Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway

Circulation

Volumn 107, Issue 24, 2003, Pages 3081-3087

  Bolz, Steffen Sebastian ^a   Vogel, Lukas ^a   Sollinger, Daniel ^a   Derwand, Roland ^a   De Wit, Cor ^a   Loirand, Gervaise ^b   Pohl, Ulrich ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

Microcirculation; Muscle, smooth; Nitric oxide; Signal transduction; Vasodilation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALYCULIN A; CYCLIC GMP; GUANYLATE CYCLASE INHIBITOR; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN PHOSPHATASE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; RHO KINASE; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; HAMSTER; MICROCIRCULATION; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; RESISTANCE BLOOD VESSEL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ADP RIBOSE TRANSFERASES; ANIMALS; ARTERIES; BOTULINUM TOXINS; CALCIUM; CRICETINAE; CYCLIC GMP; ENZYME INHIBITORS; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYSOPHOSPHOLIPIDS; MUSCLES; MUTAGENESIS, SITE-DIRECTED; MYOSIN-LIGHT-CHAIN PHOSPHATASE; NITRIC OXIDE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN-SERINE-THREONINE KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SPHINGOSINE; TRANSFECTION; VASCULAR PATENCY; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0038338555     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000074202.19612.8C     Document Type: Article

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