
-
This paper not only demonstrates the athero-protective nature of PON3 in transgenic mouse models but also shows that PON3 may be an important player in obesity as well
-
Shih DM, Xia Yr, Wang XP, et al. Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Cir Res 2007; 100:1200-1207. This paper not only demonstrates the athero-protective nature of PON3 in transgenic mouse models but also shows that PON3 may be an important player in obesity as well.
-
(2007)
Cir Res
, vol.100
, pp. 1200-1207
-
-
Shih, D.M.1
Xia, Y.2
Wang, X.P.3
|