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Volumn 92, Issue 5, 2012, Pages 651-657

Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: Divergence from in vitro results

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C9; FLURBIPROFEN; PLACEBO; POMEGRANATE EXTRACT;

EID: 84867868709     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.170     Document Type: Article
Times cited : (21)

References (50)
  • 2
    • 34247184192 scopus 로고    scopus 로고
    • Grapefruit juice, a glass full of drug interactions?
    • DOI 10.1038/sj.clpt.6100185, PII 6100185
    • Kirby, B.J. & Unadkat, J.D. Grapefruit juice, a glass full of drug interactions? Clin. Pharmacol. Ther. 81, 631-633 (2007). (Pubitemid 46625123)
    • (2007) Clinical Pharmacology and Therapeutics , vol.81 , Issue.5 , pp. 631-633
    • Kirby, B.J.1    Unadkat, J.D.2
  • 4
    • 79951873878 scopus 로고    scopus 로고
    • Update on drug interactions with grapefruit juice: An evidence-based review
    • Jan
    • Greenblatt, D.J. Update on drug interactions with grapefruit juice: an evidence-based review. Pharmacy Times 76 (Jan), 95-104 (2010).
    • (2010) Pharmacy Times , vol.76 , pp. 95-104
    • Greenblatt, D.J.1
  • 5
    • 44349158401 scopus 로고    scopus 로고
    • Influence of fruit juices on drug disposition: Discrepancies between in vitro and clinical studies
    • DOI 10.1517/17425255.4.4.381
    • Farkas, D. & Greenblatt, D.J. Influence of fruit juices on drug disposition: discrepancies between in vitro and clinical studies. Expert Opin. Drug Metab. Toxicol. 4, 381-393 (2008). (Pubitemid 351728513)
    • (2008) Expert Opinion on Drug Metabolism and Toxicology , vol.4 , Issue.4 , pp. 381-393
    • Farkas, D.1    Greenblatt, D.J.2
  • 12
    • 28844476587 scopus 로고    scopus 로고
    • In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: Qualitative relationships, quantitative predictions, and the rankorder approach
    • Obach, R.S., Walsky, R.L., Venkatakrishnan, K., Houston, J.B. & Tremaine, L.M. In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rankorder approach. Clin. Pharmacol. Ther. 78, 582-592 (2005).
    • (2005) Clin. Pharmacol. Ther. , vol.78 , pp. 582-592
    • Obach, R.S.1    Walsky, R.L.2    Venkatakrishnan, K.3    Houston, J.B.4    Tremaine, L.M.5
  • 13
    • 33748946044 scopus 로고    scopus 로고
    • Prediction of in vivo drug-drug interactions from in vitro data: Factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4
    • DOI 10.2165/00003088-200645100-00006
    • Brown, H.S., Galetin, A., Hallifax, D. & Houston, J.B. Prediction of in vivo drugdrug interactions from in vitro data: factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6, and CYP3A4. Clin. Pharmacokinet. 45, 1035-1050 (2006). (Pubitemid 44436005)
    • (2006) Clinical Pharmacokinetics , vol.45 , Issue.10 , pp. 1035-1050
    • Brown, H.S.1    Galetin, A.2    Hallifax, D.3    Houston, J.B.4
  • 15
    • 33847113977 scopus 로고    scopus 로고
    • Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: Comparison with grapefruit juice
    • DOI 10.1177/0091270006298359
    • Farkas, D. et al. Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice. J. Clin. Pharmacol. 47, 286-294 (2007). (Pubitemid 46294718)
    • (2007) Journal of Clinical Pharmacology , vol.47 , Issue.3 , pp. 286-294
    • Farkas, D.1    Oleson, L.E.2    Zhao, Y.3    Harmatz, J.S.4    Zinny, M.A.5    Court, M.H.6    Greenblatt, D.J.7
  • 16
    • 51349096457 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by ellagitannins
    • Heber, D. Multitargeted therapy of cancer by ellagitannins. Cancer Lett. 269, 262-268 (2008).
    • (2008) Cancer Lett. , vol.269 , pp. 262-268
    • Heber, D.1
  • 17
    • 64049109979 scopus 로고    scopus 로고
    • Pomegranate juice: A heart-healthy fruit juice
    • Basu, A. & Penugonda, K. Pomegranate juice: a heart-healthy fruit juice. Nutr. Rev. 67, 49-56 (2009).
    • (2009) Nutr. Rev. , vol.67 , pp. 49-56
    • Basu, A.1    Penugonda, K.2
  • 18
    • 47549111139 scopus 로고    scopus 로고
    • Therapeutic applications of pomegranate (Punica granatum L.): A review
    • Jurenka, J.S. Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern. Med. Rev. 13, 128-144 (2008).
    • (2008) Altern. Med. Rev. , vol.13 , pp. 128-144
    • Jurenka, J.S.1
  • 19
    • 79960639819 scopus 로고    scopus 로고
    • Antioxidant and antiatherogenic effects of pomegranate
    • Haber, S.L., Joy, J.K. & Largent, R. Antioxidant and antiatherogenic effects of pomegranate. Am. J. Health. Syst. Pharm. 68, 1302-1305 (2011).
    • (2011) Am. J. Health. Syst. Pharm. , vol.68 , pp. 1302-1305
    • Haber, S.L.1    Joy, J.K.2    Largent, R.3
  • 20
    • 79960859812 scopus 로고    scopus 로고
    • The bioactivity of pomegranate: Impact on health and disease
    • Faria, A. & Calhau, C. The bioactivity of pomegranate: impact on health and disease. Crit. Rev. Food Sci. Nutr. 51, 626-634 (2011).
    • (2011) Crit. Rev. Food Sci. Nutr. , vol.51 , pp. 626-634
    • Faria, A.1    Calhau, C.2
  • 21
    • 78049418892 scopus 로고    scopus 로고
    • Fruit polyphenols and CVD risk: A review of human intervention studies
    • Chong, M.F., Macdonald, R. & Lovegrove, J.A. Fruit polyphenols and CVD risk: a review of human intervention studies. Br. J. Nutr. 104 (suppl. 3), S28-S39 (2010).
    • (2010) Br. J. Nutr. , vol.104 , Issue.SUPPL. 3
    • Chong, M.F.1    MacDonald, R.2    Lovegrove, J.A.3
  • 22
    • 77952537236 scopus 로고    scopus 로고
    • Cancer chemoprevention by pomegranate: Laboratory and clinical evidence
    • Adhami, V.M., Khan, N. & Mukhtar, H. Cancer chemoprevention by pomegranate: laboratory and clinical evidence. Nutr. Cancer 61, 811-815 (2009).
    • (2009) Nutr. Cancer , vol.61 , pp. 811-815
    • Adhami, V.M.1    Khan, N.2    Mukhtar, H.3
  • 24
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P4502C9: An enzyme of major importance in human drug metabolism
    • DOI 10.1046/j.1365-2125.1998.00721.x
    • Miners, J.O. & Birkett, D.J. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br. J. Clin. Pharmacol. 45, 525-538 (1998). (Pubitemid 28270907)
    • (1998) British Journal of Clinical Pharmacology , vol.45 , Issue.6 , pp. 525-538
    • Miners, J.O.1    Birkett, D.J.2
  • 25
    • 13944274619 scopus 로고    scopus 로고
    • Clinical and toxicological relevance of CYP2C9: Drug-drug interactions and pharmacogenetics
    • DOI 10.1146/annurev.pharmtox.45.120403.095821
    • Rettie, A.E. & Jones, J.P. Clinical and toxicological relevance of CYP2C9: drugdrug interactions and pharmacogenetics. Annu. Rev. Pharmacol. Toxicol. 45, 477-494 (2005). (Pubitemid 40267790)
    • (2005) Annual Review of Pharmacology and Toxicology , vol.45 , pp. 477-494
    • Rettie, A.E.1    Jones, J.P.2
  • 26
    • 68149149686 scopus 로고    scopus 로고
    • Potential interaction between pomegranate juice and warfarin
    • Komperda, K.E. Potential interaction between pomegranate juice and warfarin. Pharmacotherapy 29, 1002-1006 (2009).
    • (2009) Pharmacotherapy , vol.29 , pp. 1002-1006
    • Komperda, K.E.1
  • 27
    • 74549165578 scopus 로고    scopus 로고
    • Possible interaction between pomegranate juice and warfarin
    • Jarvis, S., Li, C. & Bogle, R.G. Possible interaction between pomegranate juice and warfarin. Emerg. Med. J. 27, 74-75 (2010).
    • (2010) Emerg. Med. J. , vol.27 , pp. 74-75
    • Jarvis, S.1    Li, C.2    Bogle, R.G.3
  • 28
    • 30444445695 scopus 로고    scopus 로고
    • Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: In vitro and clinical studies
    • DOI 10.1016/j.clpt.2005.09.014, PII S0009923605004340
    • Greenblatt, D.J., von Moltke, L.L., Perloff, E.S., Luo, Y., Harmatz, J.S. & Zinny, M.A. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin. Pharmacol. Ther. 79, 125-133 (2006). (Pubitemid 43071237)
    • (2006) Clinical Pharmacology and Therapeutics , vol.79 , Issue.1 , pp. 125-133
    • Greenblatt, D.J.1    Von Moltke, L.L.2    Perloff, E.S.3    Luo, Y.4    Harmatz, J.S.5    Zinny, M.A.6
  • 32
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • DOI 10.1016/S0163-7258(96)00140-4, PII S0163725896001404
    • Kaminsky, L.S. & Zhang, Z.Y. Human P450 metabolism of warfarin. Pharmacol. Ther. 73, 67-74 (1997). (Pubitemid 26425815)
    • (1997) Pharmacology and Therapeutics , vol.73 , Issue.1 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.-Y.2
  • 33
    • 68449095641 scopus 로고    scopus 로고
    • Cranberry juice suppressed the diclofenac metabolism by human liver microsomes, but not in healthy human subjects
    • Ushijima, K. et al. Cranberry juice suppressed the diclofenac metabolism by human liver microsomes, but not in healthy human subjects. Br. J. Clin. Pharmacol. 68, 194-200 (2009).
    • (2009) Br. J. Clin. Pharmacol. , vol.68 , pp. 194-200
    • Ushijima, K.1
  • 34
    • 84866321358 scopus 로고    scopus 로고
    • The warfarin-cranberry juice interaction revisited: A systematic in vitro-in vivo evaluation
    • Ngo, N. et al. The warfarin-cranberry juice interaction revisited: a systematic in vitro-in vivo evaluation. J. Exp. Pharmacol. 2010, 83-91 (2010).
    • (2010) J. Exp. Pharmacol. , vol.2010 , pp. 83-91
    • Ngo, N.1
  • 35
    • 16844373618 scopus 로고    scopus 로고
    • Interaction of warfarin with drugs, natural substances, and foods
    • DOI 10.1177/0091270004271404
    • Greenblatt, D.J. & von Moltke, L.L. Interaction of warfarin with drugs, natural substances, and foods. J. Clin. Pharmacol. 45, 127-132 (2005). (Pubitemid 40490435)
    • (2005) Journal of Clinical Pharmacology , vol.45 , Issue.2 , pp. 127-132
    • Greenblatt, D.J.1    Von Moltke, L.L.2
  • 36
    • 77953516036 scopus 로고    scopus 로고
    • Effect of high-dose cranberry juice on the pharmacodynamics of warfarin in patients
    • Mellen, C.K., Ford, M. & Rindone, J.P. Effect of high-dose cranberry juice on the pharmacodynamics of warfarin in patients. Br. J. Clin. Pharmacol. 70, 139-142 (2010).
    • (2010) Br. J. Clin. Pharmacol. , vol.70 , pp. 139-142
    • Mellen, C.K.1    Ford, M.2    Rindone, J.P.3
  • 37
    • 67650446990 scopus 로고    scopus 로고
    • The absence of an interaction between warfarin and cranberry juice: A randomized, double-blind trial
    • Ansell, J., McDonough, M., Zhao, Y., Harmatz, J.S. & Greenblatt, D.J. The absence of an interaction between warfarin and cranberry juice: a randomized, double-blind trial. J. Clin. Pharmacol. 49, 824-830 (2009).
    • (2009) J. Clin. Pharmacol. , vol.49 , pp. 824-830
    • Ansell, J.1    McDonough, M.2    Zhao, Y.3    Harmatz, J.S.4    Greenblatt, D.J.5
  • 38
    • 77950610651 scopus 로고    scopus 로고
    • Cranberry juice and warfarin: When bad publicity trumps science
    • Zikria, J., Goldman, R. & Ansell, J. Cranberry juice and warfarin: when bad publicity trumps science. Am. J. Med. 123, 384-392 (2010).
    • (2010) Am. J. Med. , vol.123 , pp. 384-392
    • Zikria, J.1    Goldman, R.2    Ansell, J.3
  • 41
    • 0035028935 scopus 로고    scopus 로고
    • Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: Inhibition by sulfaphenazole, omeprazole, and ticlopidine
    • DOI 10.1007/s002280100268
    • Giancarlo, G.M., Venkatakrishnan, K., Granda, B.W., von Moltke, L.L. & Greenblatt, D.J. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine. Eur. J. Clin. Pharmacol. 57, 31-36 (2001). (Pubitemid 32391409)
    • (2001) European Journal of Clinical Pharmacology , vol.57 , Issue.1 , pp. 31-36
    • Giancarlo, G.M.1    Venkatakrishnan, K.2    Granda, B.W.3    Von Moltke, L.L.4    Greenblatt, D.J.5
  • 42
    • 79954504404 scopus 로고    scopus 로고
    • Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam: An open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers
    • Misaka, S. et al. Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam: an open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers. Clin. Ther. 33, 246-252 (2011).
    • (2011) Clin. Ther. , vol.33 , pp. 246-252
    • Misaka, S.1
  • 43
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Scalbert, A. & Williamson, G. Dietary intake and bioavailability of polyphenols. J. Nutr. 130, 2073S-2085S (2000). (Pubitemid 30619386)
    • (2000) Journal of Nutrition , vol.130 , Issue.8 SUPPL.
    • Scalbert, A.1    Williamson, G.2
  • 45
    • 1042290475 scopus 로고    scopus 로고
    • Cellular uptake and metabolism of flavonoids and their metabolites: Implications for their bioactivity
    • DOI 10.1016/j.abb.2003.11.010
    • Spencer, J.P., Abd-el-Mohsen, M.M. & Rice-Evans, C. Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity. Arch. Biochem. Biophys. 423, 148-161 (2004). (Pubitemid 38198224)
    • (2004) Archives of Biochemistry and Biophysics , vol.423 , Issue.1 , pp. 148-161
    • Spencer, J.P.E.1    Abd El Mohsen, M.M.2    Rice-Evans, C.3
  • 46
    • 0031790242 scopus 로고    scopus 로고
    • Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent
    • DOI 10.1016/S0076-6879(99)99017-1
    • Singleton, V.L., Orthofer, R., Lamuela-Ravent, R.M. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. In Methods in Enzymology, Vol. 299: Oxidants and Antioxidants, Part A (ed. L. Packer) 152-178 (Academic Press, New York, 1999). (Pubitemid 28483890)
    • (1998) Methods in Enzymology , vol.299 , pp. 152-178
    • Singleton, V.L.1    Orthofer, R.2    Lamuela-Raventos, R.M.3
  • 47
    • 0034004083 scopus 로고    scopus 로고
    • Effects of the antifungal agents on oxidative drug metabolism. Clinical relevance
    • Venkatakrishnan, K., von Moltke, L.L. & Greenblatt, D.J. Effects of the antifungal agents on oxidative drug metabolism: clinical relevance. Clin. Pharmacokinet. 38, 111-180 (2000). (Pubitemid 30122116)
    • (2000) Clinical Pharmacokinetics , vol.38 , Issue.2 , pp. 111-180
    • Venkatakrishnan, K.1    Von Moltke, L.L.2    Greenblatt, D.J.3
  • 49
    • 78751483916 scopus 로고    scopus 로고
    • Mechanism of cytochrome P450-3A inhibition by ketoconazole
    • Greenblatt, D.J. et al. Mechanism of cytochrome P450-3A inhibition by ketoconazole. J. Pharm. Pharmacol. 63, 214-221 (2011).
    • (2011) J. Pharm. Pharmacol. , vol.63 , pp. 214-221
    • Greenblatt, D.J.1


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