Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells. Palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/AKT stimulation and glucose uptake

European Journal of Biochemistry

Volumn 266, Issue 1, 1999, Pages 17-25

  Storz, Peter ^b   Döppler, Heike ^b   Wernig, Anton ^b   Pfizenmaier, Klaus ^b   Müller, Gertraud ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b NONE

Author keywords

Glucose transport; Insulin resistance; Nonesterified fatty acids; Skeletal muscle cells; Tumour necrosis factor (TNF)

Indexed keywords

DEOXYGLUCOSE; FATTY ACID; GLUCOSE TRANSPORTER; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT TUMOR NECROSIS FACTOR;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; INSULIN RESISTANCE; MALE; MOUSE; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELLS, CULTURED; DEOXYGLUCOSE; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; FATTY ACIDS, NONESTERIFIED; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROSOMES; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYRISTIC ACID; OBESITY; PALMITIC ACID; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0002697987     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00809.x     Document Type: Article

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