Ouabain targets the unfolded protein response for selective killing of HepG2 cells during glucose deprivation

Cancer Biotherapy and Radiopharmaceuticals

Volumn 27, Issue 8, 2012, Pages 457-463

  Ozdemir, Tulay ^a   Nar, Rukiye ^b   Kilinc, Veli ^c   Alacam, Hasan ^c   Salis, Osman ^c   Duzgun, Aynur ^d   Gulten, Sedat ^c   Bedir, Abdulkerim ^c  

^a Gazi State Hospital Samsun   (Turkey)

^b Aksaray State Hospital   (Turkey)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^d Tirebolu State Hospital   (Turkey)

Author keywords

2 deoxyglucose; CHOP; Grp78; HepG2; ouabain; unfolded protein response

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; OUABAIN;

APOPTOSIS; ARTICLE; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL VIABILITY; CHOP GENE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; GENE; GENE EXPRESSION; GLUCOSE REGULATED PROTEIN 78 GENE; GLUCOSE REGULATED PROTEIN 94 GENE; HEME OXYGENASE 1 GENE; HEXOKINASE II GENE; HUMAN; HUMAN CELL; MRP 1 GENE; MULTIDRUG RESISTANT GENE 1; PRIORITY JOURNAL; PROSTATE APOPTOSIS RESPONSE 4 GENE; REAL TIME POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ANIMALS; APOPTOSIS; CELL GROWTH PROCESSES; DEOXYGLUCOSE; GENE EXPRESSION; GLUCOSE; HEAT-SHOCK PROTEINS; HEME OXYGENASE-1; HEP G2 CELLS; HSP40 HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; NEOPLASM PROTEINS; OUABAIN; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84867537389     PISSN: 10849785     EISSN: 15578852     Source Type: Journal    
DOI: 10.1089/cbr.2011.1138     Document Type: Article

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