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Volumn 4, Issue 6, 2009, Pages

Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR PHOSPHATE; ATAZANAVIR; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; LAMIVUDINE; LOPINAVIR; NELFINAVIR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; TENOFOVIR; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT; COMPLEMENTARY DNA; VIRUS RNA;

EID: 67650682133     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006079     Document Type: Article
Times cited : (114)

References (35)
  • 1
    • 1642277960 scopus 로고    scopus 로고
    • Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine
    • Dykes C, Najjar J, Bosch RJ, Wantman M, Furtado M, et al. (2004) Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine. J Infect Dis 189(6): 1091-1096.
    • (2004) J Infect Dis , vol.189 , Issue.6 , pp. 1091-1096
    • Dykes, C.1    Najjar, J.2    Bosch, R.J.3    Wantman, M.4    Furtado, M.5
  • 2
    • 2942676469 scopus 로고    scopus 로고
    • Sequencing-based detection of low-frequency human immunodeficiency virus type 1 drug-resistant mutants by an RNA/DNA heteroduplex generator-tracking assay
    • Kapoor A, Jones M, Shafer RW, Rhee SY, Kazanjian P, et al. (2004) Sequencing-based detection of low-frequency human immunodeficiency virus type 1 drug-resistant mutants by an RNA/DNA heteroduplex generator-tracking assay. J Virol 78(13): 7112-7123.
    • (2004) J Virol , vol.78 , Issue.13 , pp. 7112-7123
    • Kapoor, A.1    Jones, M.2    Shafer, R.W.3    Rhee, S.Y.4    Kazanjian, P.5
  • 3
    • 34548076341 scopus 로고    scopus 로고
    • Sensitive oligonucleotide ligation assay for low-level detection of nevirapine resistance mutations in human immunodeficiency virus type 1 quasispecies
    • Lalonde MS, Troyer RM, Syed AR, Bulime S, Demers K, et al. (2007) Sensitive oligonucleotide ligation assay for low-level detection of nevirapine resistance mutations in human immunodeficiency virus type 1 quasispecies. J Clin Microbiol 45(8): 2604-2615.
    • (2007) J Clin Microbiol , vol.45 , Issue.8 , pp. 2604-2615
    • Lalonde, M.S.1    Troyer, R.M.2    Syed, A.R.3    Bulime, S.4    Demers, K.5
  • 4
    • 11844257530 scopus 로고    scopus 로고
    • Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine
    • Lecossier D, Shulman NS, Morand-Joubert L, Shafer RW, Joly V, et al. (2005) Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. J Acquir Immune Defic Syndr 38(1): 37-42.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , Issue.1 , pp. 37-42
    • Lecossier, D.1    Shulman, N.S.2    Morand-Joubert, L.3    Shafer, R.W.4    Joly, V.5
  • 5
    • 10744223424 scopus 로고    scopus 로고
    • Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions
    • Metzner KJ, Bonhoeffer S, Fischer M, Karanicolas R, Allers K, et al. (2003) Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions. J Infect Dis 188(10): 1433-1443.
    • (2003) J Infect Dis , vol.188 , Issue.10 , pp. 1433-1443
    • Metzner, K.J.1    Bonhoeffer, S.2    Fischer, M.3    Karanicolas, R.4    Allers, K.5
  • 6
    • 27544452984 scopus 로고    scopus 로고
    • Detection of minor populations of drug-resistant HIV-1 in acute seroconverters
    • Metzner KJ, Rauch P, Walter H, Boesecke C, Zollner B, et al. (2005) Detection of minor populations of drug-resistant HIV-1 in acute seroconverters. AIDS 19(16): 1819-1825.
    • (2005) AIDS , vol.19 , Issue.16 , pp. 1819-1825
    • Metzner, K.J.1    Rauch, P.2    Walter, H.3    Boesecke, C.4    Zollner, B.5
  • 7
    • 33646481683 scopus 로고    scopus 로고
    • Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy
    • Palmer S, Boltz V, Maldarelli F, Kearney M, Halvas EK, et al. (2006) Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy. AIDS 20(5): 701-710.
    • (2006) AIDS , vol.20 , Issue.5 , pp. 701-710
    • Palmer, S.1    Boltz, V.2    Maldarelli, F.3    Kearney, M.4    Halvas, E.K.5
  • 8
    • 33646028218 scopus 로고    scopus 로고
    • Role of HIV-1 minority populations on resistance mutational pattern evolution and susceptibility to protease inhibitors
    • Roquebert B, Malet I, Wirden M, Tubiana R, Valantin MA, et al. (2006) Role of HIV-1 minority populations on resistance mutational pattern evolution and susceptibility to protease inhibitors. AIDS 20(2): 287-289.
    • (2006) AIDS , vol.20 , Issue.2 , pp. 287-289
    • Roquebert, B.1    Malet, I.2    Wirden, M.3    Tubiana, R.4    Valantin, M.A.5
  • 9
    • 34547643929 scopus 로고    scopus 로고
    • Characterization of mutation spectra with ultra-deep pyrosequencing: Application to HIV-1 drug resistance
    • Wang C, Mitsuya Y, Gharizadeh B, Ronaghi M, Shafer RW (2007) Characterization of mutation spectra with ultra-deep pyrosequencing: Application to HIV-1 drug resistance. Genome Res 17(8): 1195-1201.
    • (2007) Genome Res , vol.17 , Issue.8 , pp. 1195-1201
    • Wang, C.1    Mitsuya, Y.2    Gharizadeh, B.3    Ronaghi, M.4    Shafer, R.W.5
  • 10
    • 0042023525 scopus 로고    scopus 로고
    • Quality control trial for human immunodeficiency virus type 1 drug resistance testing using clinical samples reveals problems with detecting minority species and interpretation of test results
    • Korn K, Reil H, Walter H, Schmidt B (2003) Quality control trial for human immunodeficiency virus type 1 drug resistance testing using clinical samples reveals problems with detecting minority species and interpretation of test results. J Clin Microbiol 41(8): 3559-3565.
    • (2003) J Clin Microbiol , vol.41 , Issue.8 , pp. 3559-3565
    • Korn, K.1    Reil, H.2    Walter, H.3    Schmidt, B.4
  • 11
    • 0036210739 scopus 로고    scopus 로고
    • Underestimation of HIV type 1 drug resistance mutations: Results from the ENVA-2 genotyping proficiency program
    • Schuurman R, Brambilla D, de Groot T, Huang D, Land S, et al. (2002) Underestimation of HIV type 1 drug resistance mutations: Results from the ENVA-2 genotyping proficiency program. AIDS Res Hum Retroviruses 18(4): 243-248.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , Issue.4 , pp. 243-248
    • Schuurman, R.1    Brambilla, D.2    de Groot, T.3    Huang, D.4    Land, S.5
  • 12
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin JM (1995) HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267(5197): 483-489.
    • (1995) Science , vol.267 , Issue.5197 , pp. 483-489
    • Coffin, J.M.1
  • 13
    • 20844437104 scopus 로고    scopus 로고
    • Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012
    • Flys T, Nissley DV, Claasen CW, Jones D, Shi C, et al. (2005) Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012. J Infect Dis 192(1): 24-29.
    • (2005) J Infect Dis , vol.192 , Issue.1 , pp. 24-29
    • Flys, T.1    Nissley, D.V.2    Claasen, C.W.3    Jones, D.4    Shi, C.5
  • 14
    • 48849106876 scopus 로고    scopus 로고
    • Presence of minor populations of Y181C mutants detected by allele-specific PCR and risk of efavirenz failure in treatment-naive patients: Results of an ACTG5095 case-cohort study
    • Boston Feb 3-6: Abstract 83
    • Paredes R, Lalama C, Ribaudo HJea (2008) Presence of minor populations of Y181C mutants detected by allele-specific PCR and risk of efavirenz failure in treatment-naive patients: Results of an ACTG5095 case-cohort study. 15th Conference of Retroviruses and Opportunistic Infections. Boston Feb 3-6: Abstract 83.
    • (2008) 15th Conference of Retroviruses and Opportunistic Infections
    • Paredes, R.1    Lalama, C.2    HJea, R.3
  • 15
    • 48749086685 scopus 로고    scopus 로고
    • Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naive populations and associate with reduced treatment efficacy
    • Johnson JA, Li JF, Wei X, Lipscomb J, Irlbeck D, et al. (2008) Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naive populations and associate with reduced treatment efficacy. PLoS Med 5(7): e158.
    • (2008) PLoS Med , vol.5 , Issue.7
    • Johnson, J.A.1    Li, J.F.2    Wei, X.3    Lipscomb, J.4    Irlbeck, D.5
  • 16
    • 61849172898 scopus 로고    scopus 로고
    • Low-Abundance Drug-Resistant viral variants in chronically HIV-Infected, antiretroviral Treatment - Naive patients significantly impact treatment outcomes
    • Simen B, Simons J, Hullsiek K, Novak R, MacArthur R, et al. (2009) Low-Abundance Drug-Resistant viral variants in chronically HIV-Infected, antiretroviral Treatment - Naive patients significantly impact treatment outcomes. J Infect Dis 199(5): 693-701.
    • (2009) J Infect Dis , vol.199 , Issue.5 , pp. 693-701
    • Simen, B.1    Simons, J.2    Hullsiek, K.3    Novak, R.4    MacArthur, R.5
  • 17
    • 58749087348 scopus 로고    scopus 로고
    • Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients
    • Metzner KJ, Giulieri SG, Knoepfel SA, Rauch P, Burgisser P, et al. (2009) Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients. Clin Infect Dis 48(2): 239-247.
    • (2009) Clin Infect Dis , vol.48 , Issue.2 , pp. 239-247
    • Metzner, K.J.1    Giulieri, S.G.2    Knoepfel, S.A.3    Rauch, P.4    Burgisser, P.5
  • 18
    • 24044455869 scopus 로고    scopus 로고
    • Genome sequencing in microfabricated high-density picolitre reactors
    • Margulies M, Egholm M, Altman WE, Attiya S, Bader JS, et al. (2005) Genome sequencing in microfabricated high-density picolitre reactors. Nature 437(7057): 376-380.
    • (2005) Nature , vol.437 , Issue.7057 , pp. 376-380
    • Margulies, M.1    Egholm, M.2    Altman, W.E.3    Attiya, S.4    Bader, J.S.5
  • 20
    • 15844378825 scopus 로고    scopus 로고
    • Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays
    • Kozal MJ, Shah N, Shen N, Yang R, Fucini R, et al.(1996) Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nat Med 2(7): 753-759.
    • (1996) Nat Med , vol.2 , Issue.7 , pp. 753-759
    • Kozal, M.J.1    Shah, N.2    Shen, N.3    Yang, R.4    Fucini, R.5
  • 21
    • 33745223480 scopus 로고    scopus 로고
    • A population-based and longitudinal study of sexual behavior and multidrug-resistant HIV among patients in clinical care
    • Kozal MJ, Amico KR, Chiarella J, Cornman D, Fisher W, et al. (2006) A population-based and longitudinal study of sexual behavior and multidrug-resistant HIV among patients in clinical care. MedGenMed 8(2): 72.
    • (2006) MedGenMed , vol.8 , Issue.2 , pp. 72
    • Kozal, M.J.1    Amico, K.R.2    Chiarella, J.3    Cornman, D.4    Fisher, W.5
  • 22
    • 46349112103 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an international AIDS society-USA panel
    • Hirsch MS, Gunthard HF, Schapiro JM, Brun-Vezinet F, Clotet B, et al. (2008) Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an international AIDS society-USA panel. Clinical Infectious Diseases 47(2): 266-285.
    • (2008) Clinical Infectious Diseases , vol.47 , Issue.2 , pp. 266-285
    • Hirsch, M.S.1    Gunthard, H.F.2    Schapiro, J.M.3    Brun-Vezinet, F.4    Clotet, B.5
  • 23
    • 0037227021 scopus 로고    scopus 로고
    • Quantitative detection of low-copy-number mRNAs differing at single nucleotide positions
    • Stenman J, Lintula S, Rissanen O, Finne P, Hedstrom J, et al. (2003) Quantitative detection of low-copy-number mRNAs differing at single nucleotide positions. BioTechniques 34(1): 172-177.
    • (2003) BioTechniques , vol.34 , Issue.1 , pp. 172-177
    • Stenman, J.1    Lintula, S.2    Rissanen, O.3    Finne, P.4    Hedstrom, J.5
  • 24
    • 33745926178 scopus 로고    scopus 로고
    • Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing
    • Thomas RK, Nickerson E, Simons JF, Janne PA, Tengs T, et al. (2006) Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nat Med 12(7): 852-855.
    • (2006) Nat Med , vol.12 , Issue.7 , pp. 852-855
    • Thomas, R.K.1    Nickerson, E.2    Simons, J.F.3    Janne, P.A.4    Tengs, T.5
  • 25
    • 55249120981 scopus 로고    scopus 로고
    • Minority human immunodeficiency virus type 1 variants in antiretroviral-naive persons with reverse transcriptase codon 215 revertant mutations
    • Mitsuya Y, Varghese V, Wang C, Liu TF, Holmes SP, et al. (2008) Minority human immunodeficiency virus type 1 variants in antiretroviral-naive persons with reverse transcriptase codon 215 revertant mutations. J Virol 82(21): 10747-10755.
    • (2008) J Virol , vol.82 , Issue.21 , pp. 10747-10755
    • Mitsuya, Y.1    Varghese, V.2    Wang, C.3    Liu, T.F.4    Holmes, S.P.5
  • 26
    • 0034081772 scopus 로고    scopus 로고
    • Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine
    • Hanna GJ, Johnson VA, Kuritzkes DR, Richman DD, Brown AJ, et al. (2000) Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine. J Infect Dis 181(3): 904-911.
    • (2000) J Infect Dis , vol.181 , Issue.3 , pp. 904-911
    • Hanna, G.J.1    Johnson, V.A.2    Kuritzkes, D.R.3    Richman, D.D.4    Brown, A.J.5
  • 27
    • 0345306634 scopus 로고    scopus 로고
    • Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure
    • Marcelin AG, Delaugerre C, Wirden M, Viegas P, Simon A, et al. (2004) Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure. J Med Virol 72(1): 162-165.
    • (2004) J Med Virol , vol.72 , Issue.1 , pp. 162-165
    • Marcelin, A.G.1    Delaugerre, C.2    Wirden, M.3    Viegas, P.4    Simon, A.5
  • 28
    • 19944428265 scopus 로고    scopus 로고
    • Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis
    • Palmer S, Kearney M, Maldarelli F, Halvas EK, Bixby CJ, et al. (2005) Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis. J Clin Microbiol 43(1): 406-413.
    • (2005) J Clin Microbiol , vol.43 , Issue.1 , pp. 406-413
    • Palmer, S.1    Kearney, M.2    Maldarelli, F.3    Halvas, E.K.4    Bixby, C.J.5
  • 29
    • 0034867418 scopus 로고    scopus 로고
    • Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations
    • Devereux HL, Emery VC, Johnson MA, Loveday C (2001) Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations. J Med Virol 65(2): 218-224.
    • (2001) J Med Virol , vol.65 , Issue.2 , pp. 218-224
    • Devereux, H.L.1    Emery, V.C.2    Johnson, M.A.3    Loveday, C.4
  • 30
    • 59649126954 scopus 로고    scopus 로고
    • In vivo fitness cost of the M184V mutation in multidrug-resistant human immunodeficiency virus type 1 in the absence of lamivudine
    • Paredes R, Sagar M, Marconi VC, Hoh R, Martin JN, et al. (2009) In vivo fitness cost of the M184V mutation in multidrug-resistant human immunodeficiency virus type 1 in the absence of lamivudine. J Virol 83(4): 2038-2043.
    • (2009) J Virol , vol.83 , Issue.4 , pp. 2038-2043
    • Paredes, R.1    Sagar, M.2    Marconi, V.C.3    Hoh, R.4    Martin, J.N.5
  • 31
    • 0035923716 scopus 로고    scopus 로고
    • A fossil record of zidovudine resistance in transmitted isolates of HIV-1
    • Kuritzkes DR (2001) A fossil record of zidovudine resistance in transmitted isolates of HIV-1. Proc Natl Acad Sci U S A 98(24): 13485-13487.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 13485-13487
    • Kuritzkes, D.R.1
  • 32
    • 17044402473 scopus 로고    scopus 로고
    • HIV-1 drug resistance: Degree of underestimation by a cross-sectional versus a longitudinal testing approach
    • Harrigan PR, Wynhoven B, Brumme ZL, Brumme CJ, Sattha B, et al. (2005) HIV-1 drug resistance: Degree of underestimation by a cross-sectional versus a longitudinal testing approach. J Infect Dis 191(8): 1325-1330.
    • (2005) J Infect Dis , vol.191 , Issue.8 , pp. 1325-1330
    • Harrigan, P.R.1    Wynhoven, B.2    Brumme, Z.L.3    Brumme, C.J.4    Sattha, B.5
  • 33
    • 67650658279 scopus 로고    scopus 로고
    • Cross-sectional versus cumulative interpretation of HIV-1 drug resistance mutations
    • Yerly S, Michel PA, Emler S, et al. (2008) Cross-sectional versus cumulative interpretation of HIV-1 drug resistance mutations. Antivir Ther 13(3): A110.
    • (2008) Antivir Ther , vol.13 , Issue.3
    • Yerly, S.1    Michel, P.A.2    Emler, S.3
  • 34
    • 67650655101 scopus 로고    scopus 로고
    • Zaccarelli M, Lorenzini P, Tozzi Vea (2008) Are current or archived resistance mutations predictive of treatment failure in heavily pre-treated HIV patients? 6th European HIV Drug Resistance Workshop. March 26-28. Budapest. pp Abstract 42.
    • Zaccarelli M, Lorenzini P, Tozzi Vea (2008) Are current or archived resistance mutations predictive of treatment failure in heavily pre-treated HIV patients? 6th European HIV Drug Resistance Workshop. March 26-28. Budapest. pp Abstract 42.
  • 35
    • 0031020013 scopus 로고    scopus 로고
    • Comparison of QIAamp HCV kit spin columns, silica beads, and phenol-chloroform for recovering human immunodeficiency virus type 1 RNA from plasma
    • Shafer RW, Levee DJ, Winters MA, Richmond KL, Huang D, et al. (1997) Comparison of QIAamp HCV kit spin columns, silica beads, and phenol-chloroform for recovering human immunodeficiency virus type 1 RNA from plasma. J Clin Microbiol 35(2): 520-522.
    • (1997) J Clin Microbiol , vol.35 , Issue.2 , pp. 520-522
    • Shafer, R.W.1    Levee, D.J.2    Winters, M.A.3    Richmond, K.L.4    Huang, D.5


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