Antioxidant and antiatherogenic effects of pomegranate

American Journal of Health-System Pharmacy

Volumn 68, Issue 14, 2011, Pages 1302-1305

  Haber, Stacy L ^a   Joy, Jamie K ^b   Largent, Roxanne ^c  

^a MIDWESTERN UNIVERSITY   (United States)

^b CANCER TREATMENT CENTERS OF AMERICA   (United States)

^c SACRED HEART MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIATHEROGENIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE 1; ASCORBIC ACID; C PEPTIDE; CARDIOVASCULAR AGENT; CHOLESTEROL; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EZETIMIBE; GLUTATHIONE; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN; MIDAZOLAM; POMEGRANATE EXTRACT; ROSUVASTATIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL GROUP; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; WARFARIN;

ABSENCE OF SIDE EFFECTS; ANGIONEUROTIC EDEMA; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; APPLE JUICE; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD CELL COUNT; BRONCHOSPASM; CARDIOVASCULAR DISEASE; CAROTID ARTERY OBSTRUCTION; CHOLESTEROL BLOOD LEVEL; DRUG CONTRAINDICATION; DRUG INHIBITION; DRUG SAFETY; DYSPNEA; ENZYME BLOOD LEVEL; FAMILIAL HYPERCHOLESTEROLEMIA; HEART MUSCLE PERFUSION; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERSENSITIVITY; INTERNATIONAL NORMALIZED RATIO; ISCHEMIC HEART DISEASE; LIPID BLOOD LEVEL; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; OXIDATION; OXIDATIVE STRESS; POMEGRANATE JUICE; PRIORITY JOURNAL; PRURITUS; RHABDOMYOLYSIS; RHINORRHEA; SIDE EFFECT; STOMACH IRRITATION; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; TRIACYLGLYCEROL BLOOD LEVEL; URINALYSIS; URTICARIA; VITAL SIGN; VITAMIN BLOOD LEVEL; WAIST CIRCUMFERENCE; WEIGHT GAIN;

EID: 79960639819     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp100610     Document Type: Article

References (22)

1. Natural Standard. Pomegranate (Punica granatum). www.naturalstandard.com (accessed 2010 Jun 28).
2. Gruenwald J, Brendler T, Jaenicke C, eds. PDR for herbal medicines. 4th ed. Montvale, NJ: Thomson Healthcare Inc.; 2007.
3. Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis. 2001; 158:195-8. (Pubitemid 32735484)
4. Aviram M, Dornfeld L, Rosenblat M et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 2000; 71:1062-76. (Pubitemid 30230552)
5. Rosenblat M, Hayek T, Aviram M. Antioxidant effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. Atherosclerosis. 2006; 187:363-71. (Pubitemid 43963016)
6. Heber D, Seeram NP, Wyatt H et al. Safety and antioxidant activity of a pomegranate ellagitannin-enriched polyphenol dietary supplement in overweight individuals with increased waist size. J Agric Food Chem. 2007; 55:10050-4. (Pubitemid 350305195)
7. Guo C, Wei J, Yang J et al. Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects. Nutr Res. 2008; 28:72-7.
8. Aviram M, Rosenblat M, Gaitini D et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intimamedia thickness, blood pressure and LDL oxidation. Clin Nutr. 2004; 23:423-33. (Pubitemid 38811681)
9. Esmaillzadeh A, Tahbaz F, Gaieni I et al. Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia. J Med Food. 2004; 7:305-8. (Pubitemid 39299488)
10. Sumner MD, Elliott-Eller M, Weidner G et al. Effects of pomegranate juice consumption in patients with coronary heart disease. Am J Cardiol. 2005; 96:810-4. (Pubitemid 41317656)
11. Abidov M, Jimenez Del Rio M, Ramazanov A et al. Efficiency of pharmacologically-active antioxidant phytomedicine Radical Fruits in treatment of hypercholesterolemia at men. Georgian Med News. 2006; 11:78-83.
12. Davidson MH, Maki KC, Dicklin MR et al. Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease. Am J Cardiol. 2009; 104:936-42.
13. Igea JM, Cuesta J, Cuevas M et al. Adverse reaction to pomegranate ingestion. Allergy. 1991; 46:472-4.
14. Gaig P, Botey J, Gutierrez V et al. Allergy to pomegranate (Punica granatum). J Investig Allergol Clin Immunol. 1992; 2:216-8.
15. Gaig P, Bartolome B, Lleonart R et al. Allergy to pomegranate (Punica granatum). Allergy. 1999; 54:287-8. (Pubitemid 29185293)
16. Enrique E, Utz M, De Mateo JA et al. Allergy to lipid transfer proteins: cross-reactivity among pomegranate, hazelnut, and peanut. Ann Allergy Asthma Immunol. 2006; 96:122-3. (Pubitemid 43152679)
17. Gangemi S, Mistrello G, Roncarlo D et al. Pomegranate-dependent exercise-induced anaphylaxis. J Investig Allergol Clin Immunol. 2008; 18:491-2.
18. Damiani E, Aloia AM, Priore MG et al. Pomegranate (Punica granatum) allergy: clinical and immunological findings. Ann Allergy Asthma Immunol. 2009; 103:178-80.
19. Valseechi R, Reseghetti A, Leghissa P et al. Immediate contact hypersensitivity to pomegranate. Contact Dermatitis. 1998; 38:44-5. (Pubitemid 28059740)
20. Komperda KE. Potential interaction between pomegranate juice and warfarin. Pharmacotherapy. 2009; 29:1002-6.
21. Farkas D, Oleson LE, Zhao Y et al. Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice. J Clin Pharmacol. 2007; 47:286-94. (Pubitemid 46294718)
22. Sorokin AV, Duncan B, Panetta R et al. Rhabdomyolysis associated with pomegranate juice consumption. Am J Cardiol. 2006; 98:705-6. (Pubitemid 44233475)