메뉴 건너뛰기




Volumn 17, Issue R2, 2008, Pages

Pharmacogenomics: Candidate gene identification, functional validation and mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION PROFILING; GENE TARGETING; GENETIC VARIABILITY; GENETICS; HUMAN; HUMAN GENOME; METHODOLOGY; PHARMACOGENETICS; REVIEW; STANDARD;

EID: 58149352685     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn270     Document Type: Article
Times cited : (54)

References (40)
  • 1
    • 0037421584 scopus 로고    scopus 로고
    • Inheritance and drug response
    • Weinshilboum, R. (2003) Inheritance and drug response. N. Engl. J. Med., 348, 529-537.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 529-537
    • Weinshilboum, R.1
  • 2
    • 33750332747 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics: development, science, and translation
    • Weinshilboum, R.M. and Wang, L. (2006) Pharmacogenetics and pharmacogenomics: development, science, and translation. Annu. Rev. Genomics Hum. Genet., 7, 223-245.
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 223-245
    • Weinshilboum, R.M.1    Wang, L.2
  • 3
    • 33645119580 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions
    • Wang, L. and Weinshilboum, R. (2006) Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions. Oncogene, 25, 1629-1638.
    • (2006) Oncogene , vol.25 , pp. 1629-1638
    • Wang, L.1    Weinshilboum, R.2
  • 4
    • 2942597859 scopus 로고    scopus 로고
    • 'Irinogenetics' and UGT1A: from genotypes to haplotypes
    • Innocenti, F. and Ratain, M.J. (2004) 'Irinogenetics' and UGT1A: from genotypes to haplotypes. Clin. Pharmacol. Ther., 75, 495-500.
    • (2004) Clin. Pharmacol. Ther. , vol.75 , pp. 495-500
    • Innocenti, F.1    Ratain, M.J.2
  • 5
    • 0033608466 scopus 로고    scopus 로고
    • Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
    • Aithal, G.P., Day, C.P., Kesteven, P.J. and Daly, A.K. (1999) Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet, 353, 717-719.
    • (1999) Lancet , vol.353 , pp. 717-719
    • Aithal, G.P.1    Day, C.P.2    Kesteven, P.J.3    Daly, A.K.4
  • 8
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes of BioMedical Research
    • Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, Novartis Institutes of BioMedical Research Saxena, R., Voight, B.F., Lyssenko, V., Burtt, N.P., de Bakker, P.I., Chen, H., Roix, J.J. et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science, 316, 1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3    Burtt, N.P.4    de Bakker, P.I.5    Chen, H.6    Roix, J.J.7
  • 14
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genomewide study. The SEARCH Collaborative Group
    • The SEARCH Collaborative Group
    • The SEARCH Collaborative Group (2008) SLCO1B1 variants and statin-induced myopathy-a genomewide study. The SEARCH Collaborative Group. N. Engl. J. Med., 359, 789-799.
    • (2008) N. Engl. J. Med , vol.359 , pp. 789-799
  • 15
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 highrisk individuals: a randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group (2002) MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 highrisk individuals: a randomised placebo-controlled trial. Lancet, 360, 7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 16
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker, R.H. (2006) The NCI60 human tumour cell line anticancer drug screen. Nat. Rev. Cancer, 6, 813-823.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 17
    • 0345860907 scopus 로고    scopus 로고
    • Transcriptomic analysis of the NCI-60 cancer cell lines
    • Weinstein, J.N. and Pommier, Y. (2003) Transcriptomic analysis of the NCI-60 cancer cell lines. C. R. Biol., 326, 909-920.
    • (2003) C. R. Biol. , vol.326 , pp. 909-920
    • Weinstein, J.N.1    Pommier, Y.2
  • 18
    • 41349116548 scopus 로고    scopus 로고
    • Biochemistry. A postgenomic visual icon
    • Weinstein, J.N. (2008) Biochemistry. A postgenomic visual icon. Science, 319, 1772-1773.
    • (2008) Science , vol.319 , pp. 1772-1773
    • Weinstein, J.N.1
  • 19
    • 79959503826 scopus 로고    scopus 로고
    • The international HapMap project
    • The International HapMap Consortium
    • The International HapMap Consortium (2003) The international HapMap project. Nature, 426, 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 20
    • 3142773390 scopus 로고    scopus 로고
    • Integrating ethics and science in the international HapMap project
    • International HapMap Consortium
    • International HapMap Consortium (2004) Integrating ethics and science in the international HapMap project. Nat. Rev. Genet., 5, 467-475.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 467-475
  • 21
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortiums
    • International HapMap Consortium (2005) A haplotype map of the human genome. Nature, 437, 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 26
    • 33846631884 scopus 로고    scopus 로고
    • Common genetic variants account for differences in gene expression among ethnic groups
    • Spielman, R.S., Bastone, L.A., Burdick, J.T., Morley, M., Ewens, W.J. and Cheung, V.G. (2007) Common genetic variants account for differences in gene expression among ethnic groups. Nat. Genet., 39, 226-231.
    • (2007) Nat. Genet. , vol.39 , pp. 226-231
    • Spielman, R.S.1    Bastone, L.A.2    Burdick, J.T.3    Morley, M.4    Ewens, W.J.5    Cheung, V.G.6
  • 32
    • 40049084479 scopus 로고    scopus 로고
    • Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis
    • Shukla, S.J., Duan, S., Badner, J.A., Wu, X. and Dolan, M.E. (2008) Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis. Pharmacogenet. Genomics, 18, 253-262.
    • (2008) Pharmacogenet. Genomics , vol.18 , pp. 253-262
    • Shukla, S.J.1    Duan, S.2    Badner, J.A.3    Wu, X.4    Dolan, M.E.5
  • 35
    • 1942535076 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells
    • Liu, M.T., Chen, Y.R., Chen, S.C., Hu, C.Y., Lin, C.S., Chang, Y.T., Wang, W.B. and Chen, J.Y. (2004) Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells. Oncogene, 23, 2531-2539.
    • (2004) Oncogene , vol.23 , pp. 2531-2539
    • Liu, M.T.1    Chen, Y.R.2    Chen, S.C.3    Hu, C.Y.4    Lin, C.S.5    Chang, Y.T.6    Wang, W.B.7    Chen, J.Y.8
  • 36
    • 0842326026 scopus 로고    scopus 로고
    • Lytic induction therapy for Epstein-Barr virus-positive B-cell lymphomas
    • Feng, W.H., Hong, G., Delecluse, H.J. and Kenney, S.C. (2004) Lytic induction therapy for Epstein-Barr virus-positive B-cell lymphomas. J. Virol., 78, 1893-1902.
    • (2004) J. Virol. , vol.78 , pp. 1893-1902
    • Feng, W.H.1    Hong, G.2    Delecluse, H.J.3    Kenney, S.C.4
  • 37
    • 0032693405 scopus 로고    scopus 로고
    • Enhanced proteasomal degradation of mutant human thiopurine S-methyltransferase (TPMT) in mammalian cells: mechanism for TPMT protein deficiency inherited by TPMT_2, TPMT_3A.TPMT_3B or TPMT_3C
    • Tai, H.L., Fessing, M.Y., Bonten, E.J., Yanishevsky, Y., d'Azzo, A., Krynetski, E.Y. and Evans, W.E. (1999) Enhanced proteasomal degradation of mutant human thiopurine S-methyltransferase (TPMT) in mammalian cells: mechanism for TPMT protein deficiency inherited by TPMT_2, TPMT_3A, TPMT_3B or TPMT_3C. Pharmacogenetics, 9, 641-650.
    • (1999) Pharmacogenetics , vol.9 , pp. 641-650
    • Tai, H.L.1    Fessing, M.Y.2    Bonten, E.J.3    Yanishevsky, Y.4    d'Azzo, A.5    Krynetski, E.Y.6    Evans, W.E.7
  • 39
    • 0141761407 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradation
    • Wang, L., Sullivan, W., Toft, D. and Weinshilboum, R. (2003) Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradation. Pharmacogenetics, 13, 555-564.
    • (2003) Pharmacogenetics , vol.13 , pp. 555-564
    • Wang, L.1    Sullivan, W.2    Toft, D.3    Weinshilboum, R.4
  • 40
    • 57149132666 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation
    • (in press)
    • Li, F., Wang, L., Burgess, R.J. and Weinshilboum, R.M. (2008) Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation. Pharmacogenet Genomics (in press).
    • (2008) Pharmacogenet Genomics
    • Li, F.1    Wang, L.2    Burgess, R.J.3    Weinshilboum, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.