Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation

Biotechnology and Bioengineering

Volumn 83, Issue 1, 2003, Pages 75-92

  Van Winden, Wouter A ^a,c   Van Gulik, Walter M ^a   Schipper, Dick ^b   Verheijen, Peter J T ^a   Krabben, Preben ^a   Vinke, Jacobus L ^a   Heijnen, Joseph J ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b DSM RESEARCH   (Netherlands)

^c KLUYVER CENTRE FOR GENOMICS OF INDUSTRIAL FERMENTATION   (Netherlands)

Author keywords

13C labeling; Bondomer; Metabolic flux analysis; Metabolic network analysis; NMR; Penicillium chrysogenum

Indexed keywords

AMMONIA; COMPUTER SIMULATION; ENZYMES; ERROR ANALYSIS; METABOLITES; PHOSPHATES;

METABOLIC FLUX;

METABOLISM;

AMMONIA; DIHYDROXYACETONE KINASE; FRUCTOSE 6 PHOSPHATE; FRUCTOSE 6 PHOSPHATE ALDOLASE; NITRATE; PHOSPHOTRANSFERASE; TRANSALDOLASE; TRANSKETOLASE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ENZYME MECHANISM; GLYCOLYSIS; NONHUMAN; PENICILLIUM CHRYSOGENUM; PENTOSE PHOSPHATE CYCLE; PROTON NUCLEAR MAGNETIC RESONANCE;

AMMONIA; BIOREACTORS; CARBON; CARBON ISOTOPES; COMPUTER SIMULATION; GLYCOLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; NITRATES; PENICILLIUM CHRYSOGENUM; PENTOSE PHOSPHATE PATHWAY; PROTONS;

PENICILLIUM; PENICILLIUM CHRYSOGENUM;

EID: 0038691834     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10648     Document Type: Article

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