AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells

International Journal of Oncology

Volumn 41, Issue 5, 2012, Pages 1683-1692

  Tsai, Shih Chang ^a   Lu, Chi Cheng ^b   Lee, Chao Ying ^a   Lin, Yung Chang ^b   Chung, Jing Gung ^a   Kuo, Sheng Chu ^a   Amagaya, Sakae ^a,d   Chen, Fei Na ^a   Chen, Michael Yuanchien ^a,c   Chan, Shih Feng ^a   Yang, Jai Sing ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

AKT; Apoptosis; Bufalin; CAL 27 oral cancer cells; Caspase; Constitutively active; G0 G1 phase arrest

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BUFALIN; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL STIMULATION; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MOUTH CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BUFANOLIDES; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; MOUTH NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84867821938     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1605     Document Type: Article

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