Targeting the Na+/K+-ATPase α1 subunit of hepatoma HepG2 cell line to induce apoptosis and cell cycle arresting

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 5, 2010, Pages 743-751

  Xu, Zhong Wei ^a,c   Wang, Feng Mei ^b   Gao, Mo Jie ^c   Chen, Xiao Yi ^c   Hu, Wen Liang ^a   Xu, Rui Cheng ^a  

^a Tianjin Key Laboratory for Biomarkers of Occupational and Environmental Hazard   (China)

^b Tianjin 3rd Central Hospital   (China)

^c MEDICAL COLLEGE OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Cell cycle; HepG2 cell; Na+ K+ ATPase; Ouabain; Proliferation; Small interfering ribonucleic acid

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA1; CALCIUM ION; CYCLIN A1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; MESSENGER RNA; OUABAIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRUCTURE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL CARCINOMA; MOLECULAR MECHANICS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CALCIUM; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN A1; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; HEP G2 CELLS; HUMANS; LIVER; LIVER NEOPLASMS; OUABAIN; PHYTOTHERAPY; PLANT EXTRACTS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; S PHASE; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 77952327427     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.743     Document Type: Article

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