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Volumn 80, Issue 23, 2007, Pages 2093-2107

The digitalis-like steroid hormones: New mechanisms of action and biological significance

Author keywords

Digitalis; K+ ATPase; Na+; Natriuretic hormone; Ouabain; Steroids

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; CARDIAC GLYCOSIDE; DIGITALIS; STEROID HORMONE;

EID: 34248570330     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.03.013     Document Type: Review
Times cited : (141)

References (205)
  • 1
    • 0347625839 scopus 로고    scopus 로고
    • Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5
    • Abramowitz J., Dai C., Hirschi K.K., Dmitrieva R.I., Doris P.A., Liu L., and Allen J.C. Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5. Circulation 108 24 (2003) 3048-3053
    • (2003) Circulation , vol.108 , Issue.24 , pp. 3048-3053
    • Abramowitz, J.1    Dai, C.2    Hirschi, K.K.3    Dmitrieva, R.I.4    Doris, P.A.5    Liu, L.6    Allen, J.C.7
  • 7
    • 0035824551 scopus 로고    scopus 로고
    • Ouabain-induced signaling and vascular smooth muscle cell proliferation
    • Aydemir-Koksoy A., Abramowitz J., and Allen J.C. Ouabain-induced signaling and vascular smooth muscle cell proliferation. The Journal of Biological Chemistry 276 49 (2001) 46605-46611
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.49 , pp. 46605-46611
    • Aydemir-Koksoy, A.1    Abramowitz, J.2    Allen, J.C.3
  • 8
    • 21344446365 scopus 로고    scopus 로고
    • Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension
    • Bagrov A.Y., and Fedorova O.V. Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension. Frontiers in Bioscience 10 (2005) 2250-2256
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2250-2256
    • Bagrov, A.Y.1    Fedorova, O.V.2
  • 10
    • 21344453315 scopus 로고    scopus 로고
    • Endogenous digitalis-like ligands and Na/K-ATPase inhibition in experimental diabetes mellitus
    • Bagrov Y.Y., Manusova N.B., Egorova I.A., Fedorova O.V., and Bagrov A.Y. Endogenous digitalis-like ligands and Na/K-ATPase inhibition in experimental diabetes mellitus. Frontiers in Bioscience 10 (2005) 2257-2262
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2257-2262
    • Bagrov, Y.Y.1    Manusova, N.B.2    Egorova, I.A.3    Fedorova, O.V.4    Bagrov, A.Y.5
  • 11
    • 0017340805 scopus 로고
    • Oncogenic transformation of chick-embryo fibroblasts by Rous sarcoma virus alters rubidium uptake and ouabain binding
    • Banerjee S.P., Bosmann H.B., and Morgan H.R. Oncogenic transformation of chick-embryo fibroblasts by Rous sarcoma virus alters rubidium uptake and ouabain binding. Experimental Cell Research 104 1 (1977) 111-117
    • (1977) Experimental Cell Research , vol.104 , Issue.1 , pp. 111-117
    • Banerjee, S.P.1    Bosmann, H.B.2    Morgan, H.R.3
  • 12
    • 20944451171 scopus 로고    scopus 로고
    • Ouabain-like compound changes rapidly on physical exercise in humans and dogs: effects of beta-blockade and angiotensin-converting enzyme inhibition
    • Bauer N., Muller-Ehmsen J., Kramer U., Hambarchian N., Zobel C., Schwinger R.H., Neu H., Kirch U., Grunbaum E.G., and Schoner W. Ouabain-like compound changes rapidly on physical exercise in humans and dogs: effects of beta-blockade and angiotensin-converting enzyme inhibition. Hypertension 45 5 (2005) 1024-1028
    • (2005) Hypertension , vol.45 , Issue.5 , pp. 1024-1028
    • Bauer, N.1    Muller-Ehmsen, J.2    Kramer, U.3    Hambarchian, N.4    Zobel, C.5    Schwinger, R.H.6    Neu, H.7    Kirch, U.8    Grunbaum, E.G.9    Schoner, W.10
  • 13
    • 0039438642 scopus 로고    scopus 로고
    • The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function
    • Beguin P., Wang X., Firsov D., Puoti A., Claeys D., Horisberger J.D., and Geering K. The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function. The EMBO Journal 16 14 (1997) 4250-4260
    • (1997) The EMBO Journal , vol.16 , Issue.14 , pp. 4250-4260
    • Beguin, P.1    Wang, X.2    Firsov, D.3    Puoti, A.4    Claeys, D.5    Horisberger, J.D.6    Geering, K.7
  • 14
    • 0031758268 scopus 로고    scopus 로고
    • Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function
    • Blanco G., and Mercer R.W. Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function. The American Journal of Physiology 275 5 Pt 2 (1998) F633-F650
    • (1998) The American Journal of Physiology , vol.275 , Issue.5 PART 2
    • Blanco, G.1    Mercer, R.W.2
  • 16
    • 33745047712 scopus 로고    scopus 로고
    • Calcium sensing receptors and calcium oscillations: calcium as a first messenger
    • Breitwieser G.E. Calcium sensing receptors and calcium oscillations: calcium as a first messenger. Current Topics in Developmental Biology 73 (2006) 85-114
    • (2006) Current Topics in Developmental Biology , vol.73 , pp. 85-114
    • Breitwieser, G.E.1
  • 17
    • 21344431898 scopus 로고    scopus 로고
    • Endogenous digitalis-like factors. An historical overview
    • Buckalew V.M. Endogenous digitalis-like factors. An historical overview. Frontiers in Bioscience 10 (2005) 2325-2334
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2325-2334
    • Buckalew, V.M.1
  • 18
    • 0031900223 scopus 로고    scopus 로고
    • Brain "ouabain", a neurosteroid, mediates sympathetic hyperactivity in salt-sensitive hypertension
    • Budzikowski A.S., Huang B.S., and Leenen F.H. Brain "ouabain", a neurosteroid, mediates sympathetic hyperactivity in salt-sensitive hypertension. Clinical and Experimental Hypertension 20 2 (1998) 119-140
    • (1998) Clinical and Experimental Hypertension , vol.20 , Issue.2 , pp. 119-140
    • Budzikowski, A.S.1    Huang, B.S.2    Leenen, F.H.3
  • 21
    • 0029137474 scopus 로고
    • Functional significance of the beta-subunit for heterodimeric P-type ATPases
    • Chow D.C., and Forte J.G. Functional significance of the beta-subunit for heterodimeric P-type ATPases. The Journal of Experimental Biology 198 Pt 1 (1995) 1-17
    • (1995) The Journal of Experimental Biology , vol.198 , Issue.PART 1 , pp. 1-17
    • Chow, D.C.1    Forte, J.G.2
  • 22
    • 0027485227 scopus 로고
    • Possible role of endogenous ouabain-like compounds in the pathophysiology of bipolar illness
    • Christo P.J., and el-Mallakh R.S. Possible role of endogenous ouabain-like compounds in the pathophysiology of bipolar illness. Medical Hypotheses 41 4 (1993) 378-383
    • (1993) Medical Hypotheses , vol.41 , Issue.4 , pp. 378-383
    • Christo, P.J.1    el-Mallakh, R.S.2
  • 24
    • 0034977171 scopus 로고    scopus 로고
    • Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells
    • Chueh S.C., Guh J.H., Chen J., Lai M.K., and Teng C.M. Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells. The Journal of Urology 166 1 (2001) 347-353
    • (2001) The Journal of Urology , vol.166 , Issue.1 , pp. 347-353
    • Chueh, S.C.1    Guh, J.H.2    Chen, J.3    Lai, M.K.4    Teng, C.M.5
  • 25
    • 0030977127 scopus 로고    scopus 로고
    • Subunit interactions in the Na,K-ATPase explored with the yeast two-hybrid system
    • Colonna T.E., Huynh L., and Fambrough D.M. Subunit interactions in the Na,K-ATPase explored with the yeast two-hybrid system. The Journal of Biological Chemistry 272 19 (1997) 12366-12372
    • (1997) The Journal of Biological Chemistry , vol.272 , Issue.19 , pp. 12366-12372
    • Colonna, T.E.1    Huynh, L.2    Fambrough, D.M.3
  • 30
    • 0242495693 scopus 로고    scopus 로고
    • Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives
    • Daniel D., Susal C., Kopp B., Opelz G., and Terness P. Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives. International Immunopharmacology 3 13-14 (2003) 1791-1801
    • (2003) International Immunopharmacology , vol.3 , Issue.13-14 , pp. 1791-1801
    • Daniel, D.1    Susal, C.2    Kopp, B.3    Opelz, G.4    Terness, P.5
  • 33
    • 0034784818 scopus 로고    scopus 로고
    • The hypothalamus and hypertension
    • De Wardener H.E. The hypothalamus and hypertension. Physiological Reviews 81 4 (2001) 1599-1658
    • (2001) Physiological Reviews , vol.81 , Issue.4 , pp. 1599-1658
    • De Wardener, H.E.1
  • 34
    • 4544321868 scopus 로고    scopus 로고
    • Expression, regulation and function of Na,K-ATPase in the lens
    • Delamere N.A., and Tamiya S. Expression, regulation and function of Na,K-ATPase in the lens. Progress in Retinal and Eye Research 23 6 (2004) 593-615
    • (2004) Progress in Retinal and Eye Research , vol.23 , Issue.6 , pp. 593-615
    • Delamere, N.A.1    Tamiya, S.2
  • 36
    • 0041344556 scopus 로고    scopus 로고
    • Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells
    • Dmitrieva R.I., and Doris P.A. Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells. The Journal of Biological Chemistry 278 30 (2003) 28160-28166
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.30 , pp. 28160-28166
    • Dmitrieva, R.I.1    Doris, P.A.2
  • 37
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch R.E., Xu K., and Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392 6679 (1998) 933-936
    • (1998) Nature , vol.392 , Issue.6679 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 38
    • 34248579880 scopus 로고    scopus 로고
    • Endocrine hypertension
    • Greenspan F.C., and Gardner D.G. (Eds), Lange Medical Books/McGraw-Hill, NY
    • Don B., Schambelan M., and Lo J.C. Endocrine hypertension. In: Greenspan F.C., and Gardner D.G. (Eds). Endocrine Hypertension (2004), Lange Medical Books/McGraw-Hill, NY 100-120
    • (2004) Endocrine Hypertension , pp. 100-120
    • Don, B.1    Schambelan, M.2    Lo, J.C.3
  • 40
    • 0028222079 scopus 로고
    • Is ouabain an authentic endogenous mammalian substance derived from the adrenal?
    • Doris P.A., Jenkins L.A., and Stocco D.M. Is ouabain an authentic endogenous mammalian substance derived from the adrenal?. Hypertension 23 5 (1994) 632-638
    • (1994) Hypertension , vol.23 , Issue.5 , pp. 632-638
    • Doris, P.A.1    Jenkins, L.A.2    Stocco, D.M.3
  • 49
    • 0037022951 scopus 로고    scopus 로고
    • Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride-dependent hypertension
    • Fedorova O.V., Talan M.I., Agalakova N.I., Lakatta E.G., and Bagrov A.Y. Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride-dependent hypertension. Circulation 105 9 (2002) 1122-1127
    • (2002) Circulation , vol.105 , Issue.9 , pp. 1122-1127
    • Fedorova, O.V.1    Talan, M.I.2    Agalakova, N.I.3    Lakatta, E.G.4    Bagrov, A.Y.5
  • 51
    • 0035133295 scopus 로고    scopus 로고
    • Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control
    • Feraille E., and Doucet A. Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control. Physiological Reviews 81 1 (2001) 345-418
    • (2001) Physiological Reviews , vol.81 , Issue.1 , pp. 345-418
    • Feraille, E.1    Doucet, A.2
  • 53
    • 21344466110 scopus 로고    scopus 로고
    • The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications
    • Ferrandi M., Manunta P., Ferrari P., and Bianchi G. The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications. Frontiers in Bioscience 10 (2005) 2472-2477
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2472-2477
    • Ferrandi, M.1    Manunta, P.2    Ferrari, P.3    Bianchi, G.4
  • 55
    • 0033559235 scopus 로고    scopus 로고
    • +-ATPase from mammalian kidneys and Xenopus oocytes by cGMP-dependent protein kinase results in stimulation of ATPase activity
    • +-ATPase from mammalian kidneys and Xenopus oocytes by cGMP-dependent protein kinase results in stimulation of ATPase activity. European Journal of Biochemistry/FEBS 260 3 (1999) 904-910
    • (1999) European Journal of Biochemistry/FEBS , vol.260 , Issue.3 , pp. 904-910
    • Fotis, H.1    Tatjanenko, L.V.2    Vasilets, L.A.3
  • 56
    • 33744974783 scopus 로고    scopus 로고
    • Mechanisms of calcium signaling and function in lymphocytes
    • Freedman B.D. Mechanisms of calcium signaling and function in lymphocytes. Critical Reviews in Immunology 26 2 (2006) 97-111
    • (2006) Critical Reviews in Immunology , vol.26 , Issue.2 , pp. 97-111
    • Freedman, B.D.1
  • 57
    • 33745228422 scopus 로고    scopus 로고
    • Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5
    • Frese S., Frese-Schaper M., Andres A.C., Miescher D., Zumkehr B., and Schmid R.A. Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5. Cancer Research 66 11 (2006) 5867-5874
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5867-5874
    • Frese, S.1    Frese-Schaper, M.2    Andres, A.C.3    Miescher, D.4    Zumkehr, B.5    Schmid, R.A.6
  • 58
    • 0036591601 scopus 로고    scopus 로고
    • Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity
    • Fridman A.I., Matveev S.A., Agalakova N.I., Fedorova O.V., Lakatta E.G., and Bagrov A.Y. Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity. Journal of Hypertension 20 6 (2002) 1189-1194
    • (2002) Journal of Hypertension , vol.20 , Issue.6 , pp. 1189-1194
    • Fridman, A.I.1    Matveev, S.A.2    Agalakova, N.I.3    Fedorova, O.V.4    Lakatta, E.G.5    Bagrov, A.Y.6
  • 63
    • 0031595362 scopus 로고    scopus 로고
    • Simultaneous measurement of marinobufagenin, ouabain, and hypertension-associated protein in various disease states
    • Gonick H.C., Ding Y., Vaziri N.D., Bagrov A.Y., and Fedorova O.V. Simultaneous measurement of marinobufagenin, ouabain, and hypertension-associated protein in various disease states. Clinical and Experimental Hypertension 20 5-6 (1998) 617-627
    • (1998) Clinical and Experimental Hypertension , vol.20 , Issue.5-6 , pp. 617-627
    • Gonick, H.C.1    Ding, Y.2    Vaziri, N.D.3    Bagrov, A.Y.4    Fedorova, O.V.5
  • 65
    • 0025064705 scopus 로고
    • Digitalis-like activity in human plasma: relation to blood pressure and sodium balance
    • Goto A., Yamada K., Ishii M., and Sugimoto T. Digitalis-like activity in human plasma: relation to blood pressure and sodium balance. The American Journal of Medicine 89 4 (1990) 420-426
    • (1990) The American Journal of Medicine , vol.89 , Issue.4 , pp. 420-426
    • Goto, A.1    Yamada, K.2    Ishii, M.3    Sugimoto, T.4
  • 66
    • 0032792122 scopus 로고    scopus 로고
    • Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls
    • Grider G., El-Mallakh R.S., Huff M.O., Buss T.J., Miller J., and Valdes Jr. R. Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls. Journal of Affective Disorders 54 3 (1999) 261-267
    • (1999) Journal of Affective Disorders , vol.54 , Issue.3 , pp. 261-267
    • Grider, G.1    El-Mallakh, R.S.2    Huff, M.O.3    Buss, T.J.4    Miller, J.5    Valdes Jr., R.6
  • 67
  • 70
    • 0037166251 scopus 로고    scopus 로고
    • +-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases
    • +-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases. The Journal of Biological Chemistry 277 21 (2002) 18694-18702
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.21 , pp. 18694-18702
    • Haas, M.1    Wang, H.2    Tian, J.3    Xie, Z.4
  • 71
    • 0017188515 scopus 로고
    • The role of humoral agents in volume expanded hypertension
    • Haddy F.J., and Overbeck H.W. The role of humoral agents in volume expanded hypertension. Life Sciences 19 7 (1976) 935-947
    • (1976) Life Sciences , vol.19 , Issue.7 , pp. 935-947
    • Haddy, F.J.1    Overbeck, H.W.2
  • 73
    • 1542290103 scopus 로고    scopus 로고
    • Biosynthesis of endogenous cardiac glycosides by mammalian adrenocortical cells: three steps forward
    • Hamlyn J.M. Biosynthesis of endogenous cardiac glycosides by mammalian adrenocortical cells: three steps forward. Clinical Chemistry 50 3 (2004) 469-470
    • (2004) Clinical Chemistry , vol.50 , Issue.3 , pp. 469-470
    • Hamlyn, J.M.1
  • 78
    • 0014653123 scopus 로고
    • Antineoplastic principles in plants: recent developments in the field
    • Hartwell J.L., and Abbott B.J. Antineoplastic principles in plants: recent developments in the field. Advances in Pharmacology 7 (1969) 117-209
    • (1969) Advances in Pharmacology , vol.7 , pp. 117-209
    • Hartwell, J.L.1    Abbott, B.J.2
  • 81
    • 0033383637 scopus 로고    scopus 로고
    • Digitoxin is a potential anticancer agent for several types of cancer
    • Haux J. Digitoxin is a potential anticancer agent for several types of cancer. Medical Hypotheses 53 6 (1999) 543-548
    • (1999) Medical Hypotheses , vol.53 , Issue.6 , pp. 543-548
    • Haux, J.1
  • 83
    • 0032811793 scopus 로고    scopus 로고
    • Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats
    • Huang B.S., and Leenen F.H. Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats. Hypertension 34 1 (1999) 107-112
    • (1999) Hypertension , vol.34 , Issue.1 , pp. 107-112
    • Huang, B.S.1    Leenen, F.H.2
  • 84
    • 1642534349 scopus 로고    scopus 로고
    • Investigation of ouabain-induced anticancer effect in human androgen-independent prostate cancer PC-3 cells
    • Huang Y.T., Chueh S.C., Teng C.M., and Guh J.H. Investigation of ouabain-induced anticancer effect in human androgen-independent prostate cancer PC-3 cells. Biochemical Pharmacology 67 4 (2004) 727-733
    • (2004) Biochemical Pharmacology , vol.67 , Issue.4 , pp. 727-733
    • Huang, Y.T.1    Chueh, S.C.2    Teng, C.M.3    Guh, J.H.4
  • 85
    • 33748196482 scopus 로고    scopus 로고
    • The central role of the brain in salt-sensitive hypertension
    • Huang B.S., Amin M.S., and Leenen F.H. The central role of the brain in salt-sensitive hypertension. Current opinion in cardiology 21 4 (2006) 295-304
    • (2006) Current opinion in cardiology , vol.21 , Issue.4 , pp. 295-304
    • Huang, B.S.1    Amin, M.S.2    Leenen, F.H.3
  • 86
    • 0242500846 scopus 로고    scopus 로고
    • Digitalis-like immunoreactive substances in maternal and umbilical cord plasma: a comparative sensitivity study of fluorescence polarization immunoassay and microparticle enzyme immunoassay
    • Ijiri Y., Hayashi T., Kamegai H., Ohi K., Suzuki K., Kitaura Y., and Takenaka H. Digitalis-like immunoreactive substances in maternal and umbilical cord plasma: a comparative sensitivity study of fluorescence polarization immunoassay and microparticle enzyme immunoassay. Therapeutic Drug Monitoring 25 2 (2003) 234-239
    • (2003) Therapeutic Drug Monitoring , vol.25 , Issue.2 , pp. 234-239
    • Ijiri, Y.1    Hayashi, T.2    Kamegai, H.3    Ohi, K.4    Suzuki, K.5    Kitaura, Y.6    Takenaka, H.7
  • 87
    • 0028334058 scopus 로고
    • Selective inhibitory effect of bufalin on growth of human tumor cells in vitro: association with the induction of apoptosis in leukemia HL-60 cells
    • Jing Y., Ohizumi H., Kawazoe N., Hashimoto S., Masuda Y., Nakajo S., Yoshida T., Kuroiwa Y., and Nakaya K. Selective inhibitory effect of bufalin on growth of human tumor cells in vitro: association with the induction of apoptosis in leukemia HL-60 cells. Japanese Journal of Cancer Research 85 6 (1994) 645-651
    • (1994) Japanese Journal of Cancer Research , vol.85 , Issue.6 , pp. 645-651
    • Jing, Y.1    Ohizumi, H.2    Kawazoe, N.3    Hashimoto, S.4    Masuda, Y.5    Nakajo, S.6    Yoshida, T.7    Kuroiwa, Y.8    Nakaya, K.9
  • 88
    • 0038621773 scopus 로고    scopus 로고
    • Structure and mechanism of Na,K-ATPase: functional sites and their interactions
    • Jorgensen P.L., Hakansson K.O., and Karlish S.J. Structure and mechanism of Na,K-ATPase: functional sites and their interactions. Annual Review of Physiology 65 (2003) 817-849
    • (2003) Annual Review of Physiology , vol.65 , pp. 817-849
    • Jorgensen, P.L.1    Hakansson, K.O.2    Karlish, S.J.3
  • 90
    • 0033032559 scopus 로고    scopus 로고
    • Effects of digoxin-specific antibody Fab fragment (Digibind) on blood pressure and renal water-sodium metabolism in 5/6 reduced renal mass hypertensive rats
    • Kaide J., Ura N., Torii T., Nakagawa M., Takada T., and Shimamoto K. Effects of digoxin-specific antibody Fab fragment (Digibind) on blood pressure and renal water-sodium metabolism in 5/6 reduced renal mass hypertensive rats. The American Journal of Hypertension 12 6 (1999) 611-619
    • (1999) The American Journal of Hypertension , vol.12 , Issue.6 , pp. 611-619
    • Kaide, J.1    Ura, N.2    Torii, T.3    Nakagawa, M.4    Takada, T.5    Shimamoto, K.6
  • 93
    • 0002690481 scopus 로고    scopus 로고
    • Pharmacological treatment of heart failure
    • Herdamn J.G., and Limbird L.E. (Eds), McGraw-Hill comp.
    • Kelly R.A., and Smith T.W. Pharmacological treatment of heart failure. In: Herdamn J.G., and Limbird L.E. (Eds). Pharmacological Treatment of Heart Failure (1996), McGraw-Hill comp. 809-838
    • (1996) Pharmacological Treatment of Heart Failure , pp. 809-838
    • Kelly, R.A.1    Smith, T.W.2
  • 94
    • 33845318534 scopus 로고    scopus 로고
    • Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells
    • Khundmiri S.J., Metzler M.A., Ameen M., Amin V., Rane M.J., and Delamere N.A. Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells. American Journal of Physiology. Cell Physiology 291 6 (2006) C1247-C1257
    • (2006) American Journal of Physiology. Cell Physiology , vol.291 , Issue.6
    • Khundmiri, S.J.1    Metzler, M.A.2    Ameen, M.3    Amin, V.4    Rane, M.J.5    Delamere, N.A.6
  • 95
    • 0036818893 scopus 로고    scopus 로고
    • Identification of the cofilin-binding sites in the large cytoplasmic domain of Na,K-ATPase
    • Kim M., Jung J., Park C.S., and Lee K. Identification of the cofilin-binding sites in the large cytoplasmic domain of Na,K-ATPase. Biochimie 84 10 (2002) 1021-1029
    • (2002) Biochimie , vol.84 , Issue.10 , pp. 1021-1029
    • Kim, M.1    Jung, J.2    Park, C.S.3    Lee, K.4
  • 96
    • 0016438157 scopus 로고
    • Increased ouabain-sensitive 86Rb+ uptake and sodium and potassium ion-activated adenosine triphosphatase activity in transformed cell lines
    • Kimelberg H.K., and Mayhew E. Increased ouabain-sensitive 86Rb+ uptake and sodium and potassium ion-activated adenosine triphosphatase activity in transformed cell lines. The Journal of Biological Chemistry 250 1 (1975) 100-104
    • (1975) The Journal of Biological Chemistry , vol.250 , Issue.1 , pp. 100-104
    • Kimelberg, H.K.1    Mayhew, E.2
  • 99
    • 10644255834 scopus 로고    scopus 로고
    • A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure
    • Komiyama Y., Dong X.H., Nishimura N., Masaki H., Yoshika M., Masuda M., and Takahashi H. A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure. Clinical Biochemistry 38 1 (2005) 36-45
    • (2005) Clinical Biochemistry , vol.38 , Issue.1 , pp. 36-45
    • Komiyama, Y.1    Dong, X.H.2    Nishimura, N.3    Masaki, H.4    Yoshika, M.5    Masuda, M.6    Takahashi, H.7
  • 101
    • 19644376385 scopus 로고    scopus 로고
    • The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade
    • Kupzig S., Walker S.A., and Cullen P.J. The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade. Proceedings of the National Academy of Sciences of the United States of America 102 21 (2005) 7577-7582
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.21 , pp. 7577-7582
    • Kupzig, S.1    Walker, S.A.2    Cullen, P.J.3
  • 103
    • 0027991609 scopus 로고
    • Ouabain is secreted by bovine adrenocortical cells
    • Laredo J., Hamilton B.P., and Hamlyn J.M. Ouabain is secreted by bovine adrenocortical cells. Endocrinology 135 2 (1994) 794-797
    • (1994) Endocrinology , vol.135 , Issue.2 , pp. 794-797
    • Laredo, J.1    Hamilton, B.P.2    Hamlyn, J.M.3
  • 104
    • 0029119624 scopus 로고
    • Secretion of endogenous ouabain from bovine adrenocortical cells: role of the zona glomerulosa and zona fasciculata
    • Laredo J., Hamilton B.P., and Hamlyn J.M. Secretion of endogenous ouabain from bovine adrenocortical cells: role of the zona glomerulosa and zona fasciculata. Biochemical and Biophysical Research Communications 212 2 (1995) 487-493
    • (1995) Biochemical and Biophysical Research Communications , vol.212 , Issue.2 , pp. 487-493
    • Laredo, J.1    Hamilton, B.P.2    Hamlyn, J.M.3
  • 105
    • 0031017359 scopus 로고    scopus 로고
    • Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors
    • Laredo J., Shah J.R., Lu Z.R., Hamilton B.P., and Hamlyn J.M. Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors. Hypertension 29 1 Pt 2 (1997) 401-407
    • (1997) Hypertension , vol.29 , Issue.1 PART 2 , pp. 401-407
    • Laredo, J.1    Shah, J.R.2    Lu, Z.R.3    Hamilton, B.P.4    Hamlyn, J.M.5
  • 107
    • 0027320842 scopus 로고
    • Dietary sodium stimulates ouabainlike activity in adrenalectomized spontaneously hypertensive rats
    • Leenen F.H., Harmsen E., Yu H., and Yuan B. Dietary sodium stimulates ouabainlike activity in adrenalectomized spontaneously hypertensive rats. The American Journal of Physiology 265 1 Pt 2 (1993) H421-H424
    • (1993) The American Journal of Physiology , vol.265 , Issue.1 PART 2
    • Leenen, F.H.1    Harmsen, E.2    Yu, H.3    Yuan, B.4
  • 108
    • 0036009909 scopus 로고    scopus 로고
    • NFkappaB-dependent signaling pathways
    • Li X., and Stark G.R. NFkappaB-dependent signaling pathways. Experimental Hematology 30 4 (2002) 285-296
    • (2002) Experimental Hematology , vol.30 , Issue.4 , pp. 285-296
    • Li, X.1    Stark, G.R.2
  • 110
    • 33745818598 scopus 로고    scopus 로고
    • Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB
    • Li J., Zelenin S., Aperia A., and Aizman O. Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB. Journal of the American Society of Nephrology 17 7 (2006) 1848-1857
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.7 , pp. 1848-1857
    • Li, J.1    Zelenin, S.2    Aperia, A.3    Aizman, O.4
  • 111
    • 33745864301 scopus 로고    scopus 로고
    • Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay
    • Liang M., Cai T., Tian J., Qu W., and Xie Z.J. Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay. The Journal of Biological Chemistry 281 28 (2006) 19709-19719
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.28 , pp. 19709-19719
    • Liang, M.1    Cai, T.2    Tian, J.3    Qu, W.4    Xie, Z.J.5
  • 113
    • 0029116579 scopus 로고
    • +-ATPase and heart excitability
    • Sideman S., and Beyar R. (Eds), Plenum Press
    • +-ATPase and heart excitability. In: Sideman S., and Beyar R. (Eds). Advances in Experimental Medicine and Biology (1995), Plenum Press 23-30
    • (1995) Advances in Experimental Medicine and Biology , pp. 23-30
    • Lichtstein, D.1
  • 114
  • 117
    • 0027488551 scopus 로고
    • Digitalis-like compounds in the toad Bufo viridis: interactions with plasma proteins
    • Lichtstein D., Gati I., and Ovadia H. Digitalis-like compounds in the toad Bufo viridis: interactions with plasma proteins. Journal of Cardiovascular Pharmacology 22 Suppl 2 (1993) S102-S105
    • (1993) Journal of Cardiovascular Pharmacology , vol.22 , Issue.SUPPL. 2
    • Lichtstein, D.1    Gati, I.2    Ovadia, H.3
  • 119
    • 0032078274 scopus 로고    scopus 로고
    • Biosynthesis of digitalis-like compounds in rat adrenal cells: hydroxycholesterol as possible precursor
    • Lichtstein D., Steinitz M., Gati I., Samuelov S., Deutsch J., and Orly J. Biosynthesis of digitalis-like compounds in rat adrenal cells: hydroxycholesterol as possible precursor. Life Sciences 62 23 (1998) 2109-2126
    • (1998) Life Sciences , vol.62 , Issue.23 , pp. 2109-2126
    • Lichtstein, D.1    Steinitz, M.2    Gati, I.3    Samuelov, S.4    Deutsch, J.5    Orly, J.6
  • 121
    • 21344447536 scopus 로고    scopus 로고
    • Ouabain-induced endocytosis and signal transduction of the Na/K-ATPase
    • Liu J. Ouabain-induced endocytosis and signal transduction of the Na/K-ATPase. Frontiers in Bioscience 10 (2005) 2056-2063
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2056-2063
    • Liu, J.1
  • 123
    • 0031284661 scopus 로고    scopus 로고
    • Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness
    • Looney S.W., and el-Mallakh R.S. Meta-analysis of erythrocyte Na,K-ATPase activity in bipolar illness. Depression and Anxiety 5 2 (1997) 53-65
    • (1997) Depression and Anxiety , vol.5 , Issue.2 , pp. 53-65
    • Looney, S.W.1    el-Mallakh, R.S.2
  • 124
    • 0028271160 scopus 로고
    • Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure
    • Manunta P., Rogowski A.C., Hamilton B.P., and Hamlyn J.M. Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure. Journal of Hypertension 12 5 (1994) 549-560
    • (1994) Journal of Hypertension , vol.12 , Issue.5 , pp. 549-560
    • Manunta, P.1    Rogowski, A.C.2    Hamilton, B.P.3    Hamlyn, J.M.4
  • 125
    • 0033799448 scopus 로고    scopus 로고
    • Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin
    • Manunta P., Hamilton J., Rogowski A.C., Hamilton B.P., and Hamlyn J.M. Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin. Hypertension Research 23 Suppl (2000) S77-S85
    • (2000) Hypertension Research , vol.23 , Issue.SUPPL
    • Manunta, P.1    Hamilton, J.2    Rogowski, A.C.3    Hamilton, B.P.4    Hamlyn, J.M.5
  • 128
    • 1342280376 scopus 로고    scopus 로고
    • Ouabain exerts biphasic effects on connexin functionality and expression in vascular smooth muscle cells
    • Martin P.E., Hill N.S., Kristensen B., Errington R.J., and Rachael J.T. Ouabain exerts biphasic effects on connexin functionality and expression in vascular smooth muscle cells. British Journal of Pharmacology 141 2 (2004) 374-384
    • (2004) British Journal of Pharmacology , vol.141 , Issue.2 , pp. 374-384
    • Martin, P.E.1    Hill, N.S.2    Kristensen, B.3    Errington, R.J.4    Rachael, J.T.5
  • 130
    • 0023895703 scopus 로고
    • Normalization of high plasma level of ouabain-like immunoreactivity in primary aldosteronism after removal of adenoma
    • Masugi F., Ogihara T., Hasegawa T., Sakaguchi K., and Kumahara Y. Normalization of high plasma level of ouabain-like immunoreactivity in primary aldosteronism after removal of adenoma. Journal of Human Hypertension 2 1 (1988) 17-20
    • (1988) Journal of Human Hypertension , vol.2 , Issue.1 , pp. 17-20
    • Masugi, F.1    Ogihara, T.2    Hasegawa, T.3    Sakaguchi, K.4    Kumahara, Y.5
  • 134
    • 0035233563 scopus 로고    scopus 로고
    • Biosynthesis of neurosteroids and regulation of their synthesis
    • Mellon S.H., and Vaudry H. Biosynthesis of neurosteroids and regulation of their synthesis. International Review of Neurobiology 46 (2001) 33-78
    • (2001) International Review of Neurobiology , vol.46 , pp. 33-78
    • Mellon, S.H.1    Vaudry, H.2
  • 135
    • 0001092926 scopus 로고
    • Collection of toad venoms and chemistry of the toad venom steroids
    • Bucherl W., and Buckley E.E. (Eds), Academic Press, New York
    • Meyer K., and Linde H. Collection of toad venoms and chemistry of the toad venom steroids. In: Bucherl W., and Buckley E.E. (Eds). Collection of Toad Venoms and Chemistry of the Toad Venom Steroids (1971), Academic Press, New York
    • (1971) Collection of Toad Venoms and Chemistry of the Toad Venom Steroids
    • Meyer, K.1    Linde, H.2
  • 136
    • 0031731177 scopus 로고    scopus 로고
    • Early steps in androgen biosynthesis: from cholesterol to DHEA
    • Miller W.L. Early steps in androgen biosynthesis: from cholesterol to DHEA. Bailliere's Clinical Endocrinology and Metabolism 12 1 (1998) 67-81
    • (1998) Bailliere's Clinical Endocrinology and Metabolism , vol.12 , Issue.1 , pp. 67-81
    • Miller, W.L.1
  • 139
    • 2942609688 scopus 로고    scopus 로고
    • Epithelial Na, K-ATPase expression is down-regulated in canine prostate cancer; a possible consequence of metabolic transformation in the process of prostate malignancy
    • Mobasheri A., Fox R., Evans I., Cullingham F., Martin-Vasallo P., and Foster C.S. Epithelial Na, K-ATPase expression is down-regulated in canine prostate cancer; a possible consequence of metabolic transformation in the process of prostate malignancy. Cancer Cell International 3 1 (2003) 8
    • (2003) Cancer Cell International , vol.3 , Issue.1 , pp. 8
    • Mobasheri, A.1    Fox, R.2    Evans, I.3    Cullingham, F.4    Martin-Vasallo, P.5    Foster, C.S.6
  • 143
    • 0023262074 scopus 로고
    • +)ATPase and implications for the organization of membrane domains in polarized cells
    • +)ATPase and implications for the organization of membrane domains in polarized cells. Nature 328 6130 (1987) 533-536
    • (1987) Nature , vol.328 , Issue.6130 , pp. 533-536
    • Nelson, W.J.1    Veshnock, P.J.2
  • 144
    • 33845977762 scopus 로고    scopus 로고
    • Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation
    • Nguyen A.N., Wallace D.P., and Blanco G. Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation. Journal of the American Society of Nephrology 18 1 (2007) 46-57
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.1 , pp. 46-57
    • Nguyen, A.N.1    Wallace, D.P.2    Blanco, G.3
  • 154
    • 0029828012 scopus 로고    scopus 로고
    • Structure and function of the Na,K pump: ten years of molecular biology
    • Pressley T.A. Structure and function of the Na,K pump: ten years of molecular biology. Mineral and Electrolyte Metabolism 22 5-6 (1996) 264-271
    • (1996) Mineral and Electrolyte Metabolism , vol.22 , Issue.5-6 , pp. 264-271
    • Pressley, T.A.1
  • 155
    • 1542358869 scopus 로고    scopus 로고
    • De novo biosynthesis and radiolabeling of mammalian digitalis-like factors
    • Qazzaz H.M., Cao Z., Bolanowski D.D., Clark B.J., and Valdes Jr. R. De novo biosynthesis and radiolabeling of mammalian digitalis-like factors. Clinical Chemistry 50 3 (2004) 612-620
    • (2004) Clinical Chemistry , vol.50 , Issue.3 , pp. 612-620
    • Qazzaz, H.M.1    Cao, Z.2    Bolanowski, D.D.3    Clark, B.J.4    Valdes Jr., R.5
  • 158
    • 84944812792 scopus 로고
    • Regarding the influence of the organic constituents of the blood on the contractility of the ventricle
    • 367
    • Ringer S. Regarding the influence of the organic constituents of the blood on the contractility of the ventricle. The Journal of Physiology 6 6 (1885) 361-463 367
    • (1885) The Journal of Physiology , vol.6 , Issue.6 , pp. 361-463
    • Ringer, S.1
  • 160
    • 0001954570 scopus 로고    scopus 로고
    • Antiarrhythmic drugs
    • Hardman J.G., Limbird L.E., Molinoff P.B., and Ruddon R.W. (Eds), McGraw-Hill, NY
    • Roden D.M. Antiarrhythmic drugs. In: Hardman J.G., Limbird L.E., Molinoff P.B., and Ruddon R.W. (Eds). Antiarrhythmic Drugs (1996), McGraw-Hill, NY 839-874
    • (1996) Antiarrhythmic Drugs , pp. 839-874
    • Roden, D.M.1
  • 161
    • 1542283814 scopus 로고    scopus 로고
    • Cardiac steroids induce changes in recycling of the plasma membrane in human NT2 cells
    • Rosen H., Glukhman V., Feldmann T., Fridman E., and Lichtstein D. Cardiac steroids induce changes in recycling of the plasma membrane in human NT2 cells. Molecular Biology of the Cell 15 3 (2004) 1044-1054
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.3 , pp. 1044-1054
    • Rosen, H.1    Glukhman, V.2    Feldmann, T.3    Fridman, E.4    Lichtstein, D.5
  • 162
    • 0028788618 scopus 로고
    • Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels
    • Rossi G., Manunta P., Hamlyn J.M., Pavan E., De Toni R., Semplicini A., and Pessina A.C. Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. Journal of Hypertension 13 10 (1995) 1181-1191
    • (1995) Journal of Hypertension , vol.13 , Issue.10 , pp. 1181-1191
    • Rossi, G.1    Manunta, P.2    Hamlyn, J.M.3    Pavan, E.4    De Toni, R.5    Semplicini, A.6    Pessina, A.C.7
  • 163
    • 0032007870 scopus 로고    scopus 로고
    • Persistent hyperactivity following a single intracerebroventricular dose of ouabain
    • Ruktanonchai D.J., El-Mallakh R.S., Li R., and Levy R.S. Persistent hyperactivity following a single intracerebroventricular dose of ouabain. Physiology & Behavior 63 3 (1998) 403-406
    • (1998) Physiology & Behavior , vol.63 , Issue.3 , pp. 403-406
    • Ruktanonchai, D.J.1    El-Mallakh, R.S.2    Li, R.3    Levy, R.S.4
  • 164
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives
    • Rupprecht R., and Holsboer F. Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives. Trends in Neurosciences 22 9 (1999) 410-416
    • (1999) Trends in Neurosciences , vol.22 , Issue.9 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 166
    • 1542374561 scopus 로고    scopus 로고
    • Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump
    • Saunders R., and Scheiner-Bobis G. Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump. European Journal of Biochemistry/FEBS 271 5 (2004) 1054-1062
    • (2004) European Journal of Biochemistry/FEBS , vol.271 , Issue.5 , pp. 1054-1062
    • Saunders, R.1    Scheiner-Bobis, G.2
  • 167
    • 0035667677 scopus 로고    scopus 로고
    • A fresh facet for ouabain action
    • Scheiner-Bobis G., and Schoner W. A fresh facet for ouabain action. Nature Medicine 7 12 (2001) 1288-1289
    • (2001) Nature Medicine , vol.7 , Issue.12 , pp. 1288-1289
    • Scheiner-Bobis, G.1    Schoner, W.2
  • 168
    • 0031822851 scopus 로고    scopus 로고
    • Proscillaridin A immunoreactivity: its purification, transport in blood by a specific binding protein and its correlation with blood pressure
    • Schneider R., Antolovic R., Kost H., Sich B., Kirch U., Tepel M., Zidek W., and Schoner W. Proscillaridin A immunoreactivity: its purification, transport in blood by a specific binding protein and its correlation with blood pressure. Clinical and Experimental Hypertension 20 5-6 (1998) 593-599
    • (1998) Clinical and Experimental Hypertension , vol.20 , Issue.5-6 , pp. 593-599
    • Schneider, R.1    Antolovic, R.2    Kost, H.3    Sich, B.4    Kirch, U.5    Tepel, M.6    Zidek, W.7    Schoner, W.8
  • 169
    • 0036106788 scopus 로고    scopus 로고
    • Endogenous cardiac glycosides, a new class of steroid hormones
    • Schoner W. Endogenous cardiac glycosides, a new class of steroid hormones. European Journal of Biochemistry/FEBS 269 10 (2002) 2440-2448
    • (2002) European Journal of Biochemistry/FEBS , vol.269 , Issue.10 , pp. 2440-2448
    • Schoner, W.1
  • 171
    • 0031601855 scopus 로고    scopus 로고
    • Different signaling pathways mediate stimulated secretions of endogenous ouabain and aldosterone from bovine adrenocortical cells
    • Shah J.R., Laredo J., Hamilton B.P., and Hamlyn J.M. Different signaling pathways mediate stimulated secretions of endogenous ouabain and aldosterone from bovine adrenocortical cells. Hypertension 31 1 Pt 2 (1998) 463-468
    • (1998) Hypertension , vol.31 , Issue.1 PART 2 , pp. 463-468
    • Shah, J.R.1    Laredo, J.2    Hamilton, B.P.3    Hamlyn, J.M.4
  • 173
    • 0018088023 scopus 로고
    • Alteration of sodium transport in mouse mammary epithelium associated with neoplastic transformation
    • Shen S.S., Hamamoto S.T., Bern H.A., and Steinhardt R.A. Alteration of sodium transport in mouse mammary epithelium associated with neoplastic transformation. Cancer Research 38 5 (1978) 1356-1361
    • (1978) Cancer Research , vol.38 , Issue.5 , pp. 1356-1361
    • Shen, S.S.1    Hamamoto, S.T.2    Bern, H.A.3    Steinhardt, R.A.4
  • 174
    • 0014187807 scopus 로고
    • Growth inhibitory effect of cardiac glycosides and aglycones on neoplastic cells: in vitro and in vivo studies
    • Shiratori O. Growth inhibitory effect of cardiac glycosides and aglycones on neoplastic cells: in vitro and in vivo studies. Gan Gann; The Japanese Journal of Cancer Research 58 6 (1967) 521-528
    • (1967) Gan Gann; The Japanese Journal of Cancer Research , vol.58 , Issue.6 , pp. 521-528
    • Shiratori, O.1
  • 175
    • 0032973950 scopus 로고    scopus 로고
    • New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase
    • Sirover M.A. New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. Biochimica et Biophysica Acta 1432 2 (1999) 159-184
    • (1999) Biochimica et Biophysica Acta , vol.1432 , Issue.2 , pp. 159-184
    • Sirover, M.A.1
  • 176
    • 23844452781 scopus 로고    scopus 로고
    • New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells
    • Sirover M.A. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. Journal of Cellular Biochemistry 95 1 (2005) 45-52
    • (2005) Journal of Cellular Biochemistry , vol.95 , Issue.1 , pp. 45-52
    • Sirover, M.A.1
  • 177
    • 0142120501 scopus 로고    scopus 로고
    • Circulating endogenous digitalis-like factor(s) (EDLF) in man is derived from the adrenals and its secretion is ACTH-dependent
    • Sophocleous A., Elmatzoglou I., and Souvatzoglou A. Circulating endogenous digitalis-like factor(s) (EDLF) in man is derived from the adrenals and its secretion is ACTH-dependent. Journal of Endocrinological Investigation 26 7 (2003) 668-674
    • (2003) Journal of Endocrinological Investigation , vol.26 , Issue.7 , pp. 668-674
    • Sophocleous, A.1    Elmatzoglou, I.2    Souvatzoglou, A.3
  • 178
    • 0033129591 scopus 로고    scopus 로고
    • Is digitalis a therapy for breast carcinoma?
    • Stenkvist B. Is digitalis a therapy for breast carcinoma?. Oncology Reports 6 3 (1999) 493-496
    • (1999) Oncology Reports , vol.6 , Issue.3 , pp. 493-496
    • Stenkvist, B.1
  • 179
    • 0035047848 scopus 로고    scopus 로고
    • StAR protein and the regulation of steroid hormone biosynthesis
    • Stocco D.M. StAR protein and the regulation of steroid hormone biosynthesis. Annual Review of Physiology 63 (2001) 193-213
    • (2001) Annual Review of Physiology , vol.63 , pp. 193-213
    • Stocco, D.M.1
  • 180
    • 34248574988 scopus 로고
    • Chemical physiology of contraction
    • Academic Press, New York
    • Szent-Gyorgyi A. Chemical physiology of contraction. Body and Heart Muscle (1953), Academic Press, New York 86-91
    • (1953) Body and Heart Muscle , pp. 86-91
    • Szent-Gyorgyi, A.1
  • 181
    • 0037106312 scopus 로고    scopus 로고
    • c-Fos expression in ouabain-treated vascular smooth muscle cells from rat aorta: evidence for an intracellular-sodium-mediated, calcium-independent mechanism
    • Taurin S., Dulin N.O., Pchejetski D., Grygorczyk R., Tremblay J., Hamet P., and Orlov S.N. c-Fos expression in ouabain-treated vascular smooth muscle cells from rat aorta: evidence for an intracellular-sodium-mediated, calcium-independent mechanism. The Journal of Physiology 543 Pt 3 (2002) 835-847
    • (2002) The Journal of Physiology , vol.543 , Issue.PART 3 , pp. 835-847
    • Taurin, S.1    Dulin, N.O.2    Pchejetski, D.3    Grygorczyk, R.4    Tremblay, J.5    Hamet, P.6    Orlov, S.N.7
  • 182
    • 0035123947 scopus 로고    scopus 로고
    • The T-cell suppressive effect of bufadienolides: structural requirements for their immunoregulatory activity
    • Terness P., Navolan D., Dufter C., Kopp B., and Opelz G. The T-cell suppressive effect of bufadienolides: structural requirements for their immunoregulatory activity. International Immunopharmacology 1 1 (2001) 119-134
    • (2001) International Immunopharmacology , vol.1 , Issue.1 , pp. 119-134
    • Terness, P.1    Navolan, D.2    Dufter, C.3    Kopp, B.4    Opelz, G.5
  • 187
    • 0035666911 scopus 로고    scopus 로고
    • Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging
    • Vallee M., Mayo W., and Le Moal M. Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging. Brain Research 37 1-3 (2001) 301-312
    • (2001) Brain Research , vol.37 , Issue.1-3 , pp. 301-312
    • Vallee, M.1    Mayo, W.2    Le Moal, M.3
  • 188
    • 0031034114 scopus 로고    scopus 로고
    • Excitotoxic lesions of the ventral anteroventral third ventricle and pressor responses to central sodium, ouabain and angiotensin II
    • Veerasingham S.J., and Leenen F.H. Excitotoxic lesions of the ventral anteroventral third ventricle and pressor responses to central sodium, ouabain and angiotensin II. Brain Research 749 1 (1997) 157-160
    • (1997) Brain Research , vol.749 , Issue.1 , pp. 157-160
    • Veerasingham, S.J.1    Leenen, F.H.2
  • 189
    • 0032897214 scopus 로고    scopus 로고
    • Ouabain- and central sodium-induced hypertension depend on the ventral anteroventral third ventricle region
    • Veerasingham S.J., and Leenen F.H. Ouabain- and central sodium-induced hypertension depend on the ventral anteroventral third ventricle region. The American Journal of Physiology 276 1 Pt 2 (1999) H63-H70
    • (1999) The American Journal of Physiology , vol.276 , Issue.1 PART 2
    • Veerasingham, S.J.1    Leenen, F.H.2
  • 191
    • 0030855164 scopus 로고    scopus 로고
    • Bcl-2 protein inhibits bufalin-induced apoptosis through inhibition of mitogen-activated protein kinase activation in human leukemia U937 cells
    • Watabe M., Kawazoe N., Masuda Y., Nakajo S., and Nakaya K. Bcl-2 protein inhibits bufalin-induced apoptosis through inhibition of mitogen-activated protein kinase activation in human leukemia U937 cells. Cancer Research 57 15 (1997) 3097-3100
    • (1997) Cancer Research , vol.57 , Issue.15 , pp. 3097-3100
    • Watabe, M.1    Kawazoe, N.2    Masuda, Y.3    Nakajo, S.4    Nakaya, K.5
  • 192
    • 21344468869 scopus 로고    scopus 로고
    • Na/K-ATPase, endogenous digitalis like compounds and cancer development - a hypothesis
    • Weidemann H. Na/K-ATPase, endogenous digitalis like compounds and cancer development - a hypothesis. Frontiers in Bioscience 10 (2005) 2165-2176
    • (2005) Frontiers in Bioscience , vol.10 , pp. 2165-2176
    • Weidemann, H.1
  • 193
    • 2942611427 scopus 로고    scopus 로고
    • Diverse effects of stress and additional adrenocorticotropic hormone on digitalis-like compounds in normal and nude mice
    • Weidemann H., Salomon N., Avnit-Sagi T., Weidenfeld J., Rosen H., and Lichtstein D. Diverse effects of stress and additional adrenocorticotropic hormone on digitalis-like compounds in normal and nude mice. Journal of Neuroendocrinology 16 5 (2004) 458-463
    • (2004) Journal of Neuroendocrinology , vol.16 , Issue.5 , pp. 458-463
    • Weidemann, H.1    Salomon, N.2    Avnit-Sagi, T.3    Weidenfeld, J.4    Rosen, H.5    Lichtstein, D.6
  • 195
    • 2342487353 scopus 로고    scopus 로고
    • +-ATPase-mediated signal transduction: from protein interaction to cellular function
    • +-ATPase-mediated signal transduction: from protein interaction to cellular function. Molecular Interventions 3 3 (2003) 157-168
    • (2003) Molecular Interventions , vol.3 , Issue.3 , pp. 157-168
    • Xie, Z.1    Cai, T.2
  • 196
    • 21344450768 scopus 로고    scopus 로고
    • The Na/K-ATPase-mediated signal transduction as a target for new drug development
    • Xie Z., and Xie J. The Na/K-ATPase-mediated signal transduction as a target for new drug development. Frontiers in Bioscience 10 (2005) 3100-3109
    • (2005) Frontiers in Bioscience , vol.10 , pp. 3100-3109
    • Xie, Z.1    Xie, J.2
  • 198
    • 0030973806 scopus 로고    scopus 로고
    • Adrenocorticotropin-induced hypertension in rats: role of ouabain-like compound
    • Yamada K., Goto A., and Omata M. Adrenocorticotropin-induced hypertension in rats: role of ouabain-like compound. American Journal of Hypertension 10 4 Pt 1 (1997) 403-408
    • (1997) American Journal of Hypertension , vol.10 , Issue.4 PART 1 , pp. 403-408
    • Yamada, K.1    Goto, A.2    Omata, M.3
  • 200
    • 2342462928 scopus 로고    scopus 로고
    • Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes
    • You L. Steroid hormone biotransformation and xenobiotic induction of hepatic steroid metabolizing enzymes. Chemico-Biological Interactions 147 3 (2004) 233-246
    • (2004) Chemico-Biological Interactions , vol.147 , Issue.3 , pp. 233-246
    • You, L.1
  • 202
    • 24344485458 scopus 로고    scopus 로고
    • Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex
    • Yuan Z., Cai T., Tian J., Ivanov A.V., Giovannucci D.R., and Xie Z. Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex. Molecular Biology of the Cell 16 9 (2005) 4034-4045
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.9 , pp. 4034-4045
    • Yuan, Z.1    Cai, T.2    Tian, J.3    Ivanov, A.V.4    Giovannucci, D.R.5    Xie, Z.6
  • 204
    • 0026760925 scopus 로고
    • Induction by bufalin of differentiation of human leukemia cells HL60, U937, and ML1 toward macrophage/monocyte-like cells and its potent synergistic effect on the differentiation of human leukemia cells in combination with other inducers
    • Zhang L., Nakaya K., Yoshida T., and Kuroiwa Y. Induction by bufalin of differentiation of human leukemia cells HL60, U937, and ML1 toward macrophage/monocyte-like cells and its potent synergistic effect on the differentiation of human leukemia cells in combination with other inducers. Cancer Research 52 17 (1992) 4634-4641
    • (1992) Cancer Research , vol.52 , Issue.17 , pp. 4634-4641
    • Zhang, L.1    Nakaya, K.2    Yoshida, T.3    Kuroiwa, Y.4


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