-
1
-
-
0042232133
-
Repressors of androgen and progesterone receptor action
-
DOI 10.1074/jbc.M305153200
-
Agoulnik IU, Krause WC, Bingman WE 3rd, Rahman HT, Amrikachi M, Ayala GE, and Weigel NL (2003) Repressors of androgen and progesterone receptor action. J Biol Chem 278:31136-31148. (Pubitemid 36994629)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 31136-31148
-
-
Agoulnik, I.U.1
Krause, W.C.2
Bingman III, W.E.3
Rahman, H.T.4
Amrikachi, M.5
Ayala, G.E.6
Weigel, N.L.7
-
2
-
-
0034677882
-
Interaction of the corepressor alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita
-
DOI 10.1074/jbc.275.11.7662
-
Altincicek B, Tenbaum SP, Dressel U, Thormeyer D, Renkawitz R, and Baniahmad A (2000) Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita. J Biol Chem 275:7662-7667. (Pubitemid 30159668)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.11
, pp. 7662-7667
-
-
Altincicek, B.1
Tenbaum, S.P.2
Drossel, U.3
Thormeyer, D.4
Renkawitz, R.5
Baniahmad, A.6
-
3
-
-
27144489108
-
Protein database searches using compositionally adjusted substitution matrices
-
DOI 10.1111/j.1742-4658.2005.04945.x
-
Altschul SF, Wootton JC, Gertz EM, Agarwala R, Morgulis A, Schäffer AA, and Yu YK (2005) Protein database searches using compositionally adjusted substitution matrices. FEBS J 272:5101-5109. (Pubitemid 41503143)
-
(2005)
FEBS Journal
, vol.272
, Issue.20
, pp. 5101-5109
-
-
Altschul, S.F.1
Wootton, J.C.2
Gertz, E.M.3
Agarwala, R.4
Morgulis, A.5
Schaffer, A.A.6
Yu, Y.-K.7
-
4
-
-
0034957480
-
Nuclear hormone receptors and gene expression
-
Aranda A and Pascual A (2001) Nuclear hormone receptors and gene expression. Physiol Rev 81:1269-1304. (Pubitemid 32606670)
-
(2001)
Physiological Reviews
, vol.81
, Issue.3
, pp. 1269-1304
-
-
Aranda, A.1
Pascual, A.2
-
5
-
-
4344562884
-
Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
-
Arnold KA, Eichelbaum M, and Burk O (2004) Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor. Nucl Recept 2:1.
-
(2004)
Nucl Recept
, vol.2
, pp. 1
-
-
Arnold, K.A.1
Eichelbaum, M.2
Burk, O.3
-
6
-
-
33847388435
-
CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics
-
DOI 10.1124/dmd.106.012641
-
Auerbach SS, Dekeyser JG, Stoner MA, and Omiecinski CJ (2007) CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics. Drug Metab Dispos 35:428-439. (Pubitemid 46333906)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.3
, pp. 428-439
-
-
Auerbach, S.S.1
DeKeyser, J.G.2
Stoner, M.A.3
Omiecinski, C.J.4
-
7
-
-
0037563788
-
Alternatively spliced isoforms of the human constitutive androstane receptor
-
DOI 10.1093/nar/gkg419
-
Auerbach SS, Ramsden R, Stoner MA, Verlinde C, Hassett C, and Omiecinski CJ (2003) Alternatively spliced isoforms of the human constitutive androstane receptor. Nucleic Acids Res 31:3194-3207. (Pubitemid 37441779)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.12
, pp. 3194-3207
-
-
Auerbach, S.S.1
Ramsden, R.2
Stoner, M.A.3
Verlinde, C.4
Hassett, C.5
Omiecinski, C.J.6
-
8
-
-
27544477927
-
Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3)
-
DOI 10.1124/mol.105.013417
-
Auerbach SS, Stoner MA, Su S, and Omiecinski CJ (2005) Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3). Mol Pharmacol 68:1239-1253. (Pubitemid 41539981)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.5
, pp. 1239-1253
-
-
Auerbach, S.S.1
Stoner, M.A.2
Su, S.3
Omiecinski, C.J.4
-
9
-
-
1242337303
-
Repression of CAR-Mediated Transactivation of CYP2B Genes by the Orphan Nuclear Receptor, Short Heterodimer Partner (SHP)
-
DOI 10.1089/104454904322759894
-
Bae Y, Kemper JK, and Kemper B (2004) Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP). DNA Cell Biol 23:81-91. (Pubitemid 38221925)
-
(2004)
DNA and Cell Biology
, vol.23
, Issue.2
, pp. 81-91
-
-
Bae, Y.1
Kemper, J.K.2
Kemper, B.3
-
10
-
-
0028210426
-
A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements
-
Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, and Moore DD (1994) A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. Mol Cell Biol 14:1544-1552. (Pubitemid 24074550)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.3
, pp. 1544-1552
-
-
Baes, M.1
Gulick, T.2
Choi, H.-S.3
Martinolu, M.G.4
Simha, D.5
Moore, D.D.6
-
11
-
-
0033513582
-
Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: Discovery of peptide antagonists of estrogen receptors alpha and beta
-
Chang C, Norris JD, Grøn H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, and McDonnell DP (1999) Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol 19:8226-8239. (Pubitemid 30414017)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.12
, pp. 8226-8239
-
-
Chang, C.-Y.1
Norris, J.D.2
Gron, H.3
Paige, L.A.4
Hamilton, P.T.5
Kenan, D.J.6
Fowlkes, D.7
McDonnell, D.P.8
-
12
-
-
83555174696
-
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism
-
Chen T, Chen Q, Xu Y, Zhou Q, Zhu J, Zhang H, Wu Q, Xu J, and Yu C (2012) SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism. J Hepatol 56:210-217.
-
(2012)
J Hepatol
, vol.56
, pp. 210-217
-
-
Chen, T.1
Chen, Q.2
Xu, Y.3
Zhou, Q.4
Zhu, J.5
Zhang, H.6
Wu, Q.7
Xu, J.8
Yu, C.9
-
13
-
-
0031895798
-
Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
-
Crawford PA, Dorn C, Sadovsky Y, and Milbrandt J (1998) Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Mol Cell Biol 18:2949-2956. (Pubitemid 28183464)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.5
, pp. 2949-2956
-
-
Crawford, P.A.1
Dorn, C.2
Sadovsky, Y.3
Milbrandt, J.4
-
14
-
-
79953107915
-
Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor
-
DeKeyser JG, Laurenzana EM, Peterson EC, Chen T, and Omiecinski CJ (2011) Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor. Toxicol Sci 120:381-391.
-
(2011)
Toxicol Sci
, vol.120
, pp. 381-391
-
-
DeKeyser, J.G.1
Laurenzana, E.M.2
Peterson, E.C.3
Chen, T.4
Omiecinski, C.J.5
-
15
-
-
64249112729
-
Di(2-ethylhexyl) phthalate is a highly potent agonist for the human constitutive androstane receptor splice variant CAR2
-
DeKeyser JG, Stagliano MC, Auerbach SS, Prabhu KS, Jones AD, and Omiecinski CJ (2009) Di(2-ethylhexyl) phthalate is a highly potent agonist for the human constitutive androstane receptor splice variant CAR2. Mol Pharmacol 75:1005-1013.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1005-1013
-
-
DeKeyser, J.G.1
Stagliano, M.C.2
Auerbach, S.S.3
Prabhu, K.S.4
Jones, A.D.5
Omiecinski, C.J.6
-
16
-
-
0032230231
-
Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): Multiple motifs with different binding specificities
-
Ding XF, Anderson CM, Ma H, Hong H, Uht RM, Kushner PJ, and Stallcup MR (1998) Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities. Mol Endocrinol 12:302-313. (Pubitemid 30658245)
-
(1998)
Molecular Endocrinology
, vol.12
, Issue.2
, pp. 302-313
-
-
Ding, X.F.1
Anderson, C.M.2
Ma, H.3
Hong, H.4
Uht, R.M.5
Kushner, P.J.6
Stallcup, M.R.7
-
17
-
-
73249140987
-
Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease
-
Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, et al. (2009) Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. Proc Natl Acad Sci USA 106:18831-18836.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18831-18836
-
-
Dong, B.1
Saha, P.K.2
Huang, W.3
Chen, W.4
Abu-Elheiga, L.A.5
Wakil, S.J.6
Stevens, R.D.7
Ilkayeva, O.8
Newgard, C.B.9
Chan, L.10
-
18
-
-
0036311095
-
A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity
-
DOI 10.1128/MCB.22.15.5270-5280.2002
-
Dussault I, Lin M, Hollister K, Fan M, Termini J, Sherman MA, and Forman BM (2002) A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity. Mol Cell Biol 22:5270-5280. (Pubitemid 34755741)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.15
, pp. 5270-5280
-
-
Dussault, I.1
Lin, M.2
Hollister, K.3
Fan, M.4
Termini, J.5
Sherman, M.A.6
Forman, B.M.7
-
19
-
-
84861189202
-
Ligand-independent actions of the orphan receptors/corepressors DAX-1 and SHP in metabolism, reproduction and disease
-
Ehrlund A and Treuter E (2012) Ligand-independent actions of the orphan receptors/corepressors DAX-1 and SHP in metabolism, reproduction and disease. J Steroid Biochem Mol Biol 130:169-179.
-
(2012)
J Steroid Biochem Mol Biol
, vol.130
, pp. 169-179
-
-
Ehrlund, A.1
Treuter, E.2
-
20
-
-
0032497544
-
Androstane metabolites bind to and deactivate the nuclear receptor CAR- beta
-
DOI 10.1038/26996
-
Forman BM, Tzameli I, Choi HS, Chen J, Simha D, Seol W, Evans RM, and Moore DD (1998) Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature 395:612-615. (Pubitemid 28475716)
-
(1998)
Nature
, vol.395
, Issue.6702
, pp. 612-615
-
-
Forman, B.M.1
Tzameli, I.2
Choi, H.-S.3
Chen, J.4
Simha, D.5
Seol, W.6
Evans, R.M.7
Moore, D.D.8
-
21
-
-
49549123574
-
Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures
-
Goyak KM, Johnson MC, Strom SC, and Omiecinski CJ (2008) Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures. Toxicol Appl Pharmacol 231:216-224.
-
(2008)
Toxicol Appl Pharmacol
, vol.231
, pp. 216-224
-
-
Goyak, K.M.1
Johnson, M.C.2
Strom, S.C.3
Omiecinski, C.J.4
-
22
-
-
0242665373
-
Complementary Roles of Farnesoid X Receptor, Pregnane X Receptor, and Constitutive Androstane Receptor in Protection against Bile Acid Toxicity
-
DOI 10.1074/jbc.M307145200
-
Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, and Sinal CJ (2003) Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. J Biol Chem 278:45062-45071. (Pubitemid 37432638)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45062-45071
-
-
Guo, G.L.1
Lambert, G.2
Negishi, M.3
Ward, J.M.4
Brewer Jr., H.B.5
Kliewer, S.A.6
Gonzalez, F.J.7
Sinal, C.J.8
-
23
-
-
0035794168
-
Core LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors
-
Heery DM, Hoare S, Hussain S, Parker MG, and Sheppard H (2001) Core LXXLL motif sequences in CREB-binding protein, SRC1, and RIP140 define affinity and selectivity for steroid and retinoid receptors. J Biol Chem 276:6695-6702.
-
(2001)
J Biol Chem
, vol.276
, pp. 6695-6702
-
-
Heery, D.M.1
Hoare, S.2
Hussain, S.3
Parker, M.G.4
Sheppard, H.5
-
24
-
-
0030986236
-
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
-
DOI 10.1038/42750
-
Heery DM, Kalkhoven E, Hoare S, and Parker MG (1997) A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387:733-736. (Pubitemid 27270617)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 733-736
-
-
Heery, D.M.1
Kalkhoven, E.2
Hoare, S.3
Parker, M.G.4
-
25
-
-
0036192044
-
Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1
-
DOI 10.1210/me.16.3.515
-
Holter E, Kotaja N, Mäkela S, Strauss L, Kietz S, Jänne OA, Gustafsson JA, Palvimo JJ, and Treuter E (2002) Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1. Mol Endocrinol 16:515-528. (Pubitemid 34214571)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.3
, pp. 515-528
-
-
Holter, E.1
Kotaja, N.2
Makela, S.3
Strauss, L.4
Kietz, S.5
Janne, O.A.6
Gustafsson, J.-A.7
Palvimo, J.J.8
Treuter, E.9
-
26
-
-
0038798874
-
Drug-activated nuclear receptors CAR and PXR
-
DOI 10.1080/07853890310008224
-
Honkakoski P, Sueyoshi T, and Negishi M (2003) Drug-activated nuclear receptors CAR and PXR. Ann Med 35:172-182. (Pubitemid 36765230)
-
(2003)
Annals of Medicine
, vol.35
, Issue.3
, pp. 172-182
-
-
Honkakoski, P.1
Sueyoshi, T.2
Negishi, M.3
-
27
-
-
0033523917
-
The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
-
Hu X and Lazar MA (1999) The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature 402:93-96.
-
(1999)
Nature
, vol.402
, pp. 93-96
-
-
Hu, X.1
Lazar, M.A.2
-
28
-
-
0031020234
-
DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita
-
Ito M, Yu R, and Jameson JL (1997) DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita. Mol Cell Biol 17:1476-1483. (Pubitemid 27097377)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.3
, pp. 1476-1483
-
-
Ito, M.1
Yu, R.2
Jameson, J.L.3
-
29
-
-
70249090729
-
Nuclear receptor regulation of stemness and stem cell differentiation
-
Jeong Y and Mangelsdorf DJ (2009) Nuclear receptor regulation of stemness and stem cell differentiation. Exp Mol Med 41:525-537.
-
(2009)
Exp Mol Med
, vol.41
, pp. 525-537
-
-
Jeong, Y.1
Mangelsdorf, D.J.2
-
30
-
-
42249108359
-
The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARgamma
-
Kim GS, Lee GY, Nedumaran B, Park YY, Kim KT, Park SC, Lee YC, Kim JB, and Choi HS (2008) The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARgamma. Biochem Biophys Res Commun 370:264-268.
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 264-268
-
-
Kim, G.S.1
Lee, G.Y.2
Nedumaran, B.3
Park, Y.Y.4
Kim, K.T.5
Park, S.C.6
Lee, Y.C.7
Kim, J.B.8
Choi, H.S.9
-
31
-
-
0032230234
-
Molecular cloning of xSRC-3, a novel transcription coactivator from Xenopus, that is related to AIB1, p/CIP, and TIF2
-
Kim HJ, Lee SK, Na SY, Choi HS, and Lee JW (1998) Molecular cloning of xSRC-3, a novel transcription coactivator from Xenopus, that is related to AIB1, p/CIP, and TIF2. Mol Endocrinol 12:1038-1047.
-
(1998)
Mol Endocrinol
, vol.12
, pp. 1038-1047
-
-
Kim, H.J.1
Lee, S.K.2
Na, S.Y.3
Choi, H.S.4
Lee, J.W.5
-
32
-
-
4444246000
-
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
-
DOI 10.1128/MCB.24.18.7931-7940.2004
-
Kodama S, Koike C, Negishi M, and Yamamoto Y (2004) Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 24:7931-7940. (Pubitemid 39167443)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 7931-7940
-
-
Kodama, S.1
Koike, C.2
Negishi, M.3
Yamamoto, Y.4
-
33
-
-
42249111748
-
The roles of nuclear receptors CAR and PXR in hepatic energy metabolism
-
Konno Y, Negishi M, and Kodama S (2008) The roles of nuclear receptors CAR and PXR in hepatic energy metabolism. Drug Metab Pharmacokinet 23:8-13.
-
(2008)
Drug Metab Pharmacokinet
, vol.23
, pp. 8-13
-
-
Konno, Y.1
Negishi, M.2
Kodama, S.3
-
34
-
-
0043268895
-
DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation
-
DOI 10.1210/me.2003-0159
-
Lalli E and Sassone-Corsi P (2003) DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation. Mol Endocrinol 17:1445-1453. (Pubitemid 36930462)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.8
, pp. 1445-1453
-
-
Lalli, E.1
Sassone-Corsi, P.2
-
35
-
-
6344266966
-
Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences
-
DOI 10.1124/jpet.104.069310
-
Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, and Schuetz E (2004) Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. J Pharmacol Exp Ther 311:811-821. (Pubitemid 39391571)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.311
, Issue.2
, pp. 811-821
-
-
Lamba, J.K.1
Lamba, V.2
Yasuda, K.3
Lin, Y.S.4
Assem, M.5
Thompson, E.6
Strom, S.7
Schuetz, E.G.8
-
36
-
-
0033986961
-
The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: Two mechanisms for repression
-
Lee YK, Dell H, Dowhan DH, Hadzopoulou-Cladaras M, and Moore DD (2000) The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression. Mol Cell Biol 20:187-195. (Pubitemid 30002560)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.1
, pp. 187-195
-
-
Lee, Y.-K.1
Dell, H.2
Dowhan, D.H.3
Hadzopoulou-Cladaras, M.4
Moore, D.D.5
-
37
-
-
34249793707
-
Structure and Function of the Atypical Orphan Nuclear Receptor Small Heterodimer Partner
-
DOI 10.1016/S0074-7696(07)61003-1, PII S0074769607610031, A Survey of Cell Biology
-
Lee YS, Chanda D, Sim J, Park YY, and Choi HS (2007) Structure and function of the atypical orphan nuclear receptor small heterodimer partner. Int Rev Cytol 261:117-158. (Pubitemid 46856618)
-
(2007)
International Review of Cytology
, vol.261
, pp. 117-158
-
-
Lee, Y.1
Chanda, D.2
Sim, J.3
Park, Y.4
Choi, H.5
-
38
-
-
24344436674
-
Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein
-
DOI 10.1210/me.2004-0534
-
Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, and Carlberg C (2005) Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein. Mol Endocrinol 19:2258-2272. (Pubitemid 41252821)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.9
, pp. 2258-2272
-
-
Lempiainen, H.1
Molnar, F.2
Gonzalez, M.M.3
Perakyla, M.4
Carlberg, C.5
-
39
-
-
47949111469
-
The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl- methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor
-
Li L, Chen T, Stanton JD, Sueyoshi T, Negishi M, and Wang H (2008) The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3- isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor. Mol Pharmacol 74:443-453.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 443-453
-
-
Li, L.1
Chen, T.2
Stanton, J.D.3
Sueyoshi, T.4
Negishi, M.5
Wang, H.6
-
40
-
-
23044510503
-
Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor
-
DOI 10.1016/j.molcel.2005.06.026, PII S1097276505014292
-
Li Y, Suino K, Daugherty J, and Xu HE (2005) Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor. Mol Cell 19:367-380. (Pubitemid 41074892)
-
(2005)
Molecular Cell
, vol.19
, Issue.3
, pp. 367-380
-
-
Li, Y.1
Suino, K.2
Daugherty, J.3
Xu, H.E.4
-
41
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
DOI 10.1074/jbc.M300138200
-
Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, et al. (2003) Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J Biol Chem 278:17277-17283. (Pubitemid 36799610)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
Stoltz, C.A.7
Kliewer, S.A.8
Lambert, M.H.9
Willson, T.M.10
Moore, J.T.11
-
42
-
-
51449107194
-
Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice
-
Masson D, Qatanani M, Sberna AL, Xiao R, Pais de Barros JP, Grober J, Deckert V, Athias A, Gambert P, Lagrost L, et al. (2008) Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice. J Lipid Res 49:1682-1691.
-
(2008)
J Lipid Res
, vol.49
, pp. 1682-1691
-
-
Masson, D.1
Qatanani, M.2
Sberna, A.L.3
Xiao, R.4
Pais De Barros, J.P.5
Grober, J.6
Deckert, V.7
Athias, A.8
Gambert, P.9
Lagrost, L.10
-
43
-
-
0037135532
-
Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo
-
DOI 10.1074/jbc.M200051200
-
Min G, Kemper JK, and Kemper B (2002) Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo. J Biol Chem 277:26356-26363. (Pubitemid 34967128)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 26356-26363
-
-
Min, G.1
Kim, K.J.2
Kemper, B.3
-
44
-
-
0035310906
-
Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1
-
DOI 10.1042/0264-6021:3550071
-
Muangmoonchai R, Smirlis D, Wong SC, Edwards M, Phillips IR, and Shephard EA (2001) Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1. Biochem J 355:71-78. (Pubitemid 32304236)
-
(2001)
Biochemical Journal
, vol.355
, Issue.1
, pp. 71-78
-
-
Muangmoonchai, R.1
Smirlis, D.2
Wong, S.-C.3
Edwards, M.4
Phillips, I.R.5
Shephard, E.A.6
-
45
-
-
70350463602
-
DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression
-
Nedumaran B, Hong S, Xie YB, Kim YH, Seo WY, Lee MW, Lee CH, Koo SH, and Choi HS (2009) DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression. J Biol Chem 284:27511-27523.
-
(2009)
J Biol Chem
, vol.284
, pp. 27511-27523
-
-
Nedumaran, B.1
Hong, S.2
Xie, Y.B.3
Kim, Y.H.4
Seo, W.Y.5
Lee, M.W.6
Lee, C.H.7
Koo, S.H.8
Choi, H.S.9
-
46
-
-
77950589655
-
Orphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis
-
Nedumaran B, Kim GS, Hong S, Yoon YS, Kim YH, Lee CH, Lee YC, Koo SH, and Choi HS (2010) Orphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis. J Biol Chem 285:9221-9232.
-
(2010)
J Biol Chem
, vol.285
, pp. 9221-9232
-
-
Nedumaran, B.1
Kim, G.S.2
Hong, S.3
Yoon, Y.S.4
Kim, Y.H.5
Lee, C.H.6
Lee, Y.C.7
Koo, S.H.8
Choi, H.S.9
-
47
-
-
26244433172
-
DAX1 origin, function, and novel role
-
DOI 10.1016/j.ymgme.2005.07.019, PII S1096719205002167, ASHG 2005 Meeting Salt Lake City
-
Niakan KK and McCabe ER (2005) DAX1 origin, function, and novel role. Mol Genet Metab 86:70-83. (Pubitemid 41412162)
-
(2005)
Molecular Genetics and Metabolism
, vol.86
, Issue.1-2
, pp. 70-83
-
-
Niakan, K.K.1
McCabe, E.R.B.2
-
48
-
-
2342447392
-
Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1
-
DOI 10.1210/me.2003-0339
-
Park YY, Kim HJ, Kim JY, Kim MY, Song KH, Cheol Park K, Yu KY, Shong M, Kim KH, and Choi HS (2004) Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1. Mol Endocrinol 18:1082-1095. (Pubitemid 38591276)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.5
, pp. 1082-1095
-
-
Park, Y.-Y.1
Kim, H.-J.2
Kim, J.-Y.3
Kim, M.-Y.4
Song, K.-H.5
Park, K.C.6
Yu, K.-Y.7
Shong, M.8
Kim, K.-H.9
Choi, H.-S.10
-
49
-
-
12244277409
-
Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: Identification of a distal glucocorticoid response element
-
DOI 10.1210/me.2002-0244
-
Pascussi JM, Busson-Le Coniat M, Maurel P, and Vilarem MJ (2003) Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: identification of a distal glucocorticoid response element. Mol Endocrinol 17:42-55. (Pubitemid 36132658)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.1
, pp. 42-55
-
-
Pascussi, J.M.1
Busson-Le, C.M.2
Maurel, P.3
Vilarem, M.-J.4
-
50
-
-
0033664347
-
Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation
-
Pascussi JM, Gerbal-Chaloin S, Fabre JM, Maurel P, and Vilarem MJ (2000) Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation. Mol Pharmacol 58:1441-1450.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1441-1450
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Fabre, J.M.3
Maurel, P.4
Vilarem, M.J.5
-
51
-
-
0033572656
-
Molecular determinants of nuclear receptor-corepressor interaction
-
DOI 10.1101/gad.13.24.3198
-
Perissi V, Staszewski LM, McInerney EM, Kurokawa R, Krones A, Rose DW, Lambert MH, Milburn MV, Glass CK, and Rosenfeld MG (1999) Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev 13:3198-3208. (Pubitemid 30030442)
-
(1999)
Genes and Development
, vol.13
, Issue.24
, pp. 3198-3208
-
-
Perissi, V.1
Staszewski, L.M.2
McInerney, E.M.3
Kurokawa, R.4
Krones, A.5
Rose, D.W.6
Lambert, M.H.7
Milburn, M.V.8
Glass, C.K.9
Rosenfeld, M.G.10
-
52
-
-
40549086299
-
Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes
-
DOI 10.1097/FPC.0b013e3282f706e0, PII 0121301120080400000006
-
Roth A, Looser R, Kaufmann M, and Meyer UA (2008) Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. Pharmacogenet Genomics 18:325-337. (Pubitemid 351367526)
-
(2008)
Pharmacogenetics and Genomics
, vol.18
, Issue.4
, pp. 325-337
-
-
Roth, A.1
Looser, R.2
Kaufmann, M.3
Meyer, U.A.4
-
53
-
-
57449090890
-
The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1
-
Sablin EP, Woods A, Krylova IN, Hwang P, Ingraham HA, and Fletterick RJ (2008) The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1. Proc Natl Acad Sci USA 105:18390-18395.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18390-18395
-
-
Sablin, E.P.1
Woods, A.2
Krylova, I.N.3
Hwang, P.4
Ingraham, H.A.5
Fletterick, R.J.6
-
54
-
-
0142089732
-
Alternative splicing within the ligand binding domain of the human constitutive androstane receptor
-
DOI 10.1016/j.ymgme.2003.08.013
-
Savkur RS, Wu Y, Bramlett KS, Wang M, Yao S, Perkins D, Totten M, Searfoss G 3rd, Ryan TP, Su EW, et al. (2003) Alternative splicing within the ligand binding domain of the human constitutive androstane receptor. Mol Genet Metab 80:216-226. (Pubitemid 37272248)
-
(2003)
Molecular Genetics and Metabolism
, vol.80
, Issue.1-2
, pp. 216-226
-
-
Savkur, R.S.1
Wu, Y.2
Bramlett, K.S.3
Wang, M.4
Yao, S.5
Perkins, D.6
Totten, M.7
Searfoss III, G.8
Ryan, T.P.9
Su, E.W.10
Burris, T.P.11
-
55
-
-
0030001371
-
An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors
-
Seol W, Choi HS, and Moore DD (1996) An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science 272:1336-1339. (Pubitemid 26199974)
-
(1996)
Science
, vol.272
, Issue.5266
, pp. 1336-1339
-
-
Seol, W.1
Choi, H.-S.2
Moore, D.D.3
-
56
-
-
0038514189
-
Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1alpha: A possible link between xenobiotic response and nutritional state
-
DOI 10.1074/jbc.M212859200
-
Shiraki T, Sakai N, Kanaya E, and Jingami H (2003) Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state. J Biol Chem 278:11344-11350. (Pubitemid 36792692)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11344-11350
-
-
Shiraki, T.1
Sakai, N.2
Kanaya, E.3
Jingami, H.4
-
57
-
-
3543119042
-
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
-
DOI 10.1210/me.2004-0043
-
Song KH, Park YY, Park KC, Hong CY, Park JH, Shong M, Lee K, and Choi HS (2004) The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation. Mol Endocrinol 18:1929-1940. (Pubitemid 39022610)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.8
, pp. 1929-1940
-
-
Song, K.-H.1
Park, Y.-Y.2
Ki, C.P.3
Cheol, Y.H.4
Jin, H.P.5
Shong, M.6
Lee, K.7
Choi, H.-S.8
-
58
-
-
0033960595
-
A novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic hypogonadism
-
Tabarin A, Achermann JC, Recan D, Bex V, Bertagna X, Christin-Maitre S, Ito M, Jameson JL, and Bouchard P (2000) A novel mutation in DAX1 causes delayed-onset adrenal insufficiency and incomplete hypogonadotropic hypogonadism. J Clin Invest 105:321-328. (Pubitemid 30094452)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.3
, pp. 321-328
-
-
Tabarin, A.1
Achermann, J.C.2
Recan, D.3
Bex, V.4
Bertagna, X.5
Christin-Maitre, S.6
Ito, M.7
Jameson, J.L.8
Bouchard, P.9
-
59
-
-
33847024555
-
CAR and PXR: The xenobiotic-sensing receptors
-
DOI 10.1016/j.steroids.2006.12.006, PII S0039128X06002649
-
Timsit YE and Negishi M (2007) CAR and PXR: the xenobiotic-sensing receptors. Steroids 72:231-246. (Pubitemid 46273513)
-
(2007)
Steroids
, vol.72
, Issue.3
, pp. 231-246
-
-
Timsit, Y.E.1
Negishi, M.2
-
60
-
-
18044365802
-
Conformational adaptation of nuclear receptor ligand binding domains to agonists: Potential for novel approaches to ligand design
-
DOI 10.1016/j.jsbmb.2005.01.004, Proceedings of the 16th Internatioanl Symposium of the Journal of Steroid Biochemistry and Molecular Biology
-
Togashi M, Borngraeber S, Sandler B, Fletterick RJ, Webb P, and Baxter JD (2005) Conformational adaptation of nuclear receptor ligand binding domains to agonists: potential for novel approaches to ligand design. J Steroid Biochem Mol Biol 93:127-137. (Pubitemid 40602485)
-
(2005)
Journal of Steroid Biochemistry and Molecular Biology
, vol.93
, Issue.2-5
, pp. 127-137
-
-
Togashi, M.1
Borngraeber, S.2
Sandler, B.3
Fletterick, R.J.4
Webb, P.5
Baxter, J.D.6
-
61
-
-
19944372389
-
A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer
-
DOI 10.1016/j.molcel.2004.11.042, PII S1097276504007579
-
Xu RX, Lambert MH, Wisely BB, Warren EN, Weinert EE, Waitt GM, Williams JD, Collins JL, Moore LB, Willson TM, et al. (2004) A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer. Mol Cell 16:919-928. (Pubitemid 40018402)
-
(2004)
Molecular Cell
, vol.16
, Issue.6
, pp. 919-928
-
-
Xu, R.X.1
Lambert, M.H.2
Wisely, B.B.3
Warren, E.N.4
Weinert, E.E.5
Waitt, G.M.6
Williams, J.D.7
Collins, J.L.8
Moore, L.B.9
Willson, T.M.10
Moore, J.T.11
-
62
-
-
0028558750
-
An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita
-
Zanaria E, Muscatelli F, Bardoni B, Strom TM, Guioli S, Guo W, Lalli E, Moser C, Walker AP, and McCabe ER (1994) An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature 372:635-641.
-
(1994)
Nature
, vol.372
, pp. 635-641
-
-
Zanaria, E.1
Muscatelli, F.2
Bardoni, B.3
Strom, T.M.4
Guioli, S.5
Guo, W.6
Lalli, E.7
Moser, C.8
Walker, A.P.9
McCabe, E.R.10
-
63
-
-
0034704063
-
DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors
-
DOI 10.1074/jbc.C000567200
-
Zhang H, Thomsen JS, Johansson L, Gustafsson JA, and Treuter E (2000) DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors. J Biol Chem 275:39855-39859. (Pubitemid 32065755)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.51
, pp. 39855-39859
-
-
Zhang, H.1
Thomsen, J.S.2
Johansson, L.3
Gustafsson, J.-A.4
Treuter, E.5
-
64
-
-
46349107847
-
DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner
-
DOI 10.1210/me.2007-0273
-
Zhou J, Oakley RH, and Cidlowski JA (2008) DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner. Mol Endocrinol 22:1521-1534. (Pubitemid 351920388)
-
(2008)
Molecular Endocrinology
, vol.22
, Issue.7
, pp. 1521-1534
-
-
Zhou, J.1
Oakley, R.H.2
Cidlowski, J.A.3
|