-
1
-
-
0034847930
-
Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis
-
10.1002/bit.1154, 11505384
-
Dauner M, Bailey JE, Sauer U. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis. Biotechnol Bioeng 2001, 76:144-156. 10.1002/bit.1154, 11505384.
-
(2001)
Biotechnol Bioeng
, vol.76
, pp. 144-156
-
-
Dauner, M.1
Bailey, J.E.2
Sauer, U.3
-
2
-
-
33644684617
-
A new substrate cycle in plants. Evidence for a high glucose-phosphate-to-glucose turnover from in vivo steady-state and pulse-labeling experiments with [13C]glucose and [14C]glucose
-
Alonso AP, Vigeolas H, Raymond P, Rolin D, Dieuaide-Noubhani M. A new substrate cycle in plants. Evidence for a high glucose-phosphate-to-glucose turnover from in vivo steady-state and pulse-labeling experiments with [13C]glucose and [14C]glucose. Plant Physiol 2005, 38:2220-2232.
-
(2005)
Plant Physiol
, vol.38
, pp. 2220-2232
-
-
Alonso, A.P.1
Vigeolas, H.2
Raymond, P.3
Rolin, D.4
Dieuaide-Noubhani, M.5
-
3
-
-
0015850193
-
Estimation of the fructose diphosphatase-phosphofructokinase substrate cycle in the flight muscle of Bombus affinis
-
1177847, 16742821
-
Clark MG, Bloxham DP, Holland PC, Lardy HA. Estimation of the fructose diphosphatase-phosphofructokinase substrate cycle in the flight muscle of Bombus affinis. Biochem J 1973, 134:589-597. 1177847, 16742821.
-
(1973)
Biochem J
, vol.134
, pp. 589-597
-
-
Clark, M.G.1
Bloxham, D.P.2
Holland, P.C.3
Lardy, H.A.4
-
4
-
-
0015901928
-
Isotopic evidence for futile cycles in liver cells
-
10.1016/0006-291X(73)90811-5, 4356656
-
Clark DG, Rognstad R, Katz J. Isotopic evidence for futile cycles in liver cells. Biochem Biophys Res Commun 1973, 54:1141-1148. 10.1016/0006-291X(73)90811-5, 4356656.
-
(1973)
Biochem Biophys Res Commun
, vol.54
, pp. 1141-1148
-
-
Clark, D.G.1
Rognstad, R.2
Katz, J.3
-
5
-
-
0017154480
-
Substrate cycles in metabolic regulation and in heat generation
-
Newsholme EA, Crabtree B. Substrate cycles in metabolic regulation and in heat generation. Biochem Soc Symp 1976, 41:61-110.
-
(1976)
Biochem Soc Symp
, vol.41
, pp. 61-110
-
-
Newsholme, E.A.1
Crabtree, B.2
-
6
-
-
0021266684
-
Substrate cycles: their role in improving sensitivity in metabolic control
-
Newsholme EA, Challiss RAJ, Crabtree B. Substrate cycles: their role in improving sensitivity in metabolic control. Trends Biochem Sci 1984, 9:277-280.
-
(1984)
Trends Biochem Sci
, vol.9
, pp. 277-280
-
-
Newsholme, E.A.1
Challiss, R.A.J.2
Crabtree, B.3
-
7
-
-
0016137074
-
On the use of [3H, 14C]labelled glucose in the study of the so-called "futile cycles" in liver and muscle
-
10.1016/S0006-291X(74)80453-5, 4836264
-
Hue L, Hers HG. On the use of [3H, 14C]labelled glucose in the study of the so-called "futile cycles" in liver and muscle. Biochem Biophys Res Commun 1974, 58:532-539. 10.1016/S0006-291X(74)80453-5, 4836264.
-
(1974)
Biochem Biophys Res Commun
, vol.58
, pp. 532-539
-
-
Hue, L.1
Hers, H.G.2
-
8
-
-
0017035084
-
Effects of hormones and of ethanol on the fructose 6-P-fructose 1,6-P2 futile cycle during gluconeogenesis in the liver
-
10.1016/0003-9861(76)90447-1, 1015825
-
Rognstad R, Katz J. Effects of hormones and of ethanol on the fructose 6-P-fructose 1,6-P2 futile cycle during gluconeogenesis in the liver. Arch Biochem Biophys 1976, 177:337-345. 10.1016/0003-9861(76)90447-1, 1015825.
-
(1976)
Arch Biochem Biophys
, vol.177
, pp. 337-345
-
-
Rognstad, R.1
Katz, J.2
-
9
-
-
0028036096
-
Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices
-
Zupke C, Stephanopoulos G. Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices. Biotechnol Prog 1994, 10:489-498.
-
(1994)
Biotechnol Prog
, vol.10
, pp. 489-498
-
-
Zupke, C.1
Stephanopoulos, G.2
-
10
-
-
0343267841
-
Bidirectional Reaction Steps in Metabolic Networks: III. Explicit Solution and Analysis of Isotopomer Labeling Systems
-
10.1002/(SICI)1097-0290(1999)66:2<69::AID-BIT1>3.0.CO;2-6, 10567066
-
Wiechert W, Moellney M, Isermann N, Wurzel M, de Graaf AA. Bidirectional Reaction Steps in Metabolic Networks: III. Explicit Solution and Analysis of Isotopomer Labeling Systems. Biotechnol Bioeng 1999, 66:69-85. 10.1002/(SICI)1097-0290(1999)66:2<69::AID-BIT1>3.0.CO;2-6, 10567066.
-
(1999)
Biotechnol Bioeng
, vol.66
, pp. 69-85
-
-
Wiechert, W.1
Moellney, M.2
Isermann, N.3
Wurzel, M.4
de Graaf, A.A.5
-
11
-
-
33845679072
-
Elementary metabolite units (EMU): A novel framework for modeling isotopic distributions
-
10.1016/j.ymben.2006.09.001, 1994654, 17088092
-
Antoniewicz MR, Kelleher JK, Stephanopoulos G. Elementary metabolite units (EMU): A novel framework for modeling isotopic distributions. Metab Eng 2007, 9:68-86. 10.1016/j.ymben.2006.09.001, 1994654, 17088092.
-
(2007)
Metab Eng
, vol.9
, pp. 68-86
-
-
Antoniewicz, M.R.1
Kelleher, J.K.2
Stephanopoulos, G.3
-
12
-
-
0343471424
-
Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices
-
10.1002/(SICI)1097-0290(19970920)55:6<831::AID-BIT2>3.0.CO;2-H, 18636594
-
Schmidt K, Carlsen M, Nielsen J, Villadsen J. Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices. Biotechnol Bioeng 1997, 55:831-840. 10.1002/(SICI)1097-0290(19970920)55:6<831::AID-BIT2>3.0.CO;2-H, 18636594.
-
(1997)
Biotechnol Bioeng
, vol.55
, pp. 831-840
-
-
Schmidt, K.1
Carlsen, M.2
Nielsen, J.3
Villadsen, J.4
-
13
-
-
78650554169
-
Central metabolic fluxes in the endosperm of developing maize seeds and their implications for metabolic engineering
-
10.1016/j.ymben.2010.10.002, 20969971
-
Alonso AP, Val DL, Shachar-Hill Y. Central metabolic fluxes in the endosperm of developing maize seeds and their implications for metabolic engineering. Metab Eng 2011, 13:96-107. 10.1016/j.ymben.2010.10.002, 20969971.
-
(2011)
Metab Eng
, vol.13
, pp. 96-107
-
-
Alonso, A.P.1
Val, D.L.2
Shachar-Hill, Y.3
-
14
-
-
15044347498
-
Metabolic-flux analysis of Saccharomyces cerevisiae CEN. PK113-7D based on mass isotopomer measurements of 13C-labeled primary metabolites
-
10.1016/j.femsyr.2004.10.007, 15780655
-
van Winden WA, van Dam JC, Ras C, Kleijn RJ, Vinke JL, van Gulik WM, Heijnen JJ. Metabolic-flux analysis of Saccharomyces cerevisiae CEN. PK113-7D based on mass isotopomer measurements of 13C-labeled primary metabolites. FEMS Yeast Res 2005, 5:559-568. 10.1016/j.femsyr.2004.10.007, 15780655.
-
(2005)
FEMS Yeast Res
, vol.5
, pp. 559-568
-
-
van Winden, W.A.1
van Dam, J.C.2
Ras, C.3
Kleijn, R.J.4
Vinke, J.L.5
van Gulik, W.M.6
Heijnen, J.J.7
-
15
-
-
17144387903
-
From stationary to instationary metabolic flux analysis
-
Wiechert W, Nöh K. From stationary to instationary metabolic flux analysis. Adv Biochem Eng Biotechnol 2005, 92:145-172.
-
(2005)
Adv Biochem Eng Biotechnol
, vol.92
, pp. 145-172
-
-
Wiechert, W.1
Nöh, K.2
-
16
-
-
33749448867
-
Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions
-
10.1016/j.ymben.2006.05.006, 16890470
-
Nöh K, Wahl A, Wiechert W. Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions. Metab Eng 2006, 8:554-577. 10.1016/j.ymben.2006.05.006, 16890470.
-
(2006)
Metab Eng
, vol.8
, pp. 554-577
-
-
Nöh, K.1
Wahl, A.2
Wiechert, W.3
-
17
-
-
79958703818
-
Stationary versus non-stationary (13)C-MFA: a comparison using a consistent dataset
-
10.1016/j.jbiotec.2010.07.008, 20638432
-
Noack S, Nöh K, Moch M, Oldiges M, Wiechert W. Stationary versus non-stationary (13)C-MFA: a comparison using a consistent dataset. J Biotechnol 2011, 154:179-190. 10.1016/j.jbiotec.2010.07.008, 20638432.
-
(2011)
J Biotechnol
, vol.154
, pp. 179-190
-
-
Noack, S.1
Nöh, K.2
Moch, M.3
Oldiges, M.4
Wiechert, W.5
-
18
-
-
41249094136
-
Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data
-
10.1002/bit.21675, 17972325
-
Schaub J, Mauch K, Reuss M. Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data. Biotechnol Bioeng 2008, 99:1170-1185. 10.1002/bit.21675, 17972325.
-
(2008)
Biotechnol Bioeng
, vol.99
, pp. 1170-1185
-
-
Schaub, J.1
Mauch, K.2
Reuss, M.3
-
19
-
-
34047177923
-
Metabolic flux analysis at ultra short time scale: Isotopically non-stationary 13C labeling experiments
-
10.1016/j.jbiotec.2006.11.015, 17207877
-
Nöh K, Grönke K, Luo B, Takors R, Oldiges M, Wiechert W. Metabolic flux analysis at ultra short time scale: Isotopically non-stationary 13C labeling experiments. J Biotechnol 2007, 129:249-267. 10.1016/j.jbiotec.2006.11.015, 17207877.
-
(2007)
J Biotechnol
, vol.129
, pp. 249-267
-
-
Nöh, K.1
Grönke, K.2
Luo, B.3
Takors, R.4
Oldiges, M.5
Wiechert, W.6
-
20
-
-
37349079028
-
A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum
-
10.1016/j.ymben.2007.07.001, 17905623
-
Nasution U, van Gulik WM, Ras C, Proell A, Heijnen JJ. A metabolome study of the steady-state relation between central metabolism, amino acid biosynthesis and penicillin production in Penicillium chrysogenum. Metab Eng 2008, 10:10-23. 10.1016/j.ymben.2007.07.001, 17905623.
-
(2008)
Metab Eng
, vol.10
, pp. 10-23
-
-
Nasution, U.1
van Gulik, W.M.2
Ras, C.3
Proell, A.4
Heijnen, J.J.5
-
21
-
-
44849135488
-
Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum
-
10.1016/j.ymben.2008.04.003, 18555197
-
Zhao Z, Kuijvenhoven K, Ras C, van Gulik WM, Heijnen JJ, Verheijen PJT, van Winden WA. Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum. Metab Eng 2008, 10:178-186. 10.1016/j.ymben.2008.04.003, 18555197.
-
(2008)
Metab Eng
, vol.10
, pp. 178-186
-
-
Zhao, Z.1
Kuijvenhoven, K.2
Ras, C.3
van Gulik, W.M.4
Heijnen, J.J.5
Verheijen, P.J.T.6
van Winden, W.A.7
-
22
-
-
0035819410
-
Energetics of growth and penicillin production in a high-producing strain of Penicillium chrysogenum
-
10.1002/1097-0290(20000120)72:2<185::AID-BIT7>3.0.CO;2-M, 11114656
-
van Gulik WM, Antoniewicz MR, de Laat WT, Vinke JL, Heijnen JJ. Energetics of growth and penicillin production in a high-producing strain of Penicillium chrysogenum. Biotechnol Bioeng 2001, 72:185-193. 10.1002/1097-0290(20000120)72:2<185::AID-BIT7>3.0.CO;2-M, 11114656.
-
(2001)
Biotechnol Bioeng
, vol.72
, pp. 185-193
-
-
van Gulik, W.M.1
Antoniewicz, M.R.2
de Laat, W.T.3
Vinke, J.L.4
Heijnen, J.J.5
-
23
-
-
0034691228
-
Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G
-
10.1002/(SICI)1097-0290(20000620)68:6<602::AID-BIT3>3.0.CO;2-2, 10799985
-
van Gulik WM, de Laat W, Vinke JL, Heijnen JJ. Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G. Biotechnol Bioeng 2000, 68:602-618. 10.1002/(SICI)1097-0290(20000620)68:6<602::AID-BIT3>3.0.CO;2-2, 10799985.
-
(2000)
Biotechnol Bioeng
, vol.68
, pp. 602-618
-
-
van Gulik, W.M.1
de Laat, W.2
Vinke, J.L.3
Heijnen, J.J.4
-
24
-
-
0006744051
-
Depolarization of plasma-membrane of Neurospora during active-transport of glucose - Evidence for a proton-dependent cotransport system
-
10.1073/pnas.71.5.1935, 388357, 4525303
-
Slayman CL, Slayman CW. Depolarization of plasma-membrane of Neurospora during active-transport of glucose - Evidence for a proton-dependent cotransport system. Proc Natl Acad Sci 1974, 71:1935-1939. 10.1073/pnas.71.5.1935, 388357, 4525303.
-
(1974)
Proc Natl Acad Sci
, vol.71
, pp. 1935-1939
-
-
Slayman, C.L.1
Slayman, C.W.2
-
25
-
-
0038691834
-
Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation
-
10.1002/bit.10648, 12740935
-
van Winden WA, van Gulik WM, Schipper D, Verheijen PJ, Krabben P, Vinke JL, Heijnen JJ. Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation. Biotechnol Bioeng 2003, 83:75-92. 10.1002/bit.10648, 12740935.
-
(2003)
Biotechnol Bioeng
, vol.83
, pp. 75-92
-
-
van Winden, W.A.1
van Gulik, W.M.2
Schipper, D.3
Verheijen, P.J.4
Krabben, P.5
Vinke, J.L.6
Heijnen, J.J.7
-
26
-
-
0031554628
-
Bidirectional Reaction Steps in Metabolic Networks: II. Flux Estimation and Statistical Analysis
-
10.1002/(SICI)1097-0290(19970705)55:1<118::AID-BIT13>3.0.CO;2-I, 18636450
-
Wiechert W, Siefke C, de Graaf AA, Marx A. Bidirectional Reaction Steps in Metabolic Networks: II. Flux Estimation and Statistical Analysis. Biotechnol Bioeng 1997, 55:118-135. 10.1002/(SICI)1097-0290(19970705)55:1<118::AID-BIT13>3.0.CO;2-I, 18636450.
-
(1997)
Biotechnol Bioeng
, vol.55
, pp. 118-135
-
-
Wiechert, W.1
Siefke, C.2
de Graaf, A.A.3
Marx, A.4
-
27
-
-
0030199054
-
Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies
-
10.1021/bp960022i, 8987472
-
Vanrolleghem PA, de Jong-Gubbels P, van Gulik WM, Pronk JT, van Dijken JP, Heijnen JJ. Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies. Biotechnol Prog 1996, 12:434-448. 10.1021/bp960022i, 8987472.
-
(1996)
Biotechnol Prog
, vol.12
, pp. 434-448
-
-
Vanrolleghem, P.A.1
de Jong-Gubbels, P.2
van Gulik, W.M.3
Pronk, J.T.4
van Dijken, J.P.5
Heijnen, J.J.6
-
28
-
-
0008589057
-
Uncertainties remain in the catabolism of valine
-
Wolf DA, Akers HA. Uncertainties remain in the catabolism of valine. Trends Biochem Sci 1986, 11:390-392.
-
(1986)
Trends Biochem Sci
, vol.11
, pp. 390-392
-
-
Wolf, D.A.1
Akers, H.A.2
-
29
-
-
0016207980
-
Production of 2-methylisocitric acid from N-paraffins by mutants of candida-lipolytica
-
Tabuchi T, Hara S. Production of 2-methylisocitric acid from N-paraffins by mutants of candida-lipolytica. Agric Biol Chem 1974, 38:1105-1106.
-
(1974)
Agric Biol Chem
, vol.38
, pp. 1105-1106
-
-
Tabuchi, T.1
Hara, S.2
-
30
-
-
53649092922
-
Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum
-
10.1038/nbt.1498, 18820685
-
Van Den Berg MA, Albang R, Albermann K, Badger JH, Daran J-M, Driessen AJM, Garcia-Estrada C, Fedorova ND, Harris DM, Heijne WHM, et al. Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum. Nat Biotechnol 2008, 26:1161-1168. 10.1038/nbt.1498, 18820685.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1161-1168
-
-
Van Den Berg, M.A.1
Albang, R.2
Albermann, K.3
Badger, J.H.4
Daran, J.-M.5
Driessen, A.J.M.6
Garcia-Estrada, C.7
Fedorova, N.D.8
Harris, D.M.9
Heijne, W.H.M.10
-
31
-
-
63649101650
-
Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells
-
10.1007/s10142-009-0110-6, 19156454
-
Kiel JAKW, Van Den Berg MA, Fusetti F, Poolman B, Bovenberg RAL, Veenhuis M, van der Klei IJ. Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells. Funct Integr Genomics 2009, 9:167-184. 10.1007/s10142-009-0110-6, 19156454.
-
(2009)
Funct Integr Genomics
, vol.9
, pp. 167-184
-
-
Kiel, J.A.K.W.1
Van Den Berg, M.A.2
Fusetti, F.3
Poolman, B.4
Bovenberg, R.A.L.5
Veenhuis, M.6
van der Klei, I.J.7
-
32
-
-
77956806246
-
Spatial and developmental differentiation of mannitol dehydrogenase and mannitol-1-phosphate dehydrogenase in Aspergillus niger
-
10.1128/EC.00363-09, 2937335, 20305000
-
Aguilar-Osorio G, Vankuyk PA, Seiboth B, Blom D, Solomon PS, Vinck A, Kindt F, Wösten HAB, de Vries RP. Spatial and developmental differentiation of mannitol dehydrogenase and mannitol-1-phosphate dehydrogenase in Aspergillus niger. Eukaryot Cell 2010, 9:1398-1402. 10.1128/EC.00363-09, 2937335, 20305000.
-
(2010)
Eukaryot Cell
, vol.9
, pp. 1398-1402
-
-
Aguilar-Osorio, G.1
Vankuyk, P.A.2
Seiboth, B.3
Blom, D.4
Solomon, P.S.5
Vinck, A.6
Kindt, F.7
Wösten, H.A.B.8
de Vries, R.P.9
-
33
-
-
79551545863
-
Single cell metabolomics
-
10.1016/j.copbio.2010.09.008, 20934866
-
Heinemann M, Zenobi R. Single cell metabolomics. Curr Opin Biotechnol 2011, 22:26-31. 10.1016/j.copbio.2010.09.008, 20934866.
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 26-31
-
-
Heinemann, M.1
Zenobi, R.2
-
34
-
-
79953227401
-
Subpopulation-specific metabolic pathway usage in mixed cultures as revealed by reporter protein-based 13C analysis
-
10.1128/AEM.02696-10, 3067264, 21216909
-
Rühl M, Hardt WD, Sauer U. Subpopulation-specific metabolic pathway usage in mixed cultures as revealed by reporter protein-based 13C analysis. Appl Environ Microbiol 2011, 77:1816-1821. 10.1128/AEM.02696-10, 3067264, 21216909.
-
(2011)
Appl Environ Microbiol
, vol.77
, pp. 1816-1821
-
-
Rühl, M.1
Hardt, W.D.2
Sauer, U.3
-
35
-
-
79958703818
-
Stationary versus non-stationary 13C-MFA: A comparison using a consistent dataset
-
Noack S, Nöh K, Moch M, Oldiges M, Wiechert W. Stationary versus non-stationary 13C-MFA: A comparison using a consistent dataset. J Biotechnol 2010, 154:1-12.
-
(2010)
J Biotechnol
, vol.154
, pp. 1-12
-
-
Noack, S.1
Nöh, K.2
Moch, M.3
Oldiges, M.4
Wiechert, W.5
-
36
-
-
33744455445
-
Experimental design principles for isotopically instationary 13C labeling experiments
-
10.1002/bit.20803, 16598793
-
Nöh K, Wiechert W. Experimental design principles for isotopically instationary 13C labeling experiments. Biotechnol Bioeng 2006, 94:234-251. 10.1002/bit.20803, 16598793.
-
(2006)
Biotechnol Bioeng
, vol.94
, pp. 234-251
-
-
Nöh, K.1
Wiechert, W.2
-
37
-
-
33646567520
-
Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum
-
10.1002/bit.20842, 16508996
-
Nasution U, van Gulik WM, Kleijn RJ, van Winden WA, Proell A, Heijnen JJ. Measurement of intracellular metabolites of primary metabolism and adenine nucleotides in chemostat cultivated Penicillium chrysogenum. Biotechnol Bioeng 2006, 94:159-166. 10.1002/bit.20842, 16508996.
-
(2006)
Biotechnol Bioeng
, vol.94
, pp. 159-166
-
-
Nasution, U.1
van Gulik, W.M.2
Kleijn, R.J.3
van Winden, W.A.4
Proell, A.5
Heijnen, J.J.6
-
38
-
-
1442326111
-
Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites
-
10.1002/bit.10907, 14966803, MIRACLE
-
Mashego MR, Wu L, van Dam JC, Ras C, Vinke JL, van Winden WA, van Gulik WM, Heijnen JJ: MIRACLE. mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites. Biotechnol Bioeng 2004, 85:620-628. 10.1002/bit.10907, 14966803.
-
(2004)
Biotechnol Bioeng
, vol.85
, pp. 620-628
-
-
Mashego, M.R.1
Wu, L.2
van Dam, J.C.3
Ras, C.4
Vinke, J.L.5
van Winden, W.A.6
van Gulik, W.M.7
Heijnen J.J8
-
39
-
-
11144324238
-
Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards
-
10.1016/j.ab.2004.09.001, 15620880
-
Wu L, Mashego MR, van Dam JC, Proell AM, Vinke JL, Ras C, van Winden WA, van Gulik WM, Heijnen JJ. Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards. Anal Biochem 2005, 336:164-171. 10.1016/j.ab.2004.09.001, 15620880.
-
(2005)
Anal Biochem
, vol.336
, pp. 164-171
-
-
Wu, L.1
Mashego, M.R.2
van Dam, J.C.3
Proell, A.M.4
Vinke, J.L.5
Ras, C.6
van Winden, W.A.7
van Gulik, W.M.8
Heijnen, J.J.9
-
40
-
-
69749110125
-
Quantitative evaluation of intracellular metabolite extraction techniques for yeast metabolomics
-
10.1021/ac900999t, 19653633
-
Canelas AB, ten Pierick A, Ras C, Seifar RM, van Dam JC, van Gulik WM, Heijnen JJ. Quantitative evaluation of intracellular metabolite extraction techniques for yeast metabolomics. Anal Chem 2009, 81:7379-7389. 10.1021/ac900999t, 19653633.
-
(2009)
Anal Chem
, vol.81
, pp. 7379-7389
-
-
Canelas, A.B.1
Ten Pierick, A.2
Ras, C.3
Seifar, R.M.4
van Dam, J.C.5
van Gulik, W.M.6
Heijnen, J.J.7
-
41
-
-
69749094421
-
A comprehensive method for the quantification of the non-oxidative pentose phosphate pathway intermediates in Saccharomyces cerevisiae by GC-IDMS
-
10.1016/j.jchromb.2009.07.019, 19647496
-
Cipollina C, ten Pierick A, Canelas AB, Seifar RM, van Maris AJ, van Dam JC, Heijnen JJ. A comprehensive method for the quantification of the non-oxidative pentose phosphate pathway intermediates in Saccharomyces cerevisiae by GC-IDMS. J Chromatogr B Analyt Technol Biomed Life Sci 2009, 877:3231-3236. 10.1016/j.jchromb.2009.07.019, 19647496.
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 3231-3236
-
-
Cipollina, C.1
Ten Pierick, A.2
Canelas, A.B.3
Seifar, R.M.4
van Maris, A.J.5
van Dam, J.C.6
Heijnen, J.J.7
-
42
-
-
0842343470
-
New tools for mass isotopomer data evaluation in 13C flux analysis: mass isotope correction, data consistency checking, and precursor relationships
-
10.1002/bit.10909, 14748080
-
Wahl SA, Dauner M, Wiechert W. New tools for mass isotopomer data evaluation in 13C flux analysis: mass isotope correction, data consistency checking, and precursor relationships. Biotechnol Bioeng 2004, 85:259-268. 10.1002/bit.10909, 14748080.
-
(2004)
Biotechnol Bioeng
, vol.85
, pp. 259-268
-
-
Wahl, S.A.1
Dauner, M.2
Wiechert, W.3
-
43
-
-
0026816530
-
Estimation of cell volume and biomass of Penicillium chrysogenum using image analysis
-
10.1002/bit.260390404, 18600959
-
Packer HL, Keshavarz-Moore E, Lilly MD, Thomas CR. Estimation of cell volume and biomass of Penicillium chrysogenum using image analysis. Biotechnol Bioeng 1992, 39:384-391. 10.1002/bit.260390404, 18600959.
-
(1992)
Biotechnol Bioeng
, vol.39
, pp. 384-391
-
-
Packer, H.L.1
Keshavarz-Moore, E.2
Lilly, M.D.3
Thomas, C.R.4
-
44
-
-
61349165717
-
Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production
-
10.1186/1471-2164-10-75, 2657799, 19203396
-
Harris DM, van der Krogt ZA, Klaassen P, Raamsdonk LM, Hage S, Van Den Berg MA, Bovenberg RAL, Pronk JT, Daran J-M. Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production. BMC Genomics 2009, 10:75. 10.1186/1471-2164-10-75, 2657799, 19203396.
-
(2009)
BMC Genomics
, vol.10
, pp. 75
-
-
Harris, D.M.1
van der Krogt, Z.A.2
Klaassen, P.3
Raamsdonk, L.M.4
Hage, S.5
Van Den Berg, M.A.6
Bovenberg, R.A.L.7
Pronk, J.T.8
Daran, J.-M.9
-
45
-
-
33644821680
-
Enzymic analysis of NADPH metabolism in b-lactam-producing Penicillium chrysogenum: presence of a mitochondrial NADPH dehydrogenase
-
10.1016/j.ymben.2005.09.004, 16253533
-
Harris DM, Diderich JA, van der Krogt ZA, Luttik MAH, Raamsdonk LM, Bovenberg RAL, van Gulik WM, van Dijken JP, Pronk JT. Enzymic analysis of NADPH metabolism in b-lactam-producing Penicillium chrysogenum: presence of a mitochondrial NADPH dehydrogenase. Metab Eng 2006, 8:91-101. 10.1016/j.ymben.2005.09.004, 16253533.
-
(2006)
Metab Eng
, vol.8
, pp. 91-101
-
-
Harris, D.M.1
Diderich, J.A.2
van der Krogt, Z.A.3
Luttik, M.A.H.4
Raamsdonk, L.M.5
Bovenberg, R.A.L.6
van Gulik, W.M.7
van Dijken, J.P.8
Pronk, J.T.9
-
46
-
-
0034741985
-
A universal framework for 13C metabolic flux analysis
-
Wiechert W, Möllney M, Petersen S, de Graaf AA. A universal framework for 13C metabolic flux analysis. Metab Eng 2001, 3:256-283.
-
(2001)
Metab Eng
, vol.3
, pp. 256-283
-
-
Wiechert, W.1
Möllney, M.2
Petersen, S.3
de Graaf, A.A.4
-
47
-
-
84872182505
-
GPROMS Model Builder (v3.5.0)
-
London: United Kingdom Process Systems Enterprise Limited
-
Limited PSE. gPROMS Model Builder (v3.5.0). Optimisation Guide 2011, London: United Kingdom Process Systems Enterprise Limited.
-
(2011)
Optimisation Guide
-
-
Limited, P.S.E.1
-
48
-
-
0029278153
-
Metabolic flux distributions in Penicillium chrysogenum during fed-batch cultivations
-
10.1002/bit.260460205, 18623271
-
Jørgensen H, Nielsen J, Villadsen J, Møllgaard H. Metabolic flux distributions in Penicillium chrysogenum during fed-batch cultivations. Biotechnol Bioeng 1995, 46:117-131. 10.1002/bit.260460205, 18623271.
-
(1995)
Biotechnol Bioeng
, vol.46
, pp. 117-131
-
-
Jørgensen, H.1
Nielsen, J.2
Villadsen, J.3
Møllgaard, H.4
-
49
-
-
0034691298
-
Metabolic network analysis of Penicillium chrysogenum using 13C-labeled glucose
-
10.1002/(SICI)1097-0290(20000620)68:6<652::AID-BIT8>3.0.CO;2-J, 10799990
-
Christensen B, Nielsen J. Metabolic network analysis of Penicillium chrysogenum using 13C-labeled glucose. Biotechnol Bioeng 2000, 68:652-659. 10.1002/(SICI)1097-0290(20000620)68:6<652::AID-BIT8>3.0.CO;2-J, 10799990.
-
(2000)
Biotechnol Bioeng
, vol.68
, pp. 652-659
-
-
Christensen, B.1
Nielsen, J.2
-
50
-
-
34347355487
-
Evidence, through 13C-labelling analysis, of phosphoketolase activity in fungi
-
Thykaer J, Nielsen J. Evidence, through 13C-labelling analysis, of phosphoketolase activity in fungi. Process Biochem 2007, 42:1050-1055.
-
(2007)
Process Biochem
, vol.42
, pp. 1050-1055
-
-
Thykaer, J.1
Nielsen, J.2
-
51
-
-
1842473645
-
Impact of transamination reactions and protein turnover on labeling dynamics in 13C-labeling experiments
-
10.1002/bit.20036, 15052641
-
Grotkjaer T, Akesson M, Christensen B, Gombert AK, Nielsen J. Impact of transamination reactions and protein turnover on labeling dynamics in 13C-labeling experiments. Biotechnol Bioeng 2004, 86:209-216. 10.1002/bit.20036, 15052641.
-
(2004)
Biotechnol Bioeng
, vol.86
, pp. 209-216
-
-
Grotkjaer, T.1
Akesson, M.2
Christensen, B.3
Gombert, A.K.4
Nielsen, J.5
-
52
-
-
76849112730
-
Study of stationary phase metabolism via isotopomer analysis of amino acids from an isolated protein
-
Shaikh AS, Tang YJ, Mukhopadhyay A, Martin HG, Gin J, Benke PI, Keasling JD. Study of stationary phase metabolism via isotopomer analysis of amino acids from an isolated protein. Biotechnol Prog 2010, 26:52-56.
-
(2010)
Biotechnol Prog
, vol.26
, pp. 52-56
-
-
Shaikh, A.S.1
Tang, Y.J.2
Mukhopadhyay, A.3
Martin, H.G.4
Gin, J.5
Benke, P.I.6
Keasling, J.D.7
-
53
-
-
59149092918
-
Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate
-
10.1111/j.1567-1364.2008.00465.x, 19220865
-
Aboka FO, Heijnen JJ, van Winden WA. Dynamic 13C-tracer study of storage carbohydrate pools in aerobic glucose-limited Saccharomyces cerevisiae confirms a rapid steady-state turnover and fast mobilization during a modest stepup in the glucose uptake rate. FEMS Yeast Res 2009, 9:191-201. 10.1111/j.1567-1364.2008.00465.x, 19220865.
-
(2009)
FEMS Yeast Res
, vol.9
, pp. 191-201
-
-
Aboka, F.O.1
Heijnen, J.J.2
van Winden, W.A.3
-
54
-
-
77950630496
-
From fluxes and isotope labeling patterns towards in silico cells
-
10.1016/j.copbio.2010.01.014, 20185292
-
Dauner M. From fluxes and isotope labeling patterns towards in silico cells. Curr Opin Biotechnol 2010, 21:55-62. 10.1016/j.copbio.2010.01.014, 20185292.
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 55-62
-
-
Dauner, M.1
-
55
-
-
77950628238
-
Metabolic flux analysis in eukaryotes
-
10.1016/j.copbio.2010.01.011, 20163950
-
Niklas J, Schneider K, Heinzle E. Metabolic flux analysis in eukaryotes. Curr Opin Biotechnol 2010, 21:63-69. 10.1016/j.copbio.2010.01.011, 20163950.
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 63-69
-
-
Niklas, J.1
Schneider, K.2
Heinzle, E.3
-
56
-
-
65549087156
-
Advances in analysis of microbial metabolic fluxes via 13C isotopic labeling
-
10.1002/mas.20191, 19025966
-
Tang YJ, Martin HG, Myers S, Rodriguez S, Baidoo EE, Keasling JD. Advances in analysis of microbial metabolic fluxes via 13C isotopic labeling. Mass Spectrom Rev 2009, 28:362-375. 10.1002/mas.20191, 19025966.
-
(2009)
Mass Spectrom Rev
, vol.28
, pp. 362-375
-
-
Tang, Y.J.1
Martin, H.G.2
Myers, S.3
Rodriguez, S.4
Baidoo, E.E.5
Keasling, J.D.6
-
57
-
-
84979315537
-
Sugar alcohols (polyols) in fungi and green plants
-
Lewis DH, Smith DC. Sugar alcohols (polyols) in fungi and green plants. New Phytol 1967, 66:143-184.
-
(1967)
New Phytol
, vol.66
, pp. 143-184
-
-
Lewis, D.H.1
Smith, D.C.2
-
58
-
-
34249776327
-
Decoding the mannitol enigma in filamentous fungi
-
10.1016/j.tim.2007.04.002, 17442575
-
Solomon PS, Waters ODC, Oliver RP. Decoding the mannitol enigma in filamentous fungi. Trends Microbiol 2007, 15:257-262. 10.1016/j.tim.2007.04.002, 17442575.
-
(2007)
Trends Microbiol
, vol.15
, pp. 257-262
-
-
Solomon, P.S.1
Waters, O.D.C.2
Oliver, R.P.3
-
59
-
-
15044352160
-
Acid trehalase in yeasts and filamentous fungi: Localization, regulation and physiological function
-
10.1016/j.femsyr.2005.01.002, 15780651
-
Parrou JL, Jules M, Beltran G, Francois J. Acid trehalase in yeasts and filamentous fungi: Localization, regulation and physiological function. FEMS Yeast Res 2005, 5:503-511. 10.1016/j.femsyr.2005.01.002, 15780651.
-
(2005)
FEMS Yeast Res
, vol.5
, pp. 503-511
-
-
Parrou, J.L.1
Jules, M.2
Beltran, G.3
Francois, J.4
-
60
-
-
70349229608
-
The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function
-
10.1111/j.1742-4658.2009.07227.x, 19703229
-
He S, Bystricky K, Leon S, Francois JM, Parrou JL. The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function. FEBS J 2009, 276:5432-5446. 10.1111/j.1742-4658.2009.07227.x, 19703229.
-
(2009)
FEBS J
, vol.276
, pp. 5432-5446
-
-
He, S.1
Bystricky, K.2
Leon, S.3
Francois, J.M.4
Parrou, J.L.5
-
61
-
-
79960342167
-
Visualizing multi-omics data in metabolic networks with the software Omix: A case study
-
10.1016/j.biosystems.2011.04.003, 21575673
-
Droste P, Miebach S, Niedenführ S, Wiechert W, Nöh K. Visualizing multi-omics data in metabolic networks with the software Omix: A case study. Biosystems 2011, 105:154-161. 10.1016/j.biosystems.2011.04.003, 21575673.
-
(2011)
Biosystems
, vol.105
, pp. 154-161
-
-
Droste, P.1
Miebach, S.2
Niedenführ, S.3
Wiechert, W.4
Nöh, K.5
-
62
-
-
2442665707
-
Two distinct pathways for trehalose assimilation in the yeast Saccharomyces cerevisiae
-
10.1128/AEM.70.5.2771-2778.2004, 404389, 15128531
-
Jules M, Guillou V, Francois J, Parrou JL. Two distinct pathways for trehalose assimilation in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 2004, 70:2771-2778. 10.1128/AEM.70.5.2771-2778.2004, 404389, 15128531.
-
(2004)
Appl Environ Microbiol
, vol.70
, pp. 2771-2778
-
-
Jules, M.1
Guillou, V.2
Francois, J.3
Parrou, J.L.4
|