Ascofuranone prevents ER stress-induced insulin resistance via activation of AMP-activated protein kinase in L6 myotube cells

Biochemical and Biophysical Research Communications

Volumn 396, Issue 4, 2010, Pages 967-972

  Hwang, Seung Lark ^a,b   Chang, Hyeun Wook ^b   Lee, In Kyu ^c   Yang, Byung Keun ^d   Magae, Junji ^e   Chang, Young Chae ^a  

^a The Catholic University of Korea   (South Korea)

^b Yeungnam University   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d Heuksalim Soil Research Institute   (South Korea)

^e CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

Author keywords

AMP activated protein kinase (AMPK); Ascofuranone; Glucose uptake; Insulin resistance

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ANTIFUNGAL AGENT; ASCOFURANONE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PROTEIN KINASE INHIBITOR; SERINE; THREONINE; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INSULIN RESISTANCE; MYOTUBE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIFUNGAL AGENTS; CELL LINE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GLUCOSE; HUMANS; INSULIN; INSULIN ANTAGONISTS; INSULIN RESISTANCE; MUSCLE FIBERS, SKELETAL; RATS; SESQUITERPENES; STRESS, PHYSIOLOGICAL;

ASCOCHYTA; FUNGI;

EID: 77953291946     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.034     Document Type: Article

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