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Volumn 589, Issue 7, 2011, Pages 1831-1846

Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROLINE RICH PROTEIN; PROTEIN KINASE B; RNA; SOMATOMEDIN C; TUBERIN;

EID: 79953152152     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.205658     Document Type: Article
Times cited : (152)

References (52)
  • 1
    • 0030455045 scopus 로고    scopus 로고
    • The relationships among IGF-1, DNA content, and protein accumulation during skeletal muscle hypertrophy
    • Adams GR & Haddad F (1996). The relationships among IGF-1, DNA content, and protein accumulation during skeletal muscle hypertrophy. J Appl Physiol 81, 2509-2516.
    • (1996) J Appl Physiol , vol.81 , pp. 2509-2516
    • Adams, G.R.1    Haddad, F.2
  • 2
    • 0032748436 scopus 로고    scopus 로고
    • Time course of changes in markers of myogenesis in overloaded rat skeletal muscles
    • Adams GR, Haddad F & Baldwin KM (1999). Time course of changes in markers of myogenesis in overloaded rat skeletal muscles. J Appl Physiol 87, 1705-1712.
    • (1999) J Appl Physiol , vol.87 , pp. 1705-1712
    • Adams, G.R.1    Haddad, F.2    Baldwin, K.M.3
  • 3
    • 0031965872 scopus 로고    scopus 로고
    • Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats
    • Adams GR & McCue SA (1998). Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats. J Appl Physiol 84, 1716-1722.
    • (1998) J Appl Physiol , vol.84 , pp. 1716-1722
    • Adams, G.R.1    McCue, S.A.2
  • 4
    • 52449095361 scopus 로고    scopus 로고
    • The RSK family of kinases: emerging roles in cellular signalling
    • Anjum R & Blenis J (2008). The RSK family of kinases: emerging roles in cellular signalling. Nat Rev Mol Cell Biol 9, 747-758.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 747-758
    • Anjum, R.1    Blenis, J.2
  • 5
    • 0032948278 scopus 로고    scopus 로고
    • Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise
    • Baar K & Esser K (1999). Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise. Am J Physiol Cell Physiol 276, C120-C127.
    • (1999) Am J Physiol Cell Physiol , vol.276
    • Baar, K.1    Esser, K.2
  • 6
    • 14144254701 scopus 로고    scopus 로고
    • Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
    • Ballif BA, Roux PP, Gerber SA, MacKeigan JP, Blenis J & Gygi SP (2005). Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. Proc Natl Acad Sci U S A 102, 667-672.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 667-672
    • Ballif, B.A.1    Roux, P.P.2    Gerber, S.A.3    MacKeigan, J.P.4    Blenis, J.5    Gygi, S.P.6
  • 10
    • 0024355048 scopus 로고
    • Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations
    • Daughaday WH & Rotwein P (1989). Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 10, 68-91.
    • (1989) Endocr Rev , vol.10 , pp. 68-91
    • Daughaday, W.H.1    Rotwein, P.2
  • 14
    • 0035115052 scopus 로고    scopus 로고
    • Selected contribution: IGF-I antibody prevents increases in protein synthesis in epitrochlearis muscles from refed, diabetic rats
    • discussion 1165.
    • Fedele MJ, Vary TC & Farrell PA (2001). Selected contribution: IGF-I antibody prevents increases in protein synthesis in epitrochlearis muscles from refed, diabetic rats. J Appl Physiol 90, 1166-1173; discussion 1165.
    • (2001) J Appl Physiol , vol.90 , pp. 1166-1173
    • Fedele, M.J.1    Vary, T.C.2    Farrell, P.A.3
  • 15
    • 34447644976 scopus 로고    scopus 로고
    • Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass
    • Frost RA & Lang CH (2007). Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass. J Appl Physiol 103, 378-387.
    • (2007) J Appl Physiol , vol.103 , pp. 378-387
    • Frost, R.A.1    Lang, C.H.2
  • 16
    • 23944456384 scopus 로고    scopus 로고
    • Skeletal muscle hypertrophy and atrophy signaling pathways
    • Glass DJ (2005). Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol 37, 1974-1984.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1974-1984
    • Glass, D.J.1
  • 17
    • 0014147822 scopus 로고
    • Work-induced growth of skeletal muscle in normal and hypophysectomized rats
    • Goldberg AL (1967). Work-induced growth of skeletal muscle in normal and hypophysectomized rats. Am J Physiol 213, 1193-1198.
    • (1967) Am J Physiol , vol.213 , pp. 1193-1198
    • Goldberg, A.L.1
  • 20
    • 3042820402 scopus 로고    scopus 로고
    • Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism
    • Hornberger TA, Stuppard R, Conley KE, Fedele MJ, Fiorotto ML, Chin ER & Esser KA (2004). Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. Biochem J 380, 795-804.
    • (2004) Biochem J , vol.380 , pp. 795-804
    • Hornberger, T.A.1    Stuppard, R.2    Conley, K.E.3    Fedele, M.J.4    Fiorotto, M.L.5    Chin, E.R.6    Esser, K.A.7
  • 21
    • 0025345403 scopus 로고
    • Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution
    • Horne Z & Hesketh J (1990). Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution. Biochem J 268, 231-236.
    • (1990) Biochem J , vol.268 , pp. 231-236
    • Horne, Z.1    Hesketh, J.2
  • 22
    • 44449161481 scopus 로고    scopus 로고
    • The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
    • Huang J & Manning BD (2008). The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem J 412, 179-190.
    • (2008) Biochem J , vol.412 , pp. 179-190
    • Huang, J.1    Manning, B.D.2
  • 23
    • 0043127125 scopus 로고    scopus 로고
    • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
    • Inoki K, Li Y, Xu T & Guan KL (2003). Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev 17, 1829-1834.
    • (2003) Genes Dev , vol.17 , pp. 1829-1834
    • Inoki, K.1    Li, Y.2    Xu, T.3    Guan, K.L.4
  • 24
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki K, Li Y, Zhu T, Wu J & Guan KL (2002). TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4, 648-657.
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 25
    • 0024508118 scopus 로고
    • Growth hormone regulates the level of insulin-like growth factor-I mRNA in rat skeletal muscle
    • Isgaard J, Nilsson A, Vikman K & Isaksson OG (1989). Growth hormone regulates the level of insulin-like growth factor-I mRNA in rat skeletal muscle. J Endocrinol 120, 107-112.
    • (1989) J Endocrinol , vol.120 , pp. 107-112
    • Isgaard, J.1    Nilsson, A.2    Vikman, K.3    Isaksson, O.G.4
  • 26
    • 0037312507 scopus 로고    scopus 로고
    • Tor signalling in bugs, brain and brawn
    • Jacinto E & Hall MN (2003). Tor signalling in bugs, brain and brawn. Nat Rev Mol Cell Biol 4, 117-126.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 117-126
    • Jacinto, E.1    Hall, M.N.2
  • 27
    • 14844302667 scopus 로고    scopus 로고
    • Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Be{open} mRNA in a mammalian target of rapamycin-dependent manner
    • Kubica N, Bolster DR, Farrell PA, Kimball SR & Jefferson LS (2005). Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Be{open} mRNA in a mammalian target of rapamycin-dependent manner. J Biol Chem 280, 7570-7580.
    • (2005) J Biol Chem , vol.280 , pp. 7570-7580
    • Kubica, N.1    Bolster, D.R.2    Farrell, P.A.3    Kimball, S.R.4    Jefferson, L.S.5
  • 29
    • 70350418625 scopus 로고    scopus 로고
    • mTOR signaling at a glance
    • Laplante M & Sabatini DM (2009). mTOR signaling at a glance. J Cell Sci 122, 3589-3594.
    • (2009) J Cell Sci , vol.122 , pp. 3589-3594
    • Laplante, M.1    Sabatini, D.M.2
  • 30
  • 31
    • 34547645033 scopus 로고    scopus 로고
    • Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer
    • Ma L, Teruya-Feldstein J, Bonner P, Bernardi R, Franz DN, Witte D, Cordon-Cardo C & Pandolfi PP (2007). Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer Res 67, 7106-7112.
    • (2007) Cancer Res , vol.67 , pp. 7106-7112
    • Ma, L.1    Teruya-Feldstein, J.2    Bonner, P.3    Bernardi, R.4    Franz, D.N.5    Witte, D.6    Cordon-Cardo, C.7    Pandolfi, P.P.8
  • 32
    • 33846153786 scopus 로고    scopus 로고
    • MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy
    • McCarthy JJ & Esser KA (2007). MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy. J Appl Physiol 102, 306-313.
    • (2007) J Appl Physiol , vol.102 , pp. 306-313
    • McCarthy, J.J.1    Esser, K.A.2
  • 33
    • 60549114181 scopus 로고    scopus 로고
    • Serum IGF-I-deficiency does not prevent compensatory skeletal muscle hypertrophy in resistance exercise
    • Matheny W, Merritt E, Zannikos SV, Farrar RP & Adamo ML (2009). Serum IGF-I-deficiency does not prevent compensatory skeletal muscle hypertrophy in resistance exercise. Exp Biol Med (Maywood) 234, 164-170.
    • (2009) Exp Biol Med (Maywood) , vol.234 , pp. 164-170
    • Matheny, W.1    Merritt, E.2    Zannikos, S.V.3    Farrar, R.P.4    Adamo, M.L.5
  • 34
    • 66149100909 scopus 로고    scopus 로고
    • Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals
    • Miyazaki M & Esser KA (2009a). Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals. J Appl Physiol 106, 1367-1373.
    • (2009) J Appl Physiol , vol.106 , pp. 1367-1373
    • Miyazaki, M.1    Esser, K.A.2
  • 35
    • 65249157359 scopus 로고    scopus 로고
    • REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch
    • Miyazaki M & Esser KA (2009b). REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch. Am J Physiol Cell Physiol 296, C583-C592.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Miyazaki, M.1    Esser, K.A.2
  • 36
    • 11144237638 scopus 로고    scopus 로고
    • Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition
    • Miyazaki M, Hitomi Y, Kizaki T, Ohno H, Haga S & Takemasa T (2004). Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition. J Physiol Pharmacol 55, 751-764.
    • (2004) J Physiol Pharmacol , vol.55 , pp. 751-764
    • Miyazaki, M.1    Hitomi, Y.2    Kizaki, T.3    Ohno, H.4    Haga, S.5    Takemasa, T.6
  • 37
    • 77951213258 scopus 로고    scopus 로고
    • Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes
    • Miyazaki M, McCarthy JJ & Esser KA (2010). Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes. FEBS J 277, 2180-2191.
    • (2010) FEBS J , vol.277 , pp. 2180-2191
    • Miyazaki, M.1    McCarthy, J.J.2    Esser, K.A.3
  • 38
    • 0035055777 scopus 로고    scopus 로고
    • Intracellular signaling specificity in skeletal muscle in response to different modes of exercise
    • Nader GA & Esser KA (2001). Intracellular signaling specificity in skeletal muscle in response to different modes of exercise. J Appl Physiol 90, 1936-1942.
    • (2001) J Appl Physiol , vol.90 , pp. 1936-1942
    • Nader, G.A.1    Esser, K.A.2
  • 39
    • 27744549321 scopus 로고    scopus 로고
    • mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators
    • Nader GA, McLoughlin TJ & Esser KA (2005). mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators. Am J Physiol Cell Physiol 289, C1457-C1465.
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Nader, G.A.1    McLoughlin, T.J.2    Esser, K.A.3
  • 41
    • 67651096033 scopus 로고    scopus 로고
    • The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions
    • O'Neil TK, Duffy LR, Frey JW & Hornberger TA (2009). The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions. J Physiol 587, 3691-3701.
    • (2009) J Physiol , vol.587 , pp. 3691-3701
    • O'Neil, T.K.1    Duffy, L.R.2    Frey, J.W.3    Hornberger, T.A.4
  • 42
    • 11144356304 scopus 로고    scopus 로고
    • S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
    • Pende M, Um SH, Mieulet V, Sticker M, Goss VL, Mestan J, Mueller M, Fumagalli S, Kozma SC & Thomas G (2004). S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol 24, 3112-3124.
    • (2004) Mol Cell Biol , vol.24 , pp. 3112-3124
    • Pende, M.1    Um, S.H.2    Mieulet, V.3    Sticker, M.4    Goss, V.L.5    Mestan, J.6    Mueller, M.7    Fumagalli, S.8    Kozma, S.C.9    Thomas, G.10
  • 44
    • 34347242470 scopus 로고    scopus 로고
    • RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
    • Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N & Blenis J (2007). RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 282, 14056-14064.
    • (2007) J Biol Chem , vol.282 , pp. 14056-14064
    • Roux, P.P.1    Shahbazian, D.2    Vu, H.3    Holz, M.K.4    Cohen, M.S.5    Taunton, J.6    Sonenberg, N.7    Blenis, J.8
  • 47
    • 67651227757 scopus 로고    scopus 로고
    • Changes in muscle mass with mechanical load: possible cellular mechanisms
    • Spangenburg EE (2009). Changes in muscle mass with mechanical load: possible cellular mechanisms. Appl Physiol Nutr Metab 34, 328-335.
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 328-335
    • Spangenburg, E.E.1
  • 48
    • 37749027195 scopus 로고    scopus 로고
    • A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy
    • Spangenburg EE, Le Roith D, Ward CW & Bodine SC (2008). A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy. J Physiol 586, 283-291.
    • (2008) J Physiol , vol.586 , pp. 283-291
    • Spangenburg, E.E.1    Le Roith, D.2    Ward, C.W.3    Bodine, S.C.4
  • 49
    • 0032557646 scopus 로고    scopus 로고
    • Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB
    • van Weeren PC, de Bruyn KM, de Vries-Smits AM, van Lint J & Burgering BM (1998). Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB. J Biol Chem 273, 13150-13156.
    • (1998) J Biol Chem , vol.273 , pp. 13150-13156
    • van Weeren, P.C.1    de Bruyn, K.M.2    de Vries-Smits, A.M.3    van Lint, J.4    Burgering, B.M.5
  • 51
    • 77953695333 scopus 로고    scopus 로고
    • High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways
    • Witkowski S, Lovering RM & Spangenburg EE (2010). High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways. FEBS Lett 584, 2891-2895.
    • (2010) FEBS Lett , vol.584 , pp. 2891-2895
    • Witkowski, S.1    Lovering, R.M.2    Spangenburg, E.E.3


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