Emerging real-time technologies in molecular medicine and the evolution of integrated 'pharmacomics' approaches to personalized medicine and drug discovery

Pharmacology and Therapeutics

Volumn 136, Issue 3, 2012, Pages 295-304

  Milward, Elizabeth A ^a   Daneshi, Nilofar ^a   Johnstone, Daniel M ^a,b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Drug discovery; Microarray; Next generation sequencing; Pharmacomics; Real time sequencing; Transcriptomics

Indexed keywords

BEDAQUILINE; COMPLEMENTARY DNA; IMATINIB; NILOTINIB; PROTEOME; TRANSCRIPTOME;

CHRONIC MYELOID LEUKEMIA; DNA MICROARRAY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG MECHANISM; DRUG METABOLISM; DRUG RESEARCH; DRUG RESPONSE; GENE AMPLIFICATION; GENE SEQUENCE; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE MAP; HIGH THROUGHPUT SEQUENCING; HUMAN; PERSONALIZED MEDICINE; PHARMACOGENOMICS; POINT OF CARE TESTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEOMICS; REVIEW; RNA SEQUENCE; RNA TRANSCRIPTION; SEQUENCE ANALYSIS; SINGE MOLECULE REAL TIME SEQUENCING; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTOMICS;

ANIMALS; DRUG DISCOVERY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INDIVIDUALIZED MEDICINE; MOLECULAR MEDICINE; PROTEOMICS; TRANSCRIPTOME;

EID: 84867887849     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.08.008     Document Type: Review

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